JP2011500650A5 - - Google Patents
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- Publication number
- JP2011500650A5 JP2011500650A5 JP2010529411A JP2010529411A JP2011500650A5 JP 2011500650 A5 JP2011500650 A5 JP 2011500650A5 JP 2010529411 A JP2010529411 A JP 2010529411A JP 2010529411 A JP2010529411 A JP 2010529411A JP 2011500650 A5 JP2011500650 A5 JP 2011500650A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- aplidine
- cancer
- gemcitabine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98146307P | 2007-10-19 | 2007-10-19 | |
| PCT/EP2008/064117 WO2009050296A1 (en) | 2007-10-19 | 2008-10-20 | Improved antitumoral treatments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011500650A JP2011500650A (ja) | 2011-01-06 |
| JP2011500650A5 true JP2011500650A5 (enExample) | 2011-12-08 |
Family
ID=40097474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529411A Pending JP2011500650A (ja) | 2007-10-19 | 2008-10-20 | 改良された抗腫瘍治療 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100240595A1 (enExample) |
| EP (1) | EP2205263A1 (enExample) |
| JP (1) | JP2011500650A (enExample) |
| AU (1) | AU2008313627A1 (enExample) |
| CA (1) | CA2703024A1 (enExample) |
| WO (1) | WO2009050296A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE363910T1 (de) * | 1999-11-15 | 2007-06-15 | Pharma Mar Sa | Behandlung von krebserkrankungen durch aplidin |
| PT2029155E (pt) * | 2006-02-28 | 2016-06-17 | Pharma Mar Sa | Tratamento melhorado de mieloma múltiplo |
| US20110009335A1 (en) * | 2008-03-07 | 2011-01-13 | Pharma Mar, S.A. | Anticancer Treatments |
| JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4950649A (en) * | 1980-09-12 | 1990-08-21 | University Of Illinois | Didemnins and nordidemnins |
| US4493796A (en) * | 1980-09-12 | 1985-01-15 | Board Of Trustees, Univ. Of Ill. | Didemnins A, B, C, and derivatives thereof, as antiviral agents |
| IT1153974B (it) * | 1982-09-23 | 1987-01-21 | Erba Farmitalia | Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento |
| ATE74761T1 (de) * | 1985-09-20 | 1992-05-15 | Cernitin Sa | Verwendung von pflanzenpollenextrakten zur herstellung von das wachstum von tumorzellen hemmenden pharmazeutischen praeparaten und verfahren zu ihrer herstellung. |
| US20030148933A1 (en) * | 1990-10-01 | 2003-08-07 | Pharma Mar S.A. | Derivatives of dehydrodidemnin B |
| GB8922026D0 (en) * | 1989-09-29 | 1989-11-15 | Pharma Mar Sa | Novel anti-viral and cytotoxic agent |
| US5580871A (en) * | 1992-11-20 | 1996-12-03 | The Dupont Merck Pharmaceutical Company | 4-Heteroaryl- 1,4-dihydropyridine compounds with calcium agonist and alpha1 -antagonist activity |
| US5462726A (en) * | 1993-12-17 | 1995-10-31 | Bristol-Myers Squibb Company | Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents |
| US6156724A (en) * | 1996-06-07 | 2000-12-05 | Rinehart; Kenneth L. | Uses of didemnins as immunomodulating agents |
| US6034058A (en) * | 1997-04-15 | 2000-03-07 | Rinehart; Kenneth L. | Semi-synthetic alanyl dilemnin analogs |
| EP0981352B8 (en) * | 1997-05-07 | 2009-06-17 | Pharma Mar, S.A. | Use of aplidine for the treatment of cardiovascular diseases |
| US6245759B1 (en) * | 1999-03-11 | 2001-06-12 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| ATE363910T1 (de) * | 1999-11-15 | 2007-06-15 | Pharma Mar Sa | Behandlung von krebserkrankungen durch aplidin |
| US6509315B1 (en) * | 2000-04-07 | 2003-01-21 | The Trustees Of The University Of Pennsylvania | Didemnin analogs and fragments and methods of making and using them |
| ATE339963T1 (de) * | 2000-04-07 | 2006-10-15 | Univ Pennsylvania | Tamandarin und didemnin analoga und methoden zu deren herstellung und verwendung |
| UA76718C2 (uk) * | 2000-06-30 | 2006-09-15 | Фарма Мар, С.А. | Протипухлинні похідні аплідину |
| ATE299028T1 (de) * | 2000-10-12 | 2005-07-15 | Pharma Mar Sa | Behandlung von krebserkrankungen mit aplidin in kombination mit carnitin oder acetylcarnitin |
| ATE411036T1 (de) * | 2001-10-19 | 2008-10-15 | Pharma Mar Sa | Verwendung von aplidine in der behandlung von pankreaskrebs |
| WO2004080477A1 (en) * | 2003-03-12 | 2004-09-23 | Dana-Farber Cancer Institute, Inc. | Aplidine for multiple myeloma treatment |
| AU2004220451B2 (en) * | 2003-03-12 | 2010-01-21 | Pharma Mar, S.A. | Improved antitumoral treatments |
| CA2519234A1 (en) * | 2003-03-21 | 2004-10-07 | Madeleine M. Joullie | Tamandarin analogs and fragments thereof and methods of making and using |
| PT2029155E (pt) * | 2006-02-28 | 2016-06-17 | Pharma Mar Sa | Tratamento melhorado de mieloma múltiplo |
-
2008
- 2008-10-20 EP EP08840135A patent/EP2205263A1/en not_active Withdrawn
- 2008-10-20 AU AU2008313627A patent/AU2008313627A1/en not_active Abandoned
- 2008-10-20 JP JP2010529411A patent/JP2011500650A/ja active Pending
- 2008-10-20 US US12/682,910 patent/US20100240595A1/en not_active Abandoned
- 2008-10-20 WO PCT/EP2008/064117 patent/WO2009050296A1/en not_active Ceased
- 2008-10-20 CA CA2703024A patent/CA2703024A1/en not_active Abandoned
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