JP2011157399A5 - - Google Patents
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- Publication number
- JP2011157399A5 JP2011157399A5 JP2011112835A JP2011112835A JP2011157399A5 JP 2011157399 A5 JP2011157399 A5 JP 2011157399A5 JP 2011112835 A JP2011112835 A JP 2011112835A JP 2011112835 A JP2011112835 A JP 2011112835A JP 2011157399 A5 JP2011157399 A5 JP 2011157399A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharmaceutical composition
- virus
- myxoma virus
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 38
- 241000700562 Myxoma virus Species 0.000 claims 23
- 206010028980 Neoplasm Diseases 0.000 claims 23
- 201000011510 cancer Diseases 0.000 claims 19
- 241000700605 Viruses Species 0.000 claims 15
- 208000036142 Viral infection Diseases 0.000 claims 12
- 230000009385 viral infection Effects 0.000 claims 12
- 201000010099 disease Diseases 0.000 claims 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 9
- 208000037581 Persistent Infection Diseases 0.000 claims 8
- 210000004027 cell Anatomy 0.000 claims 8
- 210000005260 human cell Anatomy 0.000 claims 8
- 230000001575 pathological effect Effects 0.000 claims 8
- 230000002035 prolonged effect Effects 0.000 claims 8
- 230000002085 persistent effect Effects 0.000 claims 7
- 206010009944 Colon cancer Diseases 0.000 claims 6
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 6
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 6
- 206010033128 Ovarian cancer Diseases 0.000 claims 6
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 6
- 206010060862 Prostate cancer Diseases 0.000 claims 6
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 6
- 206010038389 Renal cancer Diseases 0.000 claims 6
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 6
- 201000010982 kidney cancer Diseases 0.000 claims 6
- 201000005202 lung cancer Diseases 0.000 claims 6
- 208000020816 lung neoplasm Diseases 0.000 claims 6
- 201000001441 melanoma Diseases 0.000 claims 6
- 102000014150 Interferons Human genes 0.000 claims 5
- 108010050904 Interferons Proteins 0.000 claims 5
- 229940079322 interferon Drugs 0.000 claims 5
- 230000001684 chronic effect Effects 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 4
- 206010003571 Astrocytoma Diseases 0.000 claims 3
- 206010004593 Bile duct cancer Diseases 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 3
- 208000026310 Breast neoplasm Diseases 0.000 claims 3
- 201000009030 Carcinoma Diseases 0.000 claims 3
- 206010008342 Cervix carcinoma Diseases 0.000 claims 3
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 3
- 206010014733 Endometrial cancer Diseases 0.000 claims 3
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 3
- 208000032612 Glial tumor Diseases 0.000 claims 3
- 206010018338 Glioma Diseases 0.000 claims 3
- 206010025323 Lymphomas Diseases 0.000 claims 3
- 208000003445 Mouth Neoplasms Diseases 0.000 claims 3
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 3
- 208000009565 Pharyngeal Neoplasms Diseases 0.000 claims 3
- 206010034811 Pharyngeal cancer Diseases 0.000 claims 3
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 3
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 3
- 208000026900 bile duct neoplasm Diseases 0.000 claims 3
- 201000010881 cervical cancer Diseases 0.000 claims 3
- 208000006990 cholangiocarcinoma Diseases 0.000 claims 3
- 208000029742 colonic neoplasm Diseases 0.000 claims 3
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 3
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 3
- 230000002401 inhibitory effect Effects 0.000 claims 3
- 208000032839 leukemia Diseases 0.000 claims 3
- 208000012987 lip and oral cavity carcinoma Diseases 0.000 claims 3
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 3
- 201000002528 pancreatic cancer Diseases 0.000 claims 3
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 3
- 206010041823 squamous cell carcinoma Diseases 0.000 claims 3
- 201000002510 thyroid cancer Diseases 0.000 claims 3
- 230000002159 abnormal effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 230000011664 signaling Effects 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 210000004748 cultured cell Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000002459 sustained effect Effects 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45252103P | 2003-03-07 | 2003-03-07 | |
| US60/452,521 | 2003-03-07 | ||
| US45539303P | 2003-03-18 | 2003-03-18 | |
| US60/455,393 | 2003-03-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006504071A Division JP4800924B2 (ja) | 2003-03-07 | 2004-03-08 | 癌および慢性ウイルス感染の治療処置のための粘液腫症ウイルスの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011157399A JP2011157399A (ja) | 2011-08-18 |
| JP2011157399A5 true JP2011157399A5 (enExample) | 2011-10-06 |
Family
ID=32965588
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006504071A Expired - Fee Related JP4800924B2 (ja) | 2003-03-07 | 2004-03-08 | 癌および慢性ウイルス感染の治療処置のための粘液腫症ウイルスの使用 |
| JP2011112835A Withdrawn JP2011157399A (ja) | 2003-03-07 | 2011-05-19 | 癌および慢性ウイルス感染の治療処置のための粘液腫症ウイルスの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006504071A Expired - Fee Related JP4800924B2 (ja) | 2003-03-07 | 2004-03-08 | 癌および慢性ウイルス感染の治療処置のための粘液腫症ウイルスの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7582614B2 (enExample) |
| EP (1) | EP1601376B1 (enExample) |
| JP (2) | JP4800924B2 (enExample) |
| KR (1) | KR101116858B1 (enExample) |
| AU (1) | AU2004216928B2 (enExample) |
| CA (1) | CA2517147C (enExample) |
| IL (1) | IL170601A (enExample) |
| MX (1) | MXPA05009526A (enExample) |
| NZ (1) | NZ541951A (enExample) |
| RU (1) | RU2362584C2 (enExample) |
| WO (1) | WO2004078206A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7582614B2 (en) * | 2003-03-07 | 2009-09-01 | Robarts Research Institute | Use of myxoma virus for the therapeutic treatment of cancer and chronic viral infection |
| DE102004003572A1 (de) * | 2004-01-23 | 2005-08-18 | Bavarian Nordic A/S | Monoparamunitätsinducer basierend auf attenuierten Myxomaviren des Kaninchens |
| CN101137748B (zh) * | 2005-03-07 | 2011-12-14 | 罗巴斯研究机构 | 粘液瘤病毒与雷帕霉素的组合在治疗性处理中的应用 |
| CA2951453A1 (en) | 2006-06-01 | 2007-12-13 | The University Of Western Ontario | Myxoma virus mutants for cancer treatment |
| WO2007143538A2 (en) * | 2006-06-01 | 2007-12-13 | Robarts Research Institute | Pike-a enhances infection by myxoma virus |
| ES2663844T3 (es) * | 2011-06-09 | 2018-04-17 | University Of Florida Research Foundation, Inc. | Métodos de prevención o tratamiento de enfermedad injerto contra huésped |
| ES2827012T3 (es) * | 2016-11-17 | 2021-05-19 | Vcn Biosciences Sl | Uso de vectores virales oncolíticos en el tratamiento del retinoblastoma |
| US20200308550A1 (en) | 2017-09-11 | 2020-10-01 | Imba - Institut Für Molekulare Biotechnologie Gmbh | Tumor organoid model |
| KR20190109379A (ko) * | 2018-03-16 | 2019-09-25 | 바이로큐어 주식회사 | 암 치료를 위한 레오바이러스 및 믹소마폭스 바이러스의 병용 |
| RU2699754C1 (ru) * | 2018-05-08 | 2019-09-09 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский национальный исследовательский государственный университет имени Н.Г. Чернышевского" | Флуоресцирующая клеточная линия глиомы и способ её получения |
| WO2019227022A1 (en) | 2018-05-25 | 2019-11-28 | Bioventures, Llc | Myxoma virus compositions and methods of use |
| US20220403001A1 (en) | 2018-06-12 | 2022-12-22 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
| US20210169957A1 (en) * | 2018-08-17 | 2021-06-10 | Virocure, Inc. | Combined use of squirrel poxvirus and myxoma poxvirus, for treating cancer |
| EP3846829A4 (en) * | 2018-09-05 | 2022-09-14 | Arizona Board of Regents on behalf of Arizona State University | ONCOLYTIC VIRUS PLATFORM FOR THE TREATMENT OF HEMATOLOGICAL CANCER |
| US12428626B2 (en) | 2018-11-20 | 2025-09-30 | Bioventures, Llc | Cells for the production of viruses and methods of using the same |
| US11591616B1 (en) | 2019-04-22 | 2023-02-28 | Colorado State University Research Foundation | Apoptotic upregulation by myxoma virus expressing walleye dermal sarcoma virus orfC |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806347A (en) | 1985-12-11 | 1989-02-21 | Schering Corporation | Interferon combinations |
| GB9415320D0 (en) | 1994-07-29 | 1994-09-21 | Medical Res Council | Cancer treatment |
| AU1550797A (en) | 1996-01-25 | 1997-08-20 | Medical Research Council | Treatment of non-neuronal cancer using hsv mutant |
| CA2296319A1 (en) | 1997-07-18 | 1999-01-28 | Chiron Corporation | Lentiviral vectors |
| JP2001519175A (ja) | 1997-10-09 | 2001-10-23 | プロ − バイラス，インコーポレイテッド | ウイルスを用いた新生物の処置 |
| ES2153284B1 (es) | 1998-06-10 | 2001-09-01 | Fundacion Para El Estudio Y De | Nuevo virus recombinante de mixoma atenuado y su uso en la preparacion de vacunas mixtas contra la mixomatosis y la enfermedad hemorragica de los conejos. |
| MXPA01010393A (es) | 1999-04-15 | 2004-04-02 | Pro Virus Inc | Tratamiento de neoplasmas con virus. |
| WO2001004318A2 (en) | 1999-07-12 | 2001-01-18 | Viron Therapeutics, Inc. | Myxoma virus genes for immune modulation |
| US7582614B2 (en) * | 2003-03-07 | 2009-09-01 | Robarts Research Institute | Use of myxoma virus for the therapeutic treatment of cancer and chronic viral infection |
| WO2007143545A2 (en) | 2006-06-01 | 2007-12-13 | Robarts Research Institute | Tnf signaling in myxoma virus treatments |
-
2004
- 2004-03-08 US US10/547,859 patent/US7582614B2/en not_active Expired - Fee Related
- 2004-03-08 JP JP2006504071A patent/JP4800924B2/ja not_active Expired - Fee Related
- 2004-03-08 EP EP04718235A patent/EP1601376B1/en not_active Expired - Lifetime
- 2004-03-08 AU AU2004216928A patent/AU2004216928B2/en not_active Ceased
- 2004-03-08 CA CA2517147A patent/CA2517147C/en not_active Expired - Fee Related
- 2004-03-08 RU RU2005131020/15A patent/RU2362584C2/ru not_active IP Right Cessation
- 2004-03-08 MX MXPA05009526A patent/MXPA05009526A/es active IP Right Grant
- 2004-03-08 WO PCT/CA2004/000341 patent/WO2004078206A1/en not_active Ceased
- 2004-03-08 NZ NZ541951A patent/NZ541951A/en not_active IP Right Cessation
-
2005
- 2005-08-31 IL IL170601A patent/IL170601A/en unknown
- 2005-09-07 KR KR1020057016740A patent/KR101116858B1/ko not_active Expired - Fee Related
-
2009
- 2009-08-28 US US12/549,939 patent/US8227440B2/en not_active Expired - Fee Related
-
2011
- 2011-05-19 JP JP2011112835A patent/JP2011157399A/ja not_active Withdrawn
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