JP2013532538A - 統合型灌流装置 - Google Patents
統合型灌流装置 Download PDFInfo
- Publication number
- JP2013532538A JP2013532538A JP2013521207A JP2013521207A JP2013532538A JP 2013532538 A JP2013532538 A JP 2013532538A JP 2013521207 A JP2013521207 A JP 2013521207A JP 2013521207 A JP2013521207 A JP 2013521207A JP 2013532538 A JP2013532538 A JP 2013532538A
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- JP
- Japan
- Prior art keywords
- blood
- perfusion device
- integrated
- integrated perfusion
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Images
Classifications
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- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
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- A61M1/267—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes and internal elements which are moving used for pumping
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
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- A61M2240/00—Specially adapted for neonatal use
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Mechanical Engineering (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medical Informatics (AREA)
- Human Computer Interaction (AREA)
- Pulmonology (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1012521.9A GB201012521D0 (en) | 2010-07-27 | 2010-07-27 | Integrated perfusion system |
| GB1012521.9 | 2010-07-27 | ||
| PCT/GB2011/001118 WO2012013925A2 (en) | 2010-07-27 | 2011-07-26 | Integrated perfusion device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013532538A true JP2013532538A (ja) | 2013-08-19 |
| JP2013532538A5 JP2013532538A5 (enExample) | 2014-09-11 |
Family
ID=42752802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013521207A Pending JP2013532538A (ja) | 2010-07-27 | 2011-07-26 | 統合型灌流装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9408959B2 (enExample) |
| EP (1) | EP2598185B1 (enExample) |
| JP (1) | JP2013532538A (enExample) |
| AU (1) | AU2011284543A1 (enExample) |
| GB (2) | GB201012521D0 (enExample) |
| WO (1) | WO2012013925A2 (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016103790A1 (ja) * | 2014-12-25 | 2016-06-30 | テルモ株式会社 | 体外循環管理装置及びこれを有する体外循環装置 |
| JP2019524285A (ja) * | 2016-08-09 | 2019-09-05 | ゼニオス アーゲー | 筐体壁を有する酸素供給器 |
| JP2019527587A (ja) * | 2016-08-08 | 2019-10-03 | ゼニオス アーゲー | 加熱要素を備える酸素付加装置 |
| JP2020143027A (ja) * | 2019-03-08 | 2020-09-10 | 株式会社Screenホールディングス | 灌流装置 |
| JP2022546625A (ja) * | 2019-09-10 | 2022-11-04 | フレセニウス メディカル ケア ホールディングス インコーポレーテッド | 透析流体のインライン加熱 |
| JP2023519653A (ja) * | 2020-03-31 | 2023-05-12 | ゾール サーキュレイション インコーポレイテッド | 患者パラメータフィードバックに基づいて過飽和酸素療法を制御するためのシステムおよび方法 |
| JP2023525463A (ja) * | 2020-04-07 | 2023-06-16 | ジーアイエス ベンチャーズ インコーポレイテッド | 障害または外傷患者に静脈血の短期的緊急酸素化を提供するためのi.v.流体への溶存酸素の注入 |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011016508A1 (de) | 2011-04-08 | 2012-10-11 | Sorin Group Deutschland Gmbh | Temperiervorrichtung für den Einsatz in fluidbasierten Hyper-/Hypothermie-Systemen |
| DE102013008159A1 (de) | 2012-05-14 | 2013-11-14 | Thoratec Corporation | Mantelsystem für Katheterpumpe |
| ITPD20120189A1 (it) * | 2012-06-11 | 2013-12-12 | Elvido Medical Technology Srl | Apparecchiatura per il trattamento termico di un fluido per alimentare o un catetere centrale venoso o altri dispositivi extracorporei per trattamenti termici di pazienti |
| EP2698176B1 (en) | 2012-08-13 | 2017-03-15 | Sorin Group Deutschland GmbH | Method and apparatus for disinfection of a temperature control device for human body temperature control during extracorporeal circulation |
| EP2698177B1 (en) | 2012-08-13 | 2015-01-14 | Sorin Group Deutschland GmbH | Method for controlling a disinfection status of a temperature control device and temperature control device for human body temperature control during extracorporeal circulation |
| ES2478695B1 (es) * | 2012-12-20 | 2015-04-28 | Servicio Andaluz De Salud | Dispositivo para inducir hipotermia terapéutica |
| EP2982396B1 (en) * | 2013-04-01 | 2017-11-29 | Terumo Kabushiki Kaisha | Circulation device |
| US10363349B2 (en) * | 2014-04-15 | 2019-07-30 | Tc1 Llp | Heart pump providing adjustable outflow |
| US10293095B2 (en) * | 2014-07-11 | 2019-05-21 | Jerry Chris Elliott | Hyperoxygenation/hyperthermia treatment apparatus |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62691Y2 (enExample) * | 1980-10-28 | 1987-01-09 | ||
| JPH03131266A (ja) * | 1989-10-16 | 1991-06-04 | Terumo Corp | 医療用ポンプ装置 |
| JPH07116249A (ja) * | 1993-10-20 | 1995-05-09 | A X:Kk | 人工心肺装置 |
| JPH11502133A (ja) * | 1995-03-10 | 1999-02-23 | エントレメッド インコーポレイテッド | フローエレクトロポレーションチャンバー及び方法 |
| JP2000005302A (ja) * | 1998-06-26 | 2000-01-11 | Dainippon Ink & Chem Inc | ガス交換方法 |
| JP2001231853A (ja) * | 2000-02-21 | 2001-08-28 | Nikkiso Co Ltd | 医療用液体の熱交換用容器及び温度調節装置 |
| JP2006296452A (ja) * | 2005-04-15 | 2006-11-02 | Kawasumi Lab Inc | ペルチエユニット及びペルチエユニットを含む医療機器並びに人工心肺装置 |
| JP2007516007A (ja) * | 2003-09-17 | 2007-06-21 | ザィサン バグ | Pcbによって製造されたヒーターを有する加温装置 |
| US20080031773A1 (en) * | 2006-08-03 | 2008-02-07 | Terumo Cardiovascular Systems Corporation | Thermoelectric temperature control for extracorporeal blood circuit |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4306018A (en) * | 1980-06-26 | 1981-12-15 | The Board Of Regents Of The University Of Nebraska | Method of gas-heat exchange |
| US4490331A (en) | 1982-02-12 | 1984-12-25 | Steg Jr Robert F | Extracorporeal blood processing system |
| JPH0450395Y2 (enExample) | 1985-06-18 | 1992-11-27 | ||
| US4722829A (en) | 1986-03-24 | 1988-02-02 | Giter Gregory D | Blood oxygenator |
| US5069661A (en) | 1988-05-18 | 1991-12-03 | Brigham And Women's Hospital | Circulatory support system |
| US5713730A (en) * | 1992-09-04 | 1998-02-03 | Kyocera Corporation | Ceramic pivot bearing arrangement for a sealless blood pump |
| JPH06237992A (ja) | 1993-02-15 | 1994-08-30 | Terumo Corp | 熱およびガス交換器 |
| US6074605A (en) | 1995-03-10 | 2000-06-13 | Entremed, Inc. | Flow electroporation chamber and method |
| US5643794A (en) * | 1995-06-07 | 1997-07-01 | W.R. Grace & Co.-Conn. | Apparatus for bioprocessing a circulating fluid |
| US5770149A (en) | 1995-10-31 | 1998-06-23 | Baxter International | Extracorporeal blood oxygenation system having integrated blood pump, heat exchanger and membrane oxygenator |
| US6045752A (en) | 1996-03-18 | 2000-04-04 | Medtronic, Inc. | Blood oxygenator with waterless heat exchanger |
| US6117390A (en) | 1998-03-27 | 2000-09-12 | Medtronic, Inc. | Compact blood oxygenator utilizing longitudinally interspersed transversely extending heat exchanger conduits and oxygenator fibers |
| US6113782A (en) | 1998-07-28 | 2000-09-05 | Terumo Cardiovascular Systems Corporation | Potting of tubular bundles in housing |
| US6428747B1 (en) | 1998-12-30 | 2002-08-06 | Cardiovention, Inc. | Integrated extracorporeal blood oxygenator, pump and heat exchanger system |
| WO2001082999A2 (en) * | 2000-04-27 | 2001-11-08 | Medtronic, Inc. | Cardiorespiratory system with improved biocompatible coating |
| SE0002100D0 (sv) | 2000-06-05 | 2000-06-05 | Jostra Ab | Cerebral temperering |
| US6739138B2 (en) * | 2001-11-26 | 2004-05-25 | Innovations Inc. | Thermoelectric modules and a heating and cooling apparatus incorporating same |
| US6755026B2 (en) * | 2002-10-24 | 2004-06-29 | Tech Medical Devices Inc. | Thermoelectric system to directly regulate the temperature of intravenous solutions and bodily fluids |
| AU2003290653A1 (en) * | 2002-11-07 | 2004-06-03 | Isao, Nemoto | Artificial heart-lung apparatus |
| ITMI20030647A1 (it) | 2003-04-01 | 2004-10-02 | Dideco Spa | Dispositivo per il trattamento di sangue in circolazione extracorporea |
| US7022284B2 (en) | 2003-05-09 | 2006-04-04 | Cardiovention, Inc. | Extracorporeal blood handling system with integrated heat exchanger |
| US20070249888A1 (en) | 2004-09-13 | 2007-10-25 | Zhongjun Wu | Blood Pump-Oxygenator System |
| ES2440477T3 (es) | 2005-12-15 | 2014-01-29 | Laboratorios Cair España, Sl | Dispositivo para ajustar la temperatura de un fluido fisiológico |
| DE102006020494A1 (de) * | 2006-04-21 | 2007-10-25 | Novalung Gmbh | Künstliches Lungensystem und dessen Verwendung |
| EP1930034B1 (en) | 2006-12-07 | 2012-11-14 | Thoratec LLC | An integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a method of de-bubbling and priming an extracorporeal life support system |
| JP2009160265A (ja) | 2008-01-08 | 2009-07-23 | Terumo Corp | 人工心肺ユニットおよび人工心肺装置 |
-
2010
- 2010-07-27 GB GBGB1012521.9A patent/GB201012521D0/en not_active Ceased
-
2011
- 2011-07-26 US US13/811,861 patent/US9408959B2/en not_active Expired - Fee Related
- 2011-07-26 EP EP11745998.2A patent/EP2598185B1/en not_active Not-in-force
- 2011-07-26 AU AU2011284543A patent/AU2011284543A1/en not_active Abandoned
- 2011-07-26 GB GB1213610.7A patent/GB2489188B/en not_active Expired - Fee Related
- 2011-07-26 JP JP2013521207A patent/JP2013532538A/ja active Pending
- 2011-07-26 WO PCT/GB2011/001118 patent/WO2012013925A2/en not_active Ceased
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62691Y2 (enExample) * | 1980-10-28 | 1987-01-09 | ||
| JPH03131266A (ja) * | 1989-10-16 | 1991-06-04 | Terumo Corp | 医療用ポンプ装置 |
| JPH07116249A (ja) * | 1993-10-20 | 1995-05-09 | A X:Kk | 人工心肺装置 |
| JPH11502133A (ja) * | 1995-03-10 | 1999-02-23 | エントレメッド インコーポレイテッド | フローエレクトロポレーションチャンバー及び方法 |
| JP2000005302A (ja) * | 1998-06-26 | 2000-01-11 | Dainippon Ink & Chem Inc | ガス交換方法 |
| JP2001231853A (ja) * | 2000-02-21 | 2001-08-28 | Nikkiso Co Ltd | 医療用液体の熱交換用容器及び温度調節装置 |
| JP2007516007A (ja) * | 2003-09-17 | 2007-06-21 | ザィサン バグ | Pcbによって製造されたヒーターを有する加温装置 |
| JP2006296452A (ja) * | 2005-04-15 | 2006-11-02 | Kawasumi Lab Inc | ペルチエユニット及びペルチエユニットを含む医療機器並びに人工心肺装置 |
| US20080031773A1 (en) * | 2006-08-03 | 2008-02-07 | Terumo Cardiovascular Systems Corporation | Thermoelectric temperature control for extracorporeal blood circuit |
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| KR20170099901A (ko) * | 2014-12-25 | 2017-09-01 | 테루모 가부시키가이샤 | 체외 순환 관리 장치, 및 이를 갖는 체외 순환 장치 |
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| JP2022546625A (ja) * | 2019-09-10 | 2022-11-04 | フレセニウス メディカル ケア ホールディングス インコーポレーテッド | 透析流体のインライン加熱 |
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Also Published As
| Publication number | Publication date |
|---|---|
| GB201213610D0 (en) | 2012-09-12 |
| WO2012013925A3 (en) | 2012-05-10 |
| US9408959B2 (en) | 2016-08-09 |
| AU2011284543A1 (en) | 2013-02-07 |
| WO2012013925A2 (en) | 2012-02-02 |
| EP2598185A2 (en) | 2013-06-05 |
| EP2598185B1 (en) | 2016-08-17 |
| GB201012521D0 (en) | 2010-09-08 |
| GB2489188B (en) | 2013-08-14 |
| US20130280692A1 (en) | 2013-10-24 |
| GB2489188A (en) | 2012-09-19 |
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