|
US11111543B2
(en)
|
2005-07-29 |
2021-09-07 |
Natera, Inc. |
System and method for cleaning noisy genetic data and determining chromosome copy number
|
|
US11111544B2
(en)
|
2005-07-29 |
2021-09-07 |
Natera, Inc. |
System and method for cleaning noisy genetic data and determining chromosome copy number
|
|
US9424392B2
(en)
|
2005-11-26 |
2016-08-23 |
Natera, Inc. |
System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
|
|
US9428746B2
(en)
|
2007-10-31 |
2016-08-30 |
Akonni Biosystems, Inc. |
Method and kit for purifying nucleic acids
|
|
US7888127B2
(en)
|
2008-01-15 |
2011-02-15 |
Sequenom, Inc. |
Methods for reducing adduct formation for mass spectrometry analysis
|
|
US8476013B2
(en)
|
2008-09-16 |
2013-07-02 |
Sequenom, Inc. |
Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
|
US8962247B2
(en)
|
2008-09-16 |
2015-02-24 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
|
|
WO2010033639A2
(en)
*
|
2008-09-16 |
2010-03-25 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
|
|
EP2516680B1
(en)
|
2009-12-22 |
2016-04-06 |
Sequenom, Inc. |
Processes and kits for identifying aneuploidy
|
|
US11322224B2
(en)
|
2010-05-18 |
2022-05-03 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US11939634B2
(en)
|
2010-05-18 |
2024-03-26 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
CA2798758C
(en)
|
2010-05-18 |
2019-05-07 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US11339429B2
(en)
|
2010-05-18 |
2022-05-24 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US20190010543A1
(en)
|
2010-05-18 |
2019-01-10 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US11332793B2
(en)
|
2010-05-18 |
2022-05-17 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US9677118B2
(en)
|
2014-04-21 |
2017-06-13 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US12152275B2
(en)
|
2010-05-18 |
2024-11-26 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US12221653B2
(en)
|
2010-05-18 |
2025-02-11 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US11332785B2
(en)
|
2010-05-18 |
2022-05-17 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US11408031B2
(en)
|
2010-05-18 |
2022-08-09 |
Natera, Inc. |
Methods for non-invasive prenatal paternity testing
|
|
US11326208B2
(en)
|
2010-05-18 |
2022-05-10 |
Natera, Inc. |
Methods for nested PCR amplification of cell-free DNA
|
|
US10316362B2
(en)
|
2010-05-18 |
2019-06-11 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
CA2824387C
(en)
|
2011-02-09 |
2019-09-24 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US8980553B2
(en)
*
|
2011-04-02 |
2015-03-17 |
New England Biolabs, Inc. |
Methods and compositions for enriching either target polynucleotides or non-target polynucleotides from a mixture of target and non-target polynucleotides
|
|
CN103717750B
(zh)
|
2011-04-29 |
2017-03-08 |
塞昆纳姆股份有限公司 |
少数核酸物质的定量
|
|
US20140235474A1
(en)
|
2011-06-24 |
2014-08-21 |
Sequenom, Inc. |
Methods and processes for non invasive assessment of a genetic variation
|
|
US10196681B2
(en)
|
2011-10-06 |
2019-02-05 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US10424394B2
(en)
|
2011-10-06 |
2019-09-24 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US9367663B2
(en)
|
2011-10-06 |
2016-06-14 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
EP3922731A3
(en)
|
2011-10-06 |
2022-01-05 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US9984198B2
(en)
|
2011-10-06 |
2018-05-29 |
Sequenom, Inc. |
Reducing sequence read count error in assessment of complex genetic variations
|
|
US20140242588A1
(en)
|
2011-10-06 |
2014-08-28 |
Sequenom, Inc |
Methods and processes for non-invasive assessment of genetic variations
|
|
US8688388B2
(en)
|
2011-10-11 |
2014-04-01 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
WO2013055817A1
(en)
|
2011-10-11 |
2013-04-18 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
JP6431769B2
(ja)
|
2012-01-20 |
2018-11-28 |
セクエノム， インコーポレイテッド |
実験条件を要因として含める診断プロセス
|
|
EP3757210B1
(en)
|
2012-03-02 |
2022-08-24 |
Sequenom, Inc. |
Methods for enriching cancer nucleic acid from a biological sample
|
|
US10504613B2
(en)
|
2012-12-20 |
2019-12-10 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US9920361B2
(en)
|
2012-05-21 |
2018-03-20 |
Sequenom, Inc. |
Methods and compositions for analyzing nucleic acid
|
|
DK3663409T3
(da)
|
2012-05-21 |
2021-12-13 |
Sequenom Inc |
Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer
|
|
US10497461B2
(en)
|
2012-06-22 |
2019-12-03 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
EP2872648B1
(en)
|
2012-07-13 |
2019-09-04 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
|
US20140100126A1
(en)
|
2012-08-17 |
2014-04-10 |
Natera, Inc. |
Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
|
|
CA2883463A1
(en)
*
|
2012-08-28 |
2014-03-06 |
Akonni Biosystems Inc. |
Method and kit for purifying nucleic acids
|
|
US10482994B2
(en)
|
2012-10-04 |
2019-11-19 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
CA2887094C
(en)
|
2012-10-04 |
2021-09-07 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US20130309666A1
(en)
|
2013-01-25 |
2013-11-21 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
US20130189684A1
(en)
|
2013-03-12 |
2013-07-25 |
Sequenom, Inc. |
Quantification of cell-specific nucleic acid markers
|
|
US11060145B2
(en)
|
2013-03-13 |
2021-07-13 |
Sequenom, Inc. |
Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus
|
|
US9305756B2
(en)
|
2013-03-13 |
2016-04-05 |
Agena Bioscience, Inc. |
Preparation enhancements and methods of use for MALDI mass spectrometry
|
|
US10930368B2
(en)
|
2013-04-03 |
2021-02-23 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
CN105555968B
(zh)
|
2013-05-24 |
2020-10-23 |
塞昆纳姆股份有限公司 |
遗传变异的非侵入性评估方法和过程
|
|
AU2014278730B2
(en)
*
|
2013-06-13 |
2020-12-10 |
F. Hoffmann-La Roche Ag |
Statistical analysis for non-invasive sex chromosome aneuploidy determination
|
|
PT3011051T
(pt)
|
2013-06-21 |
2019-03-27 |
Sequenom Inc |
Processo para a avaliação não invasiva de alterações genéticas
|
|
KR102846299B1
(ko)
|
2013-10-04 |
2025-08-13 |
시쿼넘, 인코포레이티드 |
유전적 변이의 비침습 평가를 위한 방법 및 프로세스
|
|
EP3055427B1
(en)
|
2013-10-07 |
2018-09-12 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of chromosome alterations
|
|
EP3736344A1
(en)
|
2014-03-13 |
2020-11-11 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
EP3561075A1
(en)
|
2014-04-21 |
2019-10-30 |
Natera, Inc. |
Detecting mutations in tumour biopsies and cell-free samples
|
|
US12492429B2
(en)
|
2014-04-21 |
2025-12-09 |
Natera, Inc. |
Detecting mutations and ploidy in chromosomal segments
|
|
EP2942401A1
(en)
|
2014-05-09 |
2015-11-11 |
Lifecodexx AG |
Detection of DNA that originates from a specific cell-type
|
|
CA2985134A1
(en)
*
|
2014-05-09 |
2015-11-12 |
Sebastian Gromminger |
Detection of dna that originates from a specific cell-type and related methods
|
|
EP2942400A1
(en)
|
2014-05-09 |
2015-11-11 |
Lifecodexx AG |
Multiplex detection of DNA that originates from a specific cell-type
|
|
CA2950731C
(en)
|
2014-05-30 |
2023-04-25 |
Sequenom, Inc. |
Chromosome representation determinations
|
|
US20180173846A1
(en)
|
2014-06-05 |
2018-06-21 |
Natera, Inc. |
Systems and Methods for Detection of Aneuploidy
|
|
EP3760739B1
(en)
|
2014-07-30 |
2025-09-03 |
Sequenom, Inc. |
Methods and processes for non-invasive assessment of genetic variations
|
|
EP3204512B1
(en)
|
2014-10-10 |
2020-05-06 |
Sequenom, Inc. |
Methods for partitioning of genomic sequences
|
|
EP3018213A1
(en)
|
2014-11-04 |
2016-05-11 |
Genesupport SA |
Method for determining the presence of a biological condition by determining total and relative amounts of two different nucleic acids
|
|
EP3292221B1
(en)
*
|
2015-05-06 |
2021-06-23 |
Seracare Life Sciences Inc. |
Liposomal preparations for non-invasive-prenatal or cancer screening
|
|
EP4428863A3
(en)
|
2015-05-11 |
2024-12-11 |
Natera, Inc. |
Methods and compositions for determining ploidy
|
|
JP6643815B2
(ja)
*
|
2015-05-15 |
2020-02-12 |
森永乳業株式会社 |
腸内状態の判定方法、および腸内状態の判定装置
|
|
EP3168309B8
(en)
*
|
2015-11-10 |
2020-06-03 |
Eurofins LifeCodexx GmbH |
Detection of foetal chromosomal aneuploidies using dna regions that are differentially methylated between the foetus and the pregnant female
|
|
JP6564053B2
(ja)
*
|
2015-11-10 |
2019-08-21 |
富士フイルム株式会社 |
細胞間または細胞群間の同一人かどうか、他人かどうか、親子かどうか、または血縁関係かどうかの判定方法
|
|
DK3443119T3
(da)
|
2016-04-15 |
2022-05-23 |
Natera Inc |
Fremgangsmåde til bestemmelse af lunge cancer
|
|
WO2017205826A1
(en)
|
2016-05-27 |
2017-11-30 |
Sequenom, Inc. |
Methods for detecting genetic variations
|
|
CA3030430A1
(en)
|
2016-07-15 |
2018-01-18 |
The Regents Of The University Of California |
Methods of producing nucleic acid libraries
|
|
CA3030894A1
(en)
|
2016-07-27 |
2018-02-01 |
Sequenom, Inc. |
Methods for non-invasive assessment of genomic instability
|
|
WO2018022890A1
(en)
|
2016-07-27 |
2018-02-01 |
Sequenom, Inc. |
Genetic copy number alteration classifications
|
|
WO2018067517A1
(en)
|
2016-10-04 |
2018-04-12 |
Natera, Inc. |
Methods for characterizing copy number variation using proximity-litigation sequencing
|
|
GB201618485D0
(en)
|
2016-11-02 |
2016-12-14 |
Ucl Business Plc |
Method of detecting tumour recurrence
|
|
US10011870B2
(en)
|
2016-12-07 |
2018-07-03 |
Natera, Inc. |
Compositions and methods for identifying nucleic acid molecules
|
|
CA3194621A1
(en)
|
2017-01-20 |
2018-07-26 |
Sequenom, Inc. |
Methods for non-invasive assessment of copy number alterations
|
|
CA3049455C
(en)
|
2017-01-20 |
2023-06-13 |
Sequenom, Inc. |
Sequencing adapter manufacture and use
|
|
EP4235676A3
(en)
|
2017-01-20 |
2023-10-18 |
Sequenom, Inc. |
Methods for non-invasive assessment of genetic alterations
|
|
IL319365A
(en)
|
2017-01-24 |
2025-05-01 |
Sequenom Inc |
Methods and processes for assessing genetic variations
|
|
JP7370862B2
(ja)
|
2017-03-17 |
2023-10-30 |
セクエノム， インコーポレイテッド |
遺伝子モザイク症のための方法およびプロセス
|
|
US12084720B2
(en)
|
2017-12-14 |
2024-09-10 |
Natera, Inc. |
Assessing graft suitability for transplantation
|
|
CA3087001A1
(en)
|
2018-01-12 |
2019-07-18 |
Claret Bioscience, Llc |
Methods and compositions for analyzing nucleic acid
|
|
JP7573443B2
(ja)
|
2018-04-14 |
2024-10-25 |
ナテラ， インコーポレイテッド |
循環腫瘍ｄｎａの個別化された検出を用いる癌検出およびモニタリングの方法
|
|
AU2019280712B2
(en)
|
2018-06-06 |
2025-11-20 |
The Regents Of The University Of California |
Methods of producing nucleic acid libraries and compositions and kits for practicing same
|
|
US12234509B2
(en)
|
2018-07-03 |
2025-02-25 |
Natera, Inc. |
Methods for detection of donor-derived cell-free DNA
|
|
US20200131566A1
(en)
*
|
2018-10-31 |
2020-04-30 |
Guardant Health, Inc. |
Methods, compositions and systems for calibrating epigenetic partitioning assays
|
|
AU2020253471A1
(en)
|
2019-04-05 |
2021-10-14 |
Claret Bioscience, Llc |
Methods and compositions for analyzing nucleic acid
|
|
US20220235404A1
(en)
*
|
2019-05-23 |
2022-07-28 |
American Molecular Laboratories, Inc. |
Methods for detection of rare dna sequences in fecal samples
|
|
EP3980559A1
(en)
|
2019-06-06 |
2022-04-13 |
Natera, Inc. |
Methods for detecting immune cell dna and monitoring immune system
|
|
CN114929893A
(zh)
*
|
2019-06-24 |
2022-08-19 |
齐罗马科德公司 |
差异定量核酸的方法
|
|
CN110734907A
(zh)
*
|
2019-09-17 |
2020-01-31 |
上海凌恩生物科技有限公司 |
一种叶绿体dna的富集方法
|
|
AU2020363787A1
(en)
|
2019-10-09 |
2022-04-21 |
Claret Bioscience, Llc |
Methods and compositions for analyzing nucleic acid
|
|
WO2021087491A1
(en)
|
2019-10-31 |
2021-05-06 |
Sequenom, Inc. |
Application of mosaicism ratio in multifetal gestations and personalized risk assessment
|
|
CA3177270A1
(en)
*
|
2020-05-28 |
2021-12-02 |
Huihong YOU |
Comparing copies of polynucleotides with different features
|
|
WO2021262805A1
(en)
|
2020-06-24 |
2021-12-30 |
Claret Bioscience, Llc |
Methods and compositions for analyzing nucleic acid
|
|
CN111755072B
(zh)
*
|
2020-08-04 |
2021-02-02 |
深圳吉因加医学检验实验室 |
一种同时检测甲基化水平、基因组变异和插入片段的方法及装置
|
|
WO2022076574A1
(en)
|
2020-10-08 |
2022-04-14 |
Claret Bioscience, Llc |
Methods and compositions for analyzing nucleic acid
|
|
US20240026453A1
(en)
*
|
2020-11-19 |
2024-01-25 |
Nucleix Ltd. |
Detecting methylation changes in dna samples using restriction enzymes and high throughput sequencing
|
|
EP4277528B1
(en)
|
2021-01-12 |
2024-11-20 |
Ricoh Company, Ltd. |
Diagnostic support apparatus, diagnostic support method, and diagnostic support program
|
|
WO2024186778A1
(en)
|
2023-03-03 |
2024-09-12 |
Laboratory Corporation Of America Holdings |
Methods and systems for positive cfdna screening on genetic variations using mosaicism ratio
|
|
CN116246704B
(zh)
*
|
2023-05-10 |
2023-08-15 |
广州精科生物技术有限公司 |
用于胎儿无创产前检测的系统
|
|
AU2024271681A1
(en)
|
2023-05-15 |
2025-09-18 |
Laboratory Corporation Of America Holdings |
Machine-learning approaches to pan-cancer screening in whole genome sequencing
|
|
WO2025113619A1
(en)
*
|
2023-11-29 |
2025-06-05 |
Centre For Novostics |
Enrichment of clinically-relevant nucleic acids
|