JP2013545734A5 - - Google Patents
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- JP2013545734A5 JP2013545734A5 JP2013536812A JP2013536812A JP2013545734A5 JP 2013545734 A5 JP2013545734 A5 JP 2013545734A5 JP 2013536812 A JP2013536812 A JP 2013536812A JP 2013536812 A JP2013536812 A JP 2013536812A JP 2013545734 A5 JP2013545734 A5 JP 2013545734A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40712810P | 2010-10-27 | 2010-10-27 | |
| US61/407,128 | 2010-10-27 | ||
| PCT/US2011/058025 WO2012058393A2 (en) | 2010-10-27 | 2011-10-27 | Dkk1 antibodies and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016175266A Division JP6353500B2 (ja) | 2010-10-27 | 2016-09-08 | Dkk1抗体およびその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013545734A JP2013545734A (ja) | 2013-12-26 |
| JP2013545734A5 true JP2013545734A5 (enExample) | 2014-08-21 |
| JP6066912B2 JP6066912B2 (ja) | 2017-01-25 |
Family
ID=44910313
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013536812A Active JP6066912B2 (ja) | 2010-10-27 | 2011-10-27 | Dkk1抗体およびその使用方法 |
| JP2016175266A Active JP6353500B2 (ja) | 2010-10-27 | 2016-09-08 | Dkk1抗体およびその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016175266A Active JP6353500B2 (ja) | 2010-10-27 | 2016-09-08 | Dkk1抗体およびその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US9879072B2 (enExample) |
| EP (3) | EP3838922A1 (enExample) |
| JP (2) | JP6066912B2 (enExample) |
| AR (2) | AR083740A1 (enExample) |
| AU (3) | AU2011319843C1 (enExample) |
| CA (2) | CA2815181C (enExample) |
| ES (1) | ES2863626T3 (enExample) |
| MX (3) | MX382826B (enExample) |
| TW (2) | TWI636993B (enExample) |
| WO (1) | WO2012058393A2 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2639020T3 (es) | 1998-11-27 | 2017-10-25 | Ucb Pharma S.A. | Composiciones y métodos para incrementar la mineralización de la substancia ósea |
| US7592429B2 (en) | 2005-05-03 | 2009-09-22 | Ucb Sa | Sclerostin-binding antibody |
| US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
| CL2008002775A1 (es) | 2007-09-17 | 2008-11-07 | Amgen Inc | Uso de un agente de unión a esclerostina para inhibir la resorción ósea. |
| EP2331136B1 (en) | 2008-09-26 | 2018-01-10 | OncoMed Pharmaceuticals, Inc. | Frizzled-binding agents and uses thereof |
| TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Wnt拮抗劑及治療和篩選方法 |
| CN102971337B (zh) | 2010-04-01 | 2016-09-21 | 昂考梅德药品有限公司 | 卷曲蛋白结合药剂及其应用 |
| SMT202000095T1 (it) | 2010-05-14 | 2020-03-13 | Amgen Inc | Formulazioni di anticorpi anti-sclerostina ad alta concentrazione |
| US11167011B2 (en) | 2010-06-07 | 2021-11-09 | Enzo Biochem, Inc. | Methods for treating bone loss using sclerostin peptides |
| US9493541B2 (en) * | 2010-06-07 | 2016-11-15 | Joshua Rabbani | Antibodies specific for sulfated sclerostin |
| US9403882B2 (en) | 2010-06-07 | 2016-08-02 | Joshua Rabbani | Sulfation of Wnt pathway proteins |
| US9617323B2 (en) | 2010-06-07 | 2017-04-11 | Joshua Rabbani | Sulfonated sclerostin, antibodies, epitopes and methods for identification and use therefor |
| EP3838922A1 (en) * | 2010-10-27 | 2021-06-23 | Amgen Inc. | Dkk1 antibodies and methods of use |
| JP2014509588A (ja) | 2011-03-01 | 2014-04-21 | アムジエン・インコーポレーテツド | 二特異性結合剤 |
| US9145457B2 (en) | 2011-03-25 | 2015-09-29 | Amgen Inc. | Sclerostin antibody crystals and formulations thereof |
| ES2667554T3 (es) | 2011-08-04 | 2018-05-11 | Amgen Inc. | Método para el tratamiento de los defectos de espacio óseo |
| KR20190120401A (ko) | 2011-12-28 | 2019-10-23 | 암젠 인크 | 항스클레로스틴 항체의 이용을 통한 치조골 소실의 치료 방법 |
| WO2013152860A2 (en) * | 2012-04-11 | 2013-10-17 | Dutalys Gmbh | Improved antibody light chains |
| JP6770312B2 (ja) | 2012-07-05 | 2020-10-14 | ユセベ ファルマ ソシエテ アノニム | 骨疾患の治療 |
| JP2015536933A (ja) | 2012-10-23 | 2015-12-24 | オンコメッド ファーマシューティカルズ インコーポレイテッド | Wnt経路結合剤を用いて神経内分泌腫瘍を処置する方法 |
| UY35148A (es) * | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| CN105073195A (zh) * | 2013-02-04 | 2015-11-18 | 昂科梅德制药有限公司 | 使用Wnt途径抑制剂进行治疗的方法及对该治疗的监测 |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| MA41142A (fr) | 2014-12-12 | 2017-10-17 | Amgen Inc | Anticorps anti-sclérostine et utilisation de ceux-ci pour traiter des affections osseuses en tant qu'élements du protocole de traitement |
| WO2017127706A1 (en) * | 2016-01-22 | 2017-07-27 | Yale University | Compositions and methods for inhibiting dkk-1 |
| GB201604124D0 (en) | 2016-03-10 | 2016-04-27 | Ucb Biopharma Sprl | Pharmaceutical formulation |
| US10961305B2 (en) | 2016-12-21 | 2021-03-30 | Mereo Biopharma 3 Limited | Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta |
| WO2018139623A1 (en) | 2017-01-30 | 2018-08-02 | Chugai Seiyaku Kabushiki Kaisha | Anti-sclerostin antibodies and methods of use |
| KR102956517B1 (ko) | 2017-10-04 | 2026-04-23 | 암젠 인크 | 트랜스타이레틴 면역글로불린 융합 |
| EP4169576A1 (en) * | 2018-03-23 | 2023-04-26 | University of Massachusetts | Gene therapeutics for treating bone disorders |
| EP3774879B1 (en) | 2018-03-30 | 2026-01-28 | Amgen Inc. | C-terminal antibody variants |
| EP3787645A4 (en) * | 2018-05-02 | 2022-06-01 | Ortheus, Inc. | SYSTEMS AND METHODS FOR LOCAL MODULATION OF WNT SIGNALING |
| JP7840511B2 (ja) | 2019-02-01 | 2026-04-06 | 石▲薬▼集▲団▼巨石生物制▲薬▼有限公司 | 抗クローディン18抗体及びそれらの使用の方法 |
| MX2021010441A (es) | 2019-03-01 | 2021-09-21 | Allogene Therapeutics Inc | Receptores antigenicos quimericos y agentes de union dirigidos a dll3. |
| CN112121147B (zh) * | 2019-06-24 | 2023-07-04 | 中国人民解放军海军特色医学中心 | 多肽在治疗或预防骨髓瘤药物中的应用、多肽、核酸、药物及重组表达载体 |
| CN112180094A (zh) * | 2019-07-04 | 2021-01-05 | 上海东慈生物科技有限公司 | Dkk1抑制剂在预防和/或治疗肿瘤恶病质与糖尿病伴随疾病中的应用 |
| TR201920272A1 (tr) * | 2019-12-15 | 2021-06-21 | Uludamar Altay | Dental i̇mplantlar, greft materyalleri̇ ve prf i̇le osseoi̇ntegrasyonun artirilmasi i̇çi̇n bi̇r terapöti̇k kompozi̇syon ve bunun lokal kullanim yöntemleri̇ |
| EP4255451A4 (en) * | 2020-12-03 | 2025-01-01 | The Board Of Regents Of The University Of Texas System | Methods for identifying lilrb-blocking antibodies |
| CN116963747A (zh) * | 2020-12-03 | 2023-10-27 | 德克萨斯大学体系董事会 | 用于鉴定lilrb阻断抗体的方法 |
| CA3217029A1 (en) | 2021-05-30 | 2022-12-08 | Biolojic Design Ltd. | Engineered dual binding antibodies and uses thereof |
| WO2023143444A1 (zh) * | 2022-01-28 | 2023-08-03 | 上海君实生物医药科技股份有限公司 | 抗dkk1抗体、其药物组合物及用途 |
| JP2026524087A (ja) * | 2023-06-07 | 2026-07-17 | チュン アン ユニバーシティ インダストリ アカデミック コーポレーション ファウンデーション | スクレロスチン阻害剤を有効成分として含む糖尿病性眼疾患の予防又は治療用医薬組成物 |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4263428A (en) | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| EP0088046B1 (de) | 1982-02-17 | 1987-12-09 | Ciba-Geigy Ag | Lipide in wässriger Phase |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
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| EP0143949B1 (en) | 1983-11-01 | 1988-10-12 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Pharmaceutical composition containing urokinase |
| US4740461A (en) | 1983-12-27 | 1988-04-26 | Genetics Institute, Inc. | Vectors and methods for transformation of eucaryotic cells |
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| CN101641373B (zh) * | 2007-02-08 | 2015-02-11 | 默沙东公司 | Dkk-1的特异性抗体 |
| AR068767A1 (es) | 2007-10-12 | 2009-12-02 | Novartis Ag | Anticuerpos contra esclerostina, composiciones y metodos de uso de estos anticuerpos para tratar un trastorno patologico mediado por esclerostina |
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| CA2737667A1 (en) * | 2008-09-19 | 2010-03-25 | Medimmune, Llc | Targeted binding agents directed to cd105 and uses thereof |
| AR076668A1 (es) * | 2009-05-12 | 2011-06-29 | Pfizer | Anticuerpos especificos para dkk-1 y sus usos |
| EP3838922A1 (en) * | 2010-10-27 | 2021-06-23 | Amgen Inc. | Dkk1 antibodies and methods of use |
| JP2014509588A (ja) * | 2011-03-01 | 2014-04-21 | アムジエン・インコーポレーテツド | 二特異性結合剤 |
| ES2667554T3 (es) * | 2011-08-04 | 2018-05-11 | Amgen Inc. | Método para el tratamiento de los defectos de espacio óseo |
| KR20190120401A (ko) * | 2011-12-28 | 2019-10-23 | 암젠 인크 | 항스클레로스틴 항체의 이용을 통한 치조골 소실의 치료 방법 |
| WO2013180295A1 (ja) | 2012-06-01 | 2013-12-05 | 日本電信電話株式会社 | パケット転送処理方法およびパケット転送処理装置 |
| UY35148A (es) * | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
| US9300829B2 (en) | 2014-04-04 | 2016-03-29 | Canon Kabushiki Kaisha | Image reading apparatus and correction method thereof |
-
2011
- 2011-10-27 EP EP20213270.0A patent/EP3838922A1/en active Pending
- 2011-10-27 US US13/878,619 patent/US9879072B2/en active Active
- 2011-10-27 CA CA2815181A patent/CA2815181C/en active Active
- 2011-10-27 AR ARP110103984A patent/AR083740A1/es active IP Right Grant
- 2011-10-27 AU AU2011319843A patent/AU2011319843C1/en active Active
- 2011-10-27 CA CA3085710A patent/CA3085710A1/en active Pending
- 2011-10-27 MX MX2017013617A patent/MX382826B/es unknown
- 2011-10-27 EP EP11779531.0A patent/EP2632951B1/en active Active
- 2011-10-27 EP EP17169408.6A patent/EP3219725B1/en active Active
- 2011-10-27 TW TW100139221A patent/TWI636993B/zh active
- 2011-10-27 WO PCT/US2011/058025 patent/WO2012058393A2/en not_active Ceased
- 2011-10-27 MX MX2013004726A patent/MX354481B/es active IP Right Grant
- 2011-10-27 JP JP2013536812A patent/JP6066912B2/ja active Active
- 2011-10-27 ES ES17169408T patent/ES2863626T3/es active Active
- 2011-10-27 TW TW105125647A patent/TWI636994B/zh active
-
2013
- 2013-04-26 MX MX2021001494A patent/MX2021001494A/es unknown
-
2016
- 2016-06-03 AU AU2016203722A patent/AU2016203722A1/en not_active Abandoned
- 2016-09-08 JP JP2016175266A patent/JP6353500B2/ja active Active
-
2017
- 2017-12-13 US US15/841,065 patent/US10800839B2/en active Active
-
2018
- 2018-02-23 AU AU2018201333A patent/AU2018201333B2/en active Active
-
2020
- 2020-02-10 AR ARP200100356A patent/AR118047A2/es unknown
- 2020-09-09 US US17/015,212 patent/US12297260B2/en active Active
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