JP2014510152A - 粘度が低減された処方物 - Google Patents
粘度が低減された処方物 Download PDFInfo
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- JP2014510152A JP2014510152A JP2014504014A JP2014504014A JP2014510152A JP 2014510152 A JP2014510152 A JP 2014510152A JP 2014504014 A JP2014504014 A JP 2014504014A JP 2014504014 A JP2014504014 A JP 2014504014A JP 2014510152 A JP2014510152 A JP 2014510152A
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| PCT/US2012/032464 WO2012141978A2 (en) | 2011-04-07 | 2012-04-06 | Formulations with reduced viscosity |
Publications (2)
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| JP2014510152A true JP2014510152A (ja) | 2014-04-24 |
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| EP (1) | EP2694708A4 (enExample) |
| JP (1) | JP2014510152A (enExample) |
| KR (1) | KR20140066124A (enExample) |
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| IL (1) | IL228626A0 (enExample) |
| SG (1) | SG193964A1 (enExample) |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014516924A (ja) * | 2011-04-07 | 2014-07-17 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 粘度が低減された処方物 |
| JP2018188430A (ja) * | 2017-04-28 | 2018-11-29 | アムジエン・インコーポレーテツド | ヒト抗ｒａｎｋｌ抗体の製剤及びその使用方法 |
| JP2021517129A (ja) * | 2018-03-07 | 2021-07-15 | ファイザー・インク | 抗ｐｄ−１抗体組成物 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2523688T3 (en) * | 2010-01-15 | 2017-12-04 | Kirin-Amgen Inc | ANTIBODY FORMULATION AND THERAPEUTIC REGIMENS |
| KR20150032941A (ko) * | 2012-06-21 | 2015-03-31 | 유씨비 파마, 에스.에이. | 약학 제제 |
| FR2994390B1 (fr) | 2012-08-10 | 2014-08-15 | Adocia | Procede d'abaissement de la viscosite de solutions de proteines a concentration elevee |
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| IL312865B2 (en) | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-lowering agents |
| SG10201902915VA (en) | 2014-10-01 | 2019-04-29 | Eagle Biologics Inc | Polysaccharide and nucleic acid formulations containing viscosity-lowering agents |
| TWI780988B (zh) | 2015-08-24 | 2022-10-11 | 英商葛蘭素史密斯克藍智慧財產權有限公司 | 生藥組成物 |
| CN105733250B (zh) * | 2016-05-04 | 2017-12-26 | 山东省药学科学院 | 一种交联聚谷氨酸悬浮液及其制备方法与应用 |
| CA3049857A1 (en) * | 2017-01-11 | 2018-07-19 | Celltrion Inc. | Stable liquid formulation |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| AU2018263868A1 (en) | 2017-05-02 | 2019-12-12 | Merck Sharp & Dohme Llc | Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies |
| SG11202003754YA (en) | 2017-05-16 | 2020-05-28 | Bhamis Research Laboratory Pvt Ltd | High concentration protein formulations with reduced viscosity |
| JP7295038B2 (ja) | 2017-06-06 | 2023-06-20 | グラクソスミスクライン エルエルシー | 小児患者のための生物薬剤組成物及び方法 |
| CA3118144A1 (en) | 2018-11-07 | 2020-05-14 | Merck Sharp & Dohme Corp. | Co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies |
| AU2020263318B2 (en) * | 2019-04-23 | 2025-10-23 | Amgen Inc. | The use of low molecular weight polyvinylpyrrolidone (PVP) to reduce viscosity of high concentration protein formulations |
| GB202102258D0 (en) * | 2021-02-17 | 2021-03-31 | Arecor Ltd | Novel composition |
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| WO2007074880A1 (ja) * | 2005-12-28 | 2007-07-05 | Chugai Seiyaku Kabushiki Kaisha | 抗体含有安定化製剤 |
| JP2009510046A (ja) * | 2005-09-30 | 2009-03-12 | メドイミューン・リミテッド | インターロイキン−１３抗体組成物 |
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| UA107557C2 (xx) * | 2007-07-06 | 2015-01-26 | Композиція антитіла офатумумабу | |
| CA2701032C (en) * | 2007-09-27 | 2021-01-26 | Amgen Inc. | Pharmaceutical formulations |
| PE20091174A1 (es) * | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| EP2515941B1 (en) * | 2009-12-21 | 2019-11-13 | F.Hoffmann-La Roche Ag | Pharmaceutical formulation of bevacizumab |
| JP2013525484A (ja) * | 2010-05-03 | 2013-06-20 | ジェネンテック， インコーポレイテッド | タンパク質含有製剤の粘度を低減させるために有用な組成物及び方法 |
-
2012
- 2012-04-06 US US14/110,252 patent/US20140044727A1/en not_active Abandoned
- 2012-04-06 SG SG2013072434A patent/SG193964A1/en unknown
- 2012-04-06 WO PCT/US2012/032464 patent/WO2012141978A2/en not_active Ceased
- 2012-04-06 EA EA201391489A patent/EA201391489A1/ru unknown
- 2012-04-06 BR BR112013025845A patent/BR112013025845A2/pt not_active IP Right Cessation
- 2012-04-06 CA CA2832560A patent/CA2832560A1/en not_active Abandoned
- 2012-04-06 EP EP12771966.4A patent/EP2694708A4/en not_active Withdrawn
- 2012-04-06 AU AU2012243126A patent/AU2012243126A1/en not_active Abandoned
- 2012-04-06 JP JP2014504014A patent/JP2014510152A/ja active Pending
- 2012-04-06 KR KR1020137029164A patent/KR20140066124A/ko not_active Withdrawn
- 2012-04-06 CN CN201280025770.0A patent/CN103582724A/zh active Pending
-
2013
- 2013-09-29 IL IL228626A patent/IL228626A0/en unknown
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| JP2009510046A (ja) * | 2005-09-30 | 2009-03-12 | メドイミューン・リミテッド | インターロイキン−１３抗体組成物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014516924A (ja) * | 2011-04-07 | 2014-07-17 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 粘度が低減された処方物 |
| JP2018188430A (ja) * | 2017-04-28 | 2018-11-29 | アムジエン・インコーポレーテツド | ヒト抗ｒａｎｋｌ抗体の製剤及びその使用方法 |
| JP2022062059A (ja) * | 2017-04-28 | 2022-04-19 | アムジエン・インコーポレーテツド | ヒト抗ｒａｎｋｌ抗体の製剤及びその使用方法 |
| JP7190822B2 (ja) | 2017-04-28 | 2022-12-16 | アムジエン・インコーポレーテツド | ヒト抗ｒａｎｋｌ抗体の製剤及びその使用方法 |
| JP7356525B2 (ja) | 2017-04-28 | 2023-10-04 | アムジエン・インコーポレーテツド | ヒト抗ｒａｎｋｌ抗体の製剤及びその使用方法 |
| JP2023166396A (ja) * | 2017-04-28 | 2023-11-21 | アムジエン・インコーポレーテツド | ヒト抗ｒａｎｋｌ抗体の製剤及びその使用方法 |
| JP2021517129A (ja) * | 2018-03-07 | 2021-07-15 | ファイザー・インク | 抗ｐｄ−１抗体組成物 |
| JP7312188B2 (ja) | 2018-03-07 | 2023-07-20 | ファイザー・インク | 抗ｐｄ－１抗体組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20140044727A1 (en) | 2014-02-13 |
| SG193964A1 (en) | 2013-11-29 |
| EP2694708A2 (en) | 2014-02-12 |
| WO2012141978A3 (en) | 2012-12-27 |
| IL228626A0 (en) | 2013-12-31 |
| AU2012243126A1 (en) | 2013-10-17 |
| EP2694708A4 (en) | 2014-10-01 |
| CN103582724A (zh) | 2014-02-12 |
| EA201391489A1 (ru) | 2014-02-28 |
| WO2012141978A2 (en) | 2012-10-18 |
| CA2832560A1 (en) | 2012-10-18 |
| BR112013025845A2 (pt) | 2018-09-04 |
| KR20140066124A (ko) | 2014-05-30 |
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