JP2014501492A5 - - Google Patents
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- Publication number
- JP2014501492A5 JP2014501492A5 JP2013532277A JP2013532277A JP2014501492A5 JP 2014501492 A5 JP2014501492 A5 JP 2014501492A5 JP 2013532277 A JP2013532277 A JP 2013532277A JP 2013532277 A JP2013532277 A JP 2013532277A JP 2014501492 A5 JP2014501492 A5 JP 2014501492A5
- Authority
- JP
- Japan
- Prior art keywords
- short rna
- strand
- rna
- short
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1016989.4 | 2010-10-08 | ||
| GBGB1016989.4A GB201016989D0 (en) | 2010-10-08 | 2010-10-08 | Cell induction |
| GBGB1103745.4A GB201103745D0 (en) | 2011-03-07 | 2011-03-07 | Cell induction |
| GB1103745.4 | 2011-03-07 | ||
| PCT/GB2011/051940 WO2012046084A2 (en) | 2010-10-08 | 2011-10-10 | Short rna molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014501492A JP2014501492A (ja) | 2014-01-23 |
| JP2014501492A5 true JP2014501492A5 (enExample) | 2014-11-13 |
| JP5681955B2 JP5681955B2 (ja) | 2015-03-11 |
Family
ID=44860439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532277A Expired - Fee Related JP5681955B2 (ja) | 2010-10-08 | 2011-10-10 | 短いrna分子 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US8835400B2 (enExample) |
| EP (2) | EP2625272B1 (enExample) |
| JP (1) | JP5681955B2 (enExample) |
| KR (1) | KR20130132795A (enExample) |
| CN (1) | CN103314108B (enExample) |
| AU (1) | AU2011311344B2 (enExample) |
| CA (1) | CA2817191A1 (enExample) |
| WO (2) | WO2012046084A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130132795A (ko) | 2010-10-08 | 2013-12-05 | 미나 테라퓨틱스 리미티드 | 짧은 rna 분자 |
| WO2014022455A1 (en) | 2012-07-31 | 2014-02-06 | The Board Of Regents Of The University Of Texas System | Methods and compositions for in vivo induction of pancreatic beta cell formation |
| CA3236835A1 (en) | 2013-11-22 | 2015-05-28 | Mina Therapeutics Limited | C/ebp alpha short activating rna compositions and methods of use |
| US20170044540A1 (en) * | 2014-04-22 | 2017-02-16 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| US20180305689A1 (en) * | 2015-04-22 | 2018-10-25 | Mina Therapeutics Limited | Sarna compositions and methods of use |
| CN106480028B (zh) * | 2016-10-12 | 2019-04-05 | 上海市第七人民医院 | TPO基因的saRNA分子及其应用 |
| WO2018237170A1 (en) * | 2017-06-21 | 2018-12-27 | Bertram Timothy A | BIOACTIVE IMMUNO-PRIVILEGE RENAL CELLS FOR THE TREATMENT OF RENAL DISEASE |
| KR102007457B1 (ko) | 2017-06-30 | 2019-08-05 | 동국대학교 산학협력단 | Cas9 단백질, 가이드 RNA 및 양친매성 펩타이드를 포함하는 나노복합체 및 이의 용도 |
| US11427826B2 (en) * | 2017-08-11 | 2022-08-30 | City of Hopw | RNA aptamers against transferrin receptor (TfR) |
| EP4219715A3 (en) | 2017-09-08 | 2023-09-06 | MiNA Therapeutics Limited | Stabilized cebpa sarna compositions and methods of use |
| CA3075205A1 (en) | 2017-09-08 | 2019-03-14 | Mina Therapeutics Limited | Stabilized hnf4a sarna compositions and methods of use |
| CA3094575A1 (en) * | 2018-04-10 | 2019-10-17 | Ractigen Therapeutics | Novel small activating rna |
| WO2019217571A1 (en) * | 2018-05-08 | 2019-11-14 | University Of Miami | Materials and methods for the delivery of therapeutic nucleic acids to tissues |
| US20210254069A1 (en) | 2018-06-15 | 2021-08-19 | Mina Therapeutics Limited | Combination therapies comprising c/ebp alpha sarna |
| CN111849968A (zh) | 2019-04-30 | 2020-10-30 | 中美瑞康核酸技术(南通)研究院有限公司 | 寡核苷酸分子及其在急性间歇性卟啉症治疗中的应用 |
| EP4017539A1 (en) | 2019-08-19 | 2022-06-29 | MiNA Therapeutics Limited | Oligonucleotide conjugate compositions and methods of use |
| EP4329777A1 (en) | 2021-04-28 | 2024-03-06 | MiNA Therapeutics Limited | Combination therapies comprising c/ebp alpha sarna |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US8193330B2 (en) | 1999-04-06 | 2012-06-05 | The Regents Of The University Of California | Polynucleotides comprising Neurogenin3 promoter and bHLH encoding domains |
| ATE450621T2 (de) | 2000-03-30 | 2009-12-15 | Whitehead Biomedical Inst | Mediatoren von rns-interferenz, die rns- sequenzspezifisch sind |
| GB0329449D0 (en) | 2003-12-19 | 2004-01-28 | Omnicyte Ltd | Stem cells |
| JP5362350B2 (ja) * | 2005-04-15 | 2013-12-11 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 小分子活性化rna分子及び使用方法 |
| US8357666B2 (en) | 2005-08-01 | 2013-01-22 | Nupotential, Inc. | Reprogramming a cell by inducing a pluripotent gene through RNA interference |
| EP2641970B1 (en) | 2005-11-17 | 2014-12-24 | Board of Regents, The University of Texas System | Modulation of gene expression by oligomers targeted to chromosomal DNA |
| JP5713377B2 (ja) | 2005-12-28 | 2015-05-07 | ザ スクリプス リサーチ インスティテュート | 薬物標的としての天然アンチセンスおよび非コードrna転写物 |
| WO2008109449A1 (en) * | 2007-03-02 | 2008-09-12 | Mdrna Inc. | Nucleic acid compounds for inhibiting bcl2 gene expression and uses thereof |
| WO2008109556A1 (en) * | 2007-03-02 | 2008-09-12 | Mdrna, Inc. | Nucleic acid compounds for inhibiting telomerase gene expression and uses thereof |
| PT2164993T (pt) | 2007-05-29 | 2017-01-12 | Reid Christopher B | Métodos para produção e usos de populações de células multipotentes, populações de células pluripotentes, populações de célula diferenciadas e populações de células resistentes a vih |
| WO2009046397A2 (en) | 2007-10-04 | 2009-04-09 | Board Of Regents, The University Of Texas System | Modulating gene expression with agrna and gapmers targeting antisense transcripts |
| JP2011507554A (ja) | 2007-12-28 | 2011-03-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 遺伝子発現を増加させるための方法および組成物 |
| EP2276838A4 (en) | 2008-04-07 | 2012-02-01 | Nupotential Inc | RE-PROGRAMMING A CELL BY INDUCING A PLURIPOTENTIC GENE THROUGH RNA INTERFERENCE |
| WO2009126927A2 (en) | 2008-04-11 | 2009-10-15 | Joslin Diabetes Center, Inc. | Methods of generating insulin-producing cells |
| WO2010047216A1 (ja) | 2008-10-23 | 2010-04-29 | 国立大学法人 東京大学 | microRNAの機能阻害法 |
| JP2012508585A (ja) | 2008-11-13 | 2012-04-12 | ベイラー リサーチ インスティテュート | インビボにおいて送達される膵島転写因子遺伝子による膵島の再生及び糖尿病の回復 |
| US20120207744A1 (en) * | 2009-03-19 | 2012-08-16 | Mendlein John D | Reprogramming compositions and methods of using the same |
| WO2010135329A2 (en) | 2009-05-18 | 2010-11-25 | Curna, Inc. | Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor |
| ES2693088T3 (es) | 2009-07-20 | 2018-12-07 | Janssen Biotech, Inc. | Diferenciación de células madre embriónicas humanas |
| CN102822342B (zh) * | 2010-01-06 | 2017-05-10 | 库尔纳公司 | 通过抑制胰腺发育基因的天然反义转录物而治疗胰腺发育基因相关疾病 |
| GB201010557D0 (en) | 2010-06-23 | 2010-08-11 | Mina Therapeutics Ltd | RNA molecules and uses thereof |
| US8635602B2 (en) | 2010-07-26 | 2014-01-21 | International Business Machines Corporation | Verification of information-flow downgraders |
| KR20130132795A (ko) * | 2010-10-08 | 2013-12-05 | 미나 테라퓨틱스 리미티드 | 짧은 rna 분자 |
-
2011
- 2011-10-10 KR KR1020137011858A patent/KR20130132795A/ko not_active Withdrawn
- 2011-10-10 CN CN201180054998.8A patent/CN103314108B/zh active Active
- 2011-10-10 EP EP11774090.2A patent/EP2625272B1/en active Active
- 2011-10-10 WO PCT/GB2011/051940 patent/WO2012046084A2/en not_active Ceased
- 2011-10-10 AU AU2011311344A patent/AU2011311344B2/en not_active Ceased
- 2011-10-10 JP JP2013532277A patent/JP5681955B2/ja not_active Expired - Fee Related
- 2011-10-10 CA CA2817191A patent/CA2817191A1/en not_active Abandoned
- 2011-10-10 WO PCT/GB2011/051942 patent/WO2012046085A2/en not_active Ceased
- 2011-10-10 US US13/877,991 patent/US8835400B2/en active Active
- 2011-10-10 EP EP11826144.5A patent/EP2625273B1/en active Active
- 2011-10-10 US US13/877,968 patent/US8916534B2/en active Active
-
2014
- 2014-11-19 US US14/547,317 patent/US9885046B2/en not_active Expired - Fee Related
-
2017
- 2017-12-11 US US15/837,377 patent/US10774331B2/en active Active
-
2020
- 2020-08-11 US US16/990,347 patent/US11365414B2/en active Active
-
2022
- 2022-05-17 US US17/746,387 patent/US20220282256A1/en not_active Abandoned
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