JP2010512230A5 - - Google Patents
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- JP2010512230A5 JP2010512230A5 JP2009541532A JP2009541532A JP2010512230A5 JP 2010512230 A5 JP2010512230 A5 JP 2010512230A5 JP 2009541532 A JP2009541532 A JP 2009541532A JP 2009541532 A JP2009541532 A JP 2009541532A JP 2010512230 A5 JP2010512230 A5 JP 2010512230A5
- Authority
- JP
- Japan
- Prior art keywords
- transient gel
- agent according
- transient
- agent
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000499 gel Substances 0.000 claims 44
- 239000003814 drug Substances 0.000 claims 42
- 230000001052 transient effect Effects 0.000 claims 37
- 239000003795 chemical substances by application Substances 0.000 claims 33
- 229940079593 drug Drugs 0.000 claims 25
- 229920000642 polymer Polymers 0.000 claims 22
- 239000000203 mixture Substances 0.000 claims 14
- 230000007704 transition Effects 0.000 claims 13
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical group C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims 12
- 210000000056 organ Anatomy 0.000 claims 10
- 229920001983 poloxamer Polymers 0.000 claims 8
- 229920002148 Gellan gum Polymers 0.000 claims 6
- 229960000502 poloxamer Drugs 0.000 claims 6
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 4
- 229920002359 Tetronic® Polymers 0.000 claims 4
- 235000010443 alginic acid Nutrition 0.000 claims 4
- 229920000615 alginic acid Polymers 0.000 claims 4
- 229910052791 calcium Inorganic materials 0.000 claims 4
- 239000011575 calcium Substances 0.000 claims 4
- 229920001992 poloxamer 407 Polymers 0.000 claims 4
- 229940044476 poloxamer 407 Drugs 0.000 claims 4
- 229920001987 poloxamine Polymers 0.000 claims 4
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 3
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 3
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 3
- 239000000783 alginic acid Substances 0.000 claims 3
- 229960001126 alginic acid Drugs 0.000 claims 3
- 150000004781 alginic acids Chemical class 0.000 claims 3
- 229920002674 hyaluronan Polymers 0.000 claims 3
- 229960003160 hyaluronic acid Drugs 0.000 claims 3
- 210000003734 kidney Anatomy 0.000 claims 3
- 229910052749 magnesium Inorganic materials 0.000 claims 3
- 239000011777 magnesium Substances 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 239000011591 potassium Substances 0.000 claims 3
- 229910052700 potassium Inorganic materials 0.000 claims 3
- 235000010408 potassium alginate Nutrition 0.000 claims 3
- 239000000737 potassium alginate Substances 0.000 claims 3
- MZYRDLHIWXQJCQ-YZOKENDUSA-L potassium alginate Chemical compound [K+].[K+].O1[C@@H](C([O-])=O)[C@@H](OC)[C@H](O)[C@H](O)[C@@H]1O[C@@H]1[C@@H](C([O-])=O)O[C@@H](O)[C@@H](O)[C@H]1O MZYRDLHIWXQJCQ-YZOKENDUSA-L 0.000 claims 3
- 239000011734 sodium Substances 0.000 claims 3
- 229910052708 sodium Inorganic materials 0.000 claims 3
- 235000010413 sodium alginate Nutrition 0.000 claims 3
- 239000000661 sodium alginate Substances 0.000 claims 3
- 229940005550 sodium alginate Drugs 0.000 claims 3
- 229940124597 therapeutic agent Drugs 0.000 claims 3
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 claims 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 229920002517 Poloxamer 338 Polymers 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 229910052788 barium Inorganic materials 0.000 claims 2
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 claims 2
- 229920001400 block copolymer Polymers 0.000 claims 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 2
- 210000004185 liver Anatomy 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 229920001993 poloxamer 188 Polymers 0.000 claims 2
- 229940044519 poloxamer 188 Drugs 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- 210000002307 prostate Anatomy 0.000 claims 2
- 235000015424 sodium Nutrition 0.000 claims 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 102000011632 Caseins Human genes 0.000 claims 1
- 108010076119 Caseins Proteins 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 102000016942 Elastin Human genes 0.000 claims 1
- 108010014258 Elastin Proteins 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 108010049003 Fibrinogen Proteins 0.000 claims 1
- 102000008946 Fibrinogen Human genes 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 108010076876 Keratins Proteins 0.000 claims 1
- 102000011782 Keratins Human genes 0.000 claims 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 102000007327 Protamines Human genes 0.000 claims 1
- 108010007568 Protamines Proteins 0.000 claims 1
- 102000043322 Reelin Human genes 0.000 claims 1
- 108700038365 Reelin Proteins 0.000 claims 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- BCKXLBQYZLBQEK-KVVVOXFISA-M Sodium oleate Chemical compound [Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O BCKXLBQYZLBQEK-KVVVOXFISA-M 0.000 claims 1
- 229910052768 actinide Inorganic materials 0.000 claims 1
- 150000001255 actinides Chemical class 0.000 claims 1
- WNLRTRBMVRJNCN-UHFFFAOYSA-L adipate(2-) Chemical compound [O-]C(=O)CCCCC([O-])=O WNLRTRBMVRJNCN-UHFFFAOYSA-L 0.000 claims 1
- 229940050528 albumin Drugs 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 229940035676 analgesics Drugs 0.000 claims 1
- 229920006318 anionic polymer Polymers 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 229940124599 anti-inflammatory drug Drugs 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 229940124350 antibacterial drug Drugs 0.000 claims 1
- -1 antibacterial drugs Substances 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 229920005605 branched copolymer Polymers 0.000 claims 1
- 239000005018 casein Substances 0.000 claims 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims 1
- 235000021240 caseins Nutrition 0.000 claims 1
- 229920006317 cationic polymer Polymers 0.000 claims 1
- 229940044683 chemotherapy drug Drugs 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 230000009977 dual effect Effects 0.000 claims 1
- 239000000975 dye Substances 0.000 claims 1
- 229920002549 elastin Polymers 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 229940012952 fibrinogen Drugs 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- 229920000578 graft copolymer Polymers 0.000 claims 1
- 230000023597 hemostasis Effects 0.000 claims 1
- 229910052747 lanthanoid Inorganic materials 0.000 claims 1
- 150000002602 lanthanoids Chemical class 0.000 claims 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 1
- 229920000609 methyl cellulose Polymers 0.000 claims 1
- 239000001923 methylcellulose Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 claims 1
- 239000002907 paramagnetic material Substances 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 230000010412 perfusion Effects 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 229940048914 protamine Drugs 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 229920005604 random copolymer Polymers 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- BTURAGWYSMTVOW-UHFFFAOYSA-M sodium dodecanoate Chemical group [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 claims 1
- 229940082004 sodium laurate Drugs 0.000 claims 1
- FIWQZURFGYXCEO-UHFFFAOYSA-M sodium;decanoate Chemical compound [Na+].CCCCCCCCCC([O-])=O FIWQZURFGYXCEO-UHFFFAOYSA-M 0.000 claims 1
- 210000000952 spleen Anatomy 0.000 claims 1
- 229910052712 strontium Inorganic materials 0.000 claims 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 claims 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
- 229910052723 transition metal Inorganic materials 0.000 claims 1
- 150000003624 transition metals Chemical class 0.000 claims 1
- 210000004291 uterus Anatomy 0.000 claims 1
- 230000006459 vascular development Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87406206P | 2006-12-11 | 2006-12-11 | |
| US89399307P | 2007-03-09 | 2007-03-09 | |
| PCT/US2007/087079 WO2008073938A2 (en) | 2006-12-11 | 2007-12-11 | Perfusive organ hemostasis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014048739A Division JP5931943B2 (ja) | 2006-12-11 | 2014-03-12 | 灌流臓器止血法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010512230A JP2010512230A (ja) | 2010-04-22 |
| JP2010512230A5 true JP2010512230A5 (enExample) | 2011-02-10 |
Family
ID=39512452
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541532A Pending JP2010512230A (ja) | 2006-12-11 | 2007-12-11 | 灌流臓器止血法 |
| JP2014048739A Expired - Fee Related JP5931943B2 (ja) | 2006-12-11 | 2014-03-12 | 灌流臓器止血法 |
| JP2016089234A Pending JP2016135365A (ja) | 2006-12-11 | 2016-04-27 | 灌流臓器止血法 |
| JP2017187859A Pending JP2018000996A (ja) | 2006-12-11 | 2017-09-28 | 灌流臓器止血法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014048739A Expired - Fee Related JP5931943B2 (ja) | 2006-12-11 | 2014-03-12 | 灌流臓器止血法 |
| JP2016089234A Pending JP2016135365A (ja) | 2006-12-11 | 2016-04-27 | 灌流臓器止血法 |
| JP2017187859A Pending JP2018000996A (ja) | 2006-12-11 | 2017-09-28 | 灌流臓器止血法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US20080181952A1 (enExample) |
| EP (1) | EP2094169A4 (enExample) |
| JP (4) | JP2010512230A (enExample) |
| CN (2) | CN105251035A (enExample) |
| WO (1) | WO2008073938A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2866133B2 (ja) | 1989-07-25 | 1999-03-08 | 株式会社リコー | 液体噴射記録装置及び方法 |
| JP2989243B2 (ja) | 1990-10-16 | 1999-12-13 | 株式会社リコー | 液体噴射記録方法及び装置 |
| JP2989242B2 (ja) | 1990-10-16 | 1999-12-13 | 株式会社リコー | 液体噴射記録方法及び装置 |
| JP2957676B2 (ja) | 1990-10-16 | 1999-10-06 | 株式会社リコー | 液体噴射記録装置及び方法 |
| WO2008018892A2 (en) * | 2005-12-22 | 2008-02-14 | Pluromed, Inc. | Methods and kits for treating lacerations and puncture wounds using inverse thermosensitive polymers |
| US8197499B2 (en) | 2006-06-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
| EP2034906A4 (en) | 2006-06-21 | 2010-07-28 | Univ Leland Stanford Junior | COMPOSITIONS AND METHODS FOR CONNECTING NON-ASSOCIATED LUMENS |
| US8608760B2 (en) * | 2006-06-21 | 2013-12-17 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for joining non-conjoined lumens |
| KR101428122B1 (ko) | 2006-12-15 | 2014-08-07 | 라이프본드 엘티디. | 젤라틴-트랜스글루타미나아제 지혈 드레싱 및 실란트 |
| US20080208163A1 (en) * | 2007-02-22 | 2008-08-28 | Pluromed, Inc. | Use of Reverse Thermosensitive Polymers to Control Biological Fluid Flow Following a Medical Procedure |
| BRPI0820785A2 (pt) * | 2007-12-20 | 2015-06-16 | Tautona Group L P | Composições e métodos para unir lúmens não unidos |
| US8394795B2 (en) * | 2008-02-29 | 2013-03-12 | Array Biopharma Inc. | Pyrazole [3, 4-B] pyridine Raf inhibitors |
| CN106037857A (zh) * | 2008-02-29 | 2016-10-26 | 普拉罗美德公司 | 通过加热热敏聚合物进行的局部栓塞 |
| BRPI0912482A2 (pt) | 2008-05-14 | 2020-08-18 | Otonomy, Inc | composições de corticosteróide de liberação controlada e métodos para o tratamento de distúrbios auriculares |
| JP5450612B2 (ja) | 2008-06-18 | 2014-03-26 | ライフボンド リミテッド | 改良された架橋組成物 |
| US8318817B2 (en) | 2008-07-21 | 2012-11-27 | Otonomy, Inc. | Controlled release antimicrobial compositions and methods for the treatment of otic disorders |
| US8563037B2 (en) * | 2009-02-06 | 2013-10-22 | Tautona Group, L.P. | Compositions and methods for joining non-conjoined lumens |
| EP2480204B1 (en) * | 2009-09-22 | 2013-11-06 | Vlife Sciences Technologies Pvt Ltd. | Topical formulation for diabetic foot ulcers |
| EP2490722A4 (en) * | 2009-10-21 | 2014-03-05 | Otonomy Inc | MODULATION OF THE TEMPERATURE OF GELIFICATION OF FORMULATIONS CONTAINING POLOXAMERS |
| BR112012015029A2 (pt) | 2009-12-22 | 2017-06-27 | Lifebond Ltd | matriz reticulada, método para controlar a formação de uma matriz, método ou matriz, método para vedar um tecido contra vazamento de um fluído corporal, agente hemostático ou vedante cirúrgico, composição para vedar um ferimento, uso da composição, composição para um veículo para entrega localizada de fármaco, composição para engenharia de tecido, e método para modificar uma composição |
| EP2600910B1 (en) | 2010-08-05 | 2016-01-20 | Lifebond Ltd | Dry composition wound dressings and adhesives |
| US9060749B2 (en) | 2011-08-12 | 2015-06-23 | Boston Scientific Scimed, Inc. | Methods, compositions and kits for performing anastomosis procedures in conjunction with a radical prostatectomy procedure |
| US9433699B2 (en) | 2011-11-21 | 2016-09-06 | Innotherapy Inc. | Hydrogel comprising catechol group-coupled chitosan or polyamine and poloxamer comprising thiol group coupled to end thereof, preparation method thereof, and hemostat using same |
| DE102013211316A1 (de) * | 2013-06-17 | 2014-12-18 | Aesculap Ag | Hämostyptikum |
| US9486405B2 (en) | 2013-08-27 | 2016-11-08 | Otonomy, Inc. | Methods for the treatment of pediatric otic disorders |
| ITMI20131924A1 (it) * | 2013-11-20 | 2015-05-21 | Cosmo Technologies Ltd | Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica |
| ITMI20131927A1 (it) * | 2013-11-20 | 2015-05-21 | Cosmo Technologies Ltd | Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection. emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica |
| JP6562902B2 (ja) * | 2014-03-28 | 2019-08-21 | テルモ株式会社 | 生体血管内血液置換用液体、生体血管内血液置換用液体製剤およびプレフィルドシリンジ |
| AR102147A1 (es) * | 2014-10-01 | 2017-02-08 | Als Mountain Llc | Composición farmacéutica que comprende aspirina, metformina y serotonina con agente tensioactivo no iónico |
| US20170274189A1 (en) * | 2016-03-24 | 2017-09-28 | Ethicon, Inc. | Single lumen balloon delivery catheter with lumen bypass at balloon |
| CN108714243A (zh) * | 2017-06-08 | 2018-10-30 | 重庆大学 | 用于脑出血术后止血的植入剂及其制备方法 |
| WO2019163012A1 (ja) * | 2018-02-21 | 2019-08-29 | 国立大学法人信州大学 | 液体塞栓剤組成物 |
| EP4233914A3 (en) | 2018-03-16 | 2023-10-18 | Critical Innovations, LLC | Systems and methods relating to medical applications of synthetic polymer formulations |
| US11998654B2 (en) | 2018-07-12 | 2024-06-04 | Bard Shannon Limited | Securing implants and medical devices |
| CN112138204A (zh) * | 2019-06-26 | 2020-12-29 | 广东博与再生医学有限公司 | 骨止血材料 |
| JP7546265B2 (ja) * | 2020-05-22 | 2024-09-06 | ウェトラブホールディング株式会社 | 生体組織用二液型バインダーおよび生体組織用二液型充填材 |
| CN111632189B (zh) * | 2020-05-27 | 2021-12-14 | 深圳先进技术研究院 | 基于海洋源明胶的可注射水凝胶止血剂及应用和应用方法 |
| US12410293B2 (en) | 2022-11-07 | 2025-09-09 | Critical Innovations Llc | Systems and methods relating to medical applications of inverse thermosensitive polymer foam formulations |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US3889685A (en) * | 1973-11-02 | 1975-06-17 | Cutter Lab | Tubular unit with vessel engaging cuff structure |
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-
2007
- 2007-12-11 US US11/954,109 patent/US20080181952A1/en not_active Abandoned
- 2007-12-11 JP JP2009541532A patent/JP2010512230A/ja active Pending
- 2007-12-11 WO PCT/US2007/087079 patent/WO2008073938A2/en not_active Ceased
- 2007-12-11 CN CN201510386368.0A patent/CN105251035A/zh active Pending
- 2007-12-11 CN CN200780051223A patent/CN101677822A/zh active Pending
- 2007-12-11 EP EP07865497.7A patent/EP2094169A4/en not_active Withdrawn
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2014
- 2014-03-12 JP JP2014048739A patent/JP5931943B2/ja not_active Expired - Fee Related
- 2014-03-25 US US14/225,299 patent/US20140205542A1/en not_active Abandoned
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2016
- 2016-03-18 US US15/074,432 patent/US20170043050A1/en not_active Abandoned
- 2016-04-27 JP JP2016089234A patent/JP2016135365A/ja active Pending
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2017
- 2017-06-13 US US15/621,704 patent/US20180117211A1/en not_active Abandoned
- 2017-09-28 JP JP2017187859A patent/JP2018000996A/ja active Pending
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