JP2013544811A5 - - Google Patents

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Publication number
JP2013544811A5
JP2013544811A5 JP2013537774A JP2013537774A JP2013544811A5 JP 2013544811 A5 JP2013544811 A5 JP 2013544811A5 JP 2013537774 A JP2013537774 A JP 2013537774A JP 2013537774 A JP2013537774 A JP 2013537774A JP 2013544811 A5 JP2013544811 A5 JP 2013544811A5
Authority
JP
Japan
Prior art keywords
phenyl
isoxazol
trifluoromethyl
chroman
oxadiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2013537774A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013544811A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/058891 external-priority patent/WO2012061459A1/en
Publication of JP2013544811A publication Critical patent/JP2013544811A/ja
Publication of JP2013544811A5 publication Critical patent/JP2013544811A5/ja
Ceased legal-status Critical Current

Links

JP2013537774A 2010-11-03 2011-11-02 自己免疫疾患および血管疾患の治療用のs1p1アゴニストとしての複素環式化合物 Ceased JP2013544811A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40968210P 2010-11-03 2010-11-03
US61/409,682 2010-11-03
PCT/US2011/058891 WO2012061459A1 (en) 2010-11-03 2011-11-02 Heterocyclic compounds as s1p1 agonists for the treatment of autoimmune and vascular diseases

Publications (2)

Publication Number Publication Date
JP2013544811A JP2013544811A (ja) 2013-12-19
JP2013544811A5 true JP2013544811A5 (https=) 2014-11-06

Family

ID=44983720

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013537774A Ceased JP2013544811A (ja) 2010-11-03 2011-11-02 自己免疫疾患および血管疾患の治療用のs1p1アゴニストとしての複素環式化合物

Country Status (6)

Country Link
US (1) US8629282B2 (https=)
EP (1) EP2635573B1 (https=)
JP (1) JP2013544811A (https=)
CN (1) CN103298807A (https=)
ES (1) ES2525298T3 (https=)
WO (1) WO2012061459A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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US8822510B2 (en) 2010-07-20 2014-09-02 Bristol-Myers Squibb Company Substituted 3-phenyl-1,2,4-Oxadiazole compounds
EP2619190B1 (en) 2010-09-24 2015-08-12 Bristol-Myers Squibb Company Substituted oxadiazole compounds and their use as s1p1 agonists
US9115054B2 (en) 2013-02-21 2015-08-25 Bristol-Myers Squibb Company Tetrahydronaphthalenyl compounds useful as sipi agonists
MA40082B1 (fr) 2014-08-20 2019-09-30 Bristol Myers Squibb Co Nouveau compose de substitution sphingosine phosphate utile traitement maladie rhumatisme
ES2877686T3 (es) * 2016-07-22 2021-11-17 Shijiazhuang Sagacity New Drug Dev Co Ltd Agonista S1P1 y aplicación del mismo
JP7252908B2 (ja) 2017-06-14 2023-04-05 トレベナ・インコーポレイテッド S1p1活性を調節するための化合物およびその使用法
KR20200128386A (ko) * 2018-01-18 2020-11-12 스자좡 서개시티 뉴 드러그 디벨롭먼트 컴퍼니, 엘티디. 트리사이클릭 화합물의 결정형 및 염 형태, 및 이의 제조방법
MX2022005766A (es) * 2019-11-19 2022-08-08 Trevena Inc Compuestos y métodos para la preparación de compuestos moduladores de esfingosina 1-fosfato tipo 1 (s1p1).
AU2020389144A1 (en) * 2019-11-20 2022-06-09 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor

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JP4430941B2 (ja) 2002-01-18 2010-03-10 メルク エンド カムパニー インコーポレーテッド Edg受容体作動薬
WO2003061567A2 (en) 2002-01-18 2003-07-31 Merck & Co., Inc. Selective s1p1/edg1 receptor agonists
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JP2005531506A (ja) 2002-03-01 2005-10-20 メルク エンド カムパニー インコーポレーテッド Edg受容体作動薬としてのアミノアルキルホスホネートおよび関連化合物
JP2005533058A (ja) 2002-06-17 2005-11-04 メルク エンド カムパニー インコーポレーテッド Edg受容体アゴニストとしての1−((5−アリール−1,2,4−オキサジアゾール−3−イル)ベンジル)アゼチジン−3−カルボキシラートおよび1−((5−アリール−1,2,4−オキサジアゾール−3−イル)ベンジル)ピロリジン−3−カルボキシラート
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WO2010085582A1 (en) * 2009-01-23 2010-07-29 Bristol-Myers Squibb Company Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
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EP2619190B1 (en) 2010-09-24 2015-08-12 Bristol-Myers Squibb Company Substituted oxadiazole compounds and their use as s1p1 agonists

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