JP2015119730A5 - - Google Patents
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- JP2015119730A5 JP2015119730A5 JP2015055989A JP2015055989A JP2015119730A5 JP 2015119730 A5 JP2015119730 A5 JP 2015119730A5 JP 2015055989 A JP2015055989 A JP 2015055989A JP 2015055989 A JP2015055989 A JP 2015055989A JP 2015119730 A5 JP2015119730 A5 JP 2015119730A5
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- Prior art keywords
- virus
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 241000700605 Viruses Species 0.000 claims 16
- 238000000034 method Methods 0.000 claims 16
- 241000712431 Influenza A virus Species 0.000 claims 11
- 239000002773 nucleotide Substances 0.000 claims 10
- 125000003729 nucleotide group Chemical group 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 7
- 229960005486 vaccine Drugs 0.000 claims 7
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 230000003612 virological effect Effects 0.000 claims 5
- 238000012258 culturing Methods 0.000 claims 2
- 206010022000 influenza Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000001464 adherent effect Effects 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 210000000991 chicken egg Anatomy 0.000 claims 1
- 230000000415 inactivating effect Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 210000003501 vero cell Anatomy 0.000 claims 1
- 210000002845 virion Anatomy 0.000 claims 1
- 239000000277 virosome Substances 0.000 claims 1
- 229940126581 whole-virion vaccine Drugs 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261605922P | 2012-03-02 | 2012-03-02 | |
| US61/605,922 | 2012-03-02 | ||
| US201261685766P | 2012-03-23 | 2012-03-23 | |
| US61/685,766 | 2012-03-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013548864A Division JP6054883B2 (ja) | 2012-03-02 | 2013-03-02 | インフルエンザウイルスの再集合 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015119730A JP2015119730A (ja) | 2015-07-02 |
| JP2015119730A5 true JP2015119730A5 (enExample) | 2016-10-13 |
| JP6279503B2 JP6279503B2 (ja) | 2018-02-14 |
Family
ID=47997362
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013548864A Active JP6054883B2 (ja) | 2012-03-02 | 2013-03-02 | インフルエンザウイルスの再集合 |
| JP2015055989A Active JP6279503B2 (ja) | 2012-03-02 | 2015-03-19 | インフルエンザウイルスの再集合 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013548864A Active JP6054883B2 (ja) | 2012-03-02 | 2013-03-02 | インフルエンザウイルスの再集合 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US9422528B2 (enExample) |
| EP (1) | EP2820126B1 (enExample) |
| JP (2) | JP6054883B2 (enExample) |
| CN (1) | CN103608453B (enExample) |
| AU (1) | AU2013205478B9 (enExample) |
| CA (1) | CA2813723A1 (enExample) |
| ES (1) | ES2628301T3 (enExample) |
| WO (1) | WO2013087945A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| JP2014527799A (ja) | 2011-08-26 | 2014-10-23 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | 変異型ｐｂ２遺伝子セグメントを有する弱毒化生ワクチンとしてのインフルエンザウイルス |
| US20140274806A1 (en) | 2013-03-15 | 2014-09-18 | Synthetic Genomics Vaccines | Influenza virus reassortment |
| CN105142667A (zh) * | 2013-01-23 | 2015-12-09 | 诺华股份有限公司 | 流感病毒重配 |
| HK1222882A1 (zh) * | 2013-06-06 | 2017-07-14 | Novartis Ag | 流感病毒重配 |
| WO2015196150A2 (en) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
| RU2605317C1 (ru) * | 2015-06-04 | 2016-12-20 | Федеральное государственное автономное образовательное учреждение высшего образования "Новосибирский национальный исследовательский государственный университет" (Новосибирский государственный университет, НГУ) | АДАПТИРОВАННЫЕ ПАНДЕМИЧЕСКИЕ ШТАММЫ ВИРУСА ГРИППА A/Tomsk/273/2010-MA1(H1N1pdm09), A/Tomsk/273/2010-MA2(H1N1pdm09) И A/Tomsk/273/2010-MA3(H1N1pdm09) ДЛЯ ОЦЕНКИ ДЕЙСТВИЯ ПРОТИВОВИРУСНЫХ ПРЕПАРАТОВ (ВАРИАНТЫ) |
| EP3313439A2 (en) | 2015-06-26 | 2018-05-02 | Seqirus UK Limited | Antigenically matched influenza vaccines |
| KR102576962B1 (ko) | 2015-07-07 | 2023-09-11 | 세퀴러스 유케이 리미티드 | 인플루엔자 효능 검정 |
| JP2018530314A (ja) * | 2015-08-28 | 2018-10-18 | ウィスコンシン アルムニ リサーチ ファンデイション | ウイルス様粒子からの感染性インフルエンザウイルスの生成 |
| JP2019510481A (ja) | 2016-02-19 | 2019-04-18 | ウィスコンシン アルムニ リサーチ ファンデイション | ワクチン開発のための改善されたｂ型インフルエンザウイルス複製 |
| KR102477492B1 (ko) | 2016-07-15 | 2022-12-13 | 잇판사이단호진한다이비세이부쯔뵤우겐큐우카이 | 리소턴트 인플루엔자 바이러스 작출 방법 |
| KR20200040750A (ko) * | 2017-08-28 | 2020-04-20 | 잇판사이단호진한다이비세이부쯔뵤우겐큐우카이 | 리소턴트 인플루엔자 바이러스의 단계적 작출 방법 |
| EP3700562A1 (en) | 2017-10-25 | 2020-09-02 | Wisconsin Alumni Research Foundation (WARF) | Recombinant influenza viruses with stabilized ha for replication in eggs |
| SG11202003793WA (en) | 2017-10-30 | 2020-05-28 | Baxalta GmbH | Environmentally compatible detergents for inactivation of lipid-enveloped viruses |
| JP7783047B2 (ja) | 2018-08-07 | 2025-12-09 | ウィスコンシン アルムニ リサーチ ファンデイション | 組換えの生物学的に封じ込められたフィロウイルスワクチン |
| EP3840780A1 (en) | 2018-08-20 | 2021-06-30 | Wisconsin Alumni Research Foundation | Vectors for eliciting immune responses to non-dominant epitopes in the hemagglutinin (ha) protein |
| US11851648B2 (en) | 2019-02-08 | 2023-12-26 | Wisconsin Alumni Research Foundation (Warf) | Humanized cell line |
| WO2020223699A1 (en) | 2019-05-01 | 2020-11-05 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza virus replication for vaccine development |
| WO2021041624A2 (en) | 2019-08-27 | 2021-03-04 | Yoshihiro Kawaoka | Recombinant influenza viruses with stabilized ha for replication in eggs |
| JP2023511444A (ja) | 2020-01-24 | 2023-03-17 | ウィスコンシン アルムニ リサーチ ファンデイション | 安定化されたｎａを有する組換えインフルエンザウイルス |
| US12290562B2 (en) | 2020-03-25 | 2025-05-06 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
| WO2021221338A1 (ko) * | 2020-04-29 | 2021-11-04 | 에스케이바이오사이언스(주) | 일회용 배양 공정 시스템을 이용한 인플루엔자 바이러스 생산 방법 및 인플루엔자 바이러스 항원 정제 조건 신속 확인 시험 |
| US11694876B2 (en) | 2021-12-08 | 2023-07-04 | Applied Materials, Inc. | Apparatus and method for delivering a plurality of waveform signals during plasma processing |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2017507C (en) | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
| WO1995011700A1 (en) | 1993-10-29 | 1995-05-04 | Pharmos Corp. | Submicron emulsions as vaccine adjuvants |
| DE19612967A1 (de) | 1996-04-01 | 1997-10-02 | Behringwerke Ag | Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren |
| DE19612966B4 (de) * | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren |
| TW570803B (en) | 1997-04-09 | 2004-01-11 | Duphar Int Res | Influenza vaccine |
| US6080725A (en) | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
| CA2334857C (en) | 1998-06-12 | 2012-03-20 | Mount Sinai School Of Medicine Of The City University Of New York | Interferon inducing genetically engineered attenuated viruses |
| WO2001021151A1 (en) | 1999-09-24 | 2001-03-29 | Smithkline Beecham Biologicals S.A. | Intranasal influenza virus vaccine |
| JP4698112B2 (ja) | 2000-03-03 | 2011-06-08 | 一般財団法人化学及血清療法研究所 | 無血清培養かつ浮遊培養可能な細胞及び当該細胞を用いたワクチン用ウイルスの製造法 |
| GB0024089D0 (en) | 2000-10-02 | 2000-11-15 | Smithkline Beecham Biolog | Novel compounds |
| EP1361889A1 (en) | 2001-02-23 | 2003-11-19 | GlaxoSmithKline Biologicals S.A. | Novel vaccine |
| EP2281573A3 (en) | 2001-02-23 | 2011-12-07 | GlaxoSmithKline Biologicals s.a. | Influenza vaccine formulations for intradermal delivery |
| MY134424A (en) | 2001-05-30 | 2007-12-31 | Saechsisches Serumwerk | Stable influenza virus preparations with low or no amount of thiomersal |
| US8475806B2 (en) * | 2003-05-28 | 2013-07-02 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines and gene therapy |
| EP1742659B1 (en) | 2004-04-05 | 2013-03-13 | Pah Usa 15 Llc | Microfluidized oil-in-water emulsions and vaccine compositions |
| WO2005113756A1 (en) | 2004-05-14 | 2005-12-01 | Glaxosmithkline Biologicals S.A. | Method |
| NZ551640A (en) | 2004-05-20 | 2010-05-28 | Id Biomedical Corp | Process for the production of an influenza vaccine |
| EP1831353B1 (en) | 2004-12-23 | 2012-02-29 | MedImmune, LLC | Non-tumorigenic mdck cell line for propagating viruses |
| US7691368B2 (en) | 2005-04-15 | 2010-04-06 | Merial Limited | Vaccine formulations |
| EP1917361A4 (en) | 2005-06-21 | 2009-07-29 | Medimmune Vaccines Inc | METHODS AND COMPOSITIONS FOR EXPRESSING NEGATIVE SENSE RNA VIRUS IN CANINE CELLS |
| US8703095B2 (en) | 2005-07-07 | 2014-04-22 | Sanofi Pasteur S.A. | Immuno-adjuvant emulsion |
| NZ567817A (en) | 2005-11-01 | 2012-01-12 | Novartis Vaccines & Diagnostic | Cell-derived viral vaccines with low levels of residual cell DNA by beta-propiolactone treatment |
| NZ568210A (en) | 2005-11-04 | 2012-12-21 | Novartis Vaccines & Diagnostic | Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines |
| FR2896162B1 (fr) | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
| AU2007245192B2 (en) * | 2006-03-31 | 2012-04-12 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
| DK2016194T3 (en) | 2006-04-19 | 2015-06-15 | Medimmune Llc | METHODS AND COMPOSITIONS FOR EXPRESSION OF VIRAL NEGATIVE SENSE RNA IN DOG CELLS |
| CN101522218B (zh) | 2006-10-12 | 2012-09-26 | 葛兰素史密丝克莱恩生物有限公司 | 包含水包油乳液佐剂的疫苗 |
| ES2480491T3 (es) | 2006-12-06 | 2014-07-28 | Novartis Ag | Vacunas incluyendo antígeno de cuatro cepas de virus de la gripe |
| EP2045323A1 (en) | 2007-10-05 | 2009-04-08 | Avir Green Hills Biotechnology Research Development Trade Ag | Linear expression constructs for production of influenza virus particles |
| AU2009333208A1 (en) * | 2008-12-16 | 2010-07-08 | Baxter Healthcare Sa | Production of influenza vaccines |
| EP2233152A1 (en) * | 2009-03-24 | 2010-09-29 | Avir Green Hills Biotechnology Research Development Trade Ag | High growth reassortant influenza A virus |
| JP2013500712A (ja) | 2009-07-31 | 2013-01-10 | ノバルティス アーゲー | 逆遺伝学系 |
| JP2013507990A (ja) * | 2009-10-26 | 2013-03-07 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス |
| JP2014527799A (ja) * | 2011-08-26 | 2014-10-23 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | 変異型ｐｂ２遺伝子セグメントを有する弱毒化生ワクチンとしてのインフルエンザウイルス |
-
2013
- 2013-03-02 EP EP13712156.2A patent/EP2820126B1/en active Active
- 2013-03-02 WO PCT/EP2013/054227 patent/WO2013087945A2/en not_active Ceased
- 2013-03-02 CA CA2813723A patent/CA2813723A1/en not_active Abandoned
- 2013-03-02 JP JP2013548864A patent/JP6054883B2/ja active Active
- 2013-03-02 CN CN201380000396.3A patent/CN103608453B/zh active Active
- 2013-03-02 AU AU2013205478A patent/AU2013205478B9/en active Active
- 2013-03-02 ES ES13712156.2T patent/ES2628301T3/es active Active
- 2013-06-03 US US13/909,013 patent/US9422528B2/en active Active
-
2015
- 2015-03-19 JP JP2015055989A patent/JP6279503B2/ja active Active
-
2016
- 2016-07-14 US US15/210,485 patent/US10245312B2/en active Active
-
2019
- 2019-02-11 US US16/272,018 patent/US20200000909A1/en not_active Abandoned
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