JP2015500831A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015500831A5 JP2015500831A5 JP2014545450A JP2014545450A JP2015500831A5 JP 2015500831 A5 JP2015500831 A5 JP 2015500831A5 JP 2014545450 A JP2014545450 A JP 2014545450A JP 2014545450 A JP2014545450 A JP 2014545450A JP 2015500831 A5 JP2015500831 A5 JP 2015500831A5
- Authority
- JP
- Japan
- Prior art keywords
- pain
- compound
- pharmaceutical composition
- phenylpropylamide
- hydroxybenzene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 13
- 208000002193 Pain Diseases 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 208000004296 neuralgia Diseases 0.000 claims 4
- 208000021722 neuropathic pain Diseases 0.000 claims 4
- 229960003742 phenol Drugs 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- 208000000094 Chronic Pain Diseases 0.000 claims 2
- 208000004454 Hyperalgesia Diseases 0.000 claims 2
- 208000001294 Nociceptive Pain Diseases 0.000 claims 2
- 208000005298 acute pain Diseases 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 208000030507 AIDS Diseases 0.000 claims 1
- 206010058019 Cancer Pain Diseases 0.000 claims 1
- 206010064012 Central pain syndrome Diseases 0.000 claims 1
- 208000032131 Diabetic Neuropathies Diseases 0.000 claims 1
- 208000035154 Hyperesthesia Diseases 0.000 claims 1
- 206010028570 Myelopathy Diseases 0.000 claims 1
- 206010033799 Paralysis Diseases 0.000 claims 1
- 206010033892 Paraplegia Diseases 0.000 claims 1
- 208000004983 Phantom Limb Diseases 0.000 claims 1
- 206010056238 Phantom pain Diseases 0.000 claims 1
- 206010065016 Post-traumatic pain Diseases 0.000 claims 1
- 206010036376 Postherpetic Neuralgia Diseases 0.000 claims 1
- 206010053552 allodynia Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 230000002085 persistent effect Effects 0.000 claims 1
- 230000002980 postoperative effect Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 206010044652 trigeminal neuralgia Diseases 0.000 claims 1
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161568219P | 2011-12-08 | 2011-12-08 | |
| US61/568,219 | 2011-12-08 | ||
| PCT/IL2012/050512 WO2013084238A1 (en) | 2011-12-08 | 2012-12-06 | Isolated stereoisomeric forms of (s) 2-n (3-o-(propan 2-ol) -1-propyl-4-hydroxybenzene) -3-phenylpropylamide |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017142137A Division JP2018021023A (ja) | 2011-12-08 | 2017-07-21 | （ｓ）２−ｎ（３−ｏ−（プロパン２−オール）−１−プロピル−４−ヒドロキシベンゼン）−３−フェニルプロピルアミドの単離された立体異性体型 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015500831A JP2015500831A (ja) | 2015-01-08 |
| JP2015500831A5 true JP2015500831A5 (enExample) | 2017-09-14 |
| JP6411893B2 JP6411893B2 (ja) | 2018-10-31 |
Family
ID=48573665
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014545450A Active JP6411893B2 (ja) | 2011-12-08 | 2012-12-06 | （ｓ）２−ｎ（３−ｏ−（プロパン２−オール）−１−プロピル−４−ヒドロキシベンゼン）−３−フェニルプロピルアミドの単離された立体異性体型 |
| JP2017142137A Pending JP2018021023A (ja) | 2011-12-08 | 2017-07-21 | （ｓ）２−ｎ（３−ｏ−（プロパン２−オール）−１−プロピル−４−ヒドロキシベンゼン）−３−フェニルプロピルアミドの単離された立体異性体型 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017142137A Pending JP2018021023A (ja) | 2011-12-08 | 2017-07-21 | （ｓ）２−ｎ（３−ｏ−（プロパン２−オール）−１−プロピル−４−ヒドロキシベンゼン）−３−フェニルプロピルアミドの単離された立体異性体型 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9381173B2 (enExample) |
| EP (1) | EP2788317B1 (enExample) |
| JP (2) | JP6411893B2 (enExample) |
| CN (1) | CN103998420B (enExample) |
| AU (1) | AU2012348529B2 (enExample) |
| CA (1) | CA2856665C (enExample) |
| DK (1) | DK2788317T3 (enExample) |
| ES (1) | ES2763946T3 (enExample) |
| HU (1) | HUE048570T2 (enExample) |
| IN (1) | IN2014MN00919A (enExample) |
| WO (1) | WO2013084238A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015173813A1 (en) * | 2014-05-14 | 2015-11-19 | Novaremed Ltd. | Pharmaceutical composition comprising stereoisomers of n-(1-(4-hydroxyphenyl)-3-(2-hydroxypropoxy)propan-2-yl)-3-phenylpropanamide for the prevention and treatment of type ii diabetes |
| KR102062268B1 (ko) | 2018-05-18 | 2020-01-03 | 한국교통대학교 산학협력단 | 발광 특성 또는 전하 전달 특성이 우수한 아지드계 가교제 |
| WO2020152226A1 (en) * | 2019-01-23 | 2020-07-30 | Novaremed Ltd. | Compounds for use in the treatment or prophylaxis of pain, inflammation and/or autoimmunity |
| EP3939578A1 (en) | 2020-07-13 | 2022-01-19 | Novaremed Ltd. | Compounds for treatment or prevention of an infection resulting from a coronavirus and/or a coronavirus-induced disease |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1546088E (pt) | 2002-10-03 | 2015-03-16 | Novaremed Ltd | Compostos para utilização no tratamento de doenças auto-imunes, de doenças imuno-alérgicas e de rejeição de órgãos ou tecidos transplantados |
| US7674829B2 (en) | 2004-03-26 | 2010-03-09 | Novaremed Limited | Compounds for the treatment of AIDS and other viral diseases |
| US20090197781A1 (en) | 2008-01-31 | 2009-08-06 | Hari Babu Sunkara | Wellbore Fluids Comprising Poly(trimethylene ether) glycol Polymers |
| GB0804213D0 (en) * | 2008-03-06 | 2008-04-16 | New Era Biotech Ltd | A method of printing or preventing pain |
| US8802734B2 (en) | 2009-09-09 | 2014-08-12 | Novaremed Limited | Method of treating or preventing pain |
| PL2475361T3 (pl) | 2009-09-09 | 2020-07-13 | Novaremed Ltd. | N-podstawione benzenopropanoamidy do stosowania w leczeniu bólu i stanu zapalnego |
| GB0916073D0 (en) | 2009-09-14 | 2009-10-28 | Cintec Int Ltd | Improvements in and relating to building anchor systems |
-
2012
- 2012-12-06 AU AU2012348529A patent/AU2012348529B2/en active Active
- 2012-12-06 CA CA2856665A patent/CA2856665C/en active Active
- 2012-12-06 DK DK12855522.4T patent/DK2788317T3/da active
- 2012-12-06 EP EP12855522.4A patent/EP2788317B1/en active Active
- 2012-12-06 ES ES12855522T patent/ES2763946T3/es active Active
- 2012-12-06 WO PCT/IL2012/050512 patent/WO2013084238A1/en not_active Ceased
- 2012-12-06 CN CN201280060570.9A patent/CN103998420B/zh active Active
- 2012-12-06 JP JP2014545450A patent/JP6411893B2/ja active Active
- 2012-12-06 HU HUE12855522A patent/HUE048570T2/hu unknown
-
2014
- 2014-05-16 IN IN919MUN2014 patent/IN2014MN00919A/en unknown
- 2014-05-30 US US14/291,901 patent/US9381173B2/en active Active
-
2017
- 2017-07-21 JP JP2017142137A patent/JP2018021023A/ja active Pending