JP2013533268A - 糖尿病及び代謝障害を治療する組み合わせ医薬組成物及び方法 - Google Patents

糖尿病及び代謝障害を治療する組み合わせ医薬組成物及び方法 Download PDF

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JP2013533268A
JP2013533268A JP2013520235A JP2013520235A JP2013533268A JP 2013533268 A JP2013533268 A JP 2013533268A JP 2013520235 A JP2013520235 A JP 2013520235A JP 2013520235 A JP2013520235 A JP 2013520235A JP 2013533268 A JP2013533268 A JP 2013533268A
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pharmaceutical composition
activation
seq
antibody against
insulin receptor
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JP2013533268A5 (cg-RX-API-DMAC10.html
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イリイチ・エプシテイン オレグ
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Priority claimed from RU2010130348/15A external-priority patent/RU2531048C2/ru
Priority claimed from RU2011127051/15A external-priority patent/RU2509572C2/ru
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Publication of JP2013533268A publication Critical patent/JP2013533268A/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2013520235A 2010-07-21 2011-07-15 糖尿病及び代謝障害を治療する組み合わせ医薬組成物及び方法 Pending JP2013533268A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
RU2010130348 2010-07-21
RU2010130348/15A RU2531048C2 (ru) 2010-07-21 2010-07-21 Лекарственное средство для уменьшения резистентности к инсулину и лечения сахарного диабета и способ повышения эффективности лечения сахарного диабета инсулином и/или гипогликемическими препаратами
RU2011127051/15A RU2509572C2 (ru) 2011-07-01 2011-07-01 Лекарственное средство для уменьшения резистентности к инсулину и для лечения сахарного диабета, способ уменьшения резистентности к инсулину, способ лечения сахарного диабета и способ лечения сахарного диабета инсулином и/или гипогликемическими препаратами
RU2011127051 2011-07-01
PCT/IB2011/002177 WO2012010966A2 (en) 2010-07-21 2011-07-15 A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders

Related Child Applications (1)

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JP2016131729A Division JP2016222684A (ja) 2010-07-21 2016-07-01 糖尿病及び代謝障害を治療する組み合わせ医薬組成物及び方法

Publications (2)

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JP2013533268A true JP2013533268A (ja) 2013-08-22
JP2013533268A5 JP2013533268A5 (cg-RX-API-DMAC10.html) 2014-04-24

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JP2013520235A Pending JP2013533268A (ja) 2010-07-21 2011-07-15 糖尿病及び代謝障害を治療する組み合わせ医薬組成物及び方法
JP2016131729A Pending JP2016222684A (ja) 2010-07-21 2016-07-01 糖尿病及び代謝障害を治療する組み合わせ医薬組成物及び方法

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US (1) US8617555B2 (cg-RX-API-DMAC10.html)
EP (2) EP2595658A2 (cg-RX-API-DMAC10.html)
JP (2) JP2013533268A (cg-RX-API-DMAC10.html)
KR (2) KR20130103486A (cg-RX-API-DMAC10.html)
CN (1) CN103118707A (cg-RX-API-DMAC10.html)
AR (1) AR082312A1 (cg-RX-API-DMAC10.html)
AU (1) AU2011281240B2 (cg-RX-API-DMAC10.html)
BR (1) BR112013001299A2 (cg-RX-API-DMAC10.html)
CA (1) CA2805961A1 (cg-RX-API-DMAC10.html)
CL (1) CL2013000200A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ2013124A3 (cg-RX-API-DMAC10.html)
DE (1) DE112011102396T5 (cg-RX-API-DMAC10.html)
DK (1) DK201370089A (cg-RX-API-DMAC10.html)
EA (1) EA029847B1 (cg-RX-API-DMAC10.html)
EE (1) EE05761B1 (cg-RX-API-DMAC10.html)
ES (1) ES2445846R1 (cg-RX-API-DMAC10.html)
FI (1) FI20135152L (cg-RX-API-DMAC10.html)
FR (1) FR2962913A1 (cg-RX-API-DMAC10.html)
GB (2) GB2496799B (cg-RX-API-DMAC10.html)
IT (1) ITTO20110627A1 (cg-RX-API-DMAC10.html)
LT (1) LT5980B (cg-RX-API-DMAC10.html)
MX (1) MX2013000804A (cg-RX-API-DMAC10.html)
MY (1) MY160979A (cg-RX-API-DMAC10.html)
NO (1) NO20130265A1 (cg-RX-API-DMAC10.html)
NZ (1) NZ606964A (cg-RX-API-DMAC10.html)
PE (1) PE20130815A1 (cg-RX-API-DMAC10.html)
PH (1) PH12013500140A1 (cg-RX-API-DMAC10.html)
SE (1) SE1350212A1 (cg-RX-API-DMAC10.html)
SG (1) SG187578A1 (cg-RX-API-DMAC10.html)
WO (1) WO2012010966A2 (cg-RX-API-DMAC10.html)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013533269A (ja) * 2010-07-21 2013-08-22 イリイチ・エプシテイン オレグ 組み合わせ医薬組成物及び呼吸器の疾患又は状態に関連する疾患及び状態を治療する方法
JP2013536174A (ja) * 2010-07-21 2013-09-19 イリイチ・エプシテイン オレグ 組み合わせ医薬組成物並びに回転性めまい、動揺病及び自律神経血管ジストニアを治療する方法
JP2013537532A (ja) * 2010-08-06 2013-10-03 イリイチ・エプシテイン オレグ 感染性疾患を治療及び予防する組み合わせ医薬組成物及び方法

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RU2181297C2 (ru) 2000-06-20 2002-04-20 Эпштейн Олег Ильич Способ лечения патологического синдрома и лекарственное средство
UA76638C2 (en) 2002-08-02 2006-08-15 Oleh Illich Epshtein Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon
RU2309732C1 (ru) * 2006-03-13 2007-11-10 Олег Ильич Эпштейн Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата
WO2007149010A1 (en) * 2006-06-06 2007-12-27 Oleg Iliich Epshtein Medicinal agent for treating fatness, diabetes, and diseases associated with impaired glucose tolerance
CA2804966A1 (en) * 2010-07-15 2012-01-19 Oleg Iliich Epshtein A method of increasing the effect of an activated-potentiated form of an antibody
CN103154028A (zh) 2010-07-15 2013-06-12 奥列格·伊里奇·爱泼斯坦 复合药物组合物以及对神经退行性疾病相关的疾病或病症进行治疗的方法
WO2012007847A2 (en) 2010-07-15 2012-01-19 Oleg Iliich Epshtein Pharmaceutical compositions and methods of treatment
CN103119061A (zh) 2010-07-21 2013-05-22 奥列格·伊里奇·爱泼斯坦 治疗注意力不足过动症的方法
TWI588153B (zh) * 2012-05-18 2017-06-21 中國醫藥大學 多胜肽、編碼該多胜肽之核酸分子、以及該多胜肽之應用
RU2013111962A (ru) 2013-03-18 2014-09-27 Олег Ильич Эпштейн Способ определения выраженности модифицирующей активности, ассоциированной с носителем
RU2013111961A (ru) 2013-03-18 2014-09-27 Олег Ильич Эпштейн Способ определения выраженности модифицирующей активности, ассоциированной с носителем

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JP2007518692A (ja) * 2004-01-20 2007-07-12 アステラス製薬株式会社 勃起不全治療方法
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JP2013532182A (ja) * 2010-07-15 2013-08-15 イリイチ・エプシテイン オレグ 組み合わせ医薬組成物及び神経変性疾患に関連する疾患又は状態を治療する方法
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JP2013535436A (ja) * 2010-07-15 2013-09-12 イリイチ・エプシテイン オレグ 医薬組成物及び治療方法
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UA76641C2 (uk) 2002-08-02 2006-08-15 Олєг Ільіч Епштєйн Гомеопатичний лікарський засіб та спосіб лікування захворювань передміхурової залози
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EP1547612A1 (en) * 2002-08-02 2005-06-29 Oleg Iliich Epshtein Medicinal agent and method for curing erectile dysfunction
JP2007518692A (ja) * 2004-01-20 2007-07-12 アステラス製薬株式会社 勃起不全治療方法
JP2009539827A (ja) * 2006-06-06 2009-11-19 オレグ イリッチ エプシュテイン 肥満、真性糖尿病及び耐糖能異常を伴う疾患の治療用薬剤
JP2013532182A (ja) * 2010-07-15 2013-08-15 イリイチ・エプシテイン オレグ 組み合わせ医薬組成物及び神経変性疾患に関連する疾患又は状態を治療する方法
JP2013535436A (ja) * 2010-07-15 2013-09-12 イリイチ・エプシテイン オレグ 医薬組成物及び治療方法
JP2013538186A (ja) * 2010-07-15 2013-10-10 イリイチ・エプシテイン オレグ 活性化増強型抗体の効果を増大させる方法
JP2013533269A (ja) * 2010-07-21 2013-08-22 イリイチ・エプシテイン オレグ 組み合わせ医薬組成物及び呼吸器の疾患又は状態に関連する疾患及び状態を治療する方法
JP2013536174A (ja) * 2010-07-21 2013-09-19 イリイチ・エプシテイン オレグ 組み合わせ医薬組成物並びに回転性めまい、動揺病及び自律神経血管ジストニアを治療する方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013533269A (ja) * 2010-07-21 2013-08-22 イリイチ・エプシテイン オレグ 組み合わせ医薬組成物及び呼吸器の疾患又は状態に関連する疾患及び状態を治療する方法
JP2013536174A (ja) * 2010-07-21 2013-09-19 イリイチ・エプシテイン オレグ 組み合わせ医薬組成物並びに回転性めまい、動揺病及び自律神経血管ジストニアを治療する方法
JP2013537532A (ja) * 2010-08-06 2013-10-03 イリイチ・エプシテイン オレグ 感染性疾患を治療及び予防する組み合わせ医薬組成物及び方法

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BR112013001299A2 (pt) 2017-11-21
LT5980B (lt) 2013-12-27
PH12013500140A1 (en) 2013-03-11
FI20135152A7 (fi) 2013-02-21
GB201707872D0 (en) 2017-06-28
EA029847B1 (ru) 2018-05-31
WO2012010966A2 (en) 2012-01-26
NZ606964A (en) 2015-08-28
SG187578A1 (en) 2013-03-28
EE201300007A (et) 2013-08-15
EE05761B1 (et) 2016-03-15
JP2016222684A (ja) 2016-12-28
EP2595658A2 (en) 2013-05-29
CL2013000200A1 (es) 2015-01-23
GB2496799B (en) 2017-11-22
DE112011102396T5 (de) 2013-05-02
NO20130265A1 (no) 2013-04-18
EP3693018A1 (en) 2020-08-12
AR082312A1 (es) 2012-11-28
US20130064824A1 (en) 2013-03-14
AU2011281240B2 (en) 2016-07-07
LT2013018A (lt) 2013-10-25
KR20180127515A (ko) 2018-11-28
ES2445846R1 (es) 2015-01-02
FI20135152L (fi) 2013-02-21
MY160979A (en) 2017-03-31
KR20130103486A (ko) 2013-09-23
GB2552405A (en) 2018-01-24
GB2552405B (en) 2018-05-30
FR2962913A1 (fr) 2012-01-27
ES2445846A2 (es) 2014-03-05
US8617555B2 (en) 2013-12-31
CZ2013124A3 (cs) 2013-06-12
ITTO20110627A1 (it) 2012-01-22
DK201370089A (en) 2013-02-19
PE20130815A1 (es) 2013-07-18
GB201302924D0 (en) 2013-04-03
GB2496799A (en) 2013-05-22
CA2805961A1 (en) 2012-01-26
MX2013000804A (es) 2013-10-28
CN103118707A (zh) 2013-05-22
WO2012010966A3 (en) 2012-03-29
AU2011281240A1 (en) 2013-03-07
EA201300124A1 (ru) 2013-12-30
SE1350212A1 (sv) 2013-04-22

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