JP2015500840A5 - - Google Patents
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- Publication number
- JP2015500840A5 JP2015500840A5 JP2014547627A JP2014547627A JP2015500840A5 JP 2015500840 A5 JP2015500840 A5 JP 2015500840A5 JP 2014547627 A JP2014547627 A JP 2014547627A JP 2014547627 A JP2014547627 A JP 2014547627A JP 2015500840 A5 JP2015500840 A5 JP 2015500840A5
- Authority
- JP
- Japan
- Prior art keywords
- apolipoprotein
- formulation
- fixed dosage
- dosage
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000007592 Apolipoproteins Human genes 0.000 claims 48
- 108010071619 Apolipoproteins Proteins 0.000 claims 48
- 239000000203 mixture Substances 0.000 claims 37
- 238000009472 formulation Methods 0.000 claims 35
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 12
- 150000002632 lipids Chemical class 0.000 claims 10
- 102000005666 Apolipoprotein A-I Human genes 0.000 claims 6
- 108010059886 Apolipoprotein A-I Proteins 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 6
- 208000035475 disorder Diseases 0.000 claims 6
- 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 4
- ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 claims 4
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 claims 4
- NRHMKIHPTBHXPF-TUJRSCDTSA-M sodium cholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 NRHMKIHPTBHXPF-TUJRSCDTSA-M 0.000 claims 4
- 239000004094 surface-active agent Substances 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 206010002388 Angina unstable Diseases 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 208000035150 Hypercholesterolemia Diseases 0.000 claims 2
- 206010020961 Hypocholesterolaemia Diseases 0.000 claims 2
- 208000007814 Unstable Angina Diseases 0.000 claims 2
- 230000037396 body weight Effects 0.000 claims 2
- 201000004332 intermediate coronary syndrome Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 208000010125 myocardial infarction Diseases 0.000 claims 2
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 claims 2
- 230000000069 prophylactic effect Effects 0.000 claims 2
- 238000011282 treatment Methods 0.000 claims 2
- 102000015779 HDL Lipoproteins Human genes 0.000 claims 1
- 108010010234 HDL Lipoproteins Proteins 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000005022 packaging material Substances 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2011905368 | 2011-12-21 | ||
| AU2011905368A AU2011905368A0 (en) | 2011-12-21 | Dosing regime for apolipoprotein formulations | |
| PCT/AU2012/001345 WO2013090978A1 (en) | 2011-12-21 | 2012-11-02 | Dosage regime for apolipoprotein formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017045676A Division JP2017128586A (ja) | 2011-12-21 | 2017-03-10 | アポリポタンパク質製剤のための投与計画 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015500840A JP2015500840A (ja) | 2015-01-08 |
| JP2015500840A5 true JP2015500840A5 (enExample) | 2015-12-10 |
| JP6144276B2 JP6144276B2 (ja) | 2017-06-07 |
Family
ID=48667485
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014547627A Active JP6144276B2 (ja) | 2011-12-21 | 2012-11-02 | アポリポタンパク質製剤のための投与計画 |
| JP2017045676A Pending JP2017128586A (ja) | 2011-12-21 | 2017-03-10 | アポリポタンパク質製剤のための投与計画 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017045676A Pending JP2017128586A (ja) | 2011-12-21 | 2017-03-10 | アポリポタンパク質製剤のための投与計画 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20140378376A1 (enExample) |
| EP (1) | EP2793913B1 (enExample) |
| JP (2) | JP6144276B2 (enExample) |
| KR (3) | KR102766038B1 (enExample) |
| CN (2) | CN104010646A (enExample) |
| AU (1) | AU2012310259C1 (enExample) |
| BR (1) | BR112014014403A8 (enExample) |
| CA (1) | CA2857968A1 (enExample) |
| DK (1) | DK2793913T3 (enExample) |
| ES (1) | ES2955110T3 (enExample) |
| IL (1) | IL233236A0 (enExample) |
| MX (1) | MX377093B (enExample) |
| PL (1) | PL2793913T3 (enExample) |
| RU (1) | RU2014129505A (enExample) |
| SG (1) | SG11201402556RA (enExample) |
| WO (1) | WO2013090978A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9645037B2 (en) | 2011-09-28 | 2017-05-09 | Hunter Engineering Company | Method and apparatus for wheel assembly lateral force measurement |
| KR102766038B1 (ko) * | 2011-12-21 | 2025-02-12 | 시에스엘 리미티드 | 아포지질단백질 제형을 위한 용량 용법 |
| CN116196395A (zh) | 2016-11-10 | 2023-06-02 | 杰特有限公司 | 心肌梗塞的重构的高密度脂蛋白治疗 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61152632A (ja) * | 1984-12-26 | 1986-07-11 | Dai Ichi Seiyaku Co Ltd | 抗動脈硬化剤 |
| US5652339A (en) | 1993-12-31 | 1997-07-29 | Rotkreuzstiftung Zentrallaboratorium | Method of producing reconstituted lipoproteins |
| AU2002213843B2 (en) * | 2000-11-10 | 2008-02-07 | F. Hoffmann-La Roche Ltd. | Apolipoprotein analogues |
| CA2460787A1 (en) * | 2001-09-28 | 2003-04-03 | Esperion Therapeutics, Inc. | Prevention and treatment of restenosis by local administration of drug |
| JP2006507223A (ja) * | 2002-05-17 | 2006-03-02 | エスペリオン セラピューティクス，インコーポレイテッド | 脂質代謝異常疾患の治療方法 |
| EP1545576A2 (en) | 2002-07-30 | 2005-06-29 | Esperion Therapeutics Inc. | Methods of using non-human animal apoliprotein a-i protein |
| PE20050438A1 (es) * | 2003-10-20 | 2005-06-14 | Esperion Therapeutics Inc | Formulas farmaceuticas, metodos y regimenes de dosificacion para el tratamiento y la prevencion de sindromes coronarios agudos |
| AP2006003578A0 (en) * | 2003-10-20 | 2006-04-30 | Esperion Therapeutics Inc | Pharmaceutical formulations, methods and dosing regimens for the treatment and prevention of acute coronary syndromes. |
| JP2009505652A (ja) * | 2005-08-26 | 2009-02-12 | セレニス セラピューティクス ホールディング エスア | 乳酸菌においてアポリポタンパク質遺伝子生成物を生成するための組成物および方法 |
| US20090297577A1 (en) * | 2008-06-02 | 2009-12-03 | Medtronic Vascular, Inc. | Local Delivery of Apolipoproteins and Their Derivatives |
| KR102766038B1 (ko) * | 2011-12-21 | 2025-02-12 | 시에스엘 리미티드 | 아포지질단백질 제형을 위한 용량 용법 |
-
2012
- 2012-11-02 KR KR1020207009276A patent/KR102766038B1/ko active Active
- 2012-11-02 CN CN201280063210.4A patent/CN104010646A/zh active Pending
- 2012-11-02 ES ES12859136T patent/ES2955110T3/es active Active
- 2012-11-02 KR KR1020197019295A patent/KR20190084334A/ko not_active Ceased
- 2012-11-02 JP JP2014547627A patent/JP6144276B2/ja active Active
- 2012-11-02 AU AU2012310259A patent/AU2012310259C1/en active Active
- 2012-11-02 DK DK12859136.9T patent/DK2793913T3/da active
- 2012-11-02 SG SG11201402556RA patent/SG11201402556RA/en unknown
- 2012-11-02 KR KR1020147020291A patent/KR20140107536A/ko not_active Ceased
- 2012-11-02 WO PCT/AU2012/001345 patent/WO2013090978A1/en not_active Ceased
- 2012-11-02 EP EP12859136.9A patent/EP2793913B1/en active Active
- 2012-11-02 US US14/364,764 patent/US20140378376A1/en not_active Abandoned
- 2012-11-02 PL PL12859136.9T patent/PL2793913T3/pl unknown
- 2012-11-02 CA CA2857968A patent/CA2857968A1/en not_active Abandoned
- 2012-11-02 CN CN202110675512.8A patent/CN113398245A/zh active Pending
- 2012-11-02 BR BR112014014403A patent/BR112014014403A8/pt not_active Application Discontinuation
- 2012-11-02 RU RU2014129505A patent/RU2014129505A/ru unknown
- 2012-11-02 MX MX2014006589A patent/MX377093B/es active IP Right Grant
-
2014
- 2014-06-18 IL IL233236A patent/IL233236A0/en active IP Right Grant
-
2016
- 2016-02-26 US US15/054,358 patent/US20160175392A1/en not_active Abandoned
-
2017
- 2017-03-10 JP JP2017045676A patent/JP2017128586A/ja active Pending
-
2023
- 2023-08-14 US US18/449,039 patent/US20240216467A1/en not_active Abandoned
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