JP2014513036A5 - - Google Patents
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- Publication number
- JP2014513036A5 JP2014513036A5 JP2013536737A JP2013536737A JP2014513036A5 JP 2014513036 A5 JP2014513036 A5 JP 2014513036A5 JP 2013536737 A JP2013536737 A JP 2013536737A JP 2013536737 A JP2013536737 A JP 2013536737A JP 2014513036 A5 JP2014513036 A5 JP 2014513036A5
- Authority
- JP
- Japan
- Prior art keywords
- dmf
- diisopropylphosphorano
- rucl
- dimethylformamide
- benzene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013536737A JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011032610 | 2011-02-17 | ||
| JP2011032610 | 2011-02-17 | ||
| PCT/JP2012/054337 WO2012111849A1 (en) | 2011-02-17 | 2012-02-16 | Production method of optically active dihydrobenzofuran derivative |
| JP2013536737A JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014513036A JP2014513036A (ja) | 2014-05-29 |
| JP2014513036A5 true JP2014513036A5 (https=) | 2015-04-02 |
| JP5945545B2 JP5945545B2 (ja) | 2016-07-05 |
Family
ID=45841559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013536737A Expired - Fee Related JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8952185B2 (https=) |
| EP (1) | EP2675774A1 (https=) |
| JP (1) | JP5945545B2 (https=) |
| KR (1) | KR20140015371A (https=) |
| CN (1) | CN103492348A (https=) |
| AR (1) | AR085252A1 (https=) |
| AU (1) | AU2012218401A1 (https=) |
| BR (1) | BR112013020634A2 (https=) |
| CA (1) | CA2827271A1 (https=) |
| CL (1) | CL2013002356A1 (https=) |
| CO (1) | CO6761376A2 (https=) |
| CR (1) | CR20130407A (https=) |
| DO (1) | DOP2013000188A (https=) |
| EA (1) | EA201391180A1 (https=) |
| EC (1) | ECSP13012855A (https=) |
| IL (1) | IL227879A0 (https=) |
| MA (1) | MA34965B1 (https=) |
| MX (1) | MX2013009526A (https=) |
| PH (1) | PH12013501718A1 (https=) |
| SG (1) | SG192645A1 (https=) |
| TN (1) | TN2013000347A1 (https=) |
| TW (1) | TW201245169A (https=) |
| UY (1) | UY33913A (https=) |
| WO (1) | WO2012111849A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103145663B (zh) * | 2013-03-01 | 2016-03-23 | 上海高准医药有限公司 | (s)-2-(2,3-二氢苯并呋喃-3-基)乙酸衍生物，其制备方法及其在医药上的应用 |
| CN104250239B (zh) * | 2013-06-29 | 2016-09-07 | 山东轩竹医药科技有限公司 | 芳香多环羧酸衍生物 |
| CN104370864B (zh) * | 2013-08-14 | 2016-04-13 | 成都苑东生物制药股份有限公司 | 一种2-(6-羟基-2,3-二氢苯并呋喃-3-基)乙腈化合物和以该化合物制备tak-875药物的方法 |
| EP3049396B1 (en) * | 2013-09-26 | 2017-11-15 | Boehringer Ingelheim International GmbH | Process and intermediates for preparing indanyloxydihydrobenzofuranyl acetic acid derivatives as gpr40 agonists |
| EP3068788A1 (en) | 2013-11-14 | 2016-09-21 | Cadila Healthcare Limited | Novel heterocyclic compounds |
| EP3076959B1 (en) | 2013-12-04 | 2018-07-04 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| CN104177320B (zh) * | 2014-08-27 | 2016-03-02 | 广东东阳光药业有限公司 | 一种脲取代联苯类化合物及其组合物及用途 |
| BR112017019918B1 (pt) * | 2015-03-19 | 2023-11-07 | Daiichi Sankyo Company, Limited | Preparação sólida farmacêutica, e, método para produzir uma preparação sólida farmacêutica para estabilizar uma preparação sólida farmacêutica |
| BR112017019920B1 (pt) | 2015-03-19 | 2023-11-07 | Daiichi Sankyo Company, Limited | Preparação sólida farmacêutica, e, método para estabilização de uma preparação sólida farmacêutica |
| CN105418563B (zh) * | 2015-12-28 | 2017-11-10 | 山东大学 | Tak‑875类似物及其制备方法与应用 |
| CN107543872B (zh) * | 2016-06-29 | 2022-03-08 | 南京长澳医药科技有限公司 | 通过手性高效液相色谱法分离测定甲苯磺酸依度沙班水合物与其异构体杂质的方法 |
| WO2018077699A1 (en) | 2016-10-25 | 2018-05-03 | Boehringer Ingelheim International Gmbh | Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| US10919859B2 (en) | 2017-01-26 | 2021-02-16 | Boehringer Ingelheim International Gmbh | Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| CN106977478B (zh) * | 2017-04-21 | 2019-04-09 | 山东大学 | 一种2-(6-羟基-2,3-二氢苯并呋喃-3-基)乙酸甲酯的手性拆分方法 |
| CR20200347A (es) | 2018-02-13 | 2020-09-23 | Gilead Sciences Inc | Inhibidores pd-1/pd-l1 |
| TWI712412B (zh) | 2018-04-19 | 2020-12-11 | 美商基利科學股份有限公司 | Pd‐1/pd‐l1抑制劑 |
| SG11202012425QA (en) | 2018-07-13 | 2021-01-28 | Gilead Sciences Inc | Pd-1/pd-l1 inhibitors |
| BR112021001008A2 (pt) | 2018-07-30 | 2021-04-20 | Daiichi Sankyo Company, Limited | comprimido de fármaco |
| WO2020086556A1 (en) | 2018-10-24 | 2020-04-30 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| KR20220150270A (ko) | 2019-10-07 | 2022-11-10 | 칼리오페, 인크. | Gpr119 효능제 |
| TW202140440A (zh) | 2020-02-28 | 2021-11-01 | 美商克力歐普股份有限公司 | Gpr40激動劑 |
| WO2021236617A1 (en) | 2020-05-19 | 2021-11-25 | Kallyope, Inc. | Ampk activators |
| CN116390925A (zh) | 2020-06-26 | 2023-07-04 | 卡尔优普公司 | Ampk活化剂 |
| CN114539168B (zh) * | 2020-11-27 | 2023-11-17 | 武汉大学 | 一种合成Piragliatin及其类似物的方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1072649C (zh) | 1995-09-13 | 2001-10-10 | 武田药品工业株式会社 | 苯并氧杂吖庚因化合物,其生产方法和用途 |
| AR035016A1 (es) | 1999-08-25 | 2004-04-14 | Takeda Chemical Industries Ltd | Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima. |
| CA2416384A1 (en) | 2000-07-17 | 2003-01-16 | Takeda Chemical Industries, Ltd. | Sulfone derivatives, their production and use |
| AU2003278600A1 (en) | 2002-11-01 | 2004-05-25 | Takeda Pharmaceutical Company Limited | Agent for preventing or treating neuropathy |
| CA2505322A1 (en) | 2002-11-08 | 2004-05-21 | Takeda Pharmaceutical Company Limited | Receptor function regulator |
| US20070004736A1 (en) | 2002-11-22 | 2007-01-04 | Keiji Kubo | Imidazole derivative, process for producing the same, and use |
| EP1630152A4 (en) | 2003-05-30 | 2009-09-23 | Takeda Pharmaceutical | CONDENSED CYCLIC COMPOUND |
| EP1669352A4 (en) | 2003-09-30 | 2008-12-17 | Takeda Pharmaceutical | THIAZOLINE DERIVATIVE AND ITS USE |
| EP1695961A4 (en) | 2003-12-17 | 2007-10-24 | Takeda Pharmaceutical | UREA DERIVATIVE, METHOD FOR THE PRODUCTION AND THEIR USE |
| AU2004309271A1 (en) | 2003-12-25 | 2005-07-14 | Takeda Pharmaceutical Company Limited | 3-(4-benzyloxyphenyl)propanoic acid derivatives |
| WO2005063725A1 (ja) | 2003-12-26 | 2005-07-14 | Takeda Pharmaceutical Company Limited | フェニルプロパン酸誘導体 |
| JP4875978B2 (ja) | 2004-03-15 | 2012-02-15 | 武田薬品工業株式会社 | アミノフェニルプロパン酸誘導体 |
| US7517910B2 (en) | 2004-03-30 | 2009-04-14 | Takeda Pharmaceutical Company Limited | Alkoxyphenylpropanoic acid derivatives |
| TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| GB0428101D0 (en) * | 2004-12-23 | 2005-01-26 | Astrazeneca Ab | Chemical Processes & Intermediates |
| US8957070B2 (en) | 2005-04-20 | 2015-02-17 | Takeda Pharmaceutical Company Limited | Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity |
| US20090054435A1 (en) | 2005-07-29 | 2009-02-26 | Hiroshi Imoto | Phenoxyalkanoic Acid Compound |
| EP1916234B1 (en) | 2005-07-29 | 2014-11-12 | Takeda Pharmaceutical Company Limited | Cyclopropanecarboxylic acid compound |
| TW200740435A (en) | 2005-08-10 | 2007-11-01 | Takeda Pharmaceuticals Co | Therapeutic agent for diabetes |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| RS53230B (sr) | 2006-06-27 | 2014-08-29 | Takeda Pharmaceutical Company Limited | Kondenzovana ciklična jedinjenja kao modulatori gpr40 receptora |
| US8492405B2 (en) | 2006-10-18 | 2013-07-23 | Takeda Pharmaceutical Company Limited | Glucokinase-activating fused heterocyclic compounds and methods of treating diabetes and obesity |
| RU2454415C9 (ru) | 2006-10-19 | 2013-02-27 | Такеда Фармасьютикал Компани Лимитед | Производное индола |
| EP2128138A1 (en) | 2007-01-29 | 2009-12-02 | Takeda Pharmaceutical Company Limited | Pyrazole compound |
| JP2010517935A (ja) | 2007-02-09 | 2010-05-27 | 武田薬品工業株式会社 | Ｐｐａｒ−ガンマのパーシャルアゴニストとしての縮合環化合物 |
| WO2008101197A1 (en) | 2007-02-18 | 2008-08-21 | University Of Florida Research Foundation, Inc. | Catalysts containing n-heterocyclic carbenes for enantioselective synthesis |
| JPWO2008136428A1 (ja) | 2007-04-27 | 2010-07-29 | 武田薬品工業株式会社 | 含窒素５員複素環化合物 |
| WO2008156757A1 (en) | 2007-06-19 | 2008-12-24 | Takeda Pharmaceutical Company Limited | Indazole compounds for activating glucokinase |
| WO2010143733A1 (en) | 2009-06-09 | 2010-12-16 | Takeda Pharmaceutical Company Limited | Novel fused cyclic compound and use thereof |
| JP5129209B2 (ja) | 2009-08-03 | 2013-01-30 | ゴールドフラッグ株式会社 | ブラジャー及び該ブラジャー付き下着とこれをインナーとしたアウター |
-
2012
- 2012-02-16 JP JP2013536737A patent/JP5945545B2/ja not_active Expired - Fee Related
- 2012-02-16 EP EP12709184.1A patent/EP2675774A1/en not_active Withdrawn
- 2012-02-16 AU AU2012218401A patent/AU2012218401A1/en not_active Abandoned
- 2012-02-16 SG SG2013059803A patent/SG192645A1/en unknown
- 2012-02-16 CN CN201280018878.7A patent/CN103492348A/zh active Pending
- 2012-02-16 WO PCT/JP2012/054337 patent/WO2012111849A1/en not_active Ceased
- 2012-02-16 MX MX2013009526A patent/MX2013009526A/es not_active Application Discontinuation
- 2012-02-16 PH PH1/2013/501718A patent/PH12013501718A1/en unknown
- 2012-02-16 BR BR112013020634A patent/BR112013020634A2/pt not_active IP Right Cessation
- 2012-02-16 US US13/985,395 patent/US8952185B2/en not_active Expired - Fee Related
- 2012-02-16 AR ARP120100517A patent/AR085252A1/es not_active Application Discontinuation
- 2012-02-16 TW TW101105030A patent/TW201245169A/zh unknown
- 2012-02-16 CA CA2827271A patent/CA2827271A1/en not_active Abandoned
- 2012-02-16 UY UY0001033913A patent/UY33913A/es not_active Application Discontinuation
- 2012-02-16 KR KR1020137024534A patent/KR20140015371A/ko not_active Withdrawn
- 2012-02-16 EA EA201391180A patent/EA201391180A1/ru unknown
- 2012-02-16 MA MA36243A patent/MA34965B1/fr unknown
-
2013
- 2013-08-08 IL IL227879A patent/IL227879A0/en unknown
- 2013-08-14 CL CL2013002356A patent/CL2013002356A1/es unknown
- 2013-08-15 DO DO2013000188A patent/DOP2013000188A/es unknown
- 2013-08-16 TN TNP2013000347A patent/TN2013000347A1/fr unknown
- 2013-08-23 CR CR20130407A patent/CR20130407A/es not_active Application Discontinuation
- 2013-08-28 EC ECSP13012855 patent/ECSP13012855A/es unknown
- 2013-09-17 CO CO13220813A patent/CO6761376A2/es unknown
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