JP2014193889A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014193889A5 JP2014193889A5 JP2014099667A JP2014099667A JP2014193889A5 JP 2014193889 A5 JP2014193889 A5 JP 2014193889A5 JP 2014099667 A JP2014099667 A JP 2014099667A JP 2014099667 A JP2014099667 A JP 2014099667A JP 2014193889 A5 JP2014193889 A5 JP 2014193889A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently
- substituted
- hal
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07105980.2 | 2007-04-11 | ||
| EP07105980 | 2007-04-11 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010502521A Division JP5710246B2 (ja) | 2007-04-11 | 2008-04-11 | 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014193889A JP2014193889A (ja) | 2014-10-09 |
| JP2014193889A5 true JP2014193889A5 (enExample) | 2015-03-19 |
| JP5876527B2 JP5876527B2 (ja) | 2016-03-02 |
Family
ID=39683755
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010502521A Expired - Fee Related JP5710246B2 (ja) | 2007-04-11 | 2008-04-11 | 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体 |
| JP2014099667A Expired - Fee Related JP5876527B2 (ja) | 2007-04-11 | 2014-05-13 | 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010502521A Expired - Fee Related JP5710246B2 (ja) | 2007-04-11 | 2008-04-11 | 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20100143249A1 (enExample) |
| EP (1) | EP2146995A1 (enExample) |
| JP (2) | JP5710246B2 (enExample) |
| KR (2) | KR20150140415A (enExample) |
| CN (1) | CN101646672B (enExample) |
| AU (1) | AU2008237935B2 (enExample) |
| CA (1) | CA2670385C (enExample) |
| EA (1) | EA200901344A1 (enExample) |
| IL (1) | IL201250A0 (enExample) |
| WO (1) | WO2008125618A1 (enExample) |
| ZA (1) | ZA200903483B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008125618A1 (en) * | 2007-04-11 | 2008-10-23 | Merck Eprova Ag | Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy |
| US8236284B1 (en) * | 2008-04-02 | 2012-08-07 | University Of Central Florida Research Foundation, Inc. | Multimodal, multifunctional polymer coated nanoparticles |
| FR2942227B1 (fr) * | 2009-02-13 | 2011-04-15 | Guerbet Sa | Utilisation de tampons pour la complexation de radionucleides |
| WO2011084571A2 (en) | 2009-12-16 | 2011-07-14 | Mallinckrodt Inc. | Azide derivatives for phototherapy |
| WO2013024035A1 (en) * | 2011-08-17 | 2013-02-21 | Merck & Cie | Folate conjugates of albumin-binding entities |
| EA201401225A1 (ru) | 2012-05-08 | 2015-04-30 | Мерк Э Сие | F-меченые аналоги фолата/антифолата |
| EP3253732A4 (en) * | 2015-02-06 | 2018-08-29 | Cempra Pharmaceuticals, Inc. | 4-azidobutylamines and processes for preparing |
| JP7391847B2 (ja) | 2019-06-20 | 2023-12-05 | クワッド マイナーズ | ネットワークフォレンジックシステム及びこれを用いたネットワークフォレンジック方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6093382A (en) * | 1998-05-16 | 2000-07-25 | Bracco Research Usa Inc. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| ATE427948T1 (de) | 2001-04-24 | 2009-04-15 | Purdue Research Foundation | Folat-mimetika und deren folatrezeptorbindende konjugate |
| ATE448799T1 (de) * | 2002-05-06 | 2009-12-15 | Endocyte Inc | Folatrezeptor gerichtete bildgebende konjugate |
| BRPI0409906A (pt) * | 2003-04-29 | 2006-04-25 | Univ Zuerich | l-histidina protegida, metálica e orgánica derivatizada em nepsilon e/ou nalfa para acoplar ás biomoléculas para marcação altamente eficiente com [m(oh2)3(co)3]+ por coordenação de fac |
| US9265746B2 (en) * | 2006-05-31 | 2016-02-23 | Merck & Cie | Method for cell-specific targeting |
| WO2008125618A1 (en) * | 2007-04-11 | 2008-10-23 | Merck Eprova Ag | Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy |
-
2008
- 2008-04-11 WO PCT/EP2008/054409 patent/WO2008125618A1/en not_active Ceased
- 2008-04-11 CA CA2670385A patent/CA2670385C/en not_active Expired - Fee Related
- 2008-04-11 AU AU2008237935A patent/AU2008237935B2/en not_active Ceased
- 2008-04-11 KR KR1020157034215A patent/KR20150140415A/ko not_active Withdrawn
- 2008-04-11 CN CN200880002741.6A patent/CN101646672B/zh not_active Expired - Fee Related
- 2008-04-11 KR KR1020097023300A patent/KR101605426B1/ko not_active Expired - Fee Related
- 2008-04-11 JP JP2010502521A patent/JP5710246B2/ja not_active Expired - Fee Related
- 2008-04-11 EA EA200901344A patent/EA200901344A1/ru unknown
- 2008-04-11 EP EP08736122A patent/EP2146995A1/en not_active Withdrawn
- 2008-04-11 US US12/595,147 patent/US20100143249A1/en not_active Abandoned
-
2009
- 2009-05-20 ZA ZA200903483A patent/ZA200903483B/xx unknown
- 2009-09-30 IL IL201250A patent/IL201250A0/en not_active IP Right Cessation
-
2014
- 2014-05-13 JP JP2014099667A patent/JP5876527B2/ja not_active Expired - Fee Related
-
2016
- 2016-11-22 US US15/358,787 patent/US20170128599A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014193889A5 (enExample) | ||
| US11951109B2 (en) | EZH2 inhibitors for treating lymphoma | |
| US10201617B2 (en) | 3-substituted piperidine-2, 6-diones and non-covalent complexes with albumin | |
| AU2018353150B2 (en) | Methods of using EHMT2 inhibitors in treating or preventing blood disorders | |
| US11147819B2 (en) | EZH2 inhibitors for treating cancer | |
| KR102117982B1 (ko) | 암 치료용 병용 요법 | |
| ES2868748T3 (es) | Compuesto de piridina | |
| JP2021130700A (ja) | 癌を処置するための併用療法 | |
| JP7208898B2 (ja) | 癌を処置するための併用療法 | |
| JP2024001203A (ja) | 癌を処置するための併用療法 | |
| AU2020315210B2 (en) | Imidazo[4,5-C]pyridine derivatives as Toll-like receptor agonists | |
| JP6538656B2 (ja) | 5’−ヌクレオチダーゼ阻害剤およびその治療的使用 | |
| CN105683166A (zh) | 取代的嘧啶Bmi-1抑制剂 | |
| EA039630B1 (ru) | N-замещенные индольные производные | |
| CA3107548A1 (en) | Smad3 inhibitors | |
| Ge et al. | Synthesis and biological evaluation of 6-fluoro-3-phenyl-7-piperazinyl quinolone derivatives as potential topoisomerase I inhibitors | |
| KR20080004495A (ko) | 암을 치료하기 위한 조합물, 방법 및 조성물 | |
| Roy et al. | Synthesis of N-alkyl substituted bioactive indolocarbazoles related to Gö6976 | |
| CN108699030B (zh) | 一类取代的氨基六元氮杂环类化合物及其制备和用途 | |
| CA2884832C (en) | Means and method for treating solid tumours | |
| CA2602199A1 (en) | Heteroaryl urea derivatives useful for inhibiting chk1 | |
| JP2022520907A (ja) | Nurr1受容体調節因子 | |
| AR075603A1 (es) | Derivados de tetrahidropirazolo(3,4-c)isoquinolin-5-amina | |
| US11548891B1 (en) | Quaternary ammonium salts of phenanthroindolizidine and phenanthroquinolizidine alkaloids as hypoxia-targeted anticancer agents | |
| Wang et al. | The first design and synthesis of [11C] MKC-1 ([11C] Ro 31-7453), a new potential PET cancer imaging agent |