JP2014517028A5 - - Google Patents
Info
- Publication number
- JP2014517028A5 JP2014517028A5 JP2014515299A JP2014515299A JP2014517028A5 JP 2014517028 A5 JP2014517028 A5 JP 2014517028A5 JP 2014515299 A JP2014515299 A JP 2014515299A JP 2014515299 A JP2014515299 A JP 2014515299A JP 2014517028 A5 JP2014517028 A5 JP 2014517028A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- oil
- emulsion
- drug
- triglycerides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 34
- 229940106134 krill oil Drugs 0.000 claims 15
- 229940079593 drug Drugs 0.000 claims 11
- 239000003814 drug Substances 0.000 claims 11
- 239000000839 emulsion Substances 0.000 claims 10
- 150000003626 triacylglycerols Chemical class 0.000 claims 10
- 235000021323 fish oil Nutrition 0.000 claims 9
- 150000003904 phospholipids Chemical class 0.000 claims 9
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 4
- 239000007764 o/w emulsion Substances 0.000 claims 4
- 239000003921 oil Substances 0.000 claims 4
- 235000019198 oils Nutrition 0.000 claims 4
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 4
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 4
- 239000008346 aqueous phase Substances 0.000 claims 3
- 239000012071 phase Substances 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 3
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 3
- 239000008158 vegetable oil Substances 0.000 claims 3
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- -1 medium chain fatty acid triglycerides Chemical class 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 2
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 206010040047 Sepsis Diseases 0.000 claims 1
- 229940087168 alpha tocopherol Drugs 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008344 egg yolk phospholipid Substances 0.000 claims 1
- 239000002158 endotoxin Substances 0.000 claims 1
- 230000003832 immune regulation Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000036542 oxidative stress Effects 0.000 claims 1
- 231100000572 poisoning Toxicity 0.000 claims 1
- 230000000607 poisoning effect Effects 0.000 claims 1
- 229960000984 tocofersolan Drugs 0.000 claims 1
- 231100000331 toxic Toxicity 0.000 claims 1
- 230000002588 toxic effect Effects 0.000 claims 1
- 239000002076 α-tocopherol Substances 0.000 claims 1
- 235000004835 α-tocopherol Nutrition 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/161,101 US8895074B2 (en) | 2011-06-15 | 2011-06-15 | Therapeutic application of parenteral krill oil |
| US13/161,101 | 2011-06-15 | ||
| EP11179821 | 2011-09-02 | ||
| EP11179821.1 | 2011-09-02 | ||
| PCT/IB2012/001156 WO2012172411A1 (en) | 2011-06-15 | 2012-06-13 | Therapeutic application of parenteral krill oil |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014517028A JP2014517028A (ja) | 2014-07-17 |
| JP2014517028A5 true JP2014517028A5 (enExample) | 2015-07-30 |
| JP5864735B2 JP5864735B2 (ja) | 2016-02-17 |
Family
ID=46456944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014515299A Expired - Fee Related JP5864735B2 (ja) | 2011-06-15 | 2012-06-13 | 非経口オキアミ油の治療用途 |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP2720701B1 (enExample) |
| JP (1) | JP5864735B2 (enExample) |
| KR (1) | KR101841588B1 (enExample) |
| CN (2) | CN107648268B (enExample) |
| BR (1) | BR112013032224B1 (enExample) |
| CA (1) | CA2838312C (enExample) |
| CY (1) | CY1119417T1 (enExample) |
| DK (1) | DK2720701T3 (enExample) |
| ES (1) | ES2643843T3 (enExample) |
| HR (1) | HRP20171431T1 (enExample) |
| HU (1) | HUE036720T2 (enExample) |
| IL (1) | IL229690A (enExample) |
| LT (1) | LT2720701T (enExample) |
| MX (1) | MX351895B (enExample) |
| PL (1) | PL2720701T3 (enExample) |
| PT (1) | PT2720701T (enExample) |
| RS (1) | RS56394B1 (enExample) |
| RU (1) | RU2625760C2 (enExample) |
| SI (1) | SI2720701T1 (enExample) |
| SM (1) | SMT201700470T1 (enExample) |
| TW (1) | TWI592160B (enExample) |
| WO (1) | WO2012172411A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014183047A1 (en) * | 2013-05-10 | 2014-11-13 | Memorial Sloan Kettering Cancer Center | Lipid scavenging in ras cancers |
| GB201402457D0 (en) | 2014-02-12 | 2014-03-26 | Aker Biomarine As | Capsules containing high doses of phospholipids |
| GB201402450D0 (en) | 2014-02-12 | 2014-03-26 | Aker Biomarine As | Liquid phospholipid-containing compositions for preperation of pharmaceuticals |
| GB201407345D0 (en) | 2014-04-25 | 2014-06-11 | Aker Biomarine As | Krill Phospholipid compositions |
| US10898525B2 (en) | 2014-04-30 | 2021-01-26 | Aker Biomarine Antarctic As | Krill oil preparations and their uses |
| US11147841B2 (en) | 2014-12-19 | 2021-10-19 | Aker Biomarine Antarctic As | Enhanced omega-3 formulations |
| HK1250632A1 (zh) * | 2015-03-31 | 2019-01-11 | 费森尤斯卡比德国有限公司 | 用於肠胃外给药的乳液 |
| CN105901740A (zh) * | 2016-04-26 | 2016-08-31 | 济南极源生物科技有限公司 | 一种南极磷虾油可食用营养品 |
| JP7370317B2 (ja) * | 2017-08-10 | 2023-10-27 | ザ チルドレンズ メディカル センター コーポレーション | 魚油および／またはオメガ３脂肪酸を含むエマルジョンに関する方法および組成物 |
| EP3536332A1 (en) * | 2018-03-07 | 2019-09-11 | Athenion AG | Krill oil for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents |
| KR102451162B1 (ko) * | 2020-09-07 | 2022-10-06 | (주)에스디생명공학 | 효소처리 크릴 오일 추출물을 유효성분으로 포함하는 항염증, 피부 주름개선, 보습 및 피부 재생 촉진용 조성물 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9101642D0 (sv) * | 1991-05-30 | 1991-05-30 | Kabi Pharmacia Ab | Phospholipids |
| JPH08231391A (ja) * | 1995-02-24 | 1996-09-10 | Kanagawa Kagaku Kenkyusho:Kk | 痴呆症状改善薬 |
| JP4761093B2 (ja) * | 1997-12-10 | 2011-08-31 | シクロスポリン セラポイティクス リミテッド | オメガ−３脂肪酸油を含む医薬組成物 |
| GB0012597D0 (en) * | 2000-05-25 | 2000-07-12 | Astrazeneca Ab | Formulation |
| ES2386841T3 (es) * | 2001-06-18 | 2012-09-03 | Neptune Technologies & Bioressources Inc. | Extractos de krill para la prevención y/o el tratamiento de enfermedades cardiovasculares |
| US7666447B2 (en) * | 2004-10-08 | 2010-02-23 | Pharmanutrients | Compositions including Krill extracts and conjugated linoleic acid and methods of using same |
| CN101321477A (zh) * | 2005-10-07 | 2008-12-10 | 加拿大海洋营养食品有限公司 | 脂肪酸盐及其制备和使用方法 |
| ZA200904176B (en) * | 2006-11-16 | 2010-08-25 | Pronova Biopharma Norge As | Process for production of Omega-3 rich marine phospho-lipids from krill |
| EP2144618B2 (en) | 2007-03-28 | 2024-11-20 | Aker Biomarine Antarctic As | Bioeffective krill oil compositions |
| WO2008140026A1 (ja) * | 2007-05-11 | 2008-11-20 | Bizen Chemical Co., Ltd. | 新規のロイコトリエン受容体アンタゴニスト |
| NO327925B1 (no) * | 2007-06-25 | 2009-10-19 | Pharmalogica As | Anvendelse av kullsyre i drikker omfattende polyumettede fettsyrer (PUFA) for a hindre oksidasjon av fettsyrene. |
| US20090099261A1 (en) * | 2007-09-25 | 2009-04-16 | Isi Brands Inc. | Omega-3 mixtures |
| US20100062057A1 (en) * | 2008-09-10 | 2010-03-11 | Pronova BioPharma Norge AS. | Formulation |
| US20100130619A1 (en) * | 2008-11-24 | 2010-05-27 | Joseph Schwarz | Pharmaceutical composition for parenteral administration of idebenone |
| US8241672B2 (en) | 2009-03-11 | 2012-08-14 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| US20110071090A1 (en) * | 2009-03-11 | 2011-03-24 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle |
| NO333013B1 (no) * | 2009-07-06 | 2013-02-18 | Smartfish As | Sammensetning omfattende bioaktive aminosyrer eller derivater derav og marin olje i en stabil olje-i-vannemulsjon, og fremgangsmate for fremstilling av nevnte sammensetning. |
| AU2009354456B2 (en) * | 2009-10-30 | 2014-05-08 | Tharos Ltd | Solvent-free process for obtaining phospholipids and neutral enriched krill oils |
-
2012
- 2012-06-13 RS RS20170981A patent/RS56394B1/sr unknown
- 2012-06-13 SM SM20170470T patent/SMT201700470T1/it unknown
- 2012-06-13 DK DK12731667.7T patent/DK2720701T3/en active
- 2012-06-13 EP EP12731667.7A patent/EP2720701B1/en active Active
- 2012-06-13 ES ES12731667.7T patent/ES2643843T3/es active Active
- 2012-06-13 HR HRP20171431TT patent/HRP20171431T1/hr unknown
- 2012-06-13 PL PL12731667T patent/PL2720701T3/pl unknown
- 2012-06-13 CA CA2838312A patent/CA2838312C/en not_active Expired - Fee Related
- 2012-06-13 MX MX2013014901A patent/MX351895B/es active IP Right Grant
- 2012-06-13 JP JP2014515299A patent/JP5864735B2/ja not_active Expired - Fee Related
- 2012-06-13 CN CN201710990052.1A patent/CN107648268B/zh not_active Expired - Fee Related
- 2012-06-13 HU HUE12731667A patent/HUE036720T2/hu unknown
- 2012-06-13 LT LTEP12731667.7T patent/LT2720701T/lt unknown
- 2012-06-13 CN CN201280028987.7A patent/CN103608023A/zh active Pending
- 2012-06-13 RU RU2014101067A patent/RU2625760C2/ru active
- 2012-06-13 SI SI201231091T patent/SI2720701T1/sl unknown
- 2012-06-13 WO PCT/IB2012/001156 patent/WO2012172411A1/en not_active Ceased
- 2012-06-13 KR KR1020147001111A patent/KR101841588B1/ko not_active Expired - Fee Related
- 2012-06-13 BR BR112013032224-1A patent/BR112013032224B1/pt not_active IP Right Cessation
- 2012-06-13 PT PT127316677T patent/PT2720701T/pt unknown
- 2012-06-15 TW TW101121508A patent/TWI592160B/zh not_active IP Right Cessation
-
2013
- 2013-11-28 IL IL229690A patent/IL229690A/en active IP Right Grant
-
2017
- 2017-10-04 CY CY20171101030T patent/CY1119417T1/el unknown
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