JP2016539156A5 - - Google Patents

Download PDF

Info

Publication number
JP2016539156A5
JP2016539156A5 JP2016536593A JP2016536593A JP2016539156A5 JP 2016539156 A5 JP2016539156 A5 JP 2016539156A5 JP 2016536593 A JP2016536593 A JP 2016536593A JP 2016536593 A JP2016536593 A JP 2016536593A JP 2016539156 A5 JP2016539156 A5 JP 2016539156A5
Authority
JP
Japan
Prior art keywords
composition
effective amount
therapeutically effective
patient
lymphoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016536593A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016539156A (ja
JP6525474B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/069005 external-priority patent/WO2015085289A1/en
Publication of JP2016539156A publication Critical patent/JP2016539156A/ja
Publication of JP2016539156A5 publication Critical patent/JP2016539156A5/ja
Application granted granted Critical
Publication of JP6525474B2 publication Critical patent/JP6525474B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016536593A 2013-12-06 2014-12-08 オーロラキナーゼ阻害剤と抗cd30抗体の併用 Expired - Fee Related JP6525474B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361912785P 2013-12-06 2013-12-06
US61/912,785 2013-12-06
PCT/US2014/069005 WO2015085289A1 (en) 2013-12-06 2014-12-08 Combination of aurora kinase inhibitors and anti-cd30 antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019037397A Division JP2019081799A (ja) 2013-12-06 2019-03-01 オーロラキナーゼ阻害剤と抗cd30抗体の併用

Publications (3)

Publication Number Publication Date
JP2016539156A JP2016539156A (ja) 2016-12-15
JP2016539156A5 true JP2016539156A5 (enExample) 2018-01-11
JP6525474B2 JP6525474B2 (ja) 2019-06-05

Family

ID=53274204

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2016536593A Expired - Fee Related JP6525474B2 (ja) 2013-12-06 2014-12-08 オーロラキナーゼ阻害剤と抗cd30抗体の併用
JP2019037397A Pending JP2019081799A (ja) 2013-12-06 2019-03-01 オーロラキナーゼ阻害剤と抗cd30抗体の併用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019037397A Pending JP2019081799A (ja) 2013-12-06 2019-03-01 オーロラキナーゼ阻害剤と抗cd30抗体の併用

Country Status (4)

Country Link
US (1) US10335494B2 (enExample)
EP (1) EP3076963A4 (enExample)
JP (2) JP6525474B2 (enExample)
WO (1) WO2015085289A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI573792B (zh) 2012-02-01 2017-03-11 歐陸斯迪公司 新穎治療劑
GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409488D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
MA45862A (fr) * 2016-08-04 2021-05-05 Millennium Pharm Inc Combinaison d'inhibiteurs du protéasome et d'anticorps anti-cd30
WO2018068832A1 (en) 2016-10-11 2018-04-19 Euro-Celtique S.A. Hodgkin lymphoma therapy
US11357776B2 (en) * 2016-10-28 2022-06-14 Acetylon Pharmaceuticals, Inc. Pharmaceutical combinations comprising a histone deacetylase inhibitor and an aurora kinase inhibitor and methods of use thereof
MA46759A (fr) * 2016-11-14 2019-09-18 Millennium Pharm Inc Dosage de conjugués anticorps-médicament anti-cd30 pour humain non adulte
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
EP3897626B1 (en) 2018-12-18 2025-09-10 Mundipharma International Corporation Limited Tinostamustine for treating multiple myeloma
EP3961944A4 (en) 2019-04-23 2022-06-08 Panasonic Intellectual Property Corporation of America BASE STATION, TERMINAL AND COMMUNICATION METHOD
CA3151403A1 (en) * 2020-02-27 2021-09-02 National University Corporation Hokkaido University Method for screening anticancer agent and combination drug of kinase inhibitors for treatment of pancreatic cancer

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474893A (en) 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4714681A (en) 1981-07-01 1987-12-22 The Board Of Reagents, The University Of Texas System Cancer Center Quadroma cells and trioma cells and methods for the production of same
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4925648A (en) 1988-07-29 1990-05-15 Immunomedics, Inc. Detection and treatment of infectious and inflammatory lesions
US5601819A (en) 1988-08-11 1997-02-11 The General Hospital Corporation Bispecific antibodies for selective immune regulation and for selective immune cell binding
EP0739904A1 (en) 1989-06-29 1996-10-30 Medarex, Inc. Bispecific reagents for aids therapy
EP1690935A3 (en) 1990-01-12 2008-07-30 Abgenix, Inc. Generation of xenogeneic antibodies
DK0553244T4 (da) 1990-10-05 2005-08-01 Celldex Therapeutics Inc Målrettet immunostimulering med bispecifikke reagenser
AU8727291A (en) 1990-10-29 1992-06-11 Cetus Oncology Corporation Bispecific antibodies, method of production, and uses thereof
EP0582595A1 (en) 1991-04-26 1994-02-16 Surface Active Limited Novel antibodies, and methods for their use
EP1306095A3 (en) 1992-03-05 2003-06-25 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
US6111166A (en) 1994-09-19 2000-08-29 Medarex, Incorporated Transgenic mice expressing human Fcα and β receptors
MY141867A (en) 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
ES2369542T3 (es) * 2002-07-31 2011-12-01 Seattle Genetics, Inc. Conjugados de auristatina y su uso para tratar cáncer, una enfermedad autoinmune o una enfermedad infecciosa.
GB0226583D0 (en) 2002-11-14 2002-12-18 Cyclacel Ltd Compounds
UA83814C2 (ru) 2002-12-24 2008-08-26 Астразенека Аб Производные фосфонооксихиназолина и их фармацевтическое применение
BRPI0407544A (pt) 2003-02-17 2006-02-14 Pharmacia Italia Spa derivados de pirazol tetracìclicos como inibidores da cinase, processo para a sua preparação e composições farmacêuticas que os compreendem
TWI372050B (en) 2003-07-03 2012-09-11 Astex Therapeutics Ltd (morpholin-4-ylmethyl-1h-benzimidazol-2-yl)-1h-pyrazoles
GB0315657D0 (en) 2003-07-03 2003-08-13 Astex Technology Ltd Pharmaceutical compounds
US7141568B2 (en) 2003-07-09 2006-11-28 Pfizer Italia S.R.L. Pyrrolo[3,4-c]pyrazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
DK1663242T3 (da) 2003-08-07 2011-08-01 Rigel Pharmaceuticals Inc 2,4-Pyrimidindiamin-forbindelser og anvendelse som antiproliferative midler
KR101792651B1 (ko) 2004-05-14 2017-11-20 밀레니엄 파머슈티컬스 인코퍼레이티드 아우로라 키나아제의 억제에 의해 유사분열 진행을 억제하기 위한 화합물 및 그 화합물을 포함하는 약학적 조성물
JP4812763B2 (ja) 2004-05-18 2011-11-09 ライジェル ファーマシューティカルズ, インコーポレイテッド シクロアルキル置換ピリミジンジアミン化合物およびそれらの用途
JP2008505167A (ja) 2004-07-05 2008-02-21 アステックス、セラピューティックス、リミテッド 医薬組成物
DE602005024274D1 (de) 2004-07-16 2010-12-02 Sunesis Pharmaceuticals Inc Als aurora-kinase-inhibitoren nutzbare thienopyrimidine
MX2007003533A (es) * 2004-10-01 2007-05-23 Medarex Inc Metodos de tratar linfomas cd30 positivas.
DE602005012597D1 (de) 2004-11-15 2009-03-19 Rigel Pharmaceuticals Inc Verfahren zur herstellung optisch aktiver n-carbamat-geschützter beta-lactame durch optische auflösung unter verwendung einer candida antarctica lipase
GB2420559B (en) 2004-11-15 2008-08-06 Rigel Pharmaceuticals Inc Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
WO2006070192A1 (en) 2004-12-30 2006-07-06 Astex Therapeutics Limited Thiazole and isothiazole derivatives that modulate the acivity of cdk, gsk and aurora kynases
WO2006070202A1 (en) 2004-12-30 2006-07-06 Astex Therapeutics Limited Pyrazole derivatives having kinase modulating activity
EP1836188A1 (en) 2004-12-30 2007-09-26 Astex Therapeutics Limited Pyrazole derivatives as that modulate the activity of cdk, gsk and aurora kinases
MX2007008008A (es) 2004-12-30 2007-11-12 Astex Therapeutics Ltd Compuestos de pirazol que modulan la actividad de las cinasas cdk, gsk y aurora.
US7485661B2 (en) 2005-01-18 2009-02-03 Pfizer Italia S.R.L. Heterobicyclic pyrazole derivatives as kinase inhibitors
BRPI0616630B8 (pt) 2005-09-30 2021-05-25 Miikana Therapeutics Inc compostos de pirazol substituídos
JP5249770B2 (ja) 2005-11-03 2013-07-31 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼインヒビターとして有用なアミノピリジン
TW200808311A (en) 2006-03-30 2008-02-16 Nerviano Medical Sciences Srl Use of a kinase inhibitor for the treatment of particular resistant tumors
GB0609530D0 (en) 2006-05-12 2006-06-21 Cyclacel Ltd Combination
WO2007132221A1 (en) 2006-05-12 2007-11-22 Cyclacel Limited Combined anticancer pyrimidine-thiazole aurora kinase inhibitors
WO2007132220A1 (en) 2006-05-12 2007-11-22 Cyclacel Limited Combination of a 2-substituted-4-heter0aryl-pyrimidine amine with a cytotoxic drug and use thereof in the treatment of a proliferative disorder
WO2008021038A2 (en) 2006-08-09 2008-02-21 Millennium Pharmaceuticals, Inc. Pyridobenzazepine compounds and methods for inhibiting mitotic progression
CL2007003244A1 (es) 2006-11-16 2008-04-04 Millennium Pharm Inc Compuestos derivados de pirimido[5,4-d][2]benzazepina; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cancer.
CN102264368B (zh) 2008-12-22 2014-09-10 米伦纽姆医药公司 极光激酶抑制剂与抗cd20抗体的组合
WO2010081004A1 (en) 2009-01-09 2010-07-15 Seattle Genetics, Inc. Weekly dosing regimens for anti-cd30 vc-pab-mmae antibody drug-conjugates
JO3635B1 (ar) 2009-05-18 2020-08-27 Millennium Pharm Inc مركبات صيدلانية صلبة وطرق لانتاجها
JO3434B1 (ar) 2009-07-31 2019-10-20 Millennium Pharm Inc مركبات صيدلانية لمعالجة السرطان وامراض واضطرابات اخري
WO2011103089A1 (en) 2010-02-19 2011-08-25 Millennium Pharmaceuticals, Inc. Crystalline forms of sodium 4-{[9-chloro-7-(2-fluoro-6--methoxyphenyl)-5h -pyrimido[5,4-d][2]benzazepin-2yl]amino}-2-methoxybenzoate
US20130004481A1 (en) * 2011-01-12 2013-01-03 Boehringer Ingelheim International Gmbh Anticancer therapy

Similar Documents

Publication Publication Date Title
JP2010536849A5 (enExample)
EA201270221A1 (ru) Лечение болезни крона с применением лаквинимода
JP2019515908A5 (enExample)
JP2009525343A5 (enExample)
JP2012515184A5 (enExample)
PH12021552282A1 (en) Crystalline forms of a bruton`s tyrosine kinase inhibitor
JP2012193216A5 (enExample)
JP2012524089A5 (enExample)
JP2011522896A5 (enExample)
JP2012532874A5 (enExample)
JP2013542247A5 (enExample)
JP2013507415A5 (enExample)
MX2010010026A (es) Agente para tratar enfermedad.
RU2015102772A (ru) Бензодиазелипы для мелкоклеточного рака легкого
JP2016147915A5 (enExample)
JP2012512158A5 (enExample)
PH12014502447A1 (en) Use of high dose laquinimod for treating multiple sclerosis
HRP20120918T1 (hr) Aminopirazolski spoj
JP2009280621A5 (enExample)
JP2015522630A5 (enExample)
JP2018090566A5 (enExample)
JP2016516816A5 (enExample)
JP2019535760A5 (ja) ガボキサドールを用いた注意欠陥多動性障害(adhd)の治療方法
JP2015527374A5 (enExample)
JP2015507020A5 (enExample)