JP2013536195A5 - - Google Patents

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Publication number
JP2013536195A5
JP2013536195A5 JP2013524318A JP2013524318A JP2013536195A5 JP 2013536195 A5 JP2013536195 A5 JP 2013536195A5 JP 2013524318 A JP2013524318 A JP 2013524318A JP 2013524318 A JP2013524318 A JP 2013524318A JP 2013536195 A5 JP2013536195 A5 JP 2013536195A5
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JP
Japan
Prior art keywords
oligonucleotide
chelate complex
pharmaceutical composition
complex comprises
chelate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2013524318A
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English (en)
Japanese (ja)
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JP2013536195A (ja
JP5775581B2 (ja
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Publication date
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Priority claimed from PCT/CA2011/000956 external-priority patent/WO2012021985A1/en
Publication of JP2013536195A publication Critical patent/JP2013536195A/ja
Publication of JP2013536195A5 publication Critical patent/JP2013536195A5/ja
Application granted granted Critical
Publication of JP5775581B2 publication Critical patent/JP5775581B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013524318A 2010-08-20 2011-08-18 オリゴヌクレオチドキレート錯体 Active JP5775581B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37525710P 2010-08-20 2010-08-20
US61/375,257 2010-08-20
PCT/CA2011/000956 WO2012021985A1 (en) 2010-08-20 2011-08-18 Oligonucleotide chelate complexes

Publications (3)

Publication Number Publication Date
JP2013536195A JP2013536195A (ja) 2013-09-19
JP2013536195A5 true JP2013536195A5 (https=) 2014-04-10
JP5775581B2 JP5775581B2 (ja) 2015-09-09

Family

ID=45594559

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013524318A Active JP5775581B2 (ja) 2010-08-20 2011-08-18 オリゴヌクレオチドキレート錯体

Country Status (35)

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US (2) US8513211B2 (https=)
EP (1) EP2605794B1 (https=)
JP (1) JP5775581B2 (https=)
KR (3) KR101606495B1 (https=)
CN (2) CN103768086B (https=)
AU (1) AU2011291401B2 (https=)
BR (1) BR112013003875B1 (https=)
CA (2) CA2806616C (https=)
CL (1) CL2013000445A1 (https=)
CO (1) CO6670525A2 (https=)
CR (1) CR20130069A (https=)
CU (1) CU20130022A7 (https=)
CY (1) CY1118207T1 (https=)
DK (1) DK2605794T3 (https=)
DO (1) DOP2013000041A (https=)
EA (1) EA026660B1 (https=)
EC (1) ECSP13012449A (https=)
ES (1) ES2598556T3 (https=)
GT (1) GT201300040A (https=)
HR (1) HRP20161333T1 (https=)
HU (1) HUE029521T2 (https=)
IL (1) IL224237A (https=)
LT (1) LT2605794T (https=)
MX (1) MX340294B (https=)
MY (1) MY160961A (https=)
NZ (1) NZ606364A (https=)
PH (1) PH12013500192B1 (https=)
PL (1) PL2605794T3 (https=)
PT (1) PT2605794T (https=)
RS (1) RS55245B1 (https=)
SG (1) SG187165A1 (https=)
SI (1) SI2605794T1 (https=)
SM (1) SMT201600370B (https=)
WO (1) WO2012021985A1 (https=)
ZA (1) ZA201300497B (https=)

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AU2007282224B2 (en) 2006-08-11 2013-08-29 Vico Therapeutics B.V. Methods and means for treating DNA repeat instability associated genetic disorders
CA2723672C (en) 2007-05-11 2019-09-03 Adynxx, Inc. Gene expression and pain
AU2008317566B2 (en) 2007-10-26 2014-05-01 Academisch Ziekenhuis Leiden Means and methods for counteracting muscle disorders
EP2119783A1 (en) 2008-05-14 2009-11-18 Prosensa Technologies B.V. Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means
CN112251436A (zh) 2012-01-27 2021-01-22 比奥马林技术公司 治疗杜兴型肌营养不良症和贝克型肌营养不良症的具有改善特性的rna调节性寡核苷酸
SMT201700339T1 (it) 2012-04-23 2017-09-07 Biomarin Tech Bv Oligonucleotidi di modulazione dell'rna con caratteristiche migliorate per il trattamento dei disturbi neuromuscolari
EP3511022A1 (en) * 2012-05-10 2019-07-17 Adynxx, Inc. Formulations for the delivery of active ingredients
MY168778A (en) * 2012-05-18 2018-12-04 Replicor Inc Oligonucleotide chelate complex-polypeptide compositions and methods
AR091065A1 (es) * 2012-05-18 2014-12-30 Replicor Inc Una formulacion farmaceutica que comprende un quelato de oligonucleotidos antiviral para el tratamiento de una infeccion antiviral
EP2870246B1 (en) 2012-07-03 2019-09-11 BioMarin Technologies B.V. Oligonucleotide for the treatment of muscular dystrophy patients
AU2013308045B2 (en) * 2012-08-30 2018-10-04 Replicor Inc. Methods for the treatment of hepatitis B and hepatitis D infections
HRP20231400T1 (hr) 2014-07-10 2024-02-16 Replicor Inc. Kelirani fosforotioirani polimeri nukleinskih kiselina, namijenjeni upotrebi u kombinaciji s inhibitorom hbv polimeraze u liječenju infekcija virusima hepatitisa b i hepatitisa d
JP6705807B2 (ja) 2014-08-15 2020-06-03 エーダイニクス インコーポレイテッド 疼痛を治療するためのオリゴヌクレオチドデコイ
WO2016030863A1 (en) 2014-08-29 2016-03-03 Glaxosmithkline Intellectual Property Development Limited Compounds and methods for treating viral infections
AU2016250576C1 (en) * 2015-04-23 2021-05-06 Geron Corporation Methods of polynucleotide preparation using multivalent cation salt compositions
US11166976B2 (en) 2018-11-08 2021-11-09 Aligos Therapeutics, Inc. S-antigen transport inhibiting oligonucleotide polymers and methods
PE20211783A1 (es) * 2018-11-08 2021-09-08 Aligos Therapeutics Inc Polimeros oligonucleotidos que inhiben el transporte de antigenos y metodos
WO2021198958A1 (en) 2020-04-01 2021-10-07 Janssen Biopharma, Inc. Nucleic acid polymers
WO2022109129A1 (en) * 2020-11-20 2022-05-27 Aligos Therapeutics, Inc. Conjugates of s-antigen transport inhibiting oligonucleotide polymers having enhanced liver targeting
TW202245809A (zh) 2020-12-18 2022-12-01 美商詹森藥物公司 用於治療b型肝炎病毒感染之組合療法
WO2022152869A1 (en) 2021-01-15 2022-07-21 Janssen Sciences Ireland Unlimited Company Use of oligonucleotides for individuals with hepatic impairment
EP4367241A1 (en) 2021-07-09 2024-05-15 GlaxoSmithKline Intellectual Property (No.3) Limited Use of oligonucleotides for individuals with renal impairment
EP4728073A1 (en) * 2023-06-16 2026-04-22 Ractigen Therapeutics Oligonucleotide formulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001514873A (ja) * 1997-08-20 2001-09-18 ソーマジェニックス インコーポレイテッド 結合特性が改善されたアンチセンスおよびアンチジーン治療薬並びにそれらの使用方法
JP3667047B2 (ja) * 1997-09-12 2005-07-06 キヤノン株式会社 人工核酸およびその製造方法、デオキシリボフラノース化合物、リボフラノース化合物およびこれらの製造方法
US6653467B1 (en) * 2000-04-26 2003-11-25 Jcr Pharmaceutical Co., Ltd. Medicament for treatment of Duchenne muscular dystrophy
JP4836366B2 (ja) * 2000-08-25 2011-12-14 雅文 松尾 デュシェンヌ型筋ジストロフィー治療剤
US20070105116A1 (en) 2003-09-02 2007-05-10 Japan Science And Technology Agency Metal complex type nucleic acid
WO2005026188A1 (ja) 2003-09-08 2005-03-24 Japan Science And Technology Agency 金属錯体型核酸
JP2009500020A (ja) * 2005-07-01 2009-01-08 バイオヴェリス コーポレイション 核酸を検出、増幅および/また単離するための組成物および方法
WO2009065181A1 (en) * 2007-11-21 2009-05-28 Apollo Life Sciences Limited Nanostructures suitable for delivery of agents

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