JP2014526558A5 - - Google Patents
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- Publication number
- JP2014526558A5 JP2014526558A5 JP2014531995A JP2014531995A JP2014526558A5 JP 2014526558 A5 JP2014526558 A5 JP 2014526558A5 JP 2014531995 A JP2014531995 A JP 2014531995A JP 2014531995 A JP2014531995 A JP 2014531995A JP 2014526558 A5 JP2014526558 A5 JP 2014526558A5
- Authority
- JP
- Japan
- Prior art keywords
- romidepsin
- azacitidine
- use according
- amount
- per day
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- OHRURASPPZQGQM-GCCNXGTGSA-N romidepsin Chemical compound O1C(=O)[C@H](C(C)C)NC(=O)C(=C/C)/NC(=O)[C@H]2CSSCC\C=C\[C@@H]1CC(=O)N[C@H](C(C)C)C(=O)N2 OHRURASPPZQGQM-GCCNXGTGSA-N 0.000 claims 13
- 229960003452 romidepsin Drugs 0.000 claims 13
- OHRURASPPZQGQM-UHFFFAOYSA-N romidepsin Natural products O1C(=O)C(C(C)C)NC(=O)C(=CC)NC(=O)C2CSSCCC=CC1CC(=O)NC(C(C)C)C(=O)N2 OHRURASPPZQGQM-UHFFFAOYSA-N 0.000 claims 13
- 108010091666 romidepsin Proteins 0.000 claims 13
- NMUSYJAQQFHJEW-KVTDHHQDSA-N 5-azacytidine Chemical compound O=C1N=C(N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 NMUSYJAQQFHJEW-KVTDHHQDSA-N 0.000 claims 12
- 229960002756 azacitidine Drugs 0.000 claims 12
- 201000005962 mycosis fungoides Diseases 0.000 claims 5
- 208000027190 Peripheral T-cell lymphomas Diseases 0.000 claims 4
- 208000031673 T-Cell Cutaneous Lymphoma Diseases 0.000 claims 4
- 208000031672 T-Cell Peripheral Lymphoma Diseases 0.000 claims 4
- 201000007241 cutaneous T cell lymphoma Diseases 0.000 claims 4
- 208000020968 mature T-cell and NK-cell non-Hodgkin lymphoma Diseases 0.000 claims 4
- 208000025638 primary cutaneous T-cell non-Hodgkin lymphoma Diseases 0.000 claims 4
- 206010042971 T-cell lymphoma Diseases 0.000 claims 3
- 208000027585 T-cell non-Hodgkin lymphoma Diseases 0.000 claims 3
- 238000001990 intravenous administration Methods 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 208000009359 Sezary Syndrome Diseases 0.000 claims 1
- 208000021388 Sezary disease Diseases 0.000 claims 1
- 238000011443 conventional therapy Methods 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161538734P | 2011-09-23 | 2011-09-23 | |
| US61/538,734 | 2011-09-23 | ||
| US201261698441P | 2012-09-07 | 2012-09-07 | |
| US61/698,441 | 2012-09-07 | ||
| PCT/US2012/056485 WO2013043967A1 (en) | 2011-09-23 | 2012-09-21 | Romidepsin and 5 - azacitidine for use in treating lymphoma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014526558A JP2014526558A (ja) | 2014-10-06 |
| JP2014526558A5 true JP2014526558A5 (enExample) | 2016-02-04 |
Family
ID=47045157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014531995A Pending JP2014526558A (ja) | 2011-09-23 | 2012-09-21 | リンパ腫の治療に使用するためのロミデプシン及び５−アザシチジン |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20130085115A1 (enExample) |
| EP (1) | EP2758067A1 (enExample) |
| JP (1) | JP2014526558A (enExample) |
| KR (1) | KR20140069225A (enExample) |
| CN (1) | CN104114182A (enExample) |
| AU (1) | AU2012312308B2 (enExample) |
| CA (1) | CA2849708A1 (enExample) |
| HK (1) | HK1200330A1 (enExample) |
| IL (1) | IL231636A0 (enExample) |
| MX (1) | MX2014003467A (enExample) |
| WO (1) | WO2013043967A1 (enExample) |
| ZA (1) | ZA201402151B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150359810A1 (en) * | 2014-06-17 | 2015-12-17 | Celgene Corporation | Methods for treating epstein-barr virus (ebv) associated cancers using oral formulations of 5-azacytidine |
| US20200276220A1 (en) * | 2016-07-07 | 2020-09-03 | MiRagen Therapeutics, Inc. | Methods for treating cutaneous t-cell lymphoma (ctcl) with mir-155 inhibitors |
| JP7258224B2 (ja) * | 2020-03-16 | 2023-04-14 | 株式会社マンダム | Ｔ細胞性リンパ腫の指標の検出方法、及びその利用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4328245A (en) | 1981-02-13 | 1982-05-04 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4410545A (en) | 1981-02-13 | 1983-10-18 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4409239A (en) | 1982-01-21 | 1983-10-11 | Syntex (U.S.A.) Inc. | Propylene glycol diester solutions of PGE-type compounds |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| GB8817743D0 (en) | 1988-07-26 | 1988-09-01 | Fujisawa Pharmaceutical Co | Fr901228 substance & preparation thereof |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| JPH064872A (ja) | 1992-06-19 | 1994-01-14 | Sony Corp | 光ディスク再生装置 |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US6350458B1 (en) | 1998-02-10 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Mixed micellar drug deliver system and method of preparation |
| JP2004508049A (ja) | 2000-09-01 | 2004-03-18 | 藤沢薬品工業株式会社 | Ｆｒ９０１２２８物質の製造法 |
| US6887855B2 (en) | 2003-03-17 | 2005-05-03 | Pharmion Corporation | Forms of 5-azacytidine |
| US7038038B2 (en) | 2003-03-17 | 2006-05-02 | Pharmion Corporation | Synthesis of 5-azacytidine |
| US6943249B2 (en) | 2003-03-17 | 2005-09-13 | Ash Stevens, Inc. | Methods for isolating crystalline Form I of 5-azacytidine |
| EP1482418A1 (en) | 2003-05-28 | 2004-12-01 | Sap Ag | A data processing method and system |
| ES2444890T3 (es) * | 2006-03-31 | 2014-02-27 | Erasmus University Medical Center Rotterdam | Nueva composición para el control del crecimiento tumoral |
| CA2649877A1 (en) * | 2006-04-24 | 2007-12-21 | Gloucester Pharmaceuticals | Gemcitabine combination therapy |
| EP2040731A4 (en) * | 2006-06-09 | 2010-05-19 | Merrion Res Iii Ltd | SOLID DOSAGE FORM FOR ORAL ADMINISTRATION CONTAINING AN ACTIVATOR |
| GB0625283D0 (en) * | 2006-12-19 | 2007-01-24 | Cyclacel Ltd | Combination |
| JP2012506428A (ja) * | 2008-10-24 | 2012-03-15 | グルオウセステル プハルマセウトイカルス | ガンの療法 |
-
2012
- 2012-09-21 CN CN201280057857.6A patent/CN104114182A/zh active Pending
- 2012-09-21 AU AU2012312308A patent/AU2012312308B2/en not_active Ceased
- 2012-09-21 HK HK15100777.2A patent/HK1200330A1/xx unknown
- 2012-09-21 CA CA2849708A patent/CA2849708A1/en not_active Abandoned
- 2012-09-21 KR KR1020147010755A patent/KR20140069225A/ko not_active Withdrawn
- 2012-09-21 US US13/624,807 patent/US20130085115A1/en not_active Abandoned
- 2012-09-21 EP EP12775088.3A patent/EP2758067A1/en not_active Withdrawn
- 2012-09-21 JP JP2014531995A patent/JP2014526558A/ja active Pending
- 2012-09-21 MX MX2014003467A patent/MX2014003467A/es not_active Application Discontinuation
- 2012-09-21 WO PCT/US2012/056485 patent/WO2013043967A1/en not_active Ceased
-
2014
- 2014-03-20 IL IL231636A patent/IL231636A0/en unknown
- 2014-03-24 ZA ZA2014/02151A patent/ZA201402151B/en unknown
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