AU2008237935B2 - Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy - Google Patents
Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy Download PDFInfo
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- AU2008237935B2 AU2008237935B2 AU2008237935A AU2008237935A AU2008237935B2 AU 2008237935 B2 AU2008237935 B2 AU 2008237935B2 AU 2008237935 A AU2008237935 A AU 2008237935A AU 2008237935 A AU2008237935 A AU 2008237935A AU 2008237935 B2 AU2008237935 B2 AU 2008237935B2
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- alkyl
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- 238000001959 radiotherapy Methods 0.000 title claims description 11
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Classifications
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
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- G01—MEASURING; TESTING
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07105980.2 | 2007-04-11 | ||
| EP07105980 | 2007-04-11 | ||
| PCT/EP2008/054409 WO2008125618A1 (en) | 2007-04-11 | 2008-04-11 | Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy |
Publications (2)
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|---|---|
| AU2008237935A1 AU2008237935A1 (en) | 2008-10-23 |
| AU2008237935B2 true AU2008237935B2 (en) | 2014-03-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008237935A Ceased AU2008237935B2 (en) | 2007-04-11 | 2008-04-11 | Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20100143249A1 (enExample) |
| EP (1) | EP2146995A1 (enExample) |
| JP (2) | JP5710246B2 (enExample) |
| KR (2) | KR20150140415A (enExample) |
| CN (1) | CN101646672B (enExample) |
| AU (1) | AU2008237935B2 (enExample) |
| CA (1) | CA2670385C (enExample) |
| EA (1) | EA200901344A1 (enExample) |
| IL (1) | IL201250A0 (enExample) |
| WO (1) | WO2008125618A1 (enExample) |
| ZA (1) | ZA200903483B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150140415A (ko) * | 2007-04-11 | 2015-12-15 | 메르크 앤드 씨에 | 진단 이미징 및 방사선치료에 사용하기 위한 폴레이트-컨쥬게이트 및 대응하는 금속-킬레이트 착물 |
| US8236284B1 (en) * | 2008-04-02 | 2012-08-07 | University Of Central Florida Research Foundation, Inc. | Multimodal, multifunctional polymer coated nanoparticles |
| FR2942227B1 (fr) * | 2009-02-13 | 2011-04-15 | Guerbet Sa | Utilisation de tampons pour la complexation de radionucleides |
| WO2011084571A2 (en) | 2009-12-16 | 2011-07-14 | Mallinckrodt Inc. | Azide derivatives for phototherapy |
| PT2766364T (pt) * | 2011-08-17 | 2024-09-24 | Merck & Cie | Conjugados de folato de entidades de ligação a albumina |
| AU2013258027B2 (en) | 2012-05-08 | 2017-11-30 | Merck & Cie | 18F-labelled follate/antifolate analogues |
| JP2018504422A (ja) * | 2015-02-06 | 2018-02-15 | センプラ ファーマシューティカルズ，インコーポレイテッド | ４−アジドブチルアミンおよびその調製方法 |
| WO2020256210A1 (ko) | 2019-06-20 | 2020-12-24 | 주식회사 쿼드마이너 | 네트워크 포렌식 시스템 및 이를 이용한 네트워크 포렌식 방법 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999059640A2 (en) * | 1998-05-16 | 1999-11-25 | Bracco International B.V. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| WO2003092742A1 (en) * | 2002-05-06 | 2003-11-13 | Endocyte, Inc. | Vitamin-targeted imaging agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1389209B1 (en) * | 2001-04-24 | 2009-04-08 | Purdue Research Foundation | Folate mimetics and folate-receptor binding conjugates thereof |
| AU2004235488A1 (en) * | 2003-04-29 | 2004-11-11 | Universitat Zurich | Nepsilon and/or nalpha derivatized, metal and organic protected l-histidine for coupling to biomolecules for highly efficient labeling with [M(OH2)3(CO)3]+ by fac coordination |
| US9265746B2 (en) * | 2006-05-31 | 2016-02-23 | Merck & Cie | Method for cell-specific targeting |
| KR20150140415A (ko) * | 2007-04-11 | 2015-12-15 | 메르크 앤드 씨에 | 진단 이미징 및 방사선치료에 사용하기 위한 폴레이트-컨쥬게이트 및 대응하는 금속-킬레이트 착물 |
-
2008
- 2008-04-11 KR KR1020157034215A patent/KR20150140415A/ko not_active Withdrawn
- 2008-04-11 CA CA2670385A patent/CA2670385C/en not_active Expired - Fee Related
- 2008-04-11 AU AU2008237935A patent/AU2008237935B2/en not_active Ceased
- 2008-04-11 CN CN200880002741.6A patent/CN101646672B/zh not_active Expired - Fee Related
- 2008-04-11 EA EA200901344A patent/EA200901344A1/ru unknown
- 2008-04-11 JP JP2010502521A patent/JP5710246B2/ja not_active Expired - Fee Related
- 2008-04-11 US US12/595,147 patent/US20100143249A1/en not_active Abandoned
- 2008-04-11 WO PCT/EP2008/054409 patent/WO2008125618A1/en not_active Ceased
- 2008-04-11 KR KR1020097023300A patent/KR101605426B1/ko not_active Expired - Fee Related
- 2008-04-11 EP EP08736122A patent/EP2146995A1/en not_active Withdrawn
-
2009
- 2009-05-20 ZA ZA200903483A patent/ZA200903483B/xx unknown
- 2009-09-30 IL IL201250A patent/IL201250A0/en not_active IP Right Cessation
-
2014
- 2014-05-13 JP JP2014099667A patent/JP5876527B2/ja not_active Expired - Fee Related
-
2016
- 2016-11-22 US US15/358,787 patent/US20170128599A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999059640A2 (en) * | 1998-05-16 | 1999-11-25 | Bracco International B.V. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| US20010004454A1 (en) * | 1998-05-16 | 2001-06-21 | Wedeking Paul W. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| WO2003092742A1 (en) * | 2002-05-06 | 2003-11-13 | Endocyte, Inc. | Vitamin-targeted imaging agents |
Non-Patent Citations (2)
| Title |
|---|
| KE CHUN-YEN et al: Nuclear Medicine & Biology, 2003, 30(8), 811-817 * |
| MINDT T. L. et al: J American Chem. Soc., 2006, 128, 15096-15097 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008125618A1 (en) | 2008-10-23 |
| CA2670385A1 (en) | 2008-10-23 |
| CN101646672B (zh) | 2015-08-19 |
| EA200901344A1 (ru) | 2010-04-30 |
| US20170128599A1 (en) | 2017-05-11 |
| AU2008237935A1 (en) | 2008-10-23 |
| CN101646672A (zh) | 2010-02-10 |
| CA2670385C (en) | 2016-01-12 |
| ZA200903483B (en) | 2010-04-28 |
| EP2146995A1 (en) | 2010-01-27 |
| JP2014193889A (ja) | 2014-10-09 |
| IL201250A0 (en) | 2010-05-31 |
| KR20150140415A (ko) | 2015-12-15 |
| HK1138571A1 (zh) | 2010-08-27 |
| US20100143249A1 (en) | 2010-06-10 |
| KR20100016330A (ko) | 2010-02-12 |
| KR101605426B1 (ko) | 2016-03-22 |
| JP2010523626A (ja) | 2010-07-15 |
| JP5876527B2 (ja) | 2016-03-02 |
| JP5710246B2 (ja) | 2015-04-30 |
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| Publication | Publication Date | Title |
|---|---|---|
| AU2008237932B2 (en) | 18 F-labelled folates | |
| AU2008237935B2 (en) | Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy | |
| AU2013258027B2 (en) | 18F-labelled follate/antifolate analogues | |
| US9771368B2 (en) | 18F-labelled folates | |
| HK1138571B (en) | Folate-conjugates and corresponding metal-chelate complexes for use in diagnostic imaging and radiotherapy |
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| Date | Code | Title | Description |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |