JP2014523238A - インターフェロンと標的化修飾ユビキチンタンパク質とを含むヒト融合タンパク質 - Google Patents
インターフェロンと標的化修飾ユビキチンタンパク質とを含むヒト融合タンパク質 Download PDFInfo
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/52—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07—ORGANIC CHEMISTRY
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Landscapes
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| PCT/EP2011/002962 WO2012171541A1 (en) | 2011-06-15 | 2011-06-15 | Human fusion proteins comprising interferons and hetero-dimeric modified ubiquitin proteins |
| PCT/EP2012/061459 WO2012172058A1 (en) | 2011-06-15 | 2012-06-15 | Human fusion proteins comprising interferons and targeted modified ubiquitin proteins |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2022528053A (ja) * | 2019-04-10 | 2022-06-08 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | がん診断及び治療のための新規ｐｓｍａ特異的結合タンパク質 |
| WO2023239213A1 (ko) * | 2022-06-10 | 2023-12-14 | 주식회사 쎌트로이 | 염증세포에서 특이적으로 작동하는 융합단백질 |
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| DK2721152T3 (da) | 2011-06-15 | 2019-07-01 | Navigo Proteins Gmbh | Dimere bindingsproteiner baseret på modificerede ubiquitiner |
| WO2014094799A1 (en) * | 2012-12-19 | 2014-06-26 | Scil-Proteins-Gmbh | Ubiquitin moieties as a means for prolonging serum half-life |
| EP3253785B1 (en) | 2015-02-06 | 2019-04-10 | Navigo Proteins Gmbh | Novel egfr binding proteins |
| DK3322721T3 (da) | 2015-07-16 | 2022-03-14 | Navigo Proteins Gmbh | Nye immunglobulin-bindende proteiner og deres anvendelse i affinitetsoprensning |
| JP2018520675A (ja) | 2015-07-20 | 2018-08-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法 |
| AU2017260274A1 (en) | 2016-05-04 | 2018-11-01 | Navigo Proteins Gmbh | Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker |
| US11230576B2 (en) | 2016-08-11 | 2022-01-25 | Navigo Proteins Gmbh | Alkaline stable immunoglobulin-binding proteins |
| KR102945203B1 (ko) | 2017-05-08 | 2026-03-31 | 시애틀 프로젝트 코포레이션 | 알파바이러스 신생항원 벡터 |
| WO2019091918A1 (en) | 2017-11-07 | 2019-05-16 | Navigo Proteins Gmbh | Fusion proteins with specificity for ed-b and long serum half-life for diagnosis or treatment of cancer |
| KR20240134250A (ko) | 2018-01-04 | 2024-09-06 | 아이코닉 테라퓨틱스, 인코포레이티드 | 항-조직 인자 항체, 항체-약물 결합체, 및 관련 방법 |
| US20200339639A1 (en) * | 2018-01-11 | 2020-10-29 | Uti Limited Partnership | Treatment of fragile x syndrome |
| CN108727504B (zh) * | 2018-04-16 | 2021-08-27 | 泉州向日葵生物科技有限公司 | 一种ifn与抗pd-l1抗体的融合蛋白及其应用 |
| KR20210090650A (ko) | 2018-11-07 | 2021-07-20 | 그릿스톤 바이오, 인코포레이티드 | 알파바이러스 신생항원 벡터 및 인터페론 억제제 |
| KR20210104106A (ko) | 2018-12-18 | 2021-08-24 | 나피고 프로타인스 게엠베하 | 암 진단 및 치료를 위한 신규 folr1 특이적 결합 단백질 |
| SG11202113187WA (en) | 2019-05-30 | 2021-12-30 | Gritstone Bio Inc | Modified adenoviruses |
| EP4139343A4 (en) * | 2020-04-20 | 2024-06-12 | National Research Council of Canada | RECOMBINANT INTERFERON |
| US20240043492A1 (en) * | 2020-04-25 | 2024-02-08 | East Carolina University | Compositions and Methods of Treating a Coronavirus Infection By Use of an Interferon Fusion Protein |
| IL300026A (en) | 2020-08-06 | 2023-03-01 | Gritstone Bio Inc | Multiepitope vaccine cassettes |
| US20240190935A1 (en) * | 2021-04-26 | 2024-06-13 | East Carolina University | Compositions and methods of treating pathogenic infections by using fusion proteins |
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| JP2003523406A (ja) * | 2000-02-24 | 2003-08-05 | フィロジェン ソチエタ レスポンサビリタ リミテ | 病理学的病変における脈管形成の処理のための組成物及び方法 |
| JP2008500953A (ja) * | 2003-05-28 | 2008-01-17 | サイル プロテインズ ゲーエムベーハー | ユビキチンタンパク質に基づく人工結合タンパク質の生成 |
| WO2009126558A1 (en) * | 2008-04-10 | 2009-10-15 | Ibc Pharmaceuticals, Inc. | Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (dnl) technology |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2022528053A (ja) * | 2019-04-10 | 2022-06-08 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | がん診断及び治療のための新規ｐｓｍａ特異的結合タンパク質 |
| JP7498971B2 (ja) | 2019-04-10 | 2024-06-13 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | がん診断及び治療のための新規ｐｓｍａ特異的結合タンパク質 |
| WO2023239213A1 (ko) * | 2022-06-10 | 2023-12-14 | 주식회사 쎌트로이 | 염증세포에서 특이적으로 작동하는 융합단백질 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL229723A0 (en) | 2014-01-30 |
| WO2012171541A1 (en) | 2012-12-20 |
| WO2012172058A1 (en) | 2012-12-20 |
| CA2837875A1 (en) | 2012-12-20 |
| US20140219959A1 (en) | 2014-08-07 |
| AU2012268973A1 (en) | 2013-12-12 |
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