CA2819258C - Compositions and methods for spine fusion procedures - Google Patents
Compositions and methods for spine fusion procedures Download PDFInfo
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- CA2819258C CA2819258C CA2819258A CA2819258A CA2819258C CA 2819258 C CA2819258 C CA 2819258C CA 2819258 A CA2819258 A CA 2819258A CA 2819258 A CA2819258 A CA 2819258A CA 2819258 C CA2819258 C CA 2819258C
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- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- YIGWVOWKHUSYER-UHFFFAOYSA-F tetracalcium;hydrogen phosphate;diphosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].OP([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O YIGWVOWKHUSYER-UHFFFAOYSA-F 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000003232 water-soluble binding agent Substances 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
- A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Materials Engineering (AREA)
- Urology & Nephrology (AREA)
- Botany (AREA)
- Composite Materials (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US42264910P | 2010-12-13 | 2010-12-13 | |
| US61/422,649 | 2010-12-13 | ||
| PCT/US2011/064698 WO2012082773A1 (en) | 2010-12-13 | 2011-12-13 | Compositions and methods for spine fusion procedures |
Publications (2)
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| CA2819258A1 CA2819258A1 (en) | 2012-06-21 |
| CA2819258C true CA2819258C (en) | 2020-03-10 |
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| CA2819258A Active CA2819258C (en) | 2010-12-13 | 2011-12-13 | Compositions and methods for spine fusion procedures |
Country Status (10)
| Country | Link |
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| US (2) | US20140308332A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2651319A4 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6116484B2 (cg-RX-API-DMAC7.html) |
| KR (3) | KR20200055149A (cg-RX-API-DMAC7.html) |
| CN (2) | CN103491888A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011343995A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013014686A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2819258C (cg-RX-API-DMAC7.html) |
| MX (1) | MX362405B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012082773A1 (cg-RX-API-DMAC7.html) |
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| EP2654796A1 (en) | 2010-12-21 | 2013-10-30 | Koninklijke Philips N.V. | Agents for clearing biomolecules from circulation |
| WO2016043955A1 (en) * | 2014-08-28 | 2016-03-24 | Bioventus, Llc | Improved osteoinductive substrates and methods of making the same |
| CN107106492B (zh) | 2014-10-14 | 2022-07-05 | 塞缪尔·林奇 | 用于治疗伤口的组合物 |
| JP2018500135A (ja) | 2014-12-29 | 2018-01-11 | バイオヴェンタス・エルエルシー | 骨修復における骨誘導分子の改善された送達システム及び方法 |
| WO2017019959A1 (en) * | 2015-07-30 | 2017-02-02 | Clarion Research Group | Formulations and methods for recovery from spinal surgery |
| EP3368094B1 (en) | 2015-10-30 | 2021-03-10 | Bioventus LLC | Matrix for enhanced delivery of osteoinductive molecules in bone repair |
| US12318475B2 (en) | 2016-03-14 | 2025-06-03 | The University Of Chicago | Injectable pastes based on oppositely charged polymer/calcium phosphate nanoparticles |
| JP2019518550A (ja) | 2016-06-10 | 2019-07-04 | バイオヴェンタス・エルエルシー | 多孔質金属構造物でのタンパク質送達 |
| WO2019014576A1 (en) * | 2017-07-14 | 2019-01-17 | The University Of Chicago | LYOPHILIZED FORMULATIONS COMPRISING NANOPARTICLES AND METHODS OF LYOPHILIZATION |
| JP2022525168A (ja) * | 2019-03-14 | 2022-05-11 | バイオミメティック セラピューティクス，リミテッド ライアビリティ カンパニー | 骨癒合を増強するための血小板由来増殖因子製剤 |
| EP3795185A1 (en) * | 2019-09-23 | 2021-03-24 | Kuros Biosurgery AG | Bone graft material for use in a spinal fusion method |
| CN111481741A (zh) * | 2020-04-15 | 2020-08-04 | 花沐医疗科技(上海)有限公司 | 复合可吸收自锁定颈椎融合器及其制备方法 |
| KR102667977B1 (ko) | 2020-05-08 | 2024-05-22 | 주식회사 에이치엘클레무브 | 차량용 레이더 장치 및 제어방법 |
| WO2025042830A1 (en) | 2023-08-18 | 2025-02-27 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor bone graft putty formulation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010037091A1 (en) * | 1999-12-29 | 2001-11-01 | Wironen John F. | System for reconstituting pastes and methods of using same |
| DE60137073D1 (de) * | 2000-10-24 | 2009-01-29 | Warsaw Orthopedic Inc | Vorrichtungen für die spinalfusion |
| AU2004212942A1 (en) * | 2003-02-14 | 2004-09-02 | Depuy Spine, Inc. | In-situ formed intervertebral fusion device |
| US20040193270A1 (en) * | 2003-03-31 | 2004-09-30 | Depuyacromed, Inc. | Implantable bone graft |
| CN1640368A (zh) * | 2004-01-06 | 2005-07-20 | 宋跃明 | 椎间融合装置 |
| US7901650B2 (en) * | 2005-06-22 | 2011-03-08 | Skeletal Kinectics, LLC | Porous beta-tricalcium phosphate and methods for producing the same |
| EP2431060B1 (en) * | 2005-11-17 | 2020-04-08 | BioMimetic Therapeutics, LLC | Maxillofacial bone augmentation using RHPDGF-BB and a biocompatible matrix |
| JP5068269B2 (ja) * | 2005-12-14 | 2012-11-07 | シル テクノロジー ゲーエムベーハー | 骨再生のための成形可能な生体材料 |
| WO2008151193A1 (en) * | 2007-06-04 | 2008-12-11 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating the vertebral column |
| US9161967B2 (en) * | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| AU2007333425B2 (en) * | 2006-11-03 | 2014-03-27 | Stryker Corporation | Compositions and methods for arthrodetic procedures |
| US8241357B2 (en) * | 2007-04-25 | 2012-08-14 | Jmea Corporation | Prosthesis with a selectively applied bone growth promoting agent |
| US20090048675A1 (en) * | 2007-04-25 | 2009-02-19 | Bhatnagar Mohit K | Spinal Fusion Implants with Selectively Applied Bone Growth Promoting Agent |
| CN101121753B (zh) * | 2007-06-06 | 2011-11-16 | 天津林达生物科技有限公司 | 对多种皮肤细胞修复具持续作用的人血清白蛋白重组融合蛋白 |
| CA2698017C (en) * | 2007-08-29 | 2016-12-13 | Etex Corporation | Bone cement mixing and delivery system and methods of use thereof |
| CN105854074B (zh) * | 2008-02-07 | 2019-10-15 | 生物模拟治疗有限责任公司 | 用于牵引成骨术的组合物和方法 |
| JP2012519556A (ja) * | 2009-03-05 | 2012-08-30 | バイオミメティック セラピューティクス， インコーポレイテッド | 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 |
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2011
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- 2011-12-13 AU AU2011343995A patent/AU2011343995A1/en not_active Abandoned
- 2011-12-13 MX MX2013006697A patent/MX362405B/es active IP Right Grant
- 2011-12-13 WO PCT/US2011/064698 patent/WO2012082773A1/en not_active Ceased
- 2011-12-13 BR BR112013014686A patent/BR112013014686A2/pt not_active IP Right Cessation
- 2011-12-13 JP JP2013544705A patent/JP6116484B2/ja not_active Expired - Fee Related
- 2011-12-13 KR KR1020207013423A patent/KR20200055149A/ko not_active Ceased
- 2011-12-13 CN CN201180067451.1A patent/CN103491888A/zh active Pending
- 2011-12-13 CN CN201810399549.0A patent/CN108498873A/zh active Pending
- 2011-12-13 EP EP11848160.5A patent/EP2651319A4/en not_active Withdrawn
- 2011-12-13 KR KR1020187031242A patent/KR20180121674A/ko not_active Ceased
- 2011-12-13 KR KR1020137015102A patent/KR20140038348A/ko not_active Ceased
- 2011-12-13 CA CA2819258A patent/CA2819258C/en active Active
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2016
- 2016-10-28 JP JP2016211737A patent/JP2017018710A/ja active Pending
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2018
- 2018-05-08 US US15/973,903 patent/US20190365946A1/en not_active Abandoned
- 2018-07-26 JP JP2018139921A patent/JP2018161541A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX362405B (es) | 2019-01-15 |
| AU2011343995A1 (en) | 2013-06-20 |
| JP2018161541A (ja) | 2018-10-18 |
| EP2651319A1 (en) | 2013-10-23 |
| JP6116484B2 (ja) | 2017-04-19 |
| JP2017018710A (ja) | 2017-01-26 |
| MX2013006697A (es) | 2013-10-30 |
| KR20140038348A (ko) | 2014-03-28 |
| JP2013545584A (ja) | 2013-12-26 |
| US20140308332A1 (en) | 2014-10-16 |
| CA2819258A1 (en) | 2012-06-21 |
| CN108498873A (zh) | 2018-09-07 |
| KR20180121674A (ko) | 2018-11-07 |
| EP2651319A4 (en) | 2016-08-17 |
| CN103491888A (zh) | 2014-01-01 |
| WO2012082773A1 (en) | 2012-06-21 |
| US20190365946A1 (en) | 2019-12-05 |
| BR112013014686A2 (pt) | 2016-10-04 |
| KR20200055149A (ko) | 2020-05-20 |
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| EEER | Examination request |
Effective date: 20161207 |