JP2016531895A5 - - Google Patents
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- Publication number
- JP2016531895A5 JP2016531895A5 JP2016520004A JP2016520004A JP2016531895A5 JP 2016531895 A5 JP2016531895 A5 JP 2016531895A5 JP 2016520004 A JP2016520004 A JP 2016520004A JP 2016520004 A JP2016520004 A JP 2016520004A JP 2016531895 A5 JP2016531895 A5 JP 2016531895A5
- Authority
- JP
- Japan
- Prior art keywords
- conjugate
- conjugate according
- patient
- polyethylene glycol
- peg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361887111P | 2013-10-04 | 2013-10-04 | |
| US61/887,111 | 2013-10-04 | ||
| PCT/US2014/059146 WO2015051307A1 (en) | 2013-10-04 | 2014-10-03 | Slow-release conjugates of sn-38 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019010029A Division JP6842479B2 (ja) | 2013-10-04 | 2019-01-24 | Ｓｎ−３８の徐放性コンジュゲート |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531895A JP2016531895A (ja) | 2016-10-13 |
| JP2016531895A5 true JP2016531895A5 (https=) | 2017-11-09 |
| JP6473145B2 JP6473145B2 (ja) | 2019-02-20 |
Family
ID=51871275
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016520004A Active JP6473145B2 (ja) | 2013-10-04 | 2014-10-03 | Ｓｎ−３８の徐放性コンジュゲート |
| JP2019010029A Active JP6842479B2 (ja) | 2013-10-04 | 2019-01-24 | Ｓｎ−３８の徐放性コンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019010029A Active JP6842479B2 (ja) | 2013-10-04 | 2019-01-24 | Ｓｎ−３８の徐放性コンジュゲート |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10016411B2 (https=) |
| EP (1) | EP3052101B1 (https=) |
| JP (2) | JP6473145B2 (https=) |
| KR (1) | KR102320753B1 (https=) |
| CN (1) | CN106061483B (https=) |
| AU (2) | AU2014331591B2 (https=) |
| BR (1) | BR112016007410B1 (https=) |
| CA (1) | CA2925132C (https=) |
| DK (1) | DK3052101T3 (https=) |
| ES (1) | ES2759905T3 (https=) |
| MX (1) | MX371201B (https=) |
| SG (2) | SG11201602258WA (https=) |
| TW (1) | TWI716342B (https=) |
| WO (1) | WO2015051307A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX371201B (es) * | 2013-10-04 | 2020-01-22 | Prolynx Llc | Conjugados de liberación lenta de sn-38. |
| CN107375288B (zh) * | 2016-05-16 | 2019-08-23 | 博瑞生物医药（苏州）股份有限公司 | 多臂的聚合靶向抗癌偶联物 |
| KR102279429B1 (ko) | 2017-04-21 | 2021-07-20 | 브라이트제네 바이오-메디컬 테크놀로지 코., 엘티디. | 멀티 암 표적 항암 콘쥬게이트 |
| MX2020007442A (es) * | 2018-01-12 | 2020-09-14 | Prolynx Llc | Protocolo para minimizar la toxicidad de dosificaciones de combinacion y agente formador de imagen para verificacion. |
| CA3112778A1 (en) | 2018-09-17 | 2020-03-26 | The Children's Hospital Of Philadelphia | Polymer-based macromolecular prodrugs |
| CN119970617A (zh) * | 2019-04-05 | 2025-05-13 | 普罗林科斯有限责任公司 | 改良偶联接头 |
| CA3151529A1 (en) * | 2019-08-28 | 2021-03-04 | Prolynx Llc | Conjugated inhibitors of dna damage response |
| IL301558A (en) | 2020-09-28 | 2023-05-01 | Fundacio Inst De Recerca Biomedica Irb Barcelona | Peptidic conjugates of sn38 useful in the treatment of cancer |
| US11976196B2 (en) * | 2021-04-14 | 2024-05-07 | Cambridge Crops, Inc. | Silk packaging applications |
| WO2023186822A1 (en) | 2022-03-28 | 2023-10-05 | Hospital Sant Joan De Deu | Peptidic water-soluble delivery system of anticancer drugs |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6011042A (en) * | 1997-10-10 | 2000-01-04 | Enzon, Inc. | Acyl polymeric derivatives of aromatic hydroxyl-containing compounds |
| JP2005537266A (ja) * | 2002-07-12 | 2005-12-08 | バイオマリン ファーマシューティカル インコーポレイテッド | 加水分解性活性物質であるバイオポリマーコンジュゲートを作製するためのイソシアネートリンカーの使用 |
| AU2003280592B2 (en) | 2002-10-31 | 2008-12-18 | Nippon Kayaku Kabushiki Kaisha | High-molecular weight derivatives of camptothecins |
| US20040247624A1 (en) * | 2003-06-05 | 2004-12-09 | Unger Evan Charles | Methods of making pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
| CA2537336C (en) | 2003-09-17 | 2013-02-26 | Nektar Therapeutics Al, Corporation | Multi-arm polymer prodrugs |
| US7462627B2 (en) | 2006-02-09 | 2008-12-09 | Enzon Pharmaceuticals, Inc. | Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers |
| JP2010503708A (ja) * | 2006-09-15 | 2010-02-04 | エンゾン ファーマスーティカルズ インコーポレイテッド | 多官能性リンカーを含む標的化ポリマープロドラッグ |
| KR20110075029A (ko) * | 2008-10-21 | 2011-07-05 | 엔즌 파마슈티칼스, 인코포레이티드 | 7-에틸-10-하이드록시캄토테신의 다중-암 고분자 컨쥬게이트로 신경모세포종의 치료 |
| AU2009316749A1 (en) | 2008-11-18 | 2011-06-30 | Baxter Healthcare S.A. | Methods of determining polydispersity and/or molecular weight distribution of a polyethylene glycol sample |
| AU2010254013A1 (en) | 2009-05-28 | 2011-11-24 | Mersana Therapeutics, Inc. | Polyal drug conjugates comprising variable rate-releasing linkers |
| PT2501413T (pt) * | 2009-11-18 | 2019-07-10 | Nektar Therapeutics | Formas de sal de ácido de conjugados de polímero-fármaco |
| US8703907B2 (en) * | 2010-05-05 | 2014-04-22 | Prolynx Llc | Controlled drug release from dendrimers |
| ES2584381T3 (es) * | 2010-05-05 | 2016-09-27 | Prolynx Llc | Liberación controlada de compuestos activos desde conjugados macromoleculares |
| JP2012000072A (ja) * | 2010-06-18 | 2012-01-05 | Japan Health Science Foundation | 新規な抗フィブリン抗体 |
| TW201215412A (en) * | 2010-08-30 | 2012-04-16 | Sun Pharma Advanced Res Co Ltd | Stable pharmaceutical composition |
| EP2654795B1 (en) * | 2010-12-21 | 2018-03-07 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of pemetrexed-based compounds |
| WO2013036857A1 (en) * | 2011-09-07 | 2013-03-14 | Prolynx Llc | Sulfone linkers |
| MX371201B (es) * | 2013-10-04 | 2020-01-22 | Prolynx Llc | Conjugados de liberación lenta de sn-38. |
-
2014
- 2014-10-03 MX MX2016004299A patent/MX371201B/es active IP Right Grant
- 2014-10-03 ES ES14796322T patent/ES2759905T3/es active Active
- 2014-10-03 AU AU2014331591A patent/AU2014331591B2/en active Active
- 2014-10-03 DK DK14796322.7T patent/DK3052101T3/da active
- 2014-10-03 US US15/026,579 patent/US10016411B2/en active Active
- 2014-10-03 TW TW103134678A patent/TWI716342B/zh active
- 2014-10-03 CA CA2925132A patent/CA2925132C/en active Active
- 2014-10-03 EP EP14796322.7A patent/EP3052101B1/en active Active
- 2014-10-03 KR KR1020167011936A patent/KR102320753B1/ko active Active
- 2014-10-03 CN CN201480062543.4A patent/CN106061483B/zh active Active
- 2014-10-03 JP JP2016520004A patent/JP6473145B2/ja active Active
- 2014-10-03 WO PCT/US2014/059146 patent/WO2015051307A1/en not_active Ceased
- 2014-10-03 SG SG11201602258WA patent/SG11201602258WA/en unknown
- 2014-10-03 SG SG10201811365RA patent/SG10201811365RA/en unknown
- 2014-10-03 BR BR112016007410-6A patent/BR112016007410B1/pt active IP Right Grant
-
2018
- 2018-06-14 US US16/009,078 patent/US10342792B2/en active Active
- 2018-11-01 AU AU2018256608A patent/AU2018256608A1/en not_active Abandoned
-
2019
- 2019-01-24 JP JP2019010029A patent/JP6842479B2/ja active Active
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