CA2517147C - Use of myxoma virus for the therapeutic treatment of cancer and chronic viral infection - Google Patents
Use of myxoma virus for the therapeutic treatment of cancer and chronic viral infection Download PDFInfo
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- CA2517147C CA2517147C CA2517147A CA2517147A CA2517147C CA 2517147 C CA2517147 C CA 2517147C CA 2517147 A CA2517147 A CA 2517147A CA 2517147 A CA2517147 A CA 2517147A CA 2517147 C CA2517147 C CA 2517147C
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45252103P | 2003-03-07 | 2003-03-07 | |
| US60/452,521 | 2003-03-07 | ||
| US45539303P | 2003-03-18 | 2003-03-18 | |
| US60/455,393 | 2003-03-18 | ||
| PCT/CA2004/000341 WO2004078206A1 (en) | 2003-03-07 | 2004-03-08 | Use of myxoma virus for the therapeutic treatment of cancer and chronic viral infection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2517147A1 CA2517147A1 (en) | 2004-09-16 |
| CA2517147C true CA2517147C (en) | 2011-06-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2517147A Expired - Fee Related CA2517147C (en) | 2003-03-07 | 2004-03-08 | Use of myxoma virus for the therapeutic treatment of cancer and chronic viral infection |
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| Country | Link |
|---|---|
| US (2) | US7582614B2 (enExample) |
| EP (1) | EP1601376B1 (enExample) |
| JP (2) | JP4800924B2 (enExample) |
| KR (1) | KR101116858B1 (enExample) |
| AU (1) | AU2004216928C1 (enExample) |
| CA (1) | CA2517147C (enExample) |
| IL (1) | IL170601A (enExample) |
| MX (1) | MXPA05009526A (enExample) |
| NZ (1) | NZ541951A (enExample) |
| RU (1) | RU2362584C2 (enExample) |
| WO (1) | WO2004078206A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1601376B1 (en) * | 2003-03-07 | 2012-05-30 | Robarts Research Institute | Use of myxoma virus for therapeutic treatment of cancer and chronic viral infection |
| DE102004003572A1 (de) * | 2004-01-23 | 2005-08-18 | Bavarian Nordic A/S | Monoparamunitätsinducer basierend auf attenuierten Myxomaviren des Kaninchens |
| NZ560840A (en) * | 2005-03-07 | 2009-07-31 | Robarts Res Inst | Use of a combination of myxoma virus and rapamycin for therapeutic treatment |
| WO2007143538A2 (en) * | 2006-06-01 | 2007-12-13 | Robarts Research Institute | Pike-a enhances infection by myxoma virus |
| KR20090014364A (ko) * | 2006-06-01 | 2009-02-10 | 로바츠 리서치 인스티튜트 | 암 치료용 점액종 바이러스 변이종 |
| DK2717887T3 (en) | 2011-06-09 | 2018-04-09 | Univ Florida | Methods for treating or preventing graft-versus-host disease |
| CN109982709A (zh) * | 2016-11-17 | 2019-07-05 | Vcn生物科学有限公司 | 病毒载体在治疗视网膜母细胞瘤中的用途 |
| CA3074901A1 (en) | 2017-09-11 | 2019-03-14 | Imba - Institut Fur Molekulare Biotechnologie Gmbh | Tumor organoid model |
| WO2019177438A1 (ko) * | 2018-03-16 | 2019-09-19 | 바이로큐어 주식회사 | 암 치료를 위한 레오바이러스 및 믹소마폭스 바이러스의 병용 |
| RU2699754C1 (ru) * | 2018-05-08 | 2019-09-09 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский национальный исследовательский государственный университет имени Н.Г. Чернышевского" | Флуоресцирующая клеточная линия глиомы и способ её получения |
| US12128099B2 (en) | 2018-05-25 | 2024-10-29 | Bioventures, Llc | Myxoma virus compositions and methods of use |
| WO2019241315A1 (en) | 2018-06-12 | 2019-12-19 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
| WO2020036341A1 (ko) * | 2018-08-17 | 2020-02-20 | 바이로큐어 주식회사 | 암 치료를 위한 다람쥐폭스 바이러스 및 믹소마폭스 바이러스의 병용 |
| WO2020051248A1 (en) * | 2018-09-05 | 2020-03-12 | Arizona Board Of Regents On Behalf Of Arizona State University | Oncolytic virus platform to treat hematological cancer |
| WO2020106880A1 (en) | 2018-11-20 | 2020-05-28 | Bioventures, Llc | Cells for the production of viruses and methods of using the same |
| US11591616B1 (en) | 2019-04-22 | 2023-02-28 | Colorado State University Research Foundation | Apoptotic upregulation by myxoma virus expressing walleye dermal sarcoma virus orfC |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806347A (en) | 1985-12-11 | 1989-02-21 | Schering Corporation | Interferon combinations |
| GB9415320D0 (en) | 1994-07-29 | 1994-09-21 | Medical Res Council | Cancer treatment |
| WO1997026904A1 (en) | 1996-01-25 | 1997-07-31 | Medical Research Council | Treatment of non-neuronal cancer using hsv mutant |
| WO1999004026A2 (en) | 1997-07-18 | 1999-01-28 | Chiron Corporation | Lentiviral vectors |
| IL135507A0 (en) | 1997-10-09 | 2001-05-20 | Pro Virus Inc | Treatment of neoplasms with viruses |
| ES2153284B1 (es) | 1998-06-10 | 2001-09-01 | Fundacion Para El Estudio Y De | Nuevo virus recombinante de mixoma atenuado y su uso en la preparacion de vacunas mixtas contra la mixomatosis y la enfermedad hemorragica de los conejos. |
| CN1477964A (zh) | 1999-04-15 | 2004-02-25 | 应用病毒治疗肿瘤 | |
| CA2378567A1 (en) * | 1999-07-12 | 2001-01-18 | Viron Therapeutics, Inc. | Novel myxoma genes for immune modulation |
| EP1601376B1 (en) * | 2003-03-07 | 2012-05-30 | Robarts Research Institute | Use of myxoma virus for therapeutic treatment of cancer and chronic viral infection |
| WO2007143545A2 (en) | 2006-06-01 | 2007-12-13 | Robarts Research Institute | Tnf signaling in myxoma virus treatments |
-
2004
- 2004-03-08 EP EP04718235A patent/EP1601376B1/en not_active Expired - Lifetime
- 2004-03-08 AU AU2004216928A patent/AU2004216928C1/en not_active Ceased
- 2004-03-08 WO PCT/CA2004/000341 patent/WO2004078206A1/en not_active Ceased
- 2004-03-08 JP JP2006504071A patent/JP4800924B2/ja not_active Expired - Fee Related
- 2004-03-08 MX MXPA05009526A patent/MXPA05009526A/es active IP Right Grant
- 2004-03-08 CA CA2517147A patent/CA2517147C/en not_active Expired - Fee Related
- 2004-03-08 US US10/547,859 patent/US7582614B2/en not_active Expired - Fee Related
- 2004-03-08 RU RU2005131020/15A patent/RU2362584C2/ru not_active IP Right Cessation
- 2004-03-08 NZ NZ541951A patent/NZ541951A/en not_active IP Right Cessation
-
2005
- 2005-08-31 IL IL170601A patent/IL170601A/en unknown
- 2005-09-07 KR KR1020057016740A patent/KR101116858B1/ko not_active Expired - Fee Related
-
2009
- 2009-08-28 US US12/549,939 patent/US8227440B2/en not_active Expired - Fee Related
-
2011
- 2011-05-19 JP JP2011112835A patent/JP2011157399A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1601376B1 (en) | 2012-05-30 |
| RU2005131020A (ru) | 2006-03-10 |
| AU2004216928B2 (en) | 2007-03-08 |
| NZ541951A (en) | 2008-03-28 |
| US7582614B2 (en) | 2009-09-01 |
| WO2004078206A1 (en) | 2004-09-16 |
| MXPA05009526A (es) | 2005-12-15 |
| EP1601376A1 (en) | 2005-12-07 |
| JP2006519789A (ja) | 2006-08-31 |
| AU2004216928C1 (en) | 2007-03-08 |
| JP2011157399A (ja) | 2011-08-18 |
| JP4800924B2 (ja) | 2011-10-26 |
| US8227440B2 (en) | 2012-07-24 |
| AU2004216928A1 (en) | 2004-09-16 |
| US20090317362A1 (en) | 2009-12-24 |
| CA2517147A1 (en) | 2004-09-16 |
| KR20050111349A (ko) | 2005-11-24 |
| US20060263333A1 (en) | 2006-11-23 |
| KR101116858B1 (ko) | 2012-03-06 |
| RU2362584C2 (ru) | 2009-07-27 |
| IL170601A (en) | 2010-11-30 |
| HK1081099A1 (en) | 2006-05-12 |
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| MKLA | Lapsed |
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