AU2012223171B2 - Compositions and methods comprising C16:1n7-palmitoleate - Google Patents

Compositions and methods comprising C16:1n7-palmitoleate Download PDF

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Publication number
AU2012223171B2
AU2012223171B2 AU2012223171A AU2012223171A AU2012223171B2 AU 2012223171 B2 AU2012223171 B2 AU 2012223171B2 AU 2012223171 A AU2012223171 A AU 2012223171A AU 2012223171 A AU2012223171 A AU 2012223171A AU 2012223171 B2 AU2012223171 B2 AU 2012223171B2
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Prior art keywords
palmitoleate
baseline
derivative
derivatives
subject
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AU2012223171A1 (en
Inventor
Jeffrey Green
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Tersus Life Sciences LLC
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Tersus Pharmaceuticals LLC
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Priority to AU2015238924A priority Critical patent/AU2015238924B2/en
Priority to AU2017206159A priority patent/AU2017206159A1/en
Priority to AU2019264531A priority patent/AU2019264531B2/en
Priority to AU2021209281A priority patent/AU2021209281B2/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
AU2012223171A 2011-03-03 2012-03-02 Compositions and methods comprising C16:1n7-palmitoleate Active AU2012223171B2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2015238924A AU2015238924B2 (en) 2011-03-03 2015-10-12 Compositions and methods comprising C16:1n7-palmitoleate
AU2017206159A AU2017206159A1 (en) 2011-03-03 2017-07-18 Compositions and methods comprising C16:1n7-palmitoleate
AU2019264531A AU2019264531B2 (en) 2011-03-03 2019-11-11 Compositions and methods comprising C16:1n7-palmitoleate
AU2021209281A AU2021209281B2 (en) 2011-03-03 2021-07-29 COMPOSITIONS AND METHODS COMPRISING C16:1n7-PALMITOLEATE

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161449015P 2011-03-03 2011-03-03
US61/449,015 2011-03-03
PCT/US2012/027489 WO2012119078A2 (en) 2011-03-03 2012-03-02 COMPOSITIONS AND METHODS COMPRISING C16:1n7-PALMITOLEATE

Related Child Applications (1)

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AU2015238924A Division AU2015238924B2 (en) 2011-03-03 2015-10-12 Compositions and methods comprising C16:1n7-palmitoleate

Publications (2)

Publication Number Publication Date
AU2012223171A1 AU2012223171A1 (en) 2013-05-02
AU2012223171B2 true AU2012223171B2 (en) 2015-07-16

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Family Applications (5)

Application Number Title Priority Date Filing Date
AU2012223171A Active AU2012223171B2 (en) 2011-03-03 2012-03-02 Compositions and methods comprising C16:1n7-palmitoleate
AU2015238924A Active AU2015238924B2 (en) 2011-03-03 2015-10-12 Compositions and methods comprising C16:1n7-palmitoleate
AU2017206159A Abandoned AU2017206159A1 (en) 2011-03-03 2017-07-18 Compositions and methods comprising C16:1n7-palmitoleate
AU2019264531A Active AU2019264531B2 (en) 2011-03-03 2019-11-11 Compositions and methods comprising C16:1n7-palmitoleate
AU2021209281A Active AU2021209281B2 (en) 2011-03-03 2021-07-29 COMPOSITIONS AND METHODS COMPRISING C16:1n7-PALMITOLEATE

Family Applications After (4)

Application Number Title Priority Date Filing Date
AU2015238924A Active AU2015238924B2 (en) 2011-03-03 2015-10-12 Compositions and methods comprising C16:1n7-palmitoleate
AU2017206159A Abandoned AU2017206159A1 (en) 2011-03-03 2017-07-18 Compositions and methods comprising C16:1n7-palmitoleate
AU2019264531A Active AU2019264531B2 (en) 2011-03-03 2019-11-11 Compositions and methods comprising C16:1n7-palmitoleate
AU2021209281A Active AU2021209281B2 (en) 2011-03-03 2021-07-29 COMPOSITIONS AND METHODS COMPRISING C16:1n7-PALMITOLEATE

Country Status (10)

Country Link
US (6) US8703818B2 (enExample)
EP (2) EP3510998A1 (enExample)
JP (2) JP2014518609A (enExample)
KR (1) KR20140010126A (enExample)
CN (1) CN103889219A (enExample)
AU (5) AU2012223171B2 (enExample)
CA (1) CA2829051C (enExample)
MX (1) MX2013010076A (enExample)
SG (1) SG193258A1 (enExample)
WO (1) WO2012119078A2 (enExample)

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US9200236B2 (en) 2011-11-17 2015-12-01 Heliae Development, Llc Omega 7 rich compositions and methods of isolating omega 7 fatty acids
US10123986B2 (en) 2012-12-24 2018-11-13 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US9629820B2 (en) 2012-12-24 2017-04-25 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US9266973B2 (en) 2013-03-15 2016-02-23 Aurora Algae, Inc. Systems and methods for utilizing and recovering chitosan to process biological material
US20140275613A1 (en) * 2013-03-15 2014-09-18 Aurora Algae, Inc. Conversion of free fatty acids to ethyl esters
WO2015077499A1 (en) 2013-11-22 2015-05-28 Heliae Development, Llc Isolation of omega-7 fatty acid ethyl esters from natural oils
KR102243022B1 (ko) * 2014-03-05 2021-04-21 삼성메디슨 주식회사 선택 정보에 기초하여 관심 영역에 포함된 혈류에 대한 정보를 출력하는 방법, 장치 및 시스템.
WO2015187997A1 (en) 2014-06-04 2015-12-10 Tersus Pharmaceuticals, LLC METHODS OF TREATING CHRONIC DRY EYE DISEASE USING C16:1n7 PALMITOLEATE AND DERIVATIVES THEREOF
EP3166415A4 (en) * 2014-07-08 2017-12-06 Omega Protein Corporation Enrichment of palmitoleic acid palmitoleic acid derivatives by dry and solvent-aided winterization
WO2016011410A1 (en) * 2014-07-17 2016-01-21 Cornell University Omega-3 fatty acid enrichment of poultry products with defatted microalgae animal feed
CA2963980A1 (en) * 2014-10-15 2016-04-21 Burke & Boyer Nyc Monounsaturated fatty acid compositions and use for treating atherosclerosis
US10058524B2 (en) 2015-02-18 2018-08-28 Tersus Life Sciences, LLC Methods for improving joint function
IT201600093741A1 (it) * 2016-09-19 2018-03-19 Codex V Srl Insaponificabili di lipidi naturali per l’uso nel trattamento di patologie cardiache
TWI750189B (zh) 2016-12-15 2021-12-21 大陸商深圳瑞健生命科學研究院有限公司 一種治療冠狀動脈粥樣硬化及其併發症的方法
CN108210904A (zh) * 2016-12-15 2018-06-29 深圳瑞健生命科学研究院有限公司 治疗动脉粥样硬化及其并发症的药物及其用途
JP7168990B2 (ja) 2016-12-15 2022-11-10 タレンゲン インターナショナル リミテッド 肥満症を予防および治療するための方法および薬物
AU2022248850A1 (en) 2021-03-27 2023-11-09 TRx Biosciences Limited Compositions having improved bioavailability of therapeutics
JP2026011459A (ja) * 2024-07-11 2026-01-23 日油株式会社 パルミトレイン酸を含有する脂肪酸組成物

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WO2010028336A2 (en) * 2008-09-08 2010-03-11 President And Fellows Of Harvard College Fatty acid c16:1n7-palmitoleate a lipokine and biomarker for metabolic status
WO2010118362A1 (en) * 2009-04-09 2010-10-14 The Regents Of The University Of Colorado, A Body Corporate Methods and compositions for inducing physiological hypertrophy

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US20120225941A1 (en) 2012-09-06
MX2013010076A (es) 2014-04-07
EP2680837A2 (en) 2014-01-08
US20200101035A1 (en) 2020-04-02
CN103889219A (zh) 2014-06-25
CA2829051A1 (en) 2012-09-07
US20210145780A1 (en) 2021-05-20
WO2012119078A2 (en) 2012-09-07
US11337948B2 (en) 2022-05-24
US9877943B2 (en) 2018-01-30
JP2016034284A (ja) 2016-03-17
AU2019264531A1 (en) 2019-12-05
US20150224073A1 (en) 2015-08-13
US20210145781A1 (en) 2021-05-20
JP6267681B2 (ja) 2018-01-24
US20140364416A1 (en) 2014-12-11
US11419840B2 (en) 2022-08-23
US8703818B2 (en) 2014-04-22
EP3510998A1 (en) 2019-07-17
CA2829051C (en) 2020-04-28
SG193258A1 (en) 2013-10-30
US10835508B2 (en) 2020-11-17
AU2021209281A1 (en) 2021-08-19
AU2017206159A1 (en) 2017-08-03
JP2014518609A (ja) 2014-08-07
AU2021209281B2 (en) 2023-07-27
EP2680837A4 (en) 2015-06-03
US9861602B2 (en) 2018-01-09
AU2015238924A1 (en) 2015-10-29
AU2012223171A1 (en) 2013-05-02
AU2019264531B2 (en) 2021-05-13
KR20140010126A (ko) 2014-01-23
AU2015238924B2 (en) 2017-04-27
WO2012119078A3 (en) 2014-04-24

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