JP2014193889A5 - - Google Patents

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Publication number
JP2014193889A5
JP2014193889A5 JP2014099667A JP2014099667A JP2014193889A5 JP 2014193889 A5 JP2014193889 A5 JP 2014193889A5 JP 2014099667 A JP2014099667 A JP 2014099667A JP 2014099667 A JP2014099667 A JP 2014099667A JP 2014193889 A5 JP2014193889 A5 JP 2014193889A5
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JP
Japan
Prior art keywords
alkyl
independently
substituted
hal
alkoxy
Prior art date
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Granted
Application number
JP2014099667A
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English (en)
Japanese (ja)
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JP2014193889A (ja
JP5876527B2 (ja
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Application filed filed Critical
Publication of JP2014193889A publication Critical patent/JP2014193889A/ja
Publication of JP2014193889A5 publication Critical patent/JP2014193889A5/ja
Application granted granted Critical
Publication of JP5876527B2 publication Critical patent/JP5876527B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014099667A 2007-04-11 2014-05-13 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体 Expired - Fee Related JP5876527B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07105980.2 2007-04-11
EP07105980 2007-04-11

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2010502521A Division JP5710246B2 (ja) 2007-04-11 2008-04-11 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体

Publications (3)

Publication Number Publication Date
JP2014193889A JP2014193889A (ja) 2014-10-09
JP2014193889A5 true JP2014193889A5 (enExample) 2015-03-19
JP5876527B2 JP5876527B2 (ja) 2016-03-02

Family

ID=39683755

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010502521A Expired - Fee Related JP5710246B2 (ja) 2007-04-11 2008-04-11 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体
JP2014099667A Expired - Fee Related JP5876527B2 (ja) 2007-04-11 2014-05-13 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2010502521A Expired - Fee Related JP5710246B2 (ja) 2007-04-11 2008-04-11 診断用画像及び放射線治療用の葉酸複合体及び対応する金属キレート錯体

Country Status (11)

Country Link
US (2) US20100143249A1 (enExample)
EP (1) EP2146995A1 (enExample)
JP (2) JP5710246B2 (enExample)
KR (2) KR20150140415A (enExample)
CN (1) CN101646672B (enExample)
AU (1) AU2008237935B2 (enExample)
CA (1) CA2670385C (enExample)
EA (1) EA200901344A1 (enExample)
IL (1) IL201250A0 (enExample)
WO (1) WO2008125618A1 (enExample)
ZA (1) ZA200903483B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008125618A1 (en) * 2007-04-11 2008-10-23 Merck Eprova Ag Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy
US8236284B1 (en) * 2008-04-02 2012-08-07 University Of Central Florida Research Foundation, Inc. Multimodal, multifunctional polymer coated nanoparticles
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
WO2011084571A2 (en) 2009-12-16 2011-07-14 Mallinckrodt Inc. Azide derivatives for phototherapy
WO2013024035A1 (en) * 2011-08-17 2013-02-21 Merck & Cie Folate conjugates of albumin-binding entities
EA201401225A1 (ru) 2012-05-08 2015-04-30 Мерк Э Сие F-меченые аналоги фолата/антифолата
EP3253732A4 (en) * 2015-02-06 2018-08-29 Cempra Pharmaceuticals, Inc. 4-azidobutylamines and processes for preparing
JP7391847B2 (ja) 2019-06-20 2023-12-05 クワッド マイナーズ ネットワークフォレンジックシステム及びこれを用いたネットワークフォレンジック方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093382A (en) * 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
ATE427948T1 (de) 2001-04-24 2009-04-15 Purdue Research Foundation Folat-mimetika und deren folatrezeptorbindende konjugate
ATE448799T1 (de) * 2002-05-06 2009-12-15 Endocyte Inc Folatrezeptor gerichtete bildgebende konjugate
BRPI0409906A (pt) * 2003-04-29 2006-04-25 Univ Zuerich l-histidina protegida, metálica e orgánica derivatizada em nepsilon e/ou nalfa para acoplar ás biomoléculas para marcação altamente eficiente com [m(oh2)3(co)3]+ por coordenação de fac
US9265746B2 (en) * 2006-05-31 2016-02-23 Merck & Cie Method for cell-specific targeting
WO2008125618A1 (en) * 2007-04-11 2008-10-23 Merck Eprova Ag Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy

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