JP2013545584A5 - - Google Patents
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- JP2013545584A5 JP2013545584A5 JP2013544705A JP2013544705A JP2013545584A5 JP 2013545584 A5 JP2013545584 A5 JP 2013545584A5 JP 2013544705 A JP2013544705 A JP 2013544705A JP 2013544705 A JP2013544705 A JP 2013544705A JP 2013545584 A5 JP2013545584 A5 JP 2013545584A5
- Authority
- JP
- Japan
- Prior art keywords
- pdgf
- composition according
- scaffolding material
- bone scaffolding
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000203 mixture Substances 0.000 claims 22
- 210000000988 bone and bone Anatomy 0.000 claims 14
- 239000000463 material Substances 0.000 claims 14
- 108010081589 Becaplermin Proteins 0.000 claims 6
- 108010038512 Platelet-Derived Growth Factor Proteins 0.000 claims 6
- 102000010780 Platelet-Derived Growth Factor Human genes 0.000 claims 6
- 230000004927 fusion Effects 0.000 claims 5
- 239000011159 matrix material Substances 0.000 claims 5
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 3
- 102000008186 Collagen Human genes 0.000 claims 2
- 108010035532 Collagen Proteins 0.000 claims 2
- 239000011230 binding agent Substances 0.000 claims 2
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 2
- 239000001506 calcium phosphate Substances 0.000 claims 2
- 235000011010 calcium phosphates Nutrition 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- 210000002805 bone matrix Anatomy 0.000 claims 1
- 230000012292 cell migration Effects 0.000 claims 1
- 238000002513 implantation Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 108010017843 platelet-derived growth factor A Proteins 0.000 claims 1
- 108010000685 platelet-derived growth factor AB Proteins 0.000 claims 1
- 108010017992 platelet-derived growth factor C Proteins 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42264910P | 2010-12-13 | 2010-12-13 | |
| US61/422,649 | 2010-12-13 | ||
| PCT/US2011/064698 WO2012082773A1 (en) | 2010-12-13 | 2011-12-13 | Compositions and methods for spine fusion procedures |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016211737A Division JP2017018710A (ja) | 2010-12-13 | 2016-10-28 | 脊椎固定術用の組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013545584A JP2013545584A (ja) | 2013-12-26 |
| JP2013545584A5 true JP2013545584A5 (cg-RX-API-DMAC7.html) | 2015-02-05 |
| JP6116484B2 JP6116484B2 (ja) | 2017-04-19 |
Family
ID=46245079
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013544705A Expired - Fee Related JP6116484B2 (ja) | 2010-12-13 | 2011-12-13 | 脊椎固定術用の組成物および方法 |
| JP2016211737A Pending JP2017018710A (ja) | 2010-12-13 | 2016-10-28 | 脊椎固定術用の組成物および方法 |
| JP2018139921A Pending JP2018161541A (ja) | 2010-12-13 | 2018-07-26 | 脊椎固定術用の組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016211737A Pending JP2017018710A (ja) | 2010-12-13 | 2016-10-28 | 脊椎固定術用の組成物および方法 |
| JP2018139921A Pending JP2018161541A (ja) | 2010-12-13 | 2018-07-26 | 脊椎固定術用の組成物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20140308332A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2651319A4 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6116484B2 (cg-RX-API-DMAC7.html) |
| KR (3) | KR20200055149A (cg-RX-API-DMAC7.html) |
| CN (2) | CN103491888A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011343995A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013014686A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2819258C (cg-RX-API-DMAC7.html) |
| MX (1) | MX362405B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012082773A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2654796A1 (en) | 2010-12-21 | 2013-10-30 | Koninklijke Philips N.V. | Agents for clearing biomolecules from circulation |
| WO2016043955A1 (en) * | 2014-08-28 | 2016-03-24 | Bioventus, Llc | Improved osteoinductive substrates and methods of making the same |
| CN107106492B (zh) | 2014-10-14 | 2022-07-05 | 塞缪尔·林奇 | 用于治疗伤口的组合物 |
| JP2018500135A (ja) | 2014-12-29 | 2018-01-11 | バイオヴェンタス・エルエルシー | 骨修復における骨誘導分子の改善された送達システム及び方法 |
| WO2017019959A1 (en) * | 2015-07-30 | 2017-02-02 | Clarion Research Group | Formulations and methods for recovery from spinal surgery |
| EP3368094B1 (en) | 2015-10-30 | 2021-03-10 | Bioventus LLC | Matrix for enhanced delivery of osteoinductive molecules in bone repair |
| US12318475B2 (en) | 2016-03-14 | 2025-06-03 | The University Of Chicago | Injectable pastes based on oppositely charged polymer/calcium phosphate nanoparticles |
| JP2019518550A (ja) | 2016-06-10 | 2019-07-04 | バイオヴェンタス・エルエルシー | 多孔質金属構造物でのタンパク質送達 |
| WO2019014576A1 (en) * | 2017-07-14 | 2019-01-17 | The University Of Chicago | LYOPHILIZED FORMULATIONS COMPRISING NANOPARTICLES AND METHODS OF LYOPHILIZATION |
| JP2022525168A (ja) * | 2019-03-14 | 2022-05-11 | バイオミメティック セラピューティクス，リミテッド ライアビリティ カンパニー | 骨癒合を増強するための血小板由来増殖因子製剤 |
| EP3795185A1 (en) * | 2019-09-23 | 2021-03-24 | Kuros Biosurgery AG | Bone graft material for use in a spinal fusion method |
| CN111481741A (zh) * | 2020-04-15 | 2020-08-04 | 花沐医疗科技(上海)有限公司 | 复合可吸收自锁定颈椎融合器及其制备方法 |
| KR102667977B1 (ko) | 2020-05-08 | 2024-05-22 | 주식회사 에이치엘클레무브 | 차량용 레이더 장치 및 제어방법 |
| WO2025042830A1 (en) | 2023-08-18 | 2025-02-27 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor bone graft putty formulation |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010037091A1 (en) * | 1999-12-29 | 2001-11-01 | Wironen John F. | System for reconstituting pastes and methods of using same |
| DE60137073D1 (de) * | 2000-10-24 | 2009-01-29 | Warsaw Orthopedic Inc | Vorrichtungen für die spinalfusion |
| AU2004212942A1 (en) * | 2003-02-14 | 2004-09-02 | Depuy Spine, Inc. | In-situ formed intervertebral fusion device |
| US20040193270A1 (en) * | 2003-03-31 | 2004-09-30 | Depuyacromed, Inc. | Implantable bone graft |
| CN1640368A (zh) * | 2004-01-06 | 2005-07-20 | 宋跃明 | 椎间融合装置 |
| US7901650B2 (en) * | 2005-06-22 | 2011-03-08 | Skeletal Kinectics, LLC | Porous beta-tricalcium phosphate and methods for producing the same |
| EP2431060B1 (en) * | 2005-11-17 | 2020-04-08 | BioMimetic Therapeutics, LLC | Maxillofacial bone augmentation using RHPDGF-BB and a biocompatible matrix |
| JP5068269B2 (ja) * | 2005-12-14 | 2012-11-07 | シル テクノロジー ゲーエムベーハー | 骨再生のための成形可能な生体材料 |
| WO2008151193A1 (en) * | 2007-06-04 | 2008-12-11 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating the vertebral column |
| US9161967B2 (en) * | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| AU2007333425B2 (en) * | 2006-11-03 | 2014-03-27 | Stryker Corporation | Compositions and methods for arthrodetic procedures |
| US8241357B2 (en) * | 2007-04-25 | 2012-08-14 | Jmea Corporation | Prosthesis with a selectively applied bone growth promoting agent |
| US20090048675A1 (en) * | 2007-04-25 | 2009-02-19 | Bhatnagar Mohit K | Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent |
| CN101121753B (zh) * | 2007-06-06 | 2011-11-16 | 天津林达生物科技有限公司 | 对多种皮肤细胞修复具持续作用的人血清白蛋白重组融合蛋白 |
| CA2698017C (en) * | 2007-08-29 | 2016-12-13 | Etex Corporation | Bone cement mixing and delivery system and methods of use thereof |
| CN105854074B (zh) * | 2008-02-07 | 2019-10-15 | 生物模拟治疗有限责任公司 | 用于牵引成骨术的组合物和方法 |
| JP2012519556A (ja) * | 2009-03-05 | 2012-08-30 | バイオミメティック セラピューティクス， インコーポレイテッド | 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 |
-
2011
- 2011-12-13 US US13/992,033 patent/US20140308332A1/en not_active Abandoned
- 2011-12-13 AU AU2011343995A patent/AU2011343995A1/en not_active Abandoned
- 2011-12-13 MX MX2013006697A patent/MX362405B/es active IP Right Grant
- 2011-12-13 WO PCT/US2011/064698 patent/WO2012082773A1/en not_active Ceased
- 2011-12-13 BR BR112013014686A patent/BR112013014686A2/pt not_active IP Right Cessation
- 2011-12-13 JP JP2013544705A patent/JP6116484B2/ja not_active Expired - Fee Related
- 2011-12-13 KR KR1020207013423A patent/KR20200055149A/ko not_active Ceased
- 2011-12-13 CN CN201180067451.1A patent/CN103491888A/zh active Pending
- 2011-12-13 CN CN201810399549.0A patent/CN108498873A/zh active Pending
- 2011-12-13 EP EP11848160.5A patent/EP2651319A4/en not_active Withdrawn
- 2011-12-13 KR KR1020187031242A patent/KR20180121674A/ko not_active Ceased
- 2011-12-13 KR KR1020137015102A patent/KR20140038348A/ko not_active Ceased
- 2011-12-13 CA CA2819258A patent/CA2819258C/en active Active
-
2016
- 2016-10-28 JP JP2016211737A patent/JP2017018710A/ja active Pending
-
2018
- 2018-05-08 US US15/973,903 patent/US20190365946A1/en not_active Abandoned
- 2018-07-26 JP JP2018139921A patent/JP2018161541A/ja active Pending
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