JP2013537312A5 - - Google Patents
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- JP2013537312A5 JP2013537312A5 JP2013528779A JP2013528779A JP2013537312A5 JP 2013537312 A5 JP2013537312 A5 JP 2013537312A5 JP 2013528779 A JP2013528779 A JP 2013528779A JP 2013528779 A JP2013528779 A JP 2013528779A JP 2013537312 A5 JP2013537312 A5 JP 2013537312A5
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- ion spectrum
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- 150000002500 ions Chemical class 0.000 claims description 97
- 150000001875 compounds Chemical class 0.000 claims description 61
- 238000001228 spectrum Methods 0.000 claims description 61
- 238000000034 method Methods 0.000 claims description 27
- 238000012986 modification Methods 0.000 claims description 15
- 230000004048 modification Effects 0.000 claims description 15
- 238000004458 analytical method Methods 0.000 claims description 9
- 238000005259 measurement Methods 0.000 claims description 8
- 238000004590 computer program Methods 0.000 claims description 6
- 238000002540 product ion scan Methods 0.000 claims description 6
- 108010026552 Proteome Proteins 0.000 claims description 3
- 150000001720 carbohydrates Chemical class 0.000 claims description 3
- 230000007613 environmental effect Effects 0.000 claims description 3
- 238000013467 fragmentation Methods 0.000 claims description 3
- 238000006062 fragmentation reaction Methods 0.000 claims description 3
- 150000002632 lipids Chemical class 0.000 claims description 3
- 239000002207 metabolite Substances 0.000 claims description 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 230000003595 spectral effect Effects 0.000 claims description 3
- 239000000284 extract Substances 0.000 claims description 2
- 239000002243 precursor Substances 0.000 claims 12
- 238000001514 detection method Methods 0.000 claims 3
- 238000004891 communication Methods 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38313710P | 2010-09-15 | 2010-09-15 | |
| EP10009595.9 | 2010-09-15 | ||
| EP10009595 | 2010-09-15 | ||
| US61/383,137 | 2010-09-15 | ||
| PCT/IB2011/002139 WO2012035412A2 (en) | 2010-09-15 | 2011-09-14 | Data independent acquisition of production spectra and reference spectra library matching |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015168705A Division JP6272610B2 (ja) | 2010-09-15 | 2015-08-28 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013537312A JP2013537312A (ja) | 2013-09-30 |
| JP2013537312A5 true JP2013537312A5 (cg-RX-API-DMAC7.html) | 2014-09-25 |
| JP5875587B2 JP5875587B2 (ja) | 2016-03-02 |
Family
ID=44906224
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013528779A Active JP5875587B2 (ja) | 2010-09-15 | 2011-09-14 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2015168705A Active JP6272610B2 (ja) | 2010-09-15 | 2015-08-28 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2017255162A Active JP6643307B2 (ja) | 2010-09-15 | 2017-12-29 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2020000308A Active JP7026148B2 (ja) | 2010-09-15 | 2020-01-06 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2022020356A Withdrawn JP2022066231A (ja) | 2010-09-15 | 2022-02-14 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2023186438A Active JP7611343B2 (ja) | 2010-09-15 | 2023-10-31 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015168705A Active JP6272610B2 (ja) | 2010-09-15 | 2015-08-28 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2017255162A Active JP6643307B2 (ja) | 2010-09-15 | 2017-12-29 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2020000308A Active JP7026148B2 (ja) | 2010-09-15 | 2020-01-06 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2022020356A Withdrawn JP2022066231A (ja) | 2010-09-15 | 2022-02-14 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
| JP2023186438A Active JP7611343B2 (ja) | 2010-09-15 | 2023-10-31 | 生成イオンスペクトルのデータ独立取得および参照スペクトルライブラリ照合 |
Country Status (6)
| Country | Link |
|---|---|
| US (9) | US8809770B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2617052B1 (cg-RX-API-DMAC7.html) |
| JP (6) | JP5875587B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN103109345B (cg-RX-API-DMAC7.html) |
| CA (1) | CA2810473C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012035412A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2541949C2 (ru) | 2010-07-02 | 2015-02-20 | Дзе Проктер Энд Гэмбл Компани | Филаменты, содержащие активный агент, нетканые полотна и способы их получения |
| CA2803382C (en) | 2010-07-02 | 2015-03-31 | The Procter & Gamble Company | Method for delivering an active agent |
| RU2553294C2 (ru) | 2010-07-02 | 2015-06-10 | Дзе Проктер Энд Гэмбл Компани | Материал в виде полотна и способ его изготовления |
| EP2617052B1 (en) * | 2010-09-15 | 2022-06-08 | DH Technologies Development Pte. Ltd. | Data independent acquisition of production spectra and reference spectra library matching |
| JP5946836B2 (ja) | 2010-11-08 | 2016-07-06 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 質量分析計によって試料を迅速にスクリーニングするためシステムおよび方法 |
| JP5889402B2 (ja) * | 2011-06-03 | 2016-03-22 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | Srmアッセイにおけるバックグラウンド干渉の決定のためのtof−msmsデータの可変xic幅の使用 |
| WO2013044401A1 (en) | 2011-09-28 | 2013-04-04 | BiognoSYS AG | Method for analysis of samples in targeted proteomics applications, computer program product and set of reference peptides |
| US9048072B2 (en) * | 2012-03-12 | 2015-06-02 | Micromass Uk Limited | Method of mass spectrometry and a mass spectrometer |
| EP2834837B1 (en) * | 2012-04-02 | 2020-10-28 | DH Technologies Development Pte. Ltd. | Systems and methods for sequential windowed acquisition across a mass range using an ion trap |
| EP2850645B1 (en) * | 2012-05-18 | 2018-10-31 | DH Technologies Development Pte. Ltd. | Systems and methods for using interleaving window widths in tandem mass spectrometry |
| US9779923B2 (en) * | 2013-03-14 | 2017-10-03 | Leco Corporation | Method and system for tandem mass spectrometry |
| WO2014195783A1 (en) * | 2013-06-05 | 2014-12-11 | Dh Technologies Development Pte. Ltd. | Swathtm data-independent acquisition technology for the detection of host cell protein contaminants in biotherapeutics protein products |
| WO2014195785A1 (en) * | 2013-06-06 | 2014-12-11 | Dh Technologies Development Pte. Ltd. | Improved data quality after demultiplexing of overlapping acquisition windows |
| EP3033763B1 (en) * | 2013-08-13 | 2021-05-26 | Purdue Research Foundation | Sample quantitation with a miniature mass spectrometer |
| EP3157042B1 (en) * | 2013-10-16 | 2021-01-13 | DH Technologies Development Pte. Ltd. | Systems and methods for identifying precursor ions from product ions using arbitrary transmission windowing |
| US9768009B2 (en) * | 2013-10-16 | 2017-09-19 | Dh Technologies Development Pte. Ltd. | Systems and methods for arbitrary quadrupole transmission windowing |
| US9583321B2 (en) * | 2013-12-23 | 2017-02-28 | Thermo Finnigan Llc | Method for mass spectrometer with enhanced sensitivity to product ions |
| US10395909B2 (en) * | 2014-01-16 | 2019-08-27 | Shimadzu Corporation | Mass spectrometer |
| CA2950859A1 (en) * | 2014-06-02 | 2015-12-10 | Dh Technologies Development Pte. Ltd. | Method for converting mass spectral libraries into accurate mass spectral libraries |
| WO2016002047A1 (ja) * | 2014-07-03 | 2016-01-07 | 株式会社島津製作所 | 質量分析データ処理装置 |
| CN106796654A (zh) * | 2014-10-08 | 2017-05-31 | Dh科技发展私人贸易有限公司 | 改进ida光谱输出用于数据库检索 |
| JP6571770B2 (ja) * | 2014-11-13 | 2019-09-04 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 修飾化合物の識別の決定 |
| CN107210181B (zh) * | 2015-02-05 | 2019-11-01 | Dh科技发展私人贸易有限公司 | 在触发碎裂能量的同时迅速扫描宽四极rf窗 |
| EP3268978A1 (en) * | 2015-03-12 | 2018-01-17 | Thermo Finnigan LLC | Methods for data-dependent mass spectrometry of mixed biomolecular analytes |
| EP3283877B1 (en) * | 2015-04-14 | 2024-10-09 | Waters Technologies Corporation | Structural elucidation of isotopically labeled analytes |
| JP6833714B2 (ja) * | 2015-05-13 | 2021-02-24 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | トップダウンタンパク質同定方法 |
| EP3304382B1 (en) | 2015-05-29 | 2025-10-22 | Waters Technologies Corporation | Techniques for processing of mass spectral data |
| JP6833731B2 (ja) * | 2015-06-18 | 2021-02-24 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 確率に基づくライブラリ検索アルゴリズム(prols) |
| US11024492B2 (en) | 2015-07-07 | 2021-06-01 | Institute For Systems Biology | Method to obtain unbiased identification of interaction of test compounds with the proteome |
| EP3335237B1 (en) | 2015-08-13 | 2023-12-06 | DH Technologies Development PTE. Ltd. | Deconvolution of mixed spectra |
| EP3335236B1 (en) * | 2015-08-13 | 2020-05-06 | DH Technologies Development PTE. Ltd. | Library search tolerant to isotopes |
| US11181511B2 (en) | 2015-08-27 | 2021-11-23 | Dh Technologies Development Pte. Ltd. | Rapid scoring of LC-MS/MS peptide data |
| WO2017037563A1 (en) * | 2015-08-31 | 2017-03-09 | Dh Technologies Development Pte. Ltd. | Identification of proteins in the absence of peptide identifications |
| EP3345208A4 (en) | 2015-08-31 | 2019-05-01 | DH Technologies Development PTE. Ltd. | METHOD FOR IMPROVING MS / MS SPECTRAL QUALITY FROM IDA TRIGGERED BY MRM |
| GB2544959B (en) * | 2015-09-17 | 2019-06-05 | Thermo Fisher Scient Bremen Gmbh | Mass spectrometer |
| JP6455603B2 (ja) * | 2015-10-07 | 2019-01-23 | 株式会社島津製作所 | タンデム型質量分析装置 |
| EP3193352A1 (en) | 2016-01-14 | 2017-07-19 | Thermo Finnigan LLC | Methods for mass spectrometric based characterization of biological molecules |
| US10340130B2 (en) | 2016-04-05 | 2019-07-02 | Thermo Finnigan Llc | Data independent acquisition with variable multiplexing degree |
| CN109564227B (zh) * | 2016-07-06 | 2022-06-14 | Dh科技发展私人贸易有限公司 | 结果相依分析-swath数据的迭代分析 |
| WO2018029554A1 (en) * | 2016-08-10 | 2018-02-15 | Dh Technologies Development Pte. Ltd. | Automated spectral library retention time correction |
| CN108061776B (zh) * | 2016-11-08 | 2020-08-28 | 中国科学院大连化学物理研究所 | 一种用于液相色谱-质谱的代谢组学数据峰匹配方法 |
| US9911585B1 (en) | 2016-12-21 | 2018-03-06 | Thermo Finnigan Llc | Data-independent mass spectral data acquisition including data-dependent precursor-ion surveys |
| CN110167639B (zh) | 2017-01-27 | 2022-10-14 | 宝洁公司 | 呈包含泡腾型附聚颗粒的可溶性固体结构形式的组合物 |
| GB2559395B (en) * | 2017-02-03 | 2020-07-01 | Thermo Fisher Scient Bremen Gmbh | High resolution MS1 based quantification |
| JP6702501B2 (ja) * | 2017-03-06 | 2020-06-03 | 株式会社島津製作所 | タンデム型質量分析装置及び該装置用プログラム |
| US9897581B1 (en) | 2017-04-26 | 2018-02-20 | Thermo Finnigan Llc | Variable data-dependent acquisition and dynamic exclusion method for mass spectrometry |
| MX386124B (es) | 2017-05-16 | 2025-03-18 | Procter & Gamble | Composiciones acondicionadoras para el cuidado del cabello en la forma de estructuras sólidas solubles. |
| JP2018205013A (ja) * | 2017-05-31 | 2018-12-27 | 三栄源エフ・エフ・アイ株式会社 | アントシアニン色素の定量方法 |
| EP3410463B1 (en) | 2017-06-02 | 2021-07-28 | Thermo Fisher Scientific (Bremen) GmbH | Hybrid mass spectrometer |
| US11143637B2 (en) * | 2017-08-07 | 2021-10-12 | Agency For Science, Technology And Research | Rapid analysis and identification of lipids from liquid chromatography-mass spectrometry (LC-MS) data |
| US20200234936A1 (en) | 2017-08-31 | 2020-07-23 | Dh Technologies Development Pte. Ltd. | Dynamic Equilibration Time Calculation to Improve MS/MS Dynamic Range |
| EP3688788B1 (en) | 2017-09-29 | 2024-02-21 | DH Technologies Development PTE. Ltd. | Assessing mrm peak purity with isotope selective ms/ms |
| CN109830426B (zh) | 2017-11-23 | 2021-04-02 | 株式会社岛津制作所 | 质谱数据采集方法 |
| CN109828068B (zh) * | 2017-11-23 | 2021-12-28 | 株式会社岛津制作所 | 质谱数据采集及分析方法 |
| EP3740964A4 (en) * | 2018-01-17 | 2021-10-06 | DH Technologies Development Pte. Ltd. | DM SWATH COLLECTION TO IMPROVE MSMS CONFIDENCE |
| CN111902719B (zh) * | 2018-02-19 | 2024-05-07 | 塞尔诺生物科学有限责任公司 | 自动的质谱分析方法和仪器 |
| GB201810273D0 (en) * | 2018-06-22 | 2018-08-08 | Thermo Fisher Scient Bremen Gmbh | Structural analysis of ionised molecules |
| US11666514B2 (en) | 2018-09-21 | 2023-06-06 | The Procter & Gamble Company | Fibrous structures containing polymer matrix particles with perfume ingredients |
| US12130267B2 (en) * | 2018-11-28 | 2024-10-29 | Shimadzu Corporation | Analyzing method for azo compound |
| WO2020110583A1 (ja) * | 2018-11-29 | 2020-06-04 | 株式会社島津製作所 | 有害物質分析システム及び有害物質分析用プログラム |
| EP3660504B1 (en) * | 2018-11-30 | 2025-01-01 | Thermo Fisher Scientific (Bremen) GmbH | Systems and methods for determining mass of an ion species |
| EP3942593A4 (en) * | 2019-03-22 | 2023-01-11 | DH Technologies Development Pte. Ltd. | DETERMINING THE ELUTION OF AGNOSTIC COMPOUNDS |
| CN113631920B (zh) | 2019-05-31 | 2024-04-26 | Dh科技发展私人贸易有限公司 | 用于前体推理的扫描带数据和概率框架的实时编码的方法 |
| JP7381613B2 (ja) | 2019-06-28 | 2023-11-15 | ザ プロクター アンド ギャンブル カンパニー | アニオン性界面活性剤を含有する溶解性固体繊維性物品 |
| GB2590601B (en) * | 2019-11-13 | 2024-01-31 | Thermo Fisher Scient Bremen Gmbh | Method of mass spectrometry |
| CN114616645A (zh) * | 2019-11-14 | 2022-06-10 | Dh科技发展私人贸易有限公司 | 利用正交碎裂方法的质量分析-swath方法 |
| US11138787B2 (en) | 2019-11-25 | 2021-10-05 | Rockwell Collins, Inc. | Efficient transfer of dynamic 3D world model data |
| WO2021122784A1 (en) * | 2019-12-17 | 2021-06-24 | Roche Diagnostics Gmbh | Method and device for multiple transition monitoring |
| CN113552204B (zh) | 2020-04-02 | 2024-06-21 | 株式会社岛津制作所 | 质谱分析方法和质谱系统 |
| JP7359302B2 (ja) * | 2020-05-28 | 2023-10-11 | 株式会社島津製作所 | クロマトグラフ質量分析データ処理方法、クロマトグラフ質量分析装置、及びクロマトグラフ質量分析データ処理用プログラム |
| MX2023001042A (es) | 2020-07-31 | 2023-02-16 | Procter & Gamble | Bolsa fibrosa soluble en agua que contiene granulos para el cuidado del cabello. |
| JP7400698B2 (ja) * | 2020-11-16 | 2023-12-19 | 株式会社島津製作所 | クロマトグラフ質量分析装置 |
| US11721538B2 (en) | 2020-11-17 | 2023-08-08 | Thermo Finnigan Llc | Feeding real time search results of chimeric MS2 spectra into the dynamic exclusion list |
| WO2022107026A2 (en) | 2020-11-19 | 2022-05-27 | Dh Technologies Development Pte. Ltd. | Method of performing ms/ms of high intensity ion beams using a bandpass filtering collision cell to enhance mass spectrometry robustness |
| EP4047371A1 (en) * | 2021-02-18 | 2022-08-24 | Thermo Fisher Scientific (Bremen) GmbH | Method and apparatus for analysing samples of biomolecules using mass spectrometry with data-independent acquisition |
| TW202303150A (zh) | 2021-03-03 | 2023-01-16 | 德商英麥提克生物技術股份有限公司 | Mhc分子的絕對定量方法 |
| US20240177982A1 (en) | 2021-03-30 | 2024-05-30 | Dh Technologies Development Pte. Ltd. | Method for Linear Quantitative Dynamic Range Extension |
| EP4352776A1 (en) | 2021-06-09 | 2024-04-17 | DH Technologies Development Pte. Ltd. | Enhanced q1 mass segregation in scanning swath |
| WO2023002282A1 (en) | 2021-07-23 | 2023-01-26 | Dh Technologies Development Pte. Ltd. | Preventing errors in processing and interpreting mass spectrometry results |
| CN117795643A (zh) | 2021-08-05 | 2024-03-29 | Dh科技发展私人贸易有限公司 | Tof-ms中的空间电荷减少 |
| US20240404813A1 (en) | 2021-08-26 | 2024-12-05 | Dh Technologies Development Pte. Ltd. | Method for enhancing information in dda mass spectrometry |
| WO2023034763A1 (en) | 2021-08-30 | 2023-03-09 | The Procter & Gamble Company | Dissolvable solid structure comprising first and second polymeric structurants |
| WO2023031870A1 (en) | 2021-09-03 | 2023-03-09 | Dh Technologies Development Pte. Ltd. | Prediction of precursor charge state in dm-swath analysis |
| US20250006307A1 (en) | 2021-09-08 | 2025-01-02 | Dh Technologies Development Pte. Ltd. | Identification of Changing Pathways or Disease Indicators Through Cluster Analysis |
| CN118525336A (zh) | 2021-10-05 | 2024-08-20 | Dh科技发展私人贸易有限公司 | 用于增强对dia数据的完整数据提取的方法 |
| CN118556276A (zh) | 2021-11-19 | 2024-08-27 | Dh科技发展私人贸易有限公司 | 用于使用模拟检测系统进行降噪和离子速率估计的方法 |
| US12009194B2 (en) * | 2021-12-14 | 2024-06-11 | Thermo Finnigan Llc | Mass spectrometry data-independent analysis methods with improved efficiency |
| CN118901104A (zh) | 2022-02-04 | 2024-11-05 | Dh科技发展私人贸易有限公司 | 使用质谱进行化合物识别 |
| US20250259707A1 (en) | 2022-04-12 | 2025-08-14 | Dh Technologies Development Pte. Ltd. | Optimization of Processing Parameters for Top/Middle Down MS/MS |
| WO2023199137A1 (en) | 2022-04-12 | 2023-10-19 | Dh Technologies Development Pte. Ltd. | Single panel representation of multiple charge evidence linked to a bond in the protein |
| WO2023199138A1 (en) | 2022-04-12 | 2023-10-19 | Dh Technologies Development Pte. Ltd. | Scoring of whole protein msms spectra based on a bond relevance score |
| US20250259713A1 (en) | 2022-04-12 | 2025-08-14 | Dh Technologies Development Pte. Ltd. | Library Search Using Deep Learning Based Spectral Compression |
| WO2023203620A1 (ja) | 2022-04-18 | 2023-10-26 | 株式会社島津製作所 | 質量分析装置 |
| GB2621395B (en) | 2022-08-12 | 2025-02-05 | Thermo Fisher Scient Bremen Gmbh | Methods and mass spectrometry systems for acquiring mass spectral data |
| GB2621393B (en) | 2022-08-12 | 2024-12-25 | Thermo Fisher Scient Bremen Gmbh | Methods and mass spectrometry systems for acquiring mass spectral data |
| GB2621394B (en) | 2022-08-12 | 2024-12-04 | Thermo Fisher Scient Bremen Gmbh | Methods and Mass Spectrometry Systems for Acquiring Mass Spectral Data |
| WO2024075058A1 (en) | 2022-10-06 | 2024-04-11 | Dh Technologies Development Pte. Ltd. | Reducing data complexity for subsequent rt alignment |
| WO2024075065A1 (en) | 2022-10-06 | 2024-04-11 | Dh Technologies Development Pte. Ltd. | Creation of realistic ms/ms spectra for putative designer drugs |
| EP4630584A1 (en) | 2022-12-07 | 2025-10-15 | DH Technologies Development Pte. Ltd. | De novo sequencing of dna |
| EP4649518A1 (en) | 2023-01-09 | 2025-11-19 | DH Technologies Development Pte. Ltd. | Sequencing of morpholino oligomers using electron capture dissociation |
| FR3149423B1 (fr) | 2023-06-05 | 2025-05-30 | Synchrotron Soleil | Procédé de reconstruction d’un spectre de masse |
| GB2631473A (en) | 2023-06-30 | 2025-01-08 | Thermo Fisher Scient Bremen Gmbh | Quantifying a substance present in a sample |
| GB2700086A (en) * | 2023-07-21 | 2025-09-17 | Thermo Fisher Scient Bremen Gmbh | Compound assembly |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3699333A (en) * | 1968-10-23 | 1972-10-17 | Franklin Gno Corp | Apparatus and methods for separating, concentrating, detecting, and measuring trace gases |
| US3626178A (en) * | 1970-02-20 | 1971-12-07 | Franklin Gno Corp | Gas or liquid chromatograph with detector employing ion-molecule reactions and ion drift |
| US3812355A (en) * | 1971-12-09 | 1974-05-21 | Gno F Corp | Apparatus and methods for measuring ion mass as a function of mobility |
| US4023398A (en) * | 1975-03-03 | 1977-05-17 | John Barry French | Apparatus for analyzing trace components |
| EP0182163B1 (en) | 1984-11-07 | 1990-08-01 | General Electric Company | Silane derivatives which improve the properties of polyphenylene oxide-polyamide compositions |
| US4818862A (en) * | 1987-10-21 | 1989-04-04 | Iowa State University Research Foundation, Inc. | Characterization of compounds by time-of-flight measurement utilizing random fast ions |
| US5179278A (en) * | 1991-08-23 | 1993-01-12 | Mds Health Group Limited | Multipole inlet system for ion traps |
| US5455417A (en) * | 1994-05-05 | 1995-10-03 | Sacristan; Emilio | Ion mobility method and device for gas analysis |
| US6573492B2 (en) * | 1999-12-27 | 2003-06-03 | Hitachi, Ltd. | Mass spectrometric analysis method and apparatus using the method |
| GB2364168B (en) * | 2000-06-09 | 2002-06-26 | Micromass Ltd | Methods and apparatus for mass spectrometry |
| CA2340150C (en) * | 2000-06-09 | 2005-11-22 | Micromass Limited | Methods and apparatus for mass spectrometry |
| EP1327256A2 (en) * | 2000-10-11 | 2003-07-16 | Ciphergen Biosystems, Inc. | Apparatus and methods for affinity capture tandem mass spectrometry |
| US6524803B2 (en) * | 2000-12-19 | 2003-02-25 | Agilent Technologies, Inc. | Deconvolution method and apparatus for analyzing compounds |
| AU2002250180A1 (en) * | 2001-02-23 | 2002-09-12 | Maxygen, Inc. | Screening for enzyme stereoselectivity utilizing mass spectrometry |
| DE10145904A1 (de) * | 2001-09-18 | 2003-04-10 | Bruker Daltonik Gmbh | Verfahren zur Aufklärung des Metabolismus |
| JP3990889B2 (ja) * | 2001-10-10 | 2007-10-17 | 株式会社日立ハイテクノロジーズ | 質量分析装置およびこれを用いる計測システム |
| WO2003087770A2 (en) * | 2002-04-12 | 2003-10-23 | Northeastern University | Matched filtration with experimental noise determination for denoising, peak picking and quantitation in lc-ms |
| AU2003261074A1 (en) * | 2002-05-20 | 2003-12-02 | Jason M. Hogan | Protein identification from protein product ion spectra |
| US20040014143A1 (en) * | 2002-05-29 | 2004-01-22 | Haskins William E. | Method and apparatus for detecting and monitoring peptides, and peptides identified therewith |
| NZ520019A (en) * | 2002-07-05 | 2005-02-25 | Syft Technologies Ltd | A method of assaying the antioxidant activity of pure compounds, extracts and biological fluids using SIFT-MS technology |
| GB2390935A (en) * | 2002-07-16 | 2004-01-21 | Anatoli Nicolai Verentchikov | Time-nested mass analysis using a TOF-TOF tandem mass spectrometer |
| GB0305796D0 (en) * | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
| DE60325482D1 (de) * | 2002-08-22 | 2009-02-05 | Applera Corp | Verfahren zur charakterisierung von biomolekülen mittels resultat-gesteuerter strategie |
| JP3534191B1 (ja) * | 2002-12-26 | 2004-06-07 | 日本電気株式会社 | 質量分析法を利用するペプチドc末端アミノ酸配列解析方法 |
| CN100550275C (zh) * | 2003-01-24 | 2009-10-14 | 萨莫芬尼根有限责任公司 | 控制质量分析器中的离子数目 |
| DE112004000453B4 (de) * | 2003-03-19 | 2021-08-12 | Thermo Finnigan Llc | Erlangen von Tandem-Massenspektrometriedaten für Mehrfachstammionen in einer Ionenpopulation |
| US7459693B2 (en) * | 2003-04-04 | 2008-12-02 | Bruker Daltonics, Inc. | Ion guide for mass spectrometers |
| US9357755B2 (en) * | 2003-10-28 | 2016-06-07 | The University Of Wyoming | Production of human glycosylated proteins in silk worm |
| US7365309B2 (en) * | 2003-12-22 | 2008-04-29 | Micromass Uk Limited | Mass spectrometer |
| US20070054345A1 (en) * | 2004-05-19 | 2007-03-08 | Hunter Christie L | Expression quantification using mass spectrometry |
| US20080206737A1 (en) * | 2004-05-19 | 2008-08-28 | Hunter Christie L | Expression quantification using mass spectrometry |
| NZ534909A (en) * | 2004-08-26 | 2005-10-28 | Syft Technologies Ltd | A method of assaying the antioxidant activity of oils and lipids using SIFT-MS technology |
| JP4643206B2 (ja) * | 2004-09-03 | 2011-03-02 | 株式会社日立ハイテクノロジーズ | 質量分析装置 |
| CN100390537C (zh) * | 2004-11-12 | 2008-05-28 | 中国科学院计算技术研究所 | 用串联质谱中碎片离子的同位素峰预测离子分子式的方法 |
| JP2006322899A (ja) * | 2005-05-20 | 2006-11-30 | Hitachi Ltd | ガスモニタリング装置 |
| DE102005025499B4 (de) * | 2005-06-03 | 2007-09-27 | Bruker Daltonik Gmbh | Massenspektrometrische Gemischanalyse |
| US7972770B2 (en) * | 2005-08-16 | 2011-07-05 | Memorial Sloan-Kettering Cancer Center | Methods of detection of cancer using peptide profiles |
| GB2432712B (en) * | 2005-11-23 | 2007-12-27 | Micromass Ltd | Mass spectrometer |
| JP4782579B2 (ja) * | 2006-02-15 | 2011-09-28 | 株式会社日立ハイテクノロジーズ | タンデム型質量分析システム及び方法 |
| US20080173807A1 (en) * | 2006-04-11 | 2008-07-24 | Oh-Kyu Yoon | Fragmentation modulation mass spectrometry |
| US7915008B2 (en) * | 2006-04-27 | 2011-03-29 | Syddansk Universitet | Methods for isolation and analysis of sialylated and phosphorylated peptides |
| GB0609253D0 (en) * | 2006-05-10 | 2006-06-21 | Micromass Ltd | Mass spectrometer |
| JP4577266B2 (ja) * | 2006-05-16 | 2010-11-10 | 株式会社島津製作所 | クロマトグラフ質量分析装置 |
| US7956320B2 (en) * | 2006-05-18 | 2011-06-07 | Shimadzu Corporation | Data processor for mass spectrometer |
| JP5424872B2 (ja) * | 2006-05-26 | 2014-02-26 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 質量分析法を実施するための装置および方法 |
| JP5039330B2 (ja) * | 2006-06-30 | 2012-10-03 | 株式会社日立ハイテクノロジーズ | 質量分析システム |
| US8271203B2 (en) * | 2006-07-12 | 2012-09-18 | Dh Technologies Development Pte. Ltd. | Methods and systems for sequence-based design of multiple reaction monitoring transitions and experiments |
| US7638762B2 (en) * | 2006-09-29 | 2009-12-29 | Agilent Technologies, Inc. | Systems and methods for decreasing settling times in MS/MS |
| GB0622689D0 (en) | 2006-11-14 | 2006-12-27 | Thermo Electron Bremen Gmbh | Method of operating a multi-reflection ion trap |
| GB0704764D0 (en) * | 2007-03-12 | 2007-04-18 | Electrophoretics Ltd | Isobarically labelled reagents and methods of their use |
| US20100311176A1 (en) * | 2007-05-23 | 2010-12-09 | Applied Biosystems, Llc | Method of mass analysis of target molecules in complex mixtures |
| JP4905265B2 (ja) * | 2007-06-18 | 2012-03-28 | 株式会社島津製作所 | クロマトグラフ質量分析装置用データ処理装置 |
| EP2210108B1 (en) * | 2007-10-10 | 2011-12-07 | BG Medicine, Inc. | Methods for detecting major adverse cardiovascular and cerebrovascular events |
| US8030612B2 (en) * | 2007-11-09 | 2011-10-04 | Dh Technologies Development Pte. Ltd. | High resolution excitation/isolation of ions in a low pressure linear ion trap |
| EP2232524A4 (en) * | 2007-12-04 | 2016-06-08 | Dh Technologies Dev Pte Ltd | SYSTEMS AND METHODS FOR ANALYZING SUBSTANCES USING A MASS SPECTROMETER |
| US7897405B2 (en) * | 2008-02-11 | 2011-03-01 | Thermo Finnigan Llc | Method for identifying the elution time of an analyte |
| CN102067273B (zh) * | 2008-03-05 | 2013-12-11 | 株式会社岛津制作所 | 质量分析装置 |
| CA2718535C (en) * | 2008-03-20 | 2017-06-06 | Dh Technologies Development Pte. Ltd. | Systems and methods for analyzing substances using a mass spectrometer |
| US8841423B2 (en) * | 2008-04-28 | 2014-09-23 | University Of Iowa Research Foundation | Monoclonal antibodies specific for oxidized calcium/calmodulin dependent protein kinase II |
| GB0811298D0 (en) * | 2008-06-19 | 2008-07-30 | Trillion Genomics Ltd | Characterising polypeptides |
| JP4973628B2 (ja) * | 2008-08-29 | 2012-07-11 | 株式会社島津製作所 | クロマトグラフ質量分析データ解析方法及び装置 |
| JP4941437B2 (ja) * | 2008-09-12 | 2012-05-30 | 株式会社島津製作所 | 四重極型質量分析装置 |
| EP2380184A1 (en) * | 2009-01-09 | 2011-10-26 | Mds Analytical Technologies | Mass spectrometer |
| GB0900973D0 (en) * | 2009-01-21 | 2009-03-04 | Micromass Ltd | Method and apparatus for performing MS^N |
| US8269166B2 (en) * | 2009-02-05 | 2012-09-18 | Shimadzu Corporation | MS/MS mass spectrometer |
| WO2010129187A1 (en) * | 2009-05-08 | 2010-11-11 | Thermo Finnigan Llc | Methods and systems for matching productions to precursor ions |
| WO2010135831A1 (en) * | 2009-05-27 | 2010-12-02 | Dh Technologies Development Pte. Ltd. | Linear ion trap for msms |
| JP5852654B2 (ja) | 2010-09-08 | 2016-02-03 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | タンデム質量分析計において可変質量選択窓幅を用いるためのシステムおよび方法 |
| EP2617052B1 (en) * | 2010-09-15 | 2022-06-08 | DH Technologies Development Pte. Ltd. | Data independent acquisition of production spectra and reference spectra library matching |
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