JP2012517427A5 - - Google Patents
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- Publication number
- JP2012517427A5 JP2012517427A5 JP2011549167A JP2011549167A JP2012517427A5 JP 2012517427 A5 JP2012517427 A5 JP 2012517427A5 JP 2011549167 A JP2011549167 A JP 2011549167A JP 2011549167 A JP2011549167 A JP 2011549167A JP 2012517427 A5 JP2012517427 A5 JP 2012517427A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- lung cancer
- cell type
- azacytidine
- small cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15147909P | 2009-02-10 | 2009-02-10 | |
| US61/151,479 | 2009-02-10 | ||
| PCT/US2010/000361 WO2010093435A1 (en) | 2009-02-10 | 2010-02-09 | Methods for treating non-small cell lung cancer using 5-azacytidine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015032530A Division JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012517427A JP2012517427A (ja) | 2012-08-02 |
| JP2012517427A5 true JP2012517427A5 (enExample) | 2013-03-21 |
| JP6063628B2 JP6063628B2 (ja) | 2017-01-18 |
Family
ID=42115561
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011549167A Active JP6063628B2 (ja) | 2009-02-10 | 2010-02-09 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
| JP2015032530A Pending JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015032530A Pending JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8492361B2 (enExample) |
| EP (1) | EP2396007A1 (enExample) |
| JP (2) | JP6063628B2 (enExample) |
| CA (1) | CA2789365A1 (enExample) |
| WO (1) | WO2010093435A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6063628B2 (ja) | 2009-02-10 | 2017-01-18 | セルジーン インターナショナル サルル | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
| WO2013022872A1 (en) | 2011-08-10 | 2013-02-14 | Celgene Corporation | Gene methylation biomarkers and methods of use thereof |
| CN104039330A (zh) | 2011-09-26 | 2014-09-10 | 细胞基因公司 | 化疗耐药性的癌症的联合治疗 |
| TW201700103A (zh) | 2011-11-01 | 2017-01-01 | 西建公司 | 利用胞嘧啶核苷類似物之口服配方治療癌症的方法 |
| JP6114317B2 (ja) * | 2012-02-24 | 2017-04-12 | シグナル ファーマシューティカルズ，エルエルシー | Ｔｏｒキナーゼ阻害剤の組合せ療法を用いて、非小細胞肺がんを処置する方法 |
| AU2014254059B2 (en) * | 2013-04-17 | 2019-06-06 | Signal Pharmaceuticals, Llc | Combination therapy comprising a TOR kinase inhibitor and a cytidine analog for treating cancer |
| WO2014180996A1 (en) * | 2013-05-10 | 2014-11-13 | Embl | Use of 5-azacytidine to inhibit nonsense-mediated rna decay (nmd) |
| JP6783224B2 (ja) | 2014-04-04 | 2020-11-11 | デル マー ファーマシューティカルズ | 肺の非小細胞癌腫及び卵巣癌を処置するためのジアンヒドロガラクチトール及びその類縁体又は誘導体の使用 |
| EP3131552B1 (en) | 2014-04-16 | 2020-07-15 | Signal Pharmaceuticals, LLC | Methods for treating cancer using tor kinase inhibitor combination therapy |
| US9718824B2 (en) | 2014-04-16 | 2017-08-01 | Signal Pharmaceuticals, Llc | Solid forms comprising 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, and a coformer, compositions and methods of use thereof |
| WO2015195786A2 (en) * | 2014-06-17 | 2015-12-23 | Celgene Corporation | Methods for treating cancers using oral formulations of cytidine analogs |
| AU2015315435A1 (en) * | 2014-09-08 | 2017-03-23 | Celgene Corporation | Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-PD1 or anti-PDL1 monoclonal antibody |
| US9801983B2 (en) | 2014-12-18 | 2017-10-31 | Cook Medical Technologies Llc | Medical devices for delivering a bioactive to a point of treatment and methods of making medical devices |
| WO2016201337A1 (en) * | 2015-06-12 | 2016-12-15 | Immungene, Inc. | Engineered antibody-interferon fusion molecules for the treatment of glucose-regulated protein 94 (grp94) expressing cancers |
| CA3007357C (en) | 2015-12-03 | 2023-12-05 | Epidestiny, Inc. | Compositions containing decitabine, 5azacytidine and tetrahydrouridine and uses thereof |
| ES2959860T3 (es) | 2017-06-22 | 2024-02-28 | Celgene Corp | Tratamiento del carcinoma hepatocelular caracterizado por la infección por el virus de la hepatitis B |
| JP7017638B2 (ja) | 2018-02-07 | 2022-02-08 | ラブレス バイオメディカル リサーチ インスティテュート | 吸入可能な乾燥粉末シチジン類似体組成物及び癌への治療として使用する方法 |
| US10632211B2 (en) | 2018-06-11 | 2020-04-28 | The Regents Of The University Of California | Demethylation to treat eye disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060063735A1 (en) * | 2004-09-17 | 2006-03-23 | Supergen, Inc. | Salts of 5-azacytidine |
| CA2742252A1 (en) | 2007-11-01 | 2009-05-07 | Celgene Corporation | Cytidine analogs for treatment of myelodysplastic syndromes |
| HUE055911T2 (hu) | 2008-05-15 | 2021-12-28 | Celgene Corp | Citidin-analógokat tartalmazó orális készítmények, és eljárások azok alkalmazására |
| JP6063628B2 (ja) | 2009-02-10 | 2017-01-18 | セルジーン インターナショナル サルル | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
| WO2013022872A1 (en) | 2011-08-10 | 2013-02-14 | Celgene Corporation | Gene methylation biomarkers and methods of use thereof |
-
2010
- 2010-02-09 JP JP2011549167A patent/JP6063628B2/ja active Active
- 2010-02-09 WO PCT/US2010/000361 patent/WO2010093435A1/en not_active Ceased
- 2010-02-09 EP EP10704434A patent/EP2396007A1/en not_active Withdrawn
- 2010-02-09 CA CA2789365A patent/CA2789365A1/en not_active Abandoned
- 2010-02-09 US US13/148,636 patent/US8492361B2/en active Active
-
2013
- 2013-06-07 US US13/913,248 patent/US8841277B2/en not_active Expired - Fee Related
-
2015
- 2015-02-23 JP JP2015032530A patent/JP2015131822A/ja active Pending
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