JP2014521661A5 - - Google Patents
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- JP2014521661A5 JP2014521661A5 JP2014523099A JP2014523099A JP2014521661A5 JP 2014521661 A5 JP2014521661 A5 JP 2014521661A5 JP 2014523099 A JP2014523099 A JP 2014523099A JP 2014523099 A JP2014523099 A JP 2014523099A JP 2014521661 A5 JP2014521661 A5 JP 2014521661A5
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- JP
- Japan
- Prior art keywords
- tissue
- molecule
- amino acid
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- kda
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161513287P | 2011-07-29 | 2011-07-29 | |
| US61/513,287 | 2011-07-29 | ||
| PCT/US2012/048732 WO2013019681A2 (en) | 2011-07-29 | 2012-07-27 | Selective delivery molecules and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014521661A JP2014521661A (ja) | 2014-08-28 |
| JP2014521661A5 true JP2014521661A5 (https=) | 2015-08-13 |
| JP6124150B2 JP6124150B2 (ja) | 2017-05-10 |
Family
ID=47629864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014523099A Expired - Fee Related JP6124150B2 (ja) | 2011-07-29 | 2012-07-27 | 選択的な送達分子及び使用方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (6) | US9278144B2 (https=) |
| EP (2) | EP2736533B1 (https=) |
| JP (1) | JP6124150B2 (https=) |
| KR (1) | KR102004558B1 (https=) |
| CN (1) | CN103874512B (https=) |
| AU (1) | AU2012290318B2 (https=) |
| CA (1) | CA2841249C (https=) |
| DK (1) | DK2736533T3 (https=) |
| EA (1) | EA030795B1 (https=) |
| ES (1) | ES2683377T3 (https=) |
| MX (1) | MX350082B (https=) |
| WO (1) | WO2013019681A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9695251B2 (en) | 2003-10-31 | 2017-07-04 | The Regents Of The University Of California | Activatable cell penetrating peptides with quenched fluorophores |
| US7985401B2 (en) | 2003-10-31 | 2011-07-26 | The Regents Of The University Of California | Peptides whose uptake by cells is controllable |
| ES2890501T3 (es) | 2009-03-02 | 2022-01-20 | Massachusetts Inst Technology | Métodos y productos para la creación de perfiles enzimáticos in vivo |
| JP2012533560A (ja) | 2009-07-15 | 2012-12-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 細胞における取り込みが制御可能なペプチド |
| MX350082B (es) | 2011-07-29 | 2017-08-24 | Avelas Biosciences Inc | Moleculas de entrega selectiva y metodos de uso. |
| WO2014120837A2 (en) * | 2013-01-29 | 2014-08-07 | The Regents Of The University Of California | Pretargeted activatable cell penetrating peptide with intracellulary releaseable prodrug |
| AU2014212308B2 (en) * | 2013-01-30 | 2018-08-09 | Avelas Biosciences, Inc. | Selective delivery molecules and methods of use |
| WO2014176284A1 (en) * | 2013-04-22 | 2014-10-30 | Avelas Biosciences, Inc. | Selective drug delivery compositions and methods of use |
| PL405046A1 (pl) * | 2013-08-12 | 2015-02-16 | Instytut Biologii Doświadczalnej Im. Marcelego Nenckiego Pan | Genetycznie kodowany oparty na FRET biosensor aktywności MMP-9 i jego zastosowanie |
| US10385380B2 (en) | 2014-10-02 | 2019-08-20 | The Regents Of The University Of California | Personalized protease assay to measure protease activity in neoplasms |
| US10596259B2 (en) | 2015-05-20 | 2020-03-24 | The Regents Of The University Of California | Tumor radiosensitization with monomethyl auristatin E (MMAE) and derivatives thereof |
| WO2017211278A1 (en) * | 2016-06-06 | 2017-12-14 | Asclepiumm Taiwan Co., Ltd | Antibody fusion proteins for drug delivery |
| WO2018187629A1 (en) * | 2017-04-07 | 2018-10-11 | Avelas Biosciences, Inc. | Ratiometric fluorescence imaging methods |
| US10450119B2 (en) * | 2017-06-22 | 2019-10-22 | The Procter & Gamble Company | Films including a water-soluble layer and a vapor-deposited inorganic coating |
| EP3641951B1 (en) | 2017-06-22 | 2023-09-20 | The Procter & Gamble Company | Films including a water-soluble layer and a vapor-deposited organic coating |
| CN108096255B (zh) * | 2017-12-28 | 2019-11-12 | 北京大学 | 地夫可特用于抑制或治疗胰腺癌的用途 |
| US11054428B2 (en) | 2018-03-05 | 2021-07-06 | Massachusetts Institute Of Technology | Inhalable nanosensors with volatile reporters and uses thereof |
| US20220347306A1 (en) * | 2018-04-16 | 2022-11-03 | Avelas Biosciences, Inc. | Selective delivery of therapeutic and imaging agents |
| EP3856921B1 (en) | 2018-09-25 | 2026-04-29 | Massachusetts Institute Of Technology | Lung protease nanosensors and uses thereof |
| WO2020150560A1 (en) | 2019-01-17 | 2020-07-23 | Massachusetts Institute Of Technology | Sensors for detecting and imaging of cancer metastasis |
| CN110075322B (zh) * | 2019-05-20 | 2021-07-06 | 复旦大学附属妇产科医院 | 一种靶向GnRH受体的近红外荧光成像探针及其制备方法与应用 |
| WO2021061752A1 (en) * | 2019-09-23 | 2021-04-01 | Neonc Technologies, Inc. | Pharmaceutical compositions comprising poh derivatives |
| EP4683668A1 (en) * | 2023-05-05 | 2026-01-28 | The United States Government as Represented by The Department of Veterans Affairs | Compositions and methods for treating tendon and bone injuries |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4466919A (en) | 1982-12-16 | 1984-08-21 | Monsanto Company | Peptide substrates for mammalian collagenase |
| US4507389A (en) | 1982-12-16 | 1985-03-26 | Monsanto Company | Determination of collagenase by reacting with peptide substrates |
| GB8927722D0 (en) | 1989-12-07 | 1990-02-07 | British Bio Technology | Proteins and nucleic acids |
| US5670617A (en) | 1989-12-21 | 1997-09-23 | Biogen Inc | Nucleic acid conjugates of tat-derived transport polypeptides |
| US5789555A (en) * | 1993-11-16 | 1998-08-04 | Resolution Pharmaceuticals Inc. | Immobilized labelling method |
| US6083486A (en) | 1998-05-14 | 2000-07-04 | The General Hospital Corporation | Intramolecularly-quenched near infrared fluorescent probes |
| US6592847B1 (en) | 1998-05-14 | 2003-07-15 | The General Hospital Corporation | Intramolecularly-quenched near infrared flourescent probes |
| CA2328457A1 (en) | 1998-06-20 | 1999-12-29 | Washington University | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
| US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| US20020009786A1 (en) | 2000-04-18 | 2002-01-24 | Tang Y. Tom | Novel nucleic acids and polypeptides |
| WO2003006043A1 (en) | 2001-07-10 | 2003-01-23 | Massachusetts Institute Of Technology | Surfactant peptide nanostructures, and uses thereof |
| US7371364B2 (en) | 2003-08-15 | 2008-05-13 | Board Of Regents, The University Of Texas System | Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy |
| US9695251B2 (en) | 2003-10-31 | 2017-07-04 | The Regents Of The University Of California | Activatable cell penetrating peptides with quenched fluorophores |
| US7431915B2 (en) | 2003-10-31 | 2008-10-07 | The Regents Of The University Of California | Peptides whose uptake by cells is controllable |
| US7985401B2 (en) * | 2003-10-31 | 2011-07-26 | The Regents Of The University Of California | Peptides whose uptake by cells is controllable |
| US7498298B2 (en) | 2003-11-06 | 2009-03-03 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
| EP2327724A3 (en) | 2004-02-02 | 2011-07-27 | Ambrx, Inc. | Modified human growth hormone polypeptides and their uses |
| JP2008542784A (ja) * | 2005-06-07 | 2008-11-27 | サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、（セーエヌエルエス） | 組織切片のｍａｌｄｉ質量分析法による分析のためのイオンマトリックスの使用 |
| NZ586947A (en) | 2008-02-08 | 2012-11-30 | Ambrx Inc | Modified leptin polypeptides and their uses |
| TW201004647A (en) | 2008-05-20 | 2010-02-01 | Sigma Tau Ind Farmaceuti | Novel dual targeting antitumoural conjugates |
| WO2010014236A2 (en) * | 2008-07-30 | 2010-02-04 | The University Of North Carolina At Chapel Hill | Acylhydrazone-based cleavable linkers |
| EP2344134B1 (en) | 2008-09-23 | 2017-11-08 | The Regents of The University of California | Nanocarriers for drug delivery |
| MX2011003272A (es) | 2008-09-26 | 2011-04-28 | Ambrx Inc | Polipeptidos de eritropoyetina animal modificados y sus usos. |
| KR101095841B1 (ko) | 2009-02-19 | 2011-12-21 | 주식회사 나이벡 | 표적 선택적 세포／조직 투과기능 활성을 가지는 펩타이드 및 그 용도 |
| RU2011138096A (ru) | 2009-03-19 | 2013-04-27 | Дженерал Электрик Компани | Агенты для оптической визуализации |
| EP2429565A4 (en) | 2009-04-15 | 2012-11-14 | Univ California | NEURONIC OR NERVE PEPTIDES AND APTAMERS |
| JP2012533560A (ja) | 2009-07-15 | 2012-12-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 細胞における取り込みが制御可能なペプチド |
| US20130142734A1 (en) * | 2010-01-12 | 2013-06-06 | Ayelet David | Targeted delivery systems for diagnostic applications |
| JP5580625B2 (ja) | 2010-03-03 | 2014-08-27 | 住友化学株式会社 | メタンスルホン酸アルキルエステル溶液の製造方法 |
| US20120055055A1 (en) | 2010-09-02 | 2012-03-08 | Illumin8 Outdoor Media, LLC | Systems and Method for Outdoor Media Signage |
| CN103402546B (zh) | 2011-02-10 | 2018-04-13 | 海德堡鲁普雷希特卡尔斯大学 | 用于肝特异性诊断的疏水性修饰肽 |
| MX350082B (es) | 2011-07-29 | 2017-08-24 | Avelas Biosciences Inc | Moleculas de entrega selectiva y metodos de uso. |
| WO2014120837A2 (en) | 2013-01-29 | 2014-08-07 | The Regents Of The University Of California | Pretargeted activatable cell penetrating peptide with intracellulary releaseable prodrug |
| AU2014212308B2 (en) | 2013-01-30 | 2018-08-09 | Avelas Biosciences, Inc. | Selective delivery molecules and methods of use |
| WO2014176284A1 (en) | 2013-04-22 | 2014-10-30 | Avelas Biosciences, Inc. | Selective drug delivery compositions and methods of use |
-
2012
- 2012-07-27 MX MX2014001138A patent/MX350082B/es active IP Right Grant
- 2012-07-27 CN CN201280047936.9A patent/CN103874512B/zh not_active Expired - Fee Related
- 2012-07-27 EA EA201490385A patent/EA030795B1/ru not_active IP Right Cessation
- 2012-07-27 AU AU2012290318A patent/AU2012290318B2/en not_active Ceased
- 2012-07-27 KR KR1020147002685A patent/KR102004558B1/ko not_active Expired - Fee Related
- 2012-07-27 US US14/235,522 patent/US9278144B2/en active Active
- 2012-07-27 EP EP12820320.5A patent/EP2736533B1/en active Active
- 2012-07-27 ES ES12820320.5T patent/ES2683377T3/es active Active
- 2012-07-27 JP JP2014523099A patent/JP6124150B2/ja not_active Expired - Fee Related
- 2012-07-27 EP EP18181420.3A patent/EP3473273A1/en not_active Withdrawn
- 2012-07-27 CA CA2841249A patent/CA2841249C/en active Active
- 2012-07-27 DK DK12820320.5T patent/DK2736533T3/en active
- 2012-07-27 WO PCT/US2012/048732 patent/WO2013019681A2/en not_active Ceased
-
2016
- 2016-01-26 US US15/006,832 patent/US9371367B1/en not_active Expired - Fee Related
- 2016-04-19 US US15/132,773 patent/US9504763B2/en not_active Expired - Fee Related
- 2016-10-17 US US15/295,482 patent/US9840537B2/en not_active Expired - Fee Related
-
2017
- 2017-11-07 US US15/806,246 patent/US10239919B2/en active Active
-
2018
- 2018-12-20 US US16/228,488 patent/US10570178B2/en active Active
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