JP2015503562A5 - - Google Patents

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Publication number
JP2015503562A5
JP2015503562A5 JP2014550353A JP2014550353A JP2015503562A5 JP 2015503562 A5 JP2015503562 A5 JP 2015503562A5 JP 2014550353 A JP2014550353 A JP 2014550353A JP 2014550353 A JP2014550353 A JP 2014550353A JP 2015503562 A5 JP2015503562 A5 JP 2015503562A5
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JP
Japan
Prior art keywords
disease
methyl
condition
carboxylic acid
pyrazole
Prior art date
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Granted
Application number
JP2014550353A
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English (en)
Japanese (ja)
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JP6132853B2 (ja
JP2015503562A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/070664 external-priority patent/WO2013101598A1/en
Publication of JP2015503562A publication Critical patent/JP2015503562A/ja
Publication of JP2015503562A5 publication Critical patent/JP2015503562A5/ja
Application granted granted Critical
Publication of JP6132853B2 publication Critical patent/JP6132853B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014550353A 2011-12-27 2012-12-19 全身性抗炎症反応を提供する、複数のプロスタグランジン受容体で作用する化合物 Expired - Fee Related JP6132853B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161580474P 2011-12-27 2011-12-27
US61/580,474 2011-12-27
PCT/US2012/070664 WO2013101598A1 (en) 2011-12-27 2012-12-19 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response

Publications (3)

Publication Number Publication Date
JP2015503562A JP2015503562A (ja) 2015-02-02
JP2015503562A5 true JP2015503562A5 (OSRAM) 2016-02-18
JP6132853B2 JP6132853B2 (ja) 2017-05-24

Family

ID=47436293

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014550353A Expired - Fee Related JP6132853B2 (ja) 2011-12-27 2012-12-19 全身性抗炎症反応を提供する、複数のプロスタグランジン受容体で作用する化合物

Country Status (6)

Country Link
US (1) US9035071B2 (OSRAM)
EP (1) EP2797893B1 (OSRAM)
JP (1) JP6132853B2 (OSRAM)
AU (1) AU2012362724C1 (OSRAM)
CA (1) CA2862263C (OSRAM)
WO (1) WO2013101598A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8859606B2 (en) 2010-07-01 2014-10-14 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
EP2945932B1 (en) * 2013-01-21 2018-11-21 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
ITMI20132201A1 (it) * 2013-12-23 2015-06-24 Isagro Spa Processo per la sintesi regioselettiva di pirazoli
EP3886854A4 (en) 2018-11-30 2022-07-06 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
KR20230107228A (ko) 2020-11-13 2023-07-14 오노 야꾸힝 고교 가부시키가이샤 Ep4 길항약과 면역 체크포인트 저해 물질의 병용에 의한 암 치료

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
DE19924872A1 (de) 1999-05-29 2000-11-30 Dresden Arzneimittel Antikonvulsiv wirkende Pyrazolo[3,4-d][1,2,3]triazine und Verfahren zu ihrer Herstellung
US7273883B2 (en) 2000-09-14 2007-09-25 Allergan, Inc. Prostaglandin EP4 antagonist
US6511999B2 (en) 2000-09-14 2003-01-28 Allergan, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
US7217725B2 (en) 2000-09-14 2007-05-15 Allergan, Inc. Prostaglandin D2 antagonist
KR100937620B1 (ko) * 2001-11-09 2010-01-20 씨브이 쎄러퓨틱스, 인코포레이티드 Ａ２ｂ 아데노신 수용체 길항제
WO2003042183A1 (en) 2001-11-13 2003-05-22 Takeda Chemical Industries, Ltd. Process for production of pyrazole compounds
ATE386725T1 (de) * 2003-10-24 2008-03-15 Glaxo Group Ltd Heterocyclylverbindungen
CN1890241A (zh) * 2003-10-31 2007-01-03 Cv医药有限公司 A2b腺苷受体拮抗剂
US7918014B2 (en) 2005-07-13 2011-04-05 Headway Technologies, Inc. Method of manufacturing a CPP structure with enhanced GMR ratio
WO2007014054A2 (en) * 2005-07-22 2007-02-01 Glaxo Group Limted Benzenesulfonamide inhibitor of ccr2 chemokine receptor
WO2008033455A2 (en) 2006-09-13 2008-03-20 The Institutes For Pharmaceutical Discovery, Llc Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors
WO2008138876A1 (en) 2007-05-10 2008-11-20 Glaxo Group Limited Pyrazole derivatives as p2x7 modulators
JP2010248183A (ja) * 2009-03-26 2010-11-04 Takeda Chem Ind Ltd 複素環化合物
KR101906791B1 (ko) * 2010-01-27 2018-10-11 베링거 인겔하임 인터내셔날 게엠베하 Ｃｒｔｈ２ 길항제로서의 피라졸 화합물
US8492424B2 (en) * 2010-07-01 2013-07-23 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
EP2457900A1 (en) * 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
US9206164B2 (en) 2011-03-25 2015-12-08 Boehringer Ingelheim International Gmbh Pyrazole compounds as CRTH2 antagonists

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