JP2015034182A5 - - Google Patents

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Publication number
JP2015034182A5
JP2015034182A5 JP2014232639A JP2014232639A JP2015034182A5 JP 2015034182 A5 JP2015034182 A5 JP 2015034182A5 JP 2014232639 A JP2014232639 A JP 2014232639A JP 2014232639 A JP2014232639 A JP 2014232639A JP 2015034182 A5 JP2015034182 A5 JP 2015034182A5
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
integer
mol
polyorthoester
Prior art date
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JP2014232639A
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English (en)
Japanese (ja)
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JP6057972B2 (ja
JP2015034182A (ja
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Priority claimed from US10/953,841 external-priority patent/US20050042194A1/en
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Publication of JP2015034182A publication Critical patent/JP2015034182A/ja
Publication of JP2015034182A5 publication Critical patent/JP2015034182A5/ja
Application granted granted Critical
Publication of JP6057972B2 publication Critical patent/JP6057972B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2014232639A 2004-09-28 2014-11-17 半固体送達賦形剤および薬学的組成物 Expired - Lifetime JP6057972B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/953,841 2004-09-28
US10/953,841 US20050042194A1 (en) 2000-05-11 2004-09-28 Semi-solid delivery vehicle and pharmaceutical compositions

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2012045876A Division JP2012107064A (ja) 2004-09-28 2012-03-01 半固体送達賦形剤および薬学的組成物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016203588A Division JP2017008113A (ja) 2004-09-28 2016-10-17 半固体送達賦形剤および薬学的組成物

Publications (3)

Publication Number Publication Date
JP2015034182A JP2015034182A (ja) 2015-02-19
JP2015034182A5 true JP2015034182A5 (https=) 2015-04-09
JP6057972B2 JP6057972B2 (ja) 2017-01-11

Family

ID=36119607

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2007533786A Withdrawn JP2008514646A (ja) 2004-09-28 2005-09-27 半固体送達賦形剤および薬学的組成物
JP2012045876A Withdrawn JP2012107064A (ja) 2004-09-28 2012-03-01 半固体送達賦形剤および薬学的組成物
JP2014232639A Expired - Lifetime JP6057972B2 (ja) 2004-09-28 2014-11-17 半固体送達賦形剤および薬学的組成物
JP2016203588A Pending JP2017008113A (ja) 2004-09-28 2016-10-17 半固体送達賦形剤および薬学的組成物

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2007533786A Withdrawn JP2008514646A (ja) 2004-09-28 2005-09-27 半固体送達賦形剤および薬学的組成物
JP2012045876A Withdrawn JP2012107064A (ja) 2004-09-28 2012-03-01 半固体送達賦形剤および薬学的組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016203588A Pending JP2017008113A (ja) 2004-09-28 2016-10-17 半固体送達賦形剤および薬学的組成物

Country Status (10)

Country Link
US (10) US20050042194A1 (https=)
EP (4) EP3424492B1 (https=)
JP (4) JP2008514646A (https=)
KR (1) KR20070083851A (https=)
CN (1) CN101052376A (https=)
AU (1) AU2005289425A1 (https=)
CA (1) CA2579297A1 (https=)
ES (1) ES2529574T3 (https=)
TW (1) TWI407966B (https=)
WO (1) WO2006037116A2 (https=)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050042194A1 (en) 2000-05-11 2005-02-24 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
ATE482695T1 (de) 2002-12-13 2010-10-15 Durect Corp Orale darreichungsform mit flüssigen hochviskosen trägersystemen
AU2005287175B2 (en) * 2004-09-17 2011-12-01 Durect Corporation Sustained local anesthetic composition containing preferably a sugar ester such as SAIB
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US20070264338A1 (en) * 2006-05-12 2007-11-15 Shah Devang T Base-stabilized polyorthoester formulations
US20070265329A1 (en) * 2006-05-12 2007-11-15 Devang Shah T Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
US20070264339A1 (en) * 2006-05-12 2007-11-15 Ap Pharma, Inc. Base-stabilized polyorthoester formulations
FR2901702A1 (fr) * 2006-05-31 2007-12-07 Galderma Res & Dev S N C Snc Utilisation de granisetron pour le traitement de sous-types de la rosacee, et compositions pharmaceutiques
WO2008005371A2 (en) * 2006-06-29 2008-01-10 Medtronic, Inc. Poly(orthoester) polymers, and methods of making and using same
EP1917971A1 (en) * 2006-10-27 2008-05-07 Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) Substained release formulations comprising very low molecular weight polymers
US8337883B2 (en) 2006-11-03 2012-12-25 Durect Corporation Transdermal delivery systems
EP2219622A1 (en) 2007-12-06 2010-08-25 Durect Corporation Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition
US8940315B2 (en) * 2008-04-18 2015-01-27 Medtronic, Inc. Benzodiazepine formulation in a polyorthoester carrier
US8956642B2 (en) * 2008-04-18 2015-02-17 Medtronic, Inc. Bupivacaine formulation in a polyorthoester carrier
ES2563061T3 (es) * 2008-04-28 2016-03-10 Zogenix, Inc. Nuevas formulaciones para el tratamiento de la migraña
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
BRPI0916761A2 (pt) * 2008-07-17 2018-02-14 Ap Pharma formulações analgésicas injetáveis de ação prolongada para animais
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
MX2011006265A (es) * 2008-12-11 2012-06-28 A P Pharma Inc Metodos para mejorar la estabilidad de poliortoesteres y sus formulaciones.
TWI372057B (en) * 2008-12-11 2012-09-11 Dev Center Biotechnology Sustained release implant for granisetron
US9849180B2 (en) 2014-09-15 2017-12-26 Hui Rong Shen Long-acting semi-solid lipid formulations
US10220093B2 (en) 2013-02-28 2019-03-05 Mira Pharma Corporation Long-acting semi-solid lipid formulations
TW201521769A (zh) 2013-03-15 2015-06-16 Durect Corp 具有流變改質劑以減少溶解變異性之組成物
US9592227B2 (en) 2013-03-15 2017-03-14 Heron Therapeutics, Inc. Compositions of a polyorthoester and an aprotic solvent
US20140323517A1 (en) * 2013-04-30 2014-10-30 Heron Therapeutics, Inc. Compositions and methods for injection of a biodegradable polymer-based delivery system
CA2924233C (en) 2013-10-07 2018-10-23 Teikoku Pharma Usa, Inc. Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions
KR101948779B1 (ko) 2013-10-07 2019-05-21 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치 및 이의 사용 방법
CA2924236C (en) 2013-10-07 2020-01-07 Teikoku Pharma Usa, Inc. Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
DK3134070T3 (da) 2014-04-21 2020-12-21 Heron Therapeutics Inc Sammensætninger af en polyorthoester og en organisk syre-excipiens
US9801945B2 (en) 2014-04-21 2017-10-31 Heron Therapeutics, Inc. Long-acting polymeric delivery systems
WO2018048460A1 (en) 2014-04-21 2018-03-15 Heron Therapeutics, Inc. A pharmaceutical composition comprising a delivery system, an amide-type local anesthetic, and meloxicam
PT3134068T (pt) 2014-04-21 2021-10-18 Heron Therapeutics Inc Sistemas de libertação poliméricos de longa duração
SG11201811760VA (en) 2016-07-06 2019-01-30 Durect Corp Oral dosage form with drug composition, barrier layer and drug layer
BR112019006955A2 (pt) 2016-10-31 2019-07-02 Teikoku Pharma Usa Inc métodos de controle da dor usando dispositivos de distribuição transdérmica de dexmedetomidina
CN107789628B (zh) * 2016-12-29 2021-07-23 天津键凯科技有限公司 一种聚乙二醇和局部麻醉药的结合物在非麻醉镇痛中的应用
US10561606B2 (en) 2017-12-06 2020-02-18 Mira Pharma Corporation Injectable long-acting local anesthetic semi-solid gel formulations
US11426418B2 (en) 2017-12-06 2022-08-30 Mira Pharma Corporation Injectable long-acting semi-solid gel formulations
US11162850B2 (en) 2019-04-25 2021-11-02 Measurement Specialties, Inc. Sensor assemblies with integrated electrical connections and diaphragm overload protection
CN115666621A (zh) 2020-01-13 2023-01-31 度勒科特公司 具有减少的杂质的持续释放药物递送系统及相关方法
CN113980254A (zh) * 2020-07-10 2022-01-28 南京泛太化工医药研究所 一种具有酸敏感降解、温敏性质的系列聚合物及其载药组合物
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods
CA3231500A1 (en) * 2021-09-09 2023-03-16 Xeris Pharmaceuticals, Inc. Injectable high concentration pharmaceutical formulations and methods of manufacturing and use thereof
CN114366711A (zh) * 2021-12-09 2022-04-19 安徽大学 原酸酯混溶物药用辅料、制备方法、包含该辅料的局部缓释给药制剂
WO2023137659A1 (zh) * 2022-01-20 2023-07-27 南京泛太化工医药研究所 一种具有酸敏感降解、温敏性质的系列聚合物及其载药组合物

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179497A (en) * 1973-12-17 1979-12-18 Merck & Co., Inc. Solid state ophthalmic medication
US4093709A (en) * 1975-01-28 1978-06-06 Alza Corporation Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates)
US4131648A (en) * 1975-01-28 1978-12-26 Alza Corporation Structured orthoester and orthocarbonate drug delivery devices
US4180646A (en) * 1975-01-28 1979-12-25 Alza Corporation Novel orthoester polymers and orthocarbonate polymers
NL188266C (nl) * 1975-07-29 1992-05-18 Merck & Co Inc Werkwijze ter bereiding van een oogheelkundig inplantaat.
US4098709A (en) * 1975-12-11 1978-07-04 Rohm And Haas Company Polymeric antioxidant viscosity index improvers
US4079038A (en) * 1976-03-05 1978-03-14 Alza Corporation Poly(carbonates)
US4304767A (en) * 1980-05-15 1981-12-08 Sri International Polymers of di- (and higher functionality) ketene acetals and polyols
US4322323A (en) * 1980-12-01 1982-03-30 Alza Corporation Erodible device comprising surfactant for modifying the rate of erosion of the device
PT75625B (en) 1981-10-08 1985-12-09 Merck & Co Inc Process for preparing biosoluble ocular insert
US4532335A (en) * 1983-03-07 1985-07-30 Sri International Preparation of ketene acetals by rearrangement of allyl and substituted allyl acetals
GB8416234D0 (en) * 1984-06-26 1984-08-01 Ici Plc Biodegradable amphipathic copolymers
US4549010A (en) * 1984-06-27 1985-10-22 Merck & Co., Inc. Bioerodible poly(ortho ester) thermoplastic elastomer from diketene diacetal
US4946931A (en) * 1989-06-14 1990-08-07 Pharmaceutical Delivery Systems, Inc. Polymers containing carboxy-ortho ester and ortho ester linkages
PL166267B1 (pl) * 1989-11-28 1995-04-28 Syntex Inc Sposób wytwarzania nowych zwiazków trójpierscieniowych PL PL PL PL
NZ239370A (en) * 1990-08-22 1994-04-27 Merck & Co Inc Bioerodible implantable controlled release dosage form comprising a poly(ortho ester) or a polyacetal with an active agent incorporated into the chain backbone
IE920040A1 (en) 1991-01-09 1992-07-15 Alza Corp Bioerodible devices and compositions for diffusional release¹of agents
US5929059A (en) * 1991-01-19 1999-07-27 Smithkline Beecham P.L.C. Pharmaceutical compositions containing granisetron and dexamethasone
US5211951A (en) * 1991-07-24 1993-05-18 Merck & Co., Inc. Process for the manufacture of bioerodible poly (orthoester)s and polyacetals
MX9301821A (es) 1992-03-30 1994-03-31 Alza Corp Sistema de matriz polimerica biodegradable regulador de degradacion y metodo de tratamiento del mismo.
WO1993019739A1 (en) * 1992-03-30 1993-10-14 Alza Corporation Viscous suspensions of controlled-release drug particles
AU4406793A (en) * 1992-06-04 1993-12-30 Clover Consolidated, Limited Water-soluble polymeric carriers for drug delivery
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5989586A (en) * 1992-10-05 1999-11-23 Cygnus, Inc. Two-phase matrix for sustained release drug delivery device
EP0676952B1 (en) 1992-12-29 2000-07-12 Insite Vision Incorporated Bioerodible controlled delivery system
MY113268A (en) * 1992-12-29 2002-01-31 Insite Vision Incorporated Plasticized bioerodible controlled delivery system
JP4259610B2 (ja) * 1994-04-08 2009-04-30 キューエルティー・ユーエスエイ・インコーポレーテッド 液体デリバリー組成物
GB9412995D0 (en) * 1994-06-28 1994-10-26 Prendergast Kenneth F Safety enhancing pharmaceutical compositions of an active indazole
US6007845A (en) * 1994-07-22 1999-12-28 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
US5607686A (en) * 1994-11-22 1997-03-04 United States Surgical Corporation Polymeric composition
BR9706960A (pt) 1996-01-05 1999-12-28 Advanced Polymer Systems Inc Polìmeros com estado fìsico e condição de bioerosão controlados
US5968543A (en) * 1996-01-05 1999-10-19 Advanced Polymer Systems, Inc. Polymers with controlled physical state and bioerodibility
US5690059A (en) * 1996-04-16 1997-11-25 Woods; Jeff Training collar
FR2748364B1 (fr) * 1996-05-09 1998-07-31 Kuhn Sa Broyeur de vegetaux perfectionne quant a sa faculte d'adaptation au relief du sol
EP0906315A1 (en) 1996-06-21 1999-04-07 MERCK SHARP & DOHME LTD. Spiro-piperidine derivatives and their use as therapeutic agents
US6046187A (en) * 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
PT839525E (pt) * 1996-10-31 2004-10-29 Takeda Chemical Industries Ltd Preparacao de libertacao prolongada
US5993856A (en) * 1997-01-24 1999-11-30 Femmepharma Pharmaceutical preparations and methods for their administration
WO1998053815A1 (en) * 1997-05-30 1998-12-03 Minnesota Mining And Manufacturing Company Transdermal drug delivery device for the delivery of tropisetron or granisetron
US6103266A (en) * 1998-04-22 2000-08-15 Tapolsky; Gilles H. Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues
US5939453A (en) 1998-06-04 1999-08-17 Advanced Polymer Systems, Inc. PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
GB9813576D0 (en) 1998-06-24 1998-08-19 Merck Sharp & Dohme Therapeutic agents
US6143314A (en) * 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
US6613355B2 (en) * 2000-05-11 2003-09-02 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
WO2001085139A2 (en) * 2000-05-11 2001-11-15 Advanced Polymer Systems, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
US20050042194A1 (en) 2000-05-11 2005-02-24 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
ES2228906T3 (es) 2000-07-18 2005-04-16 Leo Pharma A/S Inhibidores de la metaloproteinasas de matriz.
KR100446101B1 (ko) * 2000-12-07 2004-08-30 주식회사 삼양사 수난용성 약물의 서방성 제형 조성물
US20020176844A1 (en) * 2001-05-11 2002-11-28 Ng Steven Y. Bioerodible polyorthoesters containing hydrogen bonding groups
US6590059B2 (en) * 2001-05-11 2003-07-08 Ap Pharma, Inc. Bioerodible polyorthoesters from dioxolane-based diketene acetals
FR2826280B1 (fr) 2001-06-20 2005-03-04 Ceva Sante Animale Composition semi-solide injectable biodegradable assurant un profil de liberation particulier
US6524606B1 (en) * 2001-11-16 2003-02-25 Ap Pharma, Inc. Bioerodible polyorthoesters containing amine groups
CN1684663A (zh) * 2002-07-31 2005-10-19 阿尔萨公司 可注射的多模式聚合物储库组合物以及其用途
AU2002359397B2 (en) * 2002-07-31 2009-01-29 Durect Corporation Injectable depot compositions and uses thereof
RU2355385C2 (ru) * 2002-11-06 2009-05-20 Алза Корпорейшн Композиции пролонгированного действия с контролируемым высвобождением
US7045589B2 (en) * 2002-11-15 2006-05-16 A.P. Pharma, Inc. Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
US20050096365A1 (en) * 2003-11-03 2005-05-05 David Fikstad Pharmaceutical compositions with synchronized solubilizer release
JP2008534747A (ja) * 2005-03-31 2008-08-28 エーピー ファーマ， インコーポレイテッド Ｐｅｇ−ポリアセタールグラフトコポリマーおよびｐｅｇ−ポリアセタール−ｐｏｅグラフトコポリマーならびに医薬組成物
KR20070122522A (ko) * 2005-03-31 2007-12-31 에이피 파마, 인코포레이티드 Ｐｅｇ-폴리(오르토 에스테르) 그라프트 공중합체 및 약학조성물
US20070264339A1 (en) 2006-05-12 2007-11-15 Ap Pharma, Inc. Base-stabilized polyorthoester formulations

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