JP2014518609A - Ｃ１６：１ｎ７−パルミトレアートを含む組成物および方法 - Google Patents

Ｃ１６：１ｎ７−パルミトレアートを含む組成物および方法 Download PDF

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Publication number
JP2014518609A
JP2014518609A JP2013556902A JP2013556902A JP2014518609A JP 2014518609 A JP2014518609 A JP 2014518609A JP 2013556902 A JP2013556902 A JP 2013556902A JP 2013556902 A JP2013556902 A JP 2013556902A JP 2014518609 A JP2014518609 A JP 2014518609A
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derivative
palmitreate
dietary supplement
baseline
compared
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JP2013556902A
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Japanese (ja)
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JP2014518609A5 (enExample
Inventor
ジェフリー グリーン
Original Assignee
テルサス ファーマシューティカルズ リミテッド ライアビリティ カンパニー
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Publication of JP2014518609A publication Critical patent/JP2014518609A/ja
Publication of JP2014518609A5 publication Critical patent/JP2014518609A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2013556902A 2011-03-03 2012-03-02 Ｃ１６：１ｎ７−パルミトレアートを含む組成物および方法 Pending JP2014518609A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161449015P 2011-03-03 2011-03-03
US61/449,015 2011-03-03
PCT/US2012/027489 WO2012119078A2 (en) 2011-03-03 2012-03-02 COMPOSITIONS AND METHODS COMPRISING C16:1n7-PALMITOLEATE

Related Child Applications (1)

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JP2015222558A Division JP6267681B2 (ja) 2011-03-03 2015-11-13 Ｃ１６：１ｎ７−パルミトレアートを含む組成物および方法

Publications (2)

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JP2014518609A true JP2014518609A (ja) 2014-08-07
JP2014518609A5 JP2014518609A5 (enExample) 2015-01-29

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JP2013556902A Pending JP2014518609A (ja) 2011-03-03 2012-03-02 Ｃ１６：１ｎ７−パルミトレアートを含む組成物および方法
JP2015222558A Active JP6267681B2 (ja) 2011-03-03 2015-11-13 Ｃ１６：１ｎ７−パルミトレアートを含む組成物および方法

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Country Status (10)

Country Link
US (6) US8703818B2 (enExample)
EP (2) EP3510998A1 (enExample)
JP (2) JP2014518609A (enExample)
KR (1) KR20140010126A (enExample)
CN (1) CN103889219A (enExample)
AU (5) AU2012223171B2 (enExample)
CA (1) CA2829051C (enExample)
MX (1) MX2013010076A (enExample)
SG (1) SG193258A1 (enExample)
WO (1) WO2012119078A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020182497A (ja) * 2014-10-15 2020-11-12 バーク アンド ボイヤー エヌワイシーＢｕｒｋｅ ＆ Ｂｏｙｅｒ Ｎｙｃ 一価不飽和脂肪酸組成物およびアテローム性動脈硬化症を処置するための使用

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9101942B2 (en) 2009-06-16 2015-08-11 Aurora Algae, Inc. Clarification of suspensions
US9200236B2 (en) 2011-11-17 2015-12-01 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
US10123986B2 (en) 2012-12-24 2018-11-13 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US9629820B2 (en) 2012-12-24 2017-04-25 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US9266973B2 (en) 2013-03-15 2016-02-23 Aurora Algae, Inc. Systems and methods for utilizing and recovering chitosan to process biological material
US20140275613A1 (en) * 2013-03-15 2014-09-18 Aurora Algae, Inc. Conversion of free fatty acids to ethyl esters
WO2015077499A1 (en) 2013-11-22 2015-05-28 Heliae Development, Llc Isolation of omega-7 fatty acid ethyl esters from natural oils
KR102243022B1 (ko) * 2014-03-05 2021-04-21 삼성메디슨 주식회사 선택 정보에 기초하여 관심 영역에 포함된 혈류에 대한 정보를 출력하는 방법, 장치 및 시스템.
WO2015187997A1 (en) 2014-06-04 2015-12-10 Tersus Pharmaceuticals, LLC METHODS OF TREATING CHRONIC DRY EYE DISEASE USING C16:1n7 PALMITOLEATE AND DERIVATIVES THEREOF
EP3166415A4 (en) * 2014-07-08 2017-12-06 Omega Protein Corporation Enrichment of palmitoleic acid palmitoleic acid derivatives by dry and solvent-aided winterization
WO2016011410A1 (en) * 2014-07-17 2016-01-21 Cornell University Omega-3 fatty acid enrichment of poultry products with defatted microalgae animal feed
US10058524B2 (en) 2015-02-18 2018-08-28 Tersus Life Sciences, LLC Methods for improving joint function
IT201600093741A1 (it) * 2016-09-19 2018-03-19 Codex V Srl Insaponificabili di lipidi naturali per l’uso nel trattamento di patologie cardiache
TWI750189B (zh) 2016-12-15 2021-12-21 大陸商深圳瑞健生命科學研究院有限公司 一種治療冠狀動脈粥樣硬化及其併發症的方法
CN108210904A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 治疗动脉粥样硬化及其并发症的药物及其用途
JP7168990B2 (ja) 2016-12-15 2022-11-10 タレンゲン インターナショナル リミテッド 肥満症を予防および治療するための方法および薬物
AU2022248850A1 (en) 2021-03-27 2023-11-09 TRx Biosciences Limited Compositions having improved bioavailability of therapeutics
JP2026011459A (ja) * 2024-07-11 2026-01-23 日油株式会社 パルミトレイン酸を含有する脂肪酸組成物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001200289A (ja) * 1999-12-10 2001-07-24 Unilever Nv パルミトレイン酸及び食品におけるその使用
WO2010049954A1 (en) * 2008-10-31 2010-05-06 Lipid Pharmaceuticals Ehf. Fatty acids for use as a medicament

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4270537A (en) 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
JPS61297A (ja) 1984-06-12 1986-01-06 日本油脂株式会社 オレイン酸の製造法
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
CA1283827C (en) 1986-12-18 1991-05-07 Giorgio Cirelli Appliance for injection of liquid formulations
GB8704027D0 (en) 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US5339163A (en) 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
FR2638359A1 (fr) 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5198250A (en) 1990-07-16 1993-03-30 Lipotech Partners Limited Partnership Food and pharmaceutical compositions containing short chain monounsaturated fatty acids and methods of using
US5190521A (en) 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
SE9102652D0 (sv) 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
US5328483A (en) 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5298637A (en) * 1992-10-22 1994-03-29 Arco Chemical Technology, L.P. Process for producing a reduced calorie lipid composition
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
WO1995024176A1 (en) 1994-03-07 1995-09-14 Bioject, Inc. Ampule filling device
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
EP1106072B1 (en) 1999-12-10 2005-11-30 Loders Croklaan B.V. Palmitoleic acid and its use in foods
US20030064950A1 (en) * 2001-02-23 2003-04-03 Ntambi James M. Methods for reducing body fat and increasing lean body mass by reducing stearoyl-CoA desaturase 1 activity
US6686185B1 (en) * 2000-03-07 2004-02-03 Millennium Pharmaceuticals, Inc. 25934, a novel fatty acid desaturase and uses therefor
AT414205B (de) * 2000-06-20 2006-10-15 Vis Vitalis Lizenz & Handels Verfahren zur herstellung von ungesättigtem fettsäure-trockenkonzentrat
US20040209953A1 (en) * 2002-12-06 2004-10-21 Wai Lee Theresa Siu-Ling Glyceride compositions and methods of making and using same
US20050004218A1 (en) * 2003-05-05 2005-01-06 Bauman Dale E. Vaccenic acid
EP1729851A2 (en) * 2004-03-10 2006-12-13 Natural ASA Compositions comprising reverse isomers of conjugated linoleic acid
JP4931391B2 (ja) * 2004-10-08 2012-05-16 日清オイリオグループ株式会社 不飽和脂肪酸濃縮物の製造方法
US20060088574A1 (en) * 2004-10-25 2006-04-27 Manning Paul B Nutritional supplements
ES2285923B1 (es) 2005-12-14 2008-10-16 Dieta Mediterranea Aceites Y Vinagres, S.A. Producto para su utilizacion en la prevencion y tratamiento de enfermedades cardiovasculares, cancer y enfermedades inflamatorias cronicas.
US20100242345A1 (en) 2006-05-19 2010-09-30 LS9, Inc Production of fatty acids & derivatives thereof
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
JP2008156296A (ja) * 2006-12-25 2008-07-10 Sapporo Breweries Ltd メタボリックシンドローム改善剤
US8110093B2 (en) 2007-03-14 2012-02-07 Ls9, Inc. Process for producing low molecular weight hydrocarbons from renewable resources
US20080293060A1 (en) 2007-04-23 2008-11-27 Ls9, Inc. Methods and Compositions for Identification of Hydrocarbon Response, Transport and Biosynthesis Genes
JP5912251B2 (ja) 2007-05-22 2016-06-01 アールイージー ライフ サイエンシズ リミテッド ライアビリティ カンパニー 炭化水素産生遺伝子およびその使用方法
WO2009009391A2 (en) 2007-07-06 2009-01-15 Ls9, Inc. Systems and methods for the production of fatty esters
WO2009039505A1 (en) * 2007-09-20 2009-03-26 Rutgers, The State University Of New Jersey Compositions and methods for treating cardiovascular conditions
DK2280928T3 (en) * 2008-05-01 2018-11-05 Complexa Inc Vinyl-substituted fatty acids
CN101278743B (zh) * 2008-05-08 2012-01-25 浙江大学城市学院 一种从蚕蛹中提取不饱和脂肪酸的方法
JP2011522525A (ja) 2008-05-16 2011-08-04 エルエス９・インコーポレイテッド 炭化水素を製造するための方法および組成物
WO2010021711A1 (en) 2008-08-18 2010-02-25 Ls9, Inc. Systems and methods for the production of mixed fatty esters
WO2010028336A2 (en) 2008-09-08 2010-03-11 President And Fellows Of Harvard College Fatty acid c16:1n7-palmitoleate a lipokine and biomarker for metabolic status
WO2010062480A2 (en) 2008-10-28 2010-06-03 Ls9, Inc. Methods and compositions for producing fatty alcohols
WO2010118362A1 (en) * 2009-04-09 2010-10-14 The Regents Of The University Of Colorado, A Body Corporate Methods and compositions for inducing physiological hypertrophy
CA2758298A1 (en) 2009-04-10 2010-10-14 Ls9, Inc. Production of commercial biodiesel from genetically modified microorganisms
BRPI1015313B1 (pt) 2009-04-27 2021-06-01 Genomatica, Inc. Método fermentativo para produzir um éster de ácido graxo empregando um microorganismo geneticamente modificado e método para a produção de ésteres de ácidos graxos

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001200289A (ja) * 1999-12-10 2001-07-24 Unilever Nv パルミトレイン酸及び食品におけるその使用
WO2010049954A1 (en) * 2008-10-31 2010-05-06 Lipid Pharmaceuticals Ehf. Fatty acids for use as a medicament

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6015000747; 生活衛生，　１９９０，　Ｖｏｌ．３４，　ｐ．２６０-２７０ *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020182497A (ja) * 2014-10-15 2020-11-12 バーク アンド ボイヤー エヌワイシーＢｕｒｋｅ ＆ Ｂｏｙｅｒ Ｎｙｃ 一価不飽和脂肪酸組成物およびアテローム性動脈硬化症を処置するための使用

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US20120225941A1 (en) 2012-09-06
MX2013010076A (es) 2014-04-07
EP2680837A2 (en) 2014-01-08
US20200101035A1 (en) 2020-04-02
CN103889219A (zh) 2014-06-25
CA2829051A1 (en) 2012-09-07
US20210145780A1 (en) 2021-05-20
WO2012119078A2 (en) 2012-09-07
US11337948B2 (en) 2022-05-24
US9877943B2 (en) 2018-01-30
JP2016034284A (ja) 2016-03-17
AU2019264531A1 (en) 2019-12-05
US20150224073A1 (en) 2015-08-13
US20210145781A1 (en) 2021-05-20
JP6267681B2 (ja) 2018-01-24
US20140364416A1 (en) 2014-12-11
US11419840B2 (en) 2022-08-23
US8703818B2 (en) 2014-04-22
EP3510998A1 (en) 2019-07-17
CA2829051C (en) 2020-04-28
SG193258A1 (en) 2013-10-30
US10835508B2 (en) 2020-11-17
AU2021209281A1 (en) 2021-08-19
AU2017206159A1 (en) 2017-08-03
AU2021209281B2 (en) 2023-07-27
EP2680837A4 (en) 2015-06-03
US9861602B2 (en) 2018-01-09
AU2015238924A1 (en) 2015-10-29
AU2012223171A1 (en) 2013-05-02
AU2019264531B2 (en) 2021-05-13
AU2012223171B2 (en) 2015-07-16
KR20140010126A (ko) 2014-01-23
AU2015238924B2 (en) 2017-04-27
WO2012119078A3 (en) 2014-04-24

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