JP2013529634A - 治療用口腔用組成物 - Google Patents
治療用口腔用組成物 Download PDFInfo
- Publication number
- JP2013529634A JP2013529634A JP2013516555A JP2013516555A JP2013529634A JP 2013529634 A JP2013529634 A JP 2013529634A JP 2013516555 A JP2013516555 A JP 2013516555A JP 2013516555 A JP2013516555 A JP 2013516555A JP 2013529634 A JP2013529634 A JP 2013529634A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- oral
- salts
- acid
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8164—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers, e.g. poly (methyl vinyl ether-co-maleic anhydride)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
- A61K8/8182—Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
歯の3つの無機化組織は、エナメル質、セメント質および象牙質である。ヒトの歯においては、エナメル質が歯冠部の象牙質を覆い、これに対して、セメント質が歯根部の象牙質を覆う。一方、象牙質は、象牙質に血管および神経の支持体を提供する歯の髄質を包み込む。エナメル質およびセメント質とは異なり、象牙質には、無数の細管が横行する。これらの細管の壁が象牙質の石灰化マトリックスから構成され、細管空間が、歯髄組織液および血漿に由来する流体(歯液)により満たされる。マトリックスの無機質が主に、中性およびアルカリ性のpHでは溶解しにくく、pHが徐々に酸性化するにつれ、徐々に溶解しやくなるリン酸カルシウムの塩、すなわち、ヒドロキシアパタイトから構成される。
下記の定義および非限定的な指針は、本明細書中に示される本発明の説明を検討する際には考慮されなければならない。本明細書中で使用される見出し(例えば、「背景」および「概要」など)および小見出し(例えば、「組成物」および「方法」など)は、本発明の開示に含まれる論題の一般的な構成のためにだけ意図され、本発明またはそのいずれかの態様の開示を限定するためには意図されない。特に、「背景」において開示される主題は、本発明の範囲に含まれる技術の様々な態様を含むかもしれず、また、先行技術の列挙を構成しないかもしれない。「概要」において開示される主題は、本発明またはそのいずれかの実施形態の範囲全体の網羅的または完全な開示ではない。特定の有用性を有するとしての、(例えば、「活性」成分または「キャリア」成分であるとしての)本明細書の節における材料の分類または議論は便宜のためになされており、そのため、この材料がいずれかの所与の組成物において使用されるとき、この材料は本明細書中におけるその分類に従って必然的または単独で機能しなければならないという推論を引き出してはならない。
実施例1
本明細書中に記載される組成物の脱感作性を試験するために、いくつかの口腔用組成物を、米国特許第5,589,159号に記載される方法を使用して試験した(その開示がその全体において参照によって本明細書中に組み込まれる)。この方法は材料の水力学的コンダクタンスを測定する(これにより、象牙質細管における流体の流れにおける低下と相関する流体の流れにおける客観的な低下がもたらされる)。この方法では、う蝕部および修復部がない無傷のヒト大臼歯が、薄い切片、すなわち、ディスク(約0.4mm〜約0.8mmの厚さ)を形成するために冶金の鋸を用いて歯の長軸に対して直角に切片化される。象牙質を含有し、エナメル質を含まない切片を試験のために選択し、その後、クエン酸溶液でエッチングして、スメア層を除いた。それぞれのディスクを、J. Dent. Research、57:187 (1978)に記載されるスプリットチャンバー型デバイスに取り付けた(このデバイスは、組織培養液を含有する加圧流体リザーバーにつながれる、漏れのない特別なチャンバーである)。加圧窒素ガスおよび二酸化炭素ガスの混合物を使用することによって、流体を生理学的pHにすることができる。正確性をさらに確保するために、ディスクを、口腔内条件に近づけるために人工唾液(リン酸塩緩衝液生理的食塩水、PBS)により湿らした。装置には、流れセンサー(FLODEC、DeMarco Engineering SA、Geneva)に取り付けられるガラスキャピラリー管が含まれる。気泡がガラスキャピラリー管の中に注入される。気泡の移動を時間の関数として測定することによって、象牙質ディスクを通過する流体の流れを測定することができる。流体の流れは象牙質の透過性と同等である。
Claims (20)
- 遊離形態または塩形態での少なくとも1つのアルギニン化合物と、少なくとも1つの粘膜付着性ポリマーと、ピロリン酸塩化合物、亜鉛塩、カリウム塩、ストロンチウム塩およびそれらの混合物からなる群から選択される少なくとも1つの成分とを含むオーラルケア組成物。
- 前記アルギニン化合物がD形態またはL形態で存在するか、あるいは、ラウロイル硫酸との塩として存在する、請求項1に記載の組成物。
- 前記アルギニン化合物が0.1重量%〜20重量%の範囲における量で存在する、請求項1に記載の組成物。
- 前記粘膜付着性ポリマーが、ポリビニルメチルエーテル/無水マレイン酸(PVME/MA)コポリマー、アクリル酸/メチルアクリラート/スチレン/2−アクリロアミド−2−メチルプロパンスホン(sufonic)酸コポリマー、ポリ(ビニルピロリドン)(PVP)、カルボキシメチルセルロース(CMC)、キサンタンおよびそれらの混合物からなる群から選択される、請求項1に記載の組成物。
- 前記粘膜付着性ポリマーがポリビニルメチルエーテル/無水マレイン酸(PVME/MA)コポリマーである、請求項4に記載の組成物。
- 前記粘膜付着性ポリマーが0.1重量%〜20重量%の範囲における量で存在する、請求項1に記載の組成物。
- さらには抗菌剤を含む、請求項1に記載の組成物。
- 前記ピロリン酸塩が、ピロリン酸二水素二ナトリウム(Na2H2P2O7)、ピロリン酸四ナトリウム(Na4P2O7)、ピロリン酸四カリウム(K4P2O7)およびそれらの混合物からなる群から選択される、請求項1に記載の組成物。
- マウスウォッシュ、歯用ゲル、歯周用ゲル、および、歯表面塗布のために好適な液体からなる群から選択される形態である、請求項1に記載の組成物。
- マウスウォッシュである、請求項9に記載の組成物。
- 透水試験を使用して測定されるとき、50%を超える流動低下を有する、請求項1に記載の組成物。
- 歯の過敏性を低下させること、虫歯形成の低下または阻害をもたらすこと、歯の脱灰の低下または阻害をもたらし、また、歯の再石灰化の促進をもたらすこと、歯肉炎の軽減または阻害をもたらすこと、口腔における微生物バイオフィルムの形成を阻害すること、歯垢の蓄積を低下させること、口内乾燥を処置すること、歯の侵食を軽減すること、エナメル質を侵食性攻撃後において保護すること、ならびに、歯の清浄化および/またはホワイトニングをもたらし、また、口腔の清浄化をもたらすことからなる群から選択される1つまたは複数のことを行う方法であって、
a)遊離形態または塩形態でのアルギニンと、粘膜付着性ポリマーと、ピロリン酸塩化合物、亜鉛塩、カリウム塩、ストロンチウム塩およびそれらの混合物からなる群から選択される少なくとも1つの成分とを含む口腔用組成物を調製すること、および
b)前記口腔用組成物を口腔に適用すること
を含む方法。 - 前記組成物が、少なくとも2週間にわたって少なくとも1日に1回、口腔に適用される、請求項12に記載の方法。
- 前記アルギニン化合物がD形態またはL形態で存在するか、あるいは、ラウロイル硫酸との塩として存在する、請求項12に記載の方法。
- 前記アルギニン化合物が0.1重量%〜20重量%の範囲における量で存在する、請求項12に記載の方法。
- 前記粘膜付着性ポリマーが、ポリビニルメチルエーテル/無水マレイン酸(PVME/MA)コポリマー、アクリル酸/メチルアクリラート/スチレン/2−アクリロアミド−2−メチルプロパンスホン(sufonic)酸コポリマー、ポリ(ビニルピロリドン)(PVP)、カルボキシメチルセルロース(CMC)、キサンタンおよびそれらの混合物からなる群から選択される、請求項12に記載の方法。
- 前記粘膜付着性ポリマーがポリビニルメチルエーテル/無水マレイン酸(PVME/MA)コポリマーである、請求項16に記載の方法。
- 前記粘膜付着性ポリマーが0.1重量%〜20重量%の範囲における量で存在する、請求項12に記載の方法。
- さらには抗菌剤を含む、請求項12に記載の方法。
- 包装材と、請求項1に記載される組成物とを含む物品であって、前記包装材は、前記口腔用組成物が象牙質過敏性の遅延または防止において効果的であることを示す表示を含む、物品。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2010/039677 WO2011162756A1 (en) | 2010-06-23 | 2010-06-23 | Therapeutic oral composition |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013529634A true JP2013529634A (ja) | 2013-07-22 |
JP5723001B2 JP5723001B2 (ja) | 2015-05-27 |
Family
ID=43877170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013516555A Expired - Fee Related JP5723001B2 (ja) | 2010-06-23 | 2010-06-23 | 治療用口腔用組成物 |
Country Status (16)
Country | Link |
---|---|
US (2) | US9579269B2 (ja) |
EP (1) | EP2585025B2 (ja) |
JP (1) | JP5723001B2 (ja) |
CN (1) | CN102946841A (ja) |
AU (1) | AU2010356102B2 (ja) |
BR (1) | BR112012030037B1 (ja) |
CA (1) | CA2800475C (ja) |
ES (1) | ES2529216T3 (ja) |
HK (1) | HK1183802A1 (ja) |
MX (1) | MX2012013955A (ja) |
PL (1) | PL2585025T3 (ja) |
RU (1) | RU2535088C2 (ja) |
SG (1) | SG185631A1 (ja) |
TW (1) | TWI504415B (ja) |
WO (1) | WO2011162756A1 (ja) |
ZA (1) | ZA201209156B (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017104664A1 (ja) * | 2015-12-14 | 2017-06-22 | 花王株式会社 | 液体口腔用組成物 |
JP2020535166A (ja) * | 2017-09-29 | 2020-12-03 | スリーエム イノベイティブ プロパティズ カンパニー | 水性口腔ケアフッ化物処置組成物、及び方法 |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2654671B1 (en) | 2010-12-20 | 2019-02-20 | Colgate-Palmolive Company | Non-aqueous oral care composition containing dental occlusion actives |
WO2012087279A1 (en) | 2010-12-20 | 2012-06-28 | Colgate-Palmolive Company | Gelatin encapsulated oral care composition containing dental occlusion actives, hydrophobic viscosity modifier and oil carrier |
RU2601681C2 (ru) * | 2011-06-01 | 2016-11-10 | ДДС Мартин Н. ГОРМАН | Зубное устройство |
EP2919750A4 (en) * | 2012-11-15 | 2016-05-11 | Isp Investments Inc | ORAL CARE COMPOSITIONS FOR THE TREATMENT OF SENSITIVE TEETH |
CN104822362A (zh) * | 2012-12-05 | 2015-08-05 | 高露洁-棕榄公司 | 氟化物稳定的含锌组合物 |
AU2012397149B2 (en) * | 2012-12-18 | 2015-11-05 | Colgate-Palmolive Company | Stable metal ion containing compositions |
WO2014159659A1 (en) * | 2013-03-12 | 2014-10-02 | Stein Emily A | Dental composition comprising chelator and base |
WO2015048146A1 (en) | 2013-09-24 | 2015-04-02 | The Regents Of The University Of Michigan | Compositions and method for destabilizing, altering, and dispersing biofilms |
EP3076921B1 (en) * | 2013-12-02 | 2020-03-04 | Colgate-Palmolive Company | Oral care zinc compositions |
BR112016012151B1 (pt) | 2013-12-03 | 2020-03-10 | Colgate-Palmolive Company | Composição dentifrícia e uso |
WO2015094254A1 (en) * | 2013-12-19 | 2015-06-25 | Colgate-Palmolive Company | Anti-malodor oral care composition |
CN104721226B (zh) | 2013-12-19 | 2019-12-24 | 高露洁-棕榄公司 | 口腔护理组合物 |
CN104721225A (zh) * | 2013-12-19 | 2015-06-24 | 高露洁-棕榄公司 | 口腔护理组合物 |
CN104721063B (zh) | 2013-12-19 | 2018-05-08 | 高露洁-棕榄公司 | 包含氧化锌和柠檬酸锌的洁齿剂组合物 |
MX368520B (es) * | 2014-10-15 | 2019-10-07 | Colgate Palmolive Co | Composiciones para el cuidado oral que comprende zinc, arginina y serina. |
US10772908B2 (en) | 2014-12-10 | 2020-09-15 | Elevate Oral Care, Llc | Composition for the relief of dry mouth |
AU2014415217B2 (en) | 2014-12-26 | 2018-11-29 | Colgate-Palmolive Company | Zinc phosphate complex |
EP3223773B1 (en) * | 2014-12-26 | 2021-09-22 | Colgate-Palmolive Company | Oral care compositions and methods of use |
CA2971576A1 (en) | 2014-12-26 | 2016-06-30 | Colgate-Palmolive Company | Zinc phosphate complex |
RU2681525C2 (ru) | 2014-12-26 | 2019-03-07 | Колгейт-Палмолив Компани | Композиции для личной гигиены с фосфатом цинка в качестве активного вещества |
RU2692066C2 (ru) | 2014-12-26 | 2019-06-20 | Колгейт-Палмолив Компани | Комплекс фосфата цинка |
KR102076268B1 (ko) * | 2015-04-17 | 2020-02-11 | 주식회사 엘지생활건강 | 구강용 조성물 |
WO2016167600A1 (ko) * | 2015-04-17 | 2016-10-20 | 주식회사 엘지생활건강 | 구강용 조성물 |
RU2677072C1 (ru) * | 2015-07-01 | 2019-01-15 | Колгейт-Палмолив Компани | Композиции для ухода за полостью рта и способы их применения |
WO2017044469A1 (en) * | 2015-09-10 | 2017-03-16 | The University Of Florida Research Foundation, Inc. | Arginine-containing restorative dental materials and methods of preventing and controlling caries associated with dental work |
CA2998139C (en) | 2015-09-11 | 2021-07-27 | Wm. Wrigley Jr. Company | Synergistic antibacterial effects of magnolia bark extract and l-arginine, n-lauroyl ethyl ester on plaque biofilm |
CN115350117A (zh) * | 2016-11-08 | 2022-11-18 | 高露洁-棕榄公司 | 口腔护理组合物 |
EP3522864A1 (en) * | 2016-11-08 | 2019-08-14 | Colgate-Palmolive Company | Oral care compositions |
US10813855B2 (en) * | 2016-12-21 | 2020-10-27 | Oral Health Innovations, LLC | Oral care products and methods |
US10058493B2 (en) | 2016-12-21 | 2018-08-28 | Colgate-Palmolive Company | Oral care compositions and methods of use |
WO2018197160A1 (en) | 2017-04-27 | 2018-11-01 | Unilever N.V. | Oral care composition |
WO2018204795A1 (en) * | 2017-05-04 | 2018-11-08 | Phoenix Dental, Inc. | Dental composition and method |
US10912731B2 (en) | 2017-08-04 | 2021-02-09 | Colgate-Palmolive Company | Biphasic oral care compositions |
CN110944721B (zh) * | 2017-08-04 | 2023-12-26 | 高露洁-棕榄公司 | 双相口腔护理组合物 |
US11497694B2 (en) * | 2017-12-13 | 2022-11-15 | Colgate-Palmolive Company | Oral care compositions |
TWI686194B (zh) * | 2018-02-27 | 2020-03-01 | 林蕭水銀 | 廣效抗菌及抗癌之醫藥組合物及其用途 |
MX2021004167A (es) * | 2018-10-16 | 2021-06-08 | Colgate Palmolive Co | Composiciones y metodos para el cuidado bucal. |
AU2019416047B2 (en) * | 2018-12-26 | 2023-01-05 | Colgate-Palmolive Company | Specific co-aggregation inhibition by arginine |
CN113329730A (zh) * | 2019-02-01 | 2021-08-31 | 高露洁-棕榄公司 | 用于口腔护理组合物的防腐剂系统 |
RU2741992C2 (ru) * | 2019-04-12 | 2021-02-01 | Колгейт-Палмолив Компани | Композиция для ухода за полостью рта, устраняющая неприятный запах |
EP3996724A1 (en) * | 2019-07-12 | 2022-05-18 | Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis | Oral disodium pyrophosphate for use in reducing calcification |
US20210298996A1 (en) * | 2020-03-27 | 2021-09-30 | Colgate-Palmolive Company | Oral Care Composition and Methods of Use |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03128316A (ja) * | 1989-06-21 | 1991-05-31 | Yissum Res Dev Co Of Hebrew Univ Of Jerusalem | 液体重合体組成物及びその使用方法 |
JPH0627137A (ja) * | 1992-07-08 | 1994-02-04 | Murata Mfg Co Ltd | 加速度センサ |
WO2009099455A1 (en) * | 2008-02-08 | 2009-08-13 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
WO2009152507A2 (en) * | 2008-06-13 | 2009-12-17 | Colgate-Palmolive Company | Oral compositions and uses thereof |
Family Cites Families (136)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
US3678154A (en) | 1968-07-01 | 1972-07-18 | Procter & Gamble | Oral compositions for calculus retardation |
US3535421A (en) | 1968-07-11 | 1970-10-20 | Procter & Gamble | Oral compositions for calculus retardation |
US4154815A (en) | 1970-04-01 | 1979-05-15 | Lever Brothers Company | Zinc and enzyme toothpowder dentifrice |
US3683006A (en) | 1970-09-09 | 1972-08-08 | Syntex Corp | Cyclodecapentaene compounds |
US3696191A (en) | 1970-11-10 | 1972-10-03 | Monsanto Co | Dental creams containing enzymes |
US3943241A (en) | 1971-08-30 | 1976-03-09 | General Mills, Inc. | Cariostatic composition |
US3932608A (en) | 1971-08-30 | 1976-01-13 | General Mills, Inc. | Food composition |
US4058595A (en) | 1971-10-13 | 1977-11-15 | Colgate-Palmolive Company | Stabilized toothpastes containing an enzyme |
US3932605A (en) | 1972-06-12 | 1976-01-13 | Jaroslav Vit | Dental treatment |
US3988434A (en) | 1972-08-07 | 1976-10-26 | Schole Murray L | Dental preparation |
US3959458A (en) | 1973-02-09 | 1976-05-25 | The Procter & Gamble Company | Oral compositions for calculus retardation |
US3937807A (en) | 1973-03-06 | 1976-02-10 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
US4025616A (en) | 1973-03-06 | 1977-05-24 | The Procter & Gamble Company | Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies |
US3862307A (en) | 1973-04-09 | 1975-01-21 | Procter & Gamble | Dentifrices containing a cationic therapeutic agent and improved silica abrasive |
US4100269A (en) | 1973-06-28 | 1978-07-11 | Lever Brothers Company | Anticalculus dentifrice |
US4022880A (en) | 1973-09-26 | 1977-05-10 | Lever Brothers Company | Anticalculus composition |
US3925543A (en) | 1973-11-01 | 1975-12-09 | Colgate Palmolive Co | Antibacterial oral compositions containing preservative-antioxidants |
US3991177A (en) | 1973-11-27 | 1976-11-09 | Colgate-Palmolive Company | Oral compositions containing dextranase |
US4011309A (en) | 1975-01-20 | 1977-03-08 | Marion Laboratories, Inc. | Dentifrice composition and method for desensitizing sensitive teeth |
US4051234A (en) | 1975-06-06 | 1977-09-27 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
US4064138A (en) | 1975-11-12 | 1977-12-20 | General Mills, Inc. | Amino acid derivatives |
NL180807C (nl) | 1975-12-26 | 1987-05-04 | Morishita Jintan Co | Inrichting voor het vervaardigen van naadloze, met materiaal gevulde capsules. |
US4138477A (en) | 1976-05-28 | 1979-02-06 | Colgate Palmolive Company | Composition to control mouth odor |
USRE31181E (en) | 1976-06-18 | 1983-03-15 | Means and method for improving natural defenses against caries | |
ZA773318B (en) | 1976-06-18 | 1978-04-26 | I Kleinberg | Means and method for improving natural defenses against caries |
US4042680A (en) | 1976-08-02 | 1977-08-16 | Indiana University Foundation | Anticariogenic maloaluminate complexes |
US4108981A (en) | 1976-08-02 | 1978-08-22 | Indiana University Foundation | Alkaline oral compositions comprising aluminum and a carboxylic acid |
US4108979A (en) | 1976-08-02 | 1978-08-22 | Indiana University Foundation | Dentifrice preparations comprising aluminum and a compatible abrasive |
US4146607A (en) | 1977-11-07 | 1979-03-27 | Lever Brothers Company | Synergistic anti-plaque mixture with tetradecylamine plus aluminum and/or zinc |
US4160821A (en) | 1978-02-27 | 1979-07-10 | Johnson & Johnson | Treatment for gingivitis |
US4213961A (en) | 1978-03-23 | 1980-07-22 | Beecham, Inc. | Oral compositions |
GB1573727A (en) | 1978-05-19 | 1980-08-28 | Colgate Palmolive Co | Dentifrices |
US4216961A (en) | 1978-08-04 | 1980-08-12 | Mcquillan Mary J | Table baseball apparatus |
US4177258A (en) | 1978-10-13 | 1979-12-04 | Colgate Palmolive Company | Dentifrice for dental remineralization |
US4225579A (en) | 1979-02-27 | 1980-09-30 | Israel Kleinberg | Means and method for improving defenses against caries |
US4340583A (en) | 1979-05-23 | 1982-07-20 | J. M. Huber Corporation | High fluoride compatibility dentifrice abrasives and compositions |
US4339432A (en) | 1979-06-20 | 1982-07-13 | Lever Brothers Company | Oral mouthwash containing zinc and glycine |
US4226851A (en) | 1979-07-11 | 1980-10-07 | Sompayrac Hewitt A | Stable dental composition containing hydrogen peroxide |
US4269822A (en) | 1979-07-20 | 1981-05-26 | Laclede Professional Products, Inc. | Antiseptic dentifrice |
JPS5835965B2 (ja) | 1979-07-31 | 1983-08-05 | ライオン株式会社 | 口腔用組成物 |
JPS5846483B2 (ja) | 1979-09-20 | 1983-10-17 | ライオン株式会社 | 口腔用組成物 |
US4292304A (en) | 1980-09-30 | 1981-09-29 | Barels Ronald R | Oil based dentifrice |
US4355022A (en) | 1981-07-01 | 1982-10-19 | Interon, Inc. | Method of dental treatment |
US4606912A (en) | 1981-07-22 | 1986-08-19 | Caries Research Group Of Rochester, Inc. | Method of making a clear, stable aqueous mouthwash solution and the solution made by that method for the enhancement of cells of the oral cavity and the remineralization of teeth |
US4532124A (en) | 1981-08-19 | 1985-07-30 | Development Finance Corporation Of New Zealand | Dental rinse |
JPS58118509A (ja) | 1981-12-29 | 1983-07-14 | Lion Corp | 口腔用組成物 |
US4885155A (en) | 1982-06-22 | 1989-12-05 | The Procter & Gamble Company | Anticalculus compositions using pyrophosphate salt |
US4422985A (en) | 1982-09-24 | 1983-12-27 | Morishita Jintan Co., Ltd. | Method and apparatus for encapsulation of a liquid or meltable solid material |
JPS6092208A (ja) | 1983-10-25 | 1985-05-23 | Kao Corp | 塩化ナトリウム含有歯磨組成物 |
US4521551A (en) | 1983-12-02 | 1985-06-04 | Block Drug Company, Inc. | Denture fixative composition containing partially neutralized copolymers of maleic acid or anhydride and alkyl vinyl ethers which are optionally partially crosslinked |
US4725576A (en) | 1983-12-29 | 1988-02-16 | Research Foundation Of State University Of New York | Fungicidal polypeptide compositions containing L-histidine and methods for use therefore |
US4528181A (en) | 1984-02-01 | 1985-07-09 | Colgate-Palmolive Company | Dentifrice containing dual sources of fluoride |
US4631185A (en) | 1984-03-13 | 1986-12-23 | The Trustees Of Columbia University In The City Of New York | Method of desensitizing hypersensitive dentin employing compositions containing potassium salts |
US5334617A (en) | 1984-03-19 | 1994-08-02 | The Rockefeller University | Amino acids useful as inhibitors of the advanced glycosylation of proteins |
GB8411731D0 (en) | 1984-05-09 | 1984-06-13 | Unilever Plc | Oral compositions |
US5000939A (en) | 1984-06-12 | 1991-03-19 | Colgate-Palmolive Company | Dentifrice containing stabilized enzyme |
JPH0742219B2 (ja) | 1984-07-26 | 1995-05-10 | ライオン株式会社 | 口腔用組成物 |
US4538990A (en) | 1984-09-24 | 1985-09-03 | Medical College Of Ga. Research Institute, Inc. | Method of decreasing the permeability of a dental cavity |
US4623536A (en) | 1985-06-13 | 1986-11-18 | Church & Dwight Co., Inc. | Sodium bicarbonate containing toothpaste |
US4889712A (en) * | 1986-03-20 | 1989-12-26 | Colgate-Palmolive Company | Anticalculus oral composition |
US5188821A (en) | 1987-01-30 | 1993-02-23 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition mouthwash or liquid dentifrice |
US5192531A (en) | 1988-12-29 | 1993-03-09 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
US5192530A (en) | 1987-01-30 | 1993-03-09 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
CH671879A5 (ja) | 1987-02-26 | 1989-10-13 | Nestle Sa | |
US4866161A (en) | 1987-08-24 | 1989-09-12 | University Of South Alabama | Inhibition of tartar deposition by polyanionic/hydrophobic peptides and derivatives thereof which have a clustered block copolymer structure |
US5004597A (en) | 1987-09-14 | 1991-04-02 | The Procter & Gamble Company | Oral compositions comprising stannous flouride and stannous gluconate |
US4898760A (en) | 1987-11-17 | 1990-02-06 | Amesbury Industries, Inc. | Process and apparatus for extruding a low density elastomeric thermoplastic foam |
GB8729564D0 (en) | 1987-12-18 | 1988-02-03 | Unilever Plc | Oral compositions |
US4842847A (en) | 1987-12-21 | 1989-06-27 | The B. F. Goodrich Company | Dental calculus inhibiting compositions |
US5438076A (en) | 1988-05-03 | 1995-08-01 | Perio Products, Ltd. | Liquid polymer composition, and method of use |
US5334375A (en) | 1988-12-29 | 1994-08-02 | Colgate Palmolive Company | Antibacterial antiplaque oral composition |
SU1754104A1 (ru) | 1989-01-05 | 1992-08-15 | Одесский научно-исследовательский институт стоматологии | Зубной порошок |
US5139768A (en) * | 1989-01-31 | 1992-08-18 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Dental composition for hypersensitive teeth |
GB8904182D0 (en) | 1989-02-23 | 1989-04-05 | Glaxo Canada | Pharmaceutical compositions |
GB8922594D0 (en) | 1989-10-06 | 1989-11-22 | Unilever Plc | Oral compositions |
US4992258A (en) * | 1989-10-23 | 1991-02-12 | Colgate-Palmolive Company | Dentrifice composition |
US5197531A (en) | 1990-06-13 | 1993-03-30 | Leybold Aktiengesellschaft | Method of manufacturing directionally solidified castings |
US5096700A (en) | 1990-09-28 | 1992-03-17 | The Procter & Gamble Company | Halogenated aminohexanoates and aminobutyrates antimicrobial agents |
JPH06502141A (ja) * | 1990-10-25 | 1994-03-10 | ザ ブーツ カンパニー ピーエルシー | 口内洗浄剤 |
US5543443A (en) | 1992-01-27 | 1996-08-06 | The Procter & Gamble Company | Denture stabilizing compositions |
DE69204656T2 (de) | 1992-04-28 | 1996-02-08 | Boucherie Nv G B | Verfahren zum Herstellen von Zahnbürsten. |
US5370865A (en) | 1992-05-15 | 1994-12-06 | Kao Corporation | Composition for use in oral cavity |
US5286480A (en) | 1992-06-29 | 1994-02-15 | The Procter & Gamble Company | Use of N-acetylated amino acid complexes in oral care compositions |
CA2127392C (en) | 1993-07-08 | 2008-05-27 | Hideki Sunohara | Process for producing capsule and capsule obtained thereby |
US5531791A (en) | 1993-07-23 | 1996-07-02 | Bioscience Consultants | Composition for repair of defects in osseous tissues, method of making, and prosthesis |
JP3566374B2 (ja) | 1994-02-03 | 2004-09-15 | 花王株式会社 | 口腔用組成物 |
GB2288564B (en) | 1994-04-19 | 1998-09-23 | Boucherie Nv G B | A molding machine for injection molding of tooth brushes |
GB2289236B (en) | 1994-05-09 | 1997-08-06 | Boucherie Nv G B | A brush making machine |
JP3803695B2 (ja) | 1994-11-28 | 2006-08-02 | サンスター株式会社 | 抗菌製剤 |
US5589159A (en) | 1995-04-11 | 1996-12-31 | Block Drug Company Inc. | Dispersible particulate system for desensitizing teeth |
US5561177A (en) | 1995-06-27 | 1996-10-01 | The Block Drug Company | Hydrocarbon free denture adhesive |
AU6515296A (en) | 1995-07-10 | 1997-02-10 | Unilever N.V. | Self-heating dentifrice |
US5571502A (en) | 1995-08-08 | 1996-11-05 | Enamelon Research | Stable single-part compositions and the use thereof for remineralization of lesions in teeth |
US5762911A (en) | 1996-03-05 | 1998-06-09 | The Research Foundation Of State University Of New York | Anti-caries oral compositions |
US6488961B1 (en) | 1996-09-20 | 2002-12-03 | Ethypharm, Inc. | Effervescent granules and methods for their preparation |
US5906811A (en) | 1997-06-27 | 1999-05-25 | Thione International, Inc. | Intra-oral antioxidant preparations |
DK1021204T3 (da) * | 1997-09-26 | 2006-05-08 | Noven Pharma | Bioadhæsive præparater og fremgangsmåder til topisk administration af aktive midler |
US5922346A (en) | 1997-12-01 | 1999-07-13 | Thione International, Inc. | Antioxidant preparation |
FI116642B (fi) | 1998-02-09 | 2006-01-13 | Nokia Corp | Puheparametrien käsittelymenetelmä, puhekoodauksen käsittely-yksikkö ja verkkoelementti |
US5997301A (en) | 1998-10-20 | 1999-12-07 | Linden; Lars Ake | Treatment of tooth surfaces and substances therefor |
US6436370B1 (en) | 1999-06-23 | 2002-08-20 | The Research Foundation Of State University Of New York | Dental anti-hypersensitivity composition and method |
GB2354441A (en) | 1999-08-06 | 2001-03-28 | Mccormack Ltd | Composition for treating dentine hypersensitivity |
GB2354442A (en) * | 1999-09-23 | 2001-03-28 | Allied Bio Corp Ltd | Sterilising block comprising a compound which produces sulphur dioxide on reaction with moisture absorbed by the block, eg a metabisulphite |
JP2004500404A (ja) * | 2000-03-27 | 2004-01-08 | カール − ツァイス − シュティフツング | 生物活性ガラスを含む新規化粧品、ボディケア、洗浄剤および栄養サプリメント組成物および製造方法およびその使用 |
WO2001076549A2 (en) | 2000-04-11 | 2001-10-18 | Gerald Mc Laughlin | Composition and method for whitening teeth |
US6500409B1 (en) | 2000-05-10 | 2002-12-31 | Colgate Palmolive Company | Synergistic antiplaque/antigingivitis oral composition |
US6306435B1 (en) | 2000-06-26 | 2001-10-23 | Yung Shin Pharmaceutical Industrial Co. Ltd. | Oral pharmaceutical preparation embedded in an oily matrix and methods of making the same |
US8283135B2 (en) | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
US20020081360A1 (en) | 2000-12-27 | 2002-06-27 | Andreas Burgard | Salts of L-amino acid having improved taste and their preparation |
CA2452834C (en) | 2001-07-05 | 2010-09-21 | Sunstar Inc. | Oral preparation comprising an abrasive precipitated silica and a sulfosuccinate surfactant |
MXPA04004592A (es) | 2001-11-15 | 2005-06-08 | Miret Lab | Uso de un agente tensioactivo cationico como mejorador de la actividad antimicrobiana en desodorantes y productos para el cuidado bucal. |
RU2275946C2 (ru) | 2001-11-28 | 2006-05-10 | Дзе Проктер Энд Гэмбл Компани | Композиция для чистки зубов (варианты), связывающая система для однофазной композиции для чистки зубов |
DE50211883D1 (de) | 2002-04-30 | 2008-04-24 | Cognis Ip Man Gmbh | Verwendung von Wirkstoffmischungen mit Azelainsäure und Glycyrrhetinsäure als Anti-Aknemittel |
US20040220264A1 (en) | 2003-03-17 | 2004-11-04 | Yu Ruey J | Bioavailability and improved delivery of acidic pharmaceutical drugs |
US7087219B2 (en) | 2003-05-28 | 2006-08-08 | Stanislaw R. Burzynski | Toothpaste containing anticancer agents |
CA2530399C (en) | 2003-06-23 | 2012-08-21 | Colgate-Palmolive Company | Stable dentifrice compositions |
JP4934266B2 (ja) | 2003-07-09 | 2012-05-16 | 花王株式会社 | 口腔用組成物 |
WO2005089703A1 (ja) * | 2004-03-19 | 2005-09-29 | Kao Corporation | 歯磨用組成物 |
WO2006108886A2 (es) * | 2005-04-06 | 2006-10-19 | Fabrica Nacional De Moneda Y Timbre - Real Casa De La Moneda | Papel de seguridad o papel especial que incorpora elementos sinteticos de alta resistencia y procedimiento para la obtencion de dichos papeles |
FR2887886B1 (fr) | 2005-07-01 | 2010-01-08 | Oreal | Polymere cationique neutralise, composition le comprenant et procede de traitement cosmetique |
US20070014740A1 (en) | 2005-07-15 | 2007-01-18 | Colgate-Palmolive Company | Oral compositions having cationic active ingredients |
MX346202B (es) | 2005-11-23 | 2017-03-09 | Colgate Palmolive Co | Metodos y composiciones de sal estañosa y tripolifosfato de sodio para el cuidado oral. |
GB0525369D0 (en) | 2005-12-14 | 2006-01-18 | Ineos Silicas Ltd | Silicas |
US20070258916A1 (en) | 2006-04-14 | 2007-11-08 | Oregon Health & Science University | Oral compositions for treating tooth hypersensitivity |
KR100870232B1 (ko) | 2006-12-07 | 2008-11-24 | 재단법인서울대학교산학협력재단 | 치아용 미백기능성 물질 전달시스템 |
US20090186090A1 (en) | 2007-04-30 | 2009-07-23 | Colgate-Palmolive | Oral Care Composition to Reduce or Eliminate Dental Sensitivity |
US20080267891A1 (en) * | 2007-04-30 | 2008-10-30 | Colgate-Palmolive Company | Oral Care Composition To Reduce Or Eliminate Dental Sensitivity |
WO2009099435A1 (en) | 2008-02-04 | 2009-08-13 | Dakim, Inc. | A method and system for providing adaptive rule based cognitive stimulation to a user |
EP2249785B2 (en) | 2008-02-08 | 2019-09-25 | Colgate-Palmolive Company | Arginine salts and their uses for the treatment of illnesses in the oral cavity |
CN101938981A (zh) | 2008-02-08 | 2011-01-05 | 高露洁-棕榄公司 | 组合物和装置 |
RU2469701C2 (ru) | 2008-02-08 | 2012-12-20 | Колгейт-Палмолив Компани | Продукт для ухода за полостью рта и способы его применения |
EP3345655A1 (en) | 2008-06-04 | 2018-07-11 | The Procter & Gamble Company | Oral care compositions and methods |
US8282298B2 (en) | 2008-06-26 | 2012-10-09 | Colgate-Palmolive Company | Oral care implement |
JP2012509894A (ja) | 2008-11-25 | 2012-04-26 | ザ プロクター アンド ギャンブル カンパニー | 溶融シリカを有する口腔ケア組成物 |
AR076180A1 (es) | 2009-04-01 | 2011-05-26 | Colgate Palmolive Co | Composiciones de uso oral para el tratamiento de la sensibilidad dental y metodos para su produccion y utilizacion |
-
2010
- 2010-06-23 SG SG2012084661A patent/SG185631A1/en unknown
- 2010-06-23 PL PL10727321T patent/PL2585025T3/pl unknown
- 2010-06-23 WO PCT/US2010/039677 patent/WO2011162756A1/en active Application Filing
- 2010-06-23 ES ES10727321.1T patent/ES2529216T3/es active Active
- 2010-06-23 JP JP2013516555A patent/JP5723001B2/ja not_active Expired - Fee Related
- 2010-06-23 RU RU2013102892/15A patent/RU2535088C2/ru not_active IP Right Cessation
- 2010-06-23 BR BR112012030037-7A patent/BR112012030037B1/pt active IP Right Grant
- 2010-06-23 CA CA2800475A patent/CA2800475C/en active Active
- 2010-06-23 MX MX2012013955A patent/MX2012013955A/es active IP Right Grant
- 2010-06-23 EP EP10727321.1A patent/EP2585025B2/en active Active
- 2010-06-23 CN CN2010800675933A patent/CN102946841A/zh active Pending
- 2010-06-23 US US13/701,844 patent/US9579269B2/en active Active
- 2010-06-23 AU AU2010356102A patent/AU2010356102B2/en active Active
-
2011
- 2011-06-22 TW TW100121734A patent/TWI504415B/zh not_active IP Right Cessation
-
2012
- 2012-12-04 ZA ZA2012/09156A patent/ZA201209156B/en unknown
-
2013
- 2013-10-02 HK HK13111211.5A patent/HK1183802A1/xx not_active IP Right Cessation
-
2017
- 2017-01-20 US US15/411,211 patent/US11369553B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03128316A (ja) * | 1989-06-21 | 1991-05-31 | Yissum Res Dev Co Of Hebrew Univ Of Jerusalem | 液体重合体組成物及びその使用方法 |
JPH0627137A (ja) * | 1992-07-08 | 1994-02-04 | Murata Mfg Co Ltd | 加速度センサ |
WO2009099455A1 (en) * | 2008-02-08 | 2009-08-13 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
WO2009152507A2 (en) * | 2008-06-13 | 2009-12-17 | Colgate-Palmolive Company | Oral compositions and uses thereof |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017104664A1 (ja) * | 2015-12-14 | 2017-06-22 | 花王株式会社 | 液体口腔用組成物 |
JPWO2017104664A1 (ja) * | 2015-12-14 | 2018-09-27 | 花王株式会社 | 液体口腔用組成物 |
JP2020535166A (ja) * | 2017-09-29 | 2020-12-03 | スリーエム イノベイティブ プロパティズ カンパニー | 水性口腔ケアフッ化物処置組成物、及び方法 |
JP7273805B2 (ja) | 2017-09-29 | 2023-05-15 | スリーエム イノベイティブ プロパティズ カンパニー | 水性口腔ケアフッ化物処置組成物、及び方法 |
Also Published As
Publication number | Publication date |
---|---|
EP2585025A1 (en) | 2013-05-01 |
CA2800475C (en) | 2015-11-03 |
MX2012013955A (es) | 2013-01-24 |
ES2529216T3 (es) | 2015-02-18 |
EP2585025B2 (en) | 2022-10-26 |
TWI504415B (zh) | 2015-10-21 |
SG185631A1 (en) | 2012-12-28 |
WO2011162756A1 (en) | 2011-12-29 |
CN102946841A (zh) | 2013-02-27 |
BR112012030037B1 (pt) | 2017-06-27 |
TW201215410A (en) | 2012-04-16 |
CA2800475A1 (en) | 2011-12-29 |
JP5723001B2 (ja) | 2015-05-27 |
US11369553B2 (en) | 2022-06-28 |
RU2535088C2 (ru) | 2014-12-10 |
US20130078197A1 (en) | 2013-03-28 |
HK1183802A1 (en) | 2014-01-10 |
US20170128340A1 (en) | 2017-05-11 |
AU2010356102B2 (en) | 2013-09-05 |
EP2585025B1 (en) | 2014-12-03 |
US9579269B2 (en) | 2017-02-28 |
ZA201209156B (en) | 2016-08-31 |
PL2585025T3 (pl) | 2015-04-30 |
AU2010356102A1 (en) | 2012-12-13 |
BR112012030037A2 (pt) | 2016-08-02 |
RU2013102892A (ru) | 2014-07-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5723001B2 (ja) | 治療用口腔用組成物 | |
TWI399221B (zh) | 含有迷迭香萃取物之口腔組成物及相關方法 | |
JP5694506B2 (ja) | 口腔ケア組成物 | |
RU2469701C2 (ru) | Продукт для ухода за полостью рта и способы его применения | |
AU2010358075B2 (en) | Mouthwash formulations for use with toothbrush delivery device | |
TWI382852B (zh) | 一種口腔保健用磷酸鈣複合物及其製法與組合物 | |
KR101019873B1 (ko) | 치약 조성물 | |
US20160331670A1 (en) | Oral care compositions and methods | |
CN110636887A (zh) | 口腔护理组合物和使用方法 | |
CN105748305A (zh) | 治疗用口腔组合物 | |
RU2482835C2 (ru) | Продукт для ухода за ротовой полостью и способы его применения и изготовления | |
BR112019021767B1 (pt) | Método e composição de cuidado oral e uso de uma proteína vegetal parcialmente hidrolisada | |
EP4017472A1 (en) | Methods for improving barrier integrity of gingival tissue |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20130625 |
|
RD02 | Notification of acceptance of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7422 Effective date: 20140303 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20140320 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20140401 |
|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20140325 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20140630 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20140707 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140801 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20150224 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20150326 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5723001 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |