DK2788317T3 - Isolerede stereoisomere former af (S)2-N(3-O-((S)propan-2-ol)-1-propyl-4-hydroxybenzen)-3-phenylpropylamid - Google Patents

Isolerede stereoisomere former af (S)2-N(3-O-((S)propan-2-ol)-1-propyl-4-hydroxybenzen)-3-phenylpropylamid Download PDF

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Publication number
DK2788317T3
DK2788317T3 DK12855522.4T DK12855522T DK2788317T3 DK 2788317 T3 DK2788317 T3 DK 2788317T3 DK 12855522 T DK12855522 T DK 12855522T DK 2788317 T3 DK2788317 T3 DK 2788317T3
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Denmark
Prior art keywords
phenylpropylamide
hydroxybenzene
propan
propyl
stereoisomeric forms
Prior art date
Application number
DK12855522.4T
Other languages
Danish (da)
English (en)
Inventor
Eliahu Kaplan
Original Assignee
Novaremed Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novaremed Ltd filed Critical Novaremed Ltd
Application granted granted Critical
Publication of DK2788317T3 publication Critical patent/DK2788317T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/22Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK12855522.4T 2011-12-08 2012-12-06 Isolerede stereoisomere former af (S)2-N(3-O-((S)propan-2-ol)-1-propyl-4-hydroxybenzen)-3-phenylpropylamid DK2788317T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161568219P 2011-12-08 2011-12-08
PCT/IL2012/050512 WO2013084238A1 (en) 2011-12-08 2012-12-06 Isolated stereoisomeric forms of (s) 2-n (3-o-(propan 2-ol) -1-propyl-4-hydroxybenzene) -3-phenylpropylamide

Publications (1)

Publication Number Publication Date
DK2788317T3 true DK2788317T3 (da) 2020-01-20

Family

ID=48573665

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12855522.4T DK2788317T3 (da) 2011-12-08 2012-12-06 Isolerede stereoisomere former af (S)2-N(3-O-((S)propan-2-ol)-1-propyl-4-hydroxybenzen)-3-phenylpropylamid

Country Status (11)

Country Link
US (1) US9381173B2 (enExample)
EP (1) EP2788317B1 (enExample)
JP (2) JP6411893B2 (enExample)
CN (1) CN103998420B (enExample)
AU (1) AU2012348529B2 (enExample)
CA (1) CA2856665C (enExample)
DK (1) DK2788317T3 (enExample)
ES (1) ES2763946T3 (enExample)
HU (1) HUE048570T2 (enExample)
IN (1) IN2014MN00919A (enExample)
WO (1) WO2013084238A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015173813A1 (en) * 2014-05-14 2015-11-19 Novaremed Ltd. Pharmaceutical composition comprising stereoisomers of n-(1-(4-hydroxyphenyl)-3-(2-hydroxypropoxy)propan-2-yl)-3-phenylpropanamide for the prevention and treatment of type ii diabetes
KR102062268B1 (ko) 2018-05-18 2020-01-03 한국교통대학교 산학협력단 발광 특성 또는 전하 전달 특성이 우수한 아지드계 가교제
JP7611148B2 (ja) * 2019-01-23 2025-01-09 ノヴァレメド リミテッド 疼痛、炎症および/または自己免疫の処置または予防における使用のための化合物
EP3939578A1 (en) 2020-07-13 2022-01-19 Novaremed Ltd. Compounds for treatment or prevention of an infection resulting from a coronavirus and/or a coronavirus-induced disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031129A2 (en) 2002-10-03 2004-04-15 New Era Biotech, Ltd. Compounds for use in the treatment of autoimmune diseases, immuno-allergical diseases and organ or tissue transplantation rejection
US7674829B2 (en) 2004-03-26 2010-03-09 Novaremed Limited Compounds for the treatment of AIDS and other viral diseases
US20090197781A1 (en) 2008-01-31 2009-08-06 Hari Babu Sunkara Wellbore Fluids Comprising Poly(trimethylene ether) glycol Polymers
GB0804213D0 (en) * 2008-03-06 2008-04-16 New Era Biotech Ltd A method of printing or preventing pain
US8802734B2 (en) * 2009-09-09 2014-08-12 Novaremed Limited Method of treating or preventing pain
HUE047515T2 (hu) 2009-09-09 2020-04-28 Novaremed Ltd N-Szubsztituált benzolpropánamidok fájdalom és gyulladás kezelésében történõ alkalmazásra
GB0916073D0 (en) 2009-09-14 2009-10-28 Cintec Int Ltd Improvements in and relating to building anchor systems

Also Published As

Publication number Publication date
HK1201059A1 (en) 2015-08-21
WO2013084238A1 (en) 2013-06-13
US20140275270A1 (en) 2014-09-18
EP2788317A4 (en) 2015-07-08
JP6411893B2 (ja) 2018-10-31
EP2788317B1 (en) 2019-10-02
CA2856665A1 (en) 2013-06-13
IN2014MN00919A (enExample) 2015-04-17
HUE048570T2 (hu) 2020-08-28
US9381173B2 (en) 2016-07-05
CA2856665C (en) 2019-11-12
JP2015500831A (ja) 2015-01-08
AU2012348529A1 (en) 2014-06-12
CN103998420B (zh) 2018-04-17
EP2788317A1 (en) 2014-10-15
JP2018021023A (ja) 2018-02-08
CN103998420A (zh) 2014-08-20
ES2763946T3 (es) 2020-06-01
AU2012348529B2 (en) 2017-03-30

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DK2788317T3 (da) Isolerede stereoisomere former af (S)2-N(3-O-((S)propan-2-ol)-1-propyl-4-hydroxybenzen)-3-phenylpropylamid
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