AU2008313627A1 - Improved antitumoral treatments - Google Patents

Improved antitumoral treatments Download PDF

Info

Publication number
AU2008313627A1
AU2008313627A1 AU2008313627A AU2008313627A AU2008313627A1 AU 2008313627 A1 AU2008313627 A1 AU 2008313627A1 AU 2008313627 A AU2008313627 A AU 2008313627A AU 2008313627 A AU2008313627 A AU 2008313627A AU 2008313627 A1 AU2008313627 A1 AU 2008313627A1
Authority
AU
Australia
Prior art keywords
acceptable salt
pharmaceutically acceptable
aplidine
gemcitabine
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008313627A
Other languages
English (en)
Inventor
Debabrata Banerjee
Joseph Rocco Bertino
Prasun Jaiprakash Mishra
Pravin Jaiprakash Mishra
Jose Maria Jimeno Donaque
Giuseppe Longo Sorbello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmamar SA
Original Assignee
Pharmamar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmamar SA filed Critical Pharmamar SA
Publication of AU2008313627A1 publication Critical patent/AU2008313627A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15Depsipeptides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2008313627A 2007-10-19 2008-10-20 Improved antitumoral treatments Abandoned AU2008313627A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98146307P 2007-10-19 2007-10-19
US60/981,463 2007-10-19
PCT/EP2008/064117 WO2009050296A1 (en) 2007-10-19 2008-10-20 Improved antitumoral treatments

Publications (1)

Publication Number Publication Date
AU2008313627A1 true AU2008313627A1 (en) 2009-04-23

Family

ID=40097474

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008313627A Abandoned AU2008313627A1 (en) 2007-10-19 2008-10-20 Improved antitumoral treatments

Country Status (6)

Country Link
US (1) US20100240595A1 (enExample)
EP (1) EP2205263A1 (enExample)
JP (1) JP2011500650A (enExample)
AU (1) AU2008313627A1 (enExample)
CA (1) CA2703024A1 (enExample)
WO (1) WO2009050296A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK287762B6 (sk) * 1999-11-15 2011-09-05 Pharma Mar, S. A. Použitie aplidínu na prípravu farmaceutického prostriedku na liečenie rakoviny
KR20140101014A (ko) * 2006-02-28 2014-08-18 파르마 마르 에스.에이. 개선된 항종양 치료
EP2262523A1 (en) * 2008-03-07 2010-12-22 Pharma Mar S.A. Improved anticancer treatments
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493796A (en) * 1980-09-12 1985-01-15 Board Of Trustees, Univ. Of Ill. Didemnins A, B, C, and derivatives thereof, as antiviral agents
US4950649A (en) * 1980-09-12 1990-08-21 University Of Illinois Didemnins and nordidemnins
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
ATE74761T1 (de) * 1985-09-20 1992-05-15 Cernitin Sa Verwendung von pflanzenpollenextrakten zur herstellung von das wachstum von tumorzellen hemmenden pharmazeutischen praeparaten und verfahren zu ihrer herstellung.
GB8922026D0 (en) * 1989-09-29 1989-11-15 Pharma Mar Sa Novel anti-viral and cytotoxic agent
US20030148933A1 (en) * 1990-10-01 2003-08-07 Pharma Mar S.A. Derivatives of dehydrodidemnin B
US5580871A (en) * 1992-11-20 1996-12-03 The Dupont Merck Pharmaceutical Company 4-Heteroaryl- 1,4-dihydropyridine compounds with calcium agonist and alpha1 -antagonist activity
US5462726A (en) * 1993-12-17 1995-10-31 Bristol-Myers Squibb Company Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents
US6156724A (en) * 1996-06-07 2000-12-05 Rinehart; Kenneth L. Uses of didemnins as immunomodulating agents
US6034058A (en) * 1997-04-15 2000-03-07 Rinehart; Kenneth L. Semi-synthetic alanyl dilemnin analogs
AU740598B2 (en) * 1997-05-07 2001-11-08 William J. Crumb Aplidine as an L-type calcium channel enhancer
US6245759B1 (en) * 1999-03-11 2001-06-12 Merck & Co., Inc. Tyrosine kinase inhibitors
SK287762B6 (sk) * 1999-11-15 2011-09-05 Pharma Mar, S. A. Použitie aplidínu na prípravu farmaceutického prostriedku na liečenie rakoviny
BR0109958A (pt) * 2000-04-07 2003-05-27 Univ Pennsylvania Análogos de didemnina e tamandarina e métodos de preparação e uso deles
US6509315B1 (en) * 2000-04-07 2003-01-21 The Trustees Of The University Of Pennsylvania Didemnin analogs and fragments and methods of making and using them
UA76718C2 (uk) * 2000-06-30 2006-09-15 Фарма Мар, С.А. Протипухлинні похідні аплідину
HK1054191A1 (zh) * 2000-10-12 2003-11-21 Pharma Mar, S.A. 施用aplidine時同時使用myoprotector的癌症治療
AU2002336206B2 (en) * 2001-10-19 2007-11-29 Pharma Mar, S.A. Use of aplidine for the treatment of pancreatic cancer
WO2004080477A1 (en) * 2003-03-12 2004-09-23 Dana-Farber Cancer Institute, Inc. Aplidine for multiple myeloma treatment
JP2006519848A (ja) * 2003-03-12 2006-08-31 ファルマ・マール・ソシエダード・アノニマ 改良された抗腫瘍治療
US8030279B2 (en) * 2003-03-21 2011-10-04 The Trustees Of The University Of Pennsylvania Tamandarin analogs and fragments thereof and methods of making and using
KR20140101014A (ko) * 2006-02-28 2014-08-18 파르마 마르 에스.에이. 개선된 항종양 치료

Also Published As

Publication number Publication date
CA2703024A1 (en) 2009-04-23
WO2009050296A1 (en) 2009-04-23
EP2205263A1 (en) 2010-07-14
JP2011500650A (ja) 2011-01-06
US20100240595A1 (en) 2010-09-23

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period