JP2014100611A5 - - Google Patents
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- Publication number
- JP2014100611A5 JP2014100611A5 JP2014048739A JP2014048739A JP2014100611A5 JP 2014100611 A5 JP2014100611 A5 JP 2014100611A5 JP 2014048739 A JP2014048739 A JP 2014048739A JP 2014048739 A JP2014048739 A JP 2014048739A JP 2014100611 A5 JP2014100611 A5 JP 2014100611A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- poloxamer
- purified
- thermosensitive polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 46
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims 11
- 229920000642 polymer Polymers 0.000 claims 10
- 229920001983 poloxamer Polymers 0.000 claims 6
- 229960000502 poloxamer Drugs 0.000 claims 5
- 230000001052 transient effect Effects 0.000 claims 5
- 229920002359 Tetronic® Polymers 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 210000003734 kidney Anatomy 0.000 claims 4
- 229920001992 poloxamer 407 Polymers 0.000 claims 4
- 229940044476 poloxamer 407 Drugs 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- 230000007704 transition Effects 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 229920002517 Poloxamer 338 Polymers 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 229920001993 poloxamer 188 Polymers 0.000 claims 2
- 229940044519 poloxamer 188 Drugs 0.000 claims 2
- 229920001987 poloxamine Polymers 0.000 claims 2
- BCKXLBQYZLBQEK-KVVVOXFISA-M Sodium oleate Chemical group [Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O BCKXLBQYZLBQEK-KVVVOXFISA-M 0.000 claims 1
- 229910052768 actinide Inorganic materials 0.000 claims 1
- 150000001255 actinides Chemical class 0.000 claims 1
- 229940035676 analgesics Drugs 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 229940124599 anti-inflammatory drug Drugs 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 229940124350 antibacterial drug Drugs 0.000 claims 1
- -1 antibacterial drugs Substances 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 229940044683 chemotherapy drug Drugs 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000009977 dual effect Effects 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 230000023597 hemostasis Effects 0.000 claims 1
- 229910052747 lanthanoid Inorganic materials 0.000 claims 1
- 150000002602 lanthanoids Chemical class 0.000 claims 1
- 238000013059 nephrectomy Methods 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 239000002907 paramagnetic material Substances 0.000 claims 1
- 230000010412 perfusion Effects 0.000 claims 1
- 239000002504 physiological saline solution Substances 0.000 claims 1
- BTURAGWYSMTVOW-UHFFFAOYSA-M sodium dodecanoate Chemical compound [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 claims 1
- 229940082004 sodium laurate Drugs 0.000 claims 1
- FIWQZURFGYXCEO-UHFFFAOYSA-M sodium;decanoate Chemical compound [Na+].CCCCCCCCCC([O-])=O FIWQZURFGYXCEO-UHFFFAOYSA-M 0.000 claims 1
- 229910052723 transition metal Inorganic materials 0.000 claims 1
- 150000003624 transition metals Chemical class 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87406206P | 2006-12-11 | 2006-12-11 | |
| US60/874,062 | 2006-12-11 | ||
| US89399307P | 2007-03-09 | 2007-03-09 | |
| US60/893,993 | 2007-03-09 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541532A Division JP2010512230A (ja) | 2006-12-11 | 2007-12-11 | 灌流臓器止血法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016089234A Division JP2016135365A (ja) | 2006-12-11 | 2016-04-27 | 灌流臓器止血法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014100611A JP2014100611A (ja) | 2014-06-05 |
| JP2014100611A5 true JP2014100611A5 (enExample) | 2014-07-17 |
| JP5931943B2 JP5931943B2 (ja) | 2016-06-08 |
Family
ID=39512452
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541532A Pending JP2010512230A (ja) | 2006-12-11 | 2007-12-11 | 灌流臓器止血法 |
| JP2014048739A Expired - Fee Related JP5931943B2 (ja) | 2006-12-11 | 2014-03-12 | 灌流臓器止血法 |
| JP2016089234A Pending JP2016135365A (ja) | 2006-12-11 | 2016-04-27 | 灌流臓器止血法 |
| JP2017187859A Pending JP2018000996A (ja) | 2006-12-11 | 2017-09-28 | 灌流臓器止血法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541532A Pending JP2010512230A (ja) | 2006-12-11 | 2007-12-11 | 灌流臓器止血法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016089234A Pending JP2016135365A (ja) | 2006-12-11 | 2016-04-27 | 灌流臓器止血法 |
| JP2017187859A Pending JP2018000996A (ja) | 2006-12-11 | 2017-09-28 | 灌流臓器止血法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US20080181952A1 (enExample) |
| EP (1) | EP2094169A4 (enExample) |
| JP (4) | JP2010512230A (enExample) |
| CN (2) | CN105251035A (enExample) |
| WO (1) | WO2008073938A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2866133B2 (ja) | 1989-07-25 | 1999-03-08 | 株式会社リコー | 液体噴射記録装置及び方法 |
| JP2989243B2 (ja) | 1990-10-16 | 1999-12-13 | 株式会社リコー | 液体噴射記録方法及び装置 |
| JP2989242B2 (ja) | 1990-10-16 | 1999-12-13 | 株式会社リコー | 液体噴射記録方法及び装置 |
| JP2957676B2 (ja) | 1990-10-16 | 1999-10-06 | 株式会社リコー | 液体噴射記録装置及び方法 |
| WO2008018892A2 (en) * | 2005-12-22 | 2008-02-14 | Pluromed, Inc. | Methods and kits for treating lacerations and puncture wounds using inverse thermosensitive polymers |
| US8197499B2 (en) | 2006-06-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
| EP2034906A4 (en) | 2006-06-21 | 2010-07-28 | Univ Leland Stanford Junior | COMPOSITIONS AND METHODS FOR CONNECTING NON-ASSOCIATED LUMENS |
| US8608760B2 (en) * | 2006-06-21 | 2013-12-17 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
| KR101428122B1 (ko) | 2006-12-15 | 2014-08-07 | 라이프본드 엘티디. | 젤라틴-트랜스글루타미나아제 지혈 드레싱 및 실란트 |
| US20080208163A1 (en) * | 2007-02-22 | 2008-08-28 | Pluromed, Inc. | Use of Reverse Thermosensitive Polymers to Control Biological Fluid Flow Following a Medical Procedure |
| BRPI0820785A2 (pt) * | 2007-12-20 | 2015-06-16 | Tautona Group L P | Composições e métodos para unir lúmens não unidos |
| US8394795B2 (en) * | 2008-02-29 | 2013-03-12 | Array Biopharma Inc. | Pyrazole [3, 4-B] pyridine Raf inhibitors |
| CN106037857A (zh) * | 2008-02-29 | 2016-10-26 | 普拉罗美德公司 | 通过加热热敏聚合物进行的局部栓塞 |
| BRPI0912482A2 (pt) | 2008-05-14 | 2020-08-18 | Otonomy, Inc | composições de corticosteróide de liberação controlada e métodos para o tratamento de distúrbios auriculares |
| JP5450612B2 (ja) | 2008-06-18 | 2014-03-26 | ライフボンド リミテッド | 改良された架橋組成物 |
| US8318817B2 (en) | 2008-07-21 | 2012-11-27 | Otonomy, Inc. | Controlled release antimicrobial compositions and methods for the treatment of otic disorders |
| US8563037B2 (en) * | 2009-02-06 | 2013-10-22 | Tautona Group, L.P. | Compositions and methods for joining non-conjoined lumens |
| EP2480204B1 (en) * | 2009-09-22 | 2013-11-06 | Vlife Sciences Technologies Pvt Ltd. | Topical formulation for diabetic foot ulcers |
| EP2490722A4 (en) * | 2009-10-21 | 2014-03-05 | Otonomy Inc | MODULATION OF THE TEMPERATURE OF GELIFICATION OF FORMULATIONS CONTAINING POLOXAMERS |
| BR112012015029A2 (pt) | 2009-12-22 | 2017-06-27 | Lifebond Ltd | matriz reticulada, método para controlar a formação de uma matriz, método ou matriz, método para vedar um tecido contra vazamento de um fluído corporal, agente hemostático ou vedante cirúrgico, composição para vedar um ferimento, uso da composição, composição para um veículo para entrega localizada de fármaco, composição para engenharia de tecido, e método para modificar uma composição |
| EP2600910B1 (en) | 2010-08-05 | 2016-01-20 | Lifebond Ltd | Dry composition wound dressings and adhesives |
| US9060749B2 (en) | 2011-08-12 | 2015-06-23 | Boston Scientific Scimed, Inc. | Methods, compositions and kits for performing anastomosis procedures in conjunction with a radical prostatectomy procedure |
| US9433699B2 (en) | 2011-11-21 | 2016-09-06 | Innotherapy Inc. | Hydrogel comprising catechol group-coupled chitosan or polyamine and poloxamer comprising thiol group coupled to end thereof, preparation method thereof, and hemostat using same |
| DE102013211316A1 (de) * | 2013-06-17 | 2014-12-18 | Aesculap Ag | Hämostyptikum |
| US9486405B2 (en) | 2013-08-27 | 2016-11-08 | Otonomy, Inc. | Methods for the treatment of pediatric otic disorders |
| ITMI20131924A1 (it) * | 2013-11-20 | 2015-05-21 | Cosmo Technologies Ltd | Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica |
| ITMI20131927A1 (it) * | 2013-11-20 | 2015-05-21 | Cosmo Technologies Ltd | Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection. emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica |
| JP6562902B2 (ja) * | 2014-03-28 | 2019-08-21 | テルモ株式会社 | 生体血管内血液置換用液体、生体血管内血液置換用液体製剤およびプレフィルドシリンジ |
| AR102147A1 (es) * | 2014-10-01 | 2017-02-08 | Als Mountain Llc | Composición farmacéutica que comprende aspirina, metformina y serotonina con agente tensioactivo no iónico |
| US20170274189A1 (en) * | 2016-03-24 | 2017-09-28 | Ethicon, Inc. | Single lumen balloon delivery catheter with lumen bypass at balloon |
| CN108714243A (zh) * | 2017-06-08 | 2018-10-30 | 重庆大学 | 用于脑出血术后止血的植入剂及其制备方法 |
| WO2019163012A1 (ja) * | 2018-02-21 | 2019-08-29 | 国立大学法人信州大学 | 液体塞栓剤組成物 |
| EP4233914A3 (en) | 2018-03-16 | 2023-10-18 | Critical Innovations, LLC | Systems and methods relating to medical applications of synthetic polymer formulations |
| US11998654B2 (en) | 2018-07-12 | 2024-06-04 | Bard Shannon Limited | Securing implants and medical devices |
| CN112138204A (zh) * | 2019-06-26 | 2020-12-29 | 广东博与再生医学有限公司 | 骨止血材料 |
| JP7546265B2 (ja) * | 2020-05-22 | 2024-09-06 | ウェトラブホールディング株式会社 | 生体組織用二液型バインダーおよび生体組織用二液型充填材 |
| CN111632189B (zh) * | 2020-05-27 | 2021-12-14 | 深圳先进技术研究院 | 基于海洋源明胶的可注射水凝胶止血剂及应用和应用方法 |
| US12410293B2 (en) | 2022-11-07 | 2025-09-09 | Critical Innovations Llc | Systems and methods relating to medical applications of inverse thermosensitive polymer foam formulations |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3889685A (en) * | 1973-11-02 | 1975-06-17 | Cutter Lab | Tubular unit with vessel engaging cuff structure |
| US4188373A (en) * | 1976-02-26 | 1980-02-12 | Cooper Laboratories, Inc. | Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes |
| US4168708A (en) * | 1977-04-20 | 1979-09-25 | Medical Engineering Corp. | Blood vessel occlusion means suitable for use in anastomosis |
| US4474751A (en) * | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Ophthalmic drug delivery system utilizing thermosetting gels |
| US4478822A (en) * | 1983-05-16 | 1984-10-23 | Merck & Co., Inc. | Drug delivery system utilizing thermosetting gels |
| US5567859A (en) * | 1991-03-19 | 1996-10-22 | Cytrx Corporation | Polyoxypropylene/polyoxyethylene copolymers with improved biological activity |
| US5843156A (en) * | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
| US4946463A (en) * | 1989-04-10 | 1990-08-07 | Pioneering Technologies, Inc. | Vessel occluder |
| ATE130517T1 (de) * | 1990-08-08 | 1995-12-15 | Takeda Chemical Industries Ltd | Intravaskulär embolisierendes mittel mit gehalt an einem die angiogenesis hemmenden stoff. |
| CN1069741A (zh) * | 1991-03-19 | 1993-03-10 | 西特克斯公司 | 具有改进的生物活性的聚氧丙烯/聚氧乙烯共聚物 |
| US5696298A (en) * | 1991-03-19 | 1997-12-09 | Cytrx Corporation | Polyoxypropylene/polyoxyethylene copolymers with improved biological activity |
| US5939485A (en) * | 1995-06-19 | 1999-08-17 | Medlogic Global Corporation | Responsive polymer networks and methods of their use |
| US5800711A (en) * | 1996-10-18 | 1998-09-01 | Mdv Technologies, Inc. | Process for the fractionation of polyoxyalkylene block copolymers |
| US6120751A (en) * | 1997-03-21 | 2000-09-19 | Imarx Pharmaceutical Corp. | Charged lipids and uses for the same |
| US7485317B1 (en) * | 1999-02-05 | 2009-02-03 | The Regents Of The University Of California | Thermo-reversible polymer for intralumenal implant |
| CN101708165A (zh) * | 2000-03-24 | 2010-05-19 | 生物领域医疗公司 | 用于主动栓塞术的微球体 |
| US6761824B2 (en) * | 2000-08-17 | 2004-07-13 | Reeve Lorraine E | Process for the fractionation of polymers |
| US7838699B2 (en) * | 2002-05-08 | 2010-11-23 | Biosphere Medical | Embolization using degradable crosslinked hydrogels |
| JP4909071B2 (ja) * | 2003-03-24 | 2012-04-04 | プルーローメッド, インコーポレイテッド | 逆感熱性ポリマーを使用する一時的な塞栓形成 |
| JP4898447B2 (ja) * | 2003-10-14 | 2012-03-14 | プルーロームド インコーポレイテッド | 結石破砕術の際の腎結石破片の閉じ込め |
| US7700086B2 (en) * | 2003-11-06 | 2010-04-20 | Pluromed, Inc. | Internal clamp for surgical procedures |
| US20060253099A1 (en) * | 2005-04-21 | 2006-11-09 | Medtronic Vascular, Inc. | Guiding catheter with resiliently compressible occluder |
| PT2601972E (pt) * | 2005-05-02 | 2015-02-09 | Gen Hospital Corp | Tratamento de litíase renal sem litotripsia |
-
2007
- 2007-12-11 US US11/954,109 patent/US20080181952A1/en not_active Abandoned
- 2007-12-11 JP JP2009541532A patent/JP2010512230A/ja active Pending
- 2007-12-11 WO PCT/US2007/087079 patent/WO2008073938A2/en not_active Ceased
- 2007-12-11 CN CN201510386368.0A patent/CN105251035A/zh active Pending
- 2007-12-11 CN CN200780051223A patent/CN101677822A/zh active Pending
- 2007-12-11 EP EP07865497.7A patent/EP2094169A4/en not_active Withdrawn
-
2014
- 2014-03-12 JP JP2014048739A patent/JP5931943B2/ja not_active Expired - Fee Related
- 2014-03-25 US US14/225,299 patent/US20140205542A1/en not_active Abandoned
-
2016
- 2016-03-18 US US15/074,432 patent/US20170043050A1/en not_active Abandoned
- 2016-04-27 JP JP2016089234A patent/JP2016135365A/ja active Pending
-
2017
- 2017-06-13 US US15/621,704 patent/US20180117211A1/en not_active Abandoned
- 2017-09-28 JP JP2017187859A patent/JP2018000996A/ja active Pending
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