JP2013540714A5 - - Google Patents

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Publication number
JP2013540714A5
JP2013540714A5 JP2013526503A JP2013526503A JP2013540714A5 JP 2013540714 A5 JP2013540714 A5 JP 2013540714A5 JP 2013526503 A JP2013526503 A JP 2013526503A JP 2013526503 A JP2013526503 A JP 2013526503A JP 2013540714 A5 JP2013540714 A5 JP 2013540714A5
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JP
Japan
Prior art keywords
alkyl
group
heterocyclyl
carbocyclyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2013526503A
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English (en)
Japanese (ja)
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JP2013540714A (ja
JP5928737B2 (ja
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Publication date
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Priority claimed from PCT/EP2011/065332 external-priority patent/WO2012032014A1/en
Publication of JP2013540714A publication Critical patent/JP2013540714A/ja
Publication of JP2013540714A5 publication Critical patent/JP2013540714A5/ja
Application granted granted Critical
Publication of JP5928737B2 publication Critical patent/JP5928737B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013526503A 2010-09-06 2011-09-05 エチン誘導体、医薬組成物及びその使用 Expired - Fee Related JP5928737B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10175456 2010-09-06
EP10175456.2 2010-09-06
PCT/EP2011/065332 WO2012032014A1 (en) 2010-09-06 2011-09-05 Ethyne derivatives, pharmaceutical compositions and uses thereof

Publications (3)

Publication Number Publication Date
JP2013540714A JP2013540714A (ja) 2013-11-07
JP2013540714A5 true JP2013540714A5 (https=) 2014-10-23
JP5928737B2 JP5928737B2 (ja) 2016-06-01

Family

ID=44584179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013526503A Expired - Fee Related JP5928737B2 (ja) 2010-09-06 2011-09-05 エチン誘導体、医薬組成物及びその使用

Country Status (4)

Country Link
US (1) US8877754B2 (https=)
EP (1) EP2614054B1 (https=)
JP (1) JP5928737B2 (https=)
WO (1) WO2012032014A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014184104A1 (en) * 2013-05-17 2014-11-20 Boehringer Ingelheim International Gmbh Pyrrolidine derivatives, pharmaceutical compositions and uses thereof
HK1217448A1 (zh) 2013-09-12 2017-01-13 辉瑞大药厂 乙酰辅酶a羧化酶抑制剂用於治疗寻常痤疮的用途
EP2924027A1 (en) * 2014-03-28 2015-09-30 Basf Se Substituted [1,2,4]triazole and imidazole fungicidal compounds
HRP20192009T1 (hr) 2014-12-16 2020-02-07 Novartis Ag Spojevi izoksazol hidroksamske kiseline kao inhibitori lpxc-a
WO2017117708A1 (en) * 2016-01-05 2017-07-13 Hua Medicine (Shanghai) Ltd. Pyrazole derivatives
SG11201810656WA (en) 2016-06-14 2018-12-28 Novartis Ag Crystalline form of (r)-4-(5-(cyclopropylethynyl)isoxazol-3-yl)-n-hydroxy-2-methyl-2-(methylsulfonyl)butanamide as an antibacterial agent
JP2021534215A (ja) * 2018-08-24 2021-12-09 ゼニオプロ ゲーエムベーハー 病的症状の治療における使用のための芳香族分子

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042584A (en) * 1974-08-19 1977-08-16 Merck & Co., Inc. Ethynylaryl phenyl cyclopropyl thiazines and morpholines
JP3894949B2 (ja) * 1993-06-30 2007-03-22 ザ、ウェルカム、ファンデーション、リミテッド 抗アテローム性動脈硬化症ジアリール化合物
KR100502033B1 (ko) * 2000-05-03 2005-07-25 에프. 호프만-라 로슈 아게 알키닐 페닐 헤테로방향족 글루코키나제 활성제
WO2002024656A1 (en) * 2000-09-22 2002-03-28 Nihon Nohyaku Co., Ltd. N-(4-pyrazolyl)amide derivatives, chemicals for agricultural and horticultural use, and usage of the same
DE10219294A1 (de) * 2002-04-25 2003-11-13 Schering Ag Substituierte N-(1,4,5,6-Tetrahydro-cyclopentapyrazol-3-yl)-Derivate, deren Herstellung und Verwendung als Arzneimittel
US7524862B2 (en) 2004-04-14 2009-04-28 Boehringer Ingelheim International Gmbh Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
CA2658362A1 (en) 2006-06-29 2008-01-03 Alantos Pharmaceuticals Holding, Inc. Metalloprotease inhibitors
EA020885B1 (ru) 2008-01-22 2015-02-27 Мерк Патент Гмбх Ингибиторы протеинкиназы и их применение
JP5535931B2 (ja) * 2008-10-27 2014-07-02 武田薬品工業株式会社 二環性化合物

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