JP2015502367A5 - - Google Patents
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- Publication number
- JP2015502367A5 JP2015502367A5 JP2014547550A JP2014547550A JP2015502367A5 JP 2015502367 A5 JP2015502367 A5 JP 2015502367A5 JP 2014547550 A JP2014547550 A JP 2014547550A JP 2014547550 A JP2014547550 A JP 2014547550A JP 2015502367 A5 JP2015502367 A5 JP 2015502367A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- phenyl
- compound
- cancer
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161576780P | 2011-12-16 | 2011-12-16 | |
| US61/576,780 | 2011-12-16 | ||
| PCT/US2012/070155 WO2013090912A1 (en) | 2011-12-16 | 2012-12-17 | Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017102107A Division JP6726640B2 (ja) | 2011-12-16 | 2017-05-23 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015502367A JP2015502367A (ja) | 2015-01-22 |
| JP2015502367A5 true JP2015502367A5 (enExample) | 2016-02-25 |
| JP6463130B2 JP6463130B2 (ja) | 2019-01-30 |
Family
ID=47436279
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014547550A Active JP6463130B2 (ja) | 2011-12-16 | 2012-12-17 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
| JP2017102107A Active JP6726640B2 (ja) | 2011-12-16 | 2017-05-23 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017102107A Active JP6726640B2 (ja) | 2011-12-16 | 2017-05-23 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9663521B2 (enExample) |
| EP (1) | EP2791142B1 (enExample) |
| JP (2) | JP6463130B2 (enExample) |
| AU (2) | AU2012353651B2 (enExample) |
| CA (1) | CA2859370C (enExample) |
| ES (1) | ES2748590T3 (enExample) |
| WO (1) | WO2013090912A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6463130B2 (ja) * | 2011-12-16 | 2019-01-30 | アメリカ合衆国 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
| SG11201700777VA (en) | 2014-08-04 | 2017-02-27 | Nuevolution As | Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases |
| US9877966B1 (en) * | 2015-08-10 | 2018-01-30 | Eugene J. Oliva | Combination therapy for the inhibition of metastasis and tumorigenesis |
| WO2018140630A1 (en) * | 2017-01-25 | 2018-08-02 | Northwestern University | Autophagy inducers for treatment of cns conditions |
| US20210186972A1 (en) * | 2018-05-15 | 2021-06-24 | The United States Of America,As Represented By The Secretary,Department Of Health And Human Services | Formulations and methods for the prevention and treatment of tumor metastasis and tumorigenesis |
| US11447479B2 (en) | 2019-12-20 | 2022-09-20 | Nuevolution A/S | Compounds active towards nuclear receptors |
| TWI872177B (zh) | 2019-12-20 | 2025-02-11 | 丹麥商紐韋盧森公司 | 對核受體具有活性之化合物 |
| JP7713953B2 (ja) | 2020-03-31 | 2025-07-28 | ヌエヴォリューション・アクティーゼルスカブ | 核内受容体に対して活性な化合物 |
| CA3174176A1 (en) | 2020-03-31 | 2021-10-07 | Sanne Schroder Glad | Compounds active towards nuclear receptors |
| WO2024026064A1 (en) * | 2022-07-29 | 2024-02-01 | The University Of North Carolina At Chapel Hill | Enhancing antimetastasis activity using targeted protein degradation |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| IL112249A (en) | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| GB9604361D0 (en) | 1996-02-29 | 1996-05-01 | Pharmacia Spa | 4-Substituted pyrrolopyrimidine compounds as tyrosine kinase inhibitors |
| US7863444B2 (en) | 1997-03-19 | 2011-01-04 | Abbott Laboratories | 4-aminopyrrolopyrimidines as kinase inhibitors |
| US6664252B2 (en) | 1999-12-02 | 2003-12-16 | Osi Pharmaceuticals, Inc. | 4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof |
| US20030114467A1 (en) | 2001-06-21 | 2003-06-19 | Shakespeare William C. | Novel pyrazolo- and pyrrolo-pyrimidines and uses thereof |
| US20090053192A1 (en) * | 2007-08-10 | 2009-02-26 | Burnham Institute For Medical Research | Tissue-nonspecific alkaline phosphatase (tnap) activators and uses thereof |
| AU2008345225A1 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| WO2011046646A2 (en) * | 2009-07-10 | 2011-04-21 | Microbiotix, Inc. | Inhibitors of filovirus entry into host cells |
| JP6463130B2 (ja) * | 2011-12-16 | 2019-01-30 | アメリカ合衆国 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
| JP6681070B2 (ja) * | 2015-11-19 | 2020-04-15 | 国立大学法人 岡山大学 | 光ファイバ装置及びセンサシステム |
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2012
- 2012-12-17 JP JP2014547550A patent/JP6463130B2/ja active Active
- 2012-12-17 CA CA2859370A patent/CA2859370C/en active Active
- 2012-12-17 WO PCT/US2012/070155 patent/WO2013090912A1/en not_active Ceased
- 2012-12-17 ES ES12806846T patent/ES2748590T3/es active Active
- 2012-12-17 EP EP12806846.7A patent/EP2791142B1/en active Active
- 2012-12-17 AU AU2012353651A patent/AU2012353651B2/en active Active
- 2012-12-17 US US14/364,759 patent/US9663521B2/en active Active
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2017
- 2017-05-23 JP JP2017102107A patent/JP6726640B2/ja active Active
- 2017-05-26 US US15/606,740 patent/US10301314B2/en active Active
- 2017-12-13 AU AU2017276258A patent/AU2017276258B2/en active Active