ZA201402151B - Romidepsin and 5- azacitidine for use in treating lymphoma - Google Patents
Romidepsin and 5- azacitidine for use in treating lymphomaInfo
- Publication number
- ZA201402151B ZA201402151B ZA2014/02151A ZA201402151A ZA201402151B ZA 201402151 B ZA201402151 B ZA 201402151B ZA 2014/02151 A ZA2014/02151 A ZA 2014/02151A ZA 201402151 A ZA201402151 A ZA 201402151A ZA 201402151 B ZA201402151 B ZA 201402151B
- Authority
- ZA
- South Africa
- Prior art keywords
- romidepsin
- azacitidine
- treating lymphoma
- lymphoma
- treating
- Prior art date
Links
- NMUSYJAQQFHJEW-KVTDHHQDSA-N 5-azacytidine Chemical compound O=C1N=C(N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 NMUSYJAQQFHJEW-KVTDHHQDSA-N 0.000 title 1
- 206010025323 Lymphomas Diseases 0.000 title 1
- OHRURASPPZQGQM-GCCNXGTGSA-N romidepsin Chemical compound O1C(=O)[C@H](C(C)C)NC(=O)C(=C/C)/NC(=O)[C@H]2CSSCC\C=C\[C@@H]1CC(=O)N[C@H](C(C)C)C(=O)N2 OHRURASPPZQGQM-GCCNXGTGSA-N 0.000 title 1
- 229960003452 romidepsin Drugs 0.000 title 1
- OHRURASPPZQGQM-UHFFFAOYSA-N romidepsin Natural products O1C(=O)C(C(C)C)NC(=O)C(=CC)NC(=O)C2CSSCCC=CC1CC(=O)NC(C(C)C)C(=O)N2 OHRURASPPZQGQM-UHFFFAOYSA-N 0.000 title 1
- 108010091666 romidepsin Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161538734P | 2011-09-23 | 2011-09-23 | |
| US201261698441P | 2012-09-07 | 2012-09-07 | |
| PCT/US2012/056485 WO2013043967A1 (en) | 2011-09-23 | 2012-09-21 | Romidepsin and 5 - azacitidine for use in treating lymphoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201402151B true ZA201402151B (en) | 2015-06-24 |
Family
ID=47045157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2014/02151A ZA201402151B (en) | 2011-09-23 | 2014-03-24 | Romidepsin and 5- azacitidine for use in treating lymphoma |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20130085115A1 (enExample) |
| EP (1) | EP2758067A1 (enExample) |
| JP (1) | JP2014526558A (enExample) |
| KR (1) | KR20140069225A (enExample) |
| CN (1) | CN104114182A (enExample) |
| AU (1) | AU2012312308B2 (enExample) |
| CA (1) | CA2849708A1 (enExample) |
| HK (1) | HK1200330A1 (enExample) |
| IL (1) | IL231636A0 (enExample) |
| MX (1) | MX2014003467A (enExample) |
| WO (1) | WO2013043967A1 (enExample) |
| ZA (1) | ZA201402151B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015195634A1 (en) * | 2014-06-17 | 2015-12-23 | Celgne Corporation | Methods for treating epstein-barr virus (ebv) associated cancers using oral formulations of 5-azacytidine |
| WO2018009855A1 (en) * | 2016-07-07 | 2018-01-11 | MiRagen Therapeutics, Inc. | Methods for treating cutaneous t-cell lymphoma (ctcl) with mir-155 inhibitors |
| WO2021186855A1 (ja) * | 2020-03-16 | 2021-09-23 | 株式会社マンダム | Ｔ細胞性リンパ腫の指標の検出方法、及びその利用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4410545A (en) | 1981-02-13 | 1983-10-18 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4328245A (en) | 1981-02-13 | 1982-05-04 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4409239A (en) | 1982-01-21 | 1983-10-11 | Syntex (U.S.A.) Inc. | Propylene glycol diester solutions of PGE-type compounds |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| GB8817743D0 (en) | 1988-07-26 | 1988-09-01 | Fujisawa Pharmaceutical Co | Fr901228 substance & preparation thereof |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| JPH064872A (ja) | 1992-06-19 | 1994-01-14 | Sony Corp | 光ディスク再生装置 |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US6350458B1 (en) | 1998-02-10 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Mixed micellar drug deliver system and method of preparation |
| AU2001280109A1 (en) | 2000-09-01 | 2002-03-22 | Fujisawa Pharmaceutical Co. Ltd. | A method of producing fr901228 |
| US6887855B2 (en) | 2003-03-17 | 2005-05-03 | Pharmion Corporation | Forms of 5-azacytidine |
| US6943249B2 (en) | 2003-03-17 | 2005-09-13 | Ash Stevens, Inc. | Methods for isolating crystalline Form I of 5-azacytidine |
| US7038038B2 (en) | 2003-03-17 | 2006-05-02 | Pharmion Corporation | Synthesis of 5-azacytidine |
| EP1482418A1 (en) | 2003-05-28 | 2004-12-01 | Sap Ag | A data processing method and system |
| ES2444890T3 (es) * | 2006-03-31 | 2014-02-27 | Erasmus University Medical Center Rotterdam | Nueva composición para el control del crecimiento tumoral |
| US20100137239A1 (en) * | 2006-04-24 | 2010-06-03 | Gloucester Pharmaceuticals | Gemcitabine combination therapy |
| CA2654566A1 (en) * | 2006-06-09 | 2007-12-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
| GB0625283D0 (en) * | 2006-12-19 | 2007-01-24 | Cyclacel Ltd | Combination |
| US20110269699A1 (en) * | 2008-10-24 | 2011-11-03 | Mitchell Keegan | Cancer therapy |
-
2012
- 2012-09-21 EP EP12775088.3A patent/EP2758067A1/en not_active Withdrawn
- 2012-09-21 CA CA2849708A patent/CA2849708A1/en not_active Abandoned
- 2012-09-21 HK HK15100777.2A patent/HK1200330A1/xx unknown
- 2012-09-21 WO PCT/US2012/056485 patent/WO2013043967A1/en not_active Ceased
- 2012-09-21 JP JP2014531995A patent/JP2014526558A/ja active Pending
- 2012-09-21 CN CN201280057857.6A patent/CN104114182A/zh active Pending
- 2012-09-21 MX MX2014003467A patent/MX2014003467A/es not_active Application Discontinuation
- 2012-09-21 AU AU2012312308A patent/AU2012312308B2/en not_active Ceased
- 2012-09-21 US US13/624,807 patent/US20130085115A1/en not_active Abandoned
- 2012-09-21 KR KR1020147010755A patent/KR20140069225A/ko not_active Withdrawn
-
2014
- 2014-03-20 IL IL231636A patent/IL231636A0/en unknown
- 2014-03-24 ZA ZA2014/02151A patent/ZA201402151B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2014003467A (es) | 2014-07-30 |
| HK1200330A1 (en) | 2015-08-07 |
| CN104114182A (zh) | 2014-10-22 |
| EP2758067A1 (en) | 2014-07-30 |
| CA2849708A1 (en) | 2013-03-28 |
| WO2013043967A1 (en) | 2013-03-28 |
| US20130085115A1 (en) | 2013-04-04 |
| IL231636A0 (en) | 2014-05-28 |
| AU2012312308A1 (en) | 2013-05-02 |
| AU2012312308B2 (en) | 2015-11-19 |
| KR20140069225A (ko) | 2014-06-09 |
| JP2014526558A (ja) | 2014-10-06 |
| NZ622752A (en) | 2016-06-24 |
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