JP2012517427A5 - - Google Patents
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- Publication number
- JP2012517427A5 JP2012517427A5 JP2011549167A JP2011549167A JP2012517427A5 JP 2012517427 A5 JP2012517427 A5 JP 2012517427A5 JP 2011549167 A JP2011549167 A JP 2011549167A JP 2011549167 A JP2011549167 A JP 2011549167A JP 2012517427 A5 JP2012517427 A5 JP 2012517427A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- lung cancer
- cell type
- azacytidine
- small cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15147909P | 2009-02-10 | 2009-02-10 | |
| US61/151,479 | 2009-02-10 | ||
| PCT/US2010/000361 WO2010093435A1 (en) | 2009-02-10 | 2010-02-09 | Methods for treating non-small cell lung cancer using 5-azacytidine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015032530A Division JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012517427A JP2012517427A (ja) | 2012-08-02 |
| JP2012517427A5 true JP2012517427A5 (enExample) | 2013-03-21 |
| JP6063628B2 JP6063628B2 (ja) | 2017-01-18 |
Family
ID=42115561
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011549167A Active JP6063628B2 (ja) | 2009-02-10 | 2010-02-09 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
| JP2015032530A Pending JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015032530A Pending JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8492361B2 (enExample) |
| EP (1) | EP2396007A1 (enExample) |
| JP (2) | JP6063628B2 (enExample) |
| CA (1) | CA2789365A1 (enExample) |
| WO (1) | WO2010093435A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8492361B2 (en) | 2009-02-10 | 2013-07-23 | Celgene Corporation | Methods for treating non-small cell lung cancer using 5-azacytidine |
| WO2013022872A1 (en) | 2011-08-10 | 2013-02-14 | Celgene Corporation | Gene methylation biomarkers and methods of use thereof |
| WO2013049093A1 (en) | 2011-09-26 | 2013-04-04 | Celgene Corporation | Combination therapy for chemoresistant cancers |
| SG11201401946QA (en) | 2011-11-01 | 2014-05-29 | Celgene Corp | Methods for treating cancers using oral formulations of cytidine analogs |
| CA2864905A1 (en) * | 2012-02-24 | 2013-08-29 | Signal Pharmaceuticals, Llc | Methods for treating non- small cell lung cancer using tor kinase inhibitor combination therapy |
| WO2014172432A1 (en) * | 2013-04-17 | 2014-10-23 | Signal Pharmaceuticals, Llc | Combination therapy comprising a tor kinase inhibitor and a cytidine analog for treating cancer |
| WO2014180996A1 (en) * | 2013-05-10 | 2014-11-13 | Embl | Use of 5-azacytidine to inhibit nonsense-mediated rna decay (nmd) |
| AU2015240465B2 (en) | 2014-04-04 | 2020-02-27 | Del Mar Pharmaceuticals | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer |
| US9718824B2 (en) | 2014-04-16 | 2017-08-01 | Signal Pharmaceuticals, Llc | Solid forms comprising 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, and a coformer, compositions and methods of use thereof |
| US9737535B2 (en) | 2014-04-16 | 2017-08-22 | Signal Pharmaceuticals, Llc | Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines |
| WO2015195786A2 (en) * | 2014-06-17 | 2015-12-23 | Celgene Corporation | Methods for treating cancers using oral formulations of cytidine analogs |
| WO2016040238A1 (en) * | 2014-09-08 | 2016-03-17 | Celgene Corporation | Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-pd1 or anti-pdl1 monoclonal antibody |
| US9801983B2 (en) | 2014-12-18 | 2017-10-31 | Cook Medical Technologies Llc | Medical devices for delivering a bioactive to a point of treatment and methods of making medical devices |
| WO2016201337A1 (en) * | 2015-06-12 | 2016-12-15 | Immungene, Inc. | Engineered antibody-interferon fusion molecules for the treatment of glucose-regulated protein 94 (grp94) expressing cancers |
| CA3007357C (en) | 2015-12-03 | 2023-12-05 | Epidestiny, Inc. | Compositions containing decitabine, 5azacytidine and tetrahydrouridine and uses thereof |
| MY198676A (en) | 2017-06-22 | 2023-09-15 | Celgene Corp | Treatment of hepatocellular carcinoma characterized by hepatitis b virus infection |
| CA3211506A1 (en) | 2018-02-07 | 2019-08-15 | Lovelace Biomedical Research Institute | Inhalable dry powder cytidine analogue composition and method of use as a treatment for cancer |
| CN116059404A (zh) | 2018-06-11 | 2023-05-05 | 加利福尼亚大学董事会 | 用以治疗眼睛疾病的脱甲基化 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060063735A1 (en) * | 2004-09-17 | 2006-03-23 | Supergen, Inc. | Salts of 5-azacytidine |
| JP2011505336A (ja) | 2007-11-01 | 2011-02-24 | セルジーン コーポレイション | 骨髄異形成症候群治療のためのシチジンアナログ |
| MY161593A (en) | 2008-05-15 | 2017-04-28 | Celgene Corp | Oral formulations of cytidine analogs and methods of use thereof |
| US8492361B2 (en) | 2009-02-10 | 2013-07-23 | Celgene Corporation | Methods for treating non-small cell lung cancer using 5-azacytidine |
| WO2013022872A1 (en) | 2011-08-10 | 2013-02-14 | Celgene Corporation | Gene methylation biomarkers and methods of use thereof |
-
2010
- 2010-02-09 US US13/148,636 patent/US8492361B2/en active Active
- 2010-02-09 EP EP10704434A patent/EP2396007A1/en not_active Withdrawn
- 2010-02-09 WO PCT/US2010/000361 patent/WO2010093435A1/en not_active Ceased
- 2010-02-09 JP JP2011549167A patent/JP6063628B2/ja active Active
- 2010-02-09 CA CA2789365A patent/CA2789365A1/en not_active Abandoned
-
2013
- 2013-06-07 US US13/913,248 patent/US8841277B2/en not_active Expired - Fee Related
-
2015
- 2015-02-23 JP JP2015032530A patent/JP2015131822A/ja active Pending
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