|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5567584A
(en)
|
1988-01-22 |
1996-10-22 |
Zymogenetics, Inc. |
Methods of using biologically active dimerized polypeptide fusions to detect PDGF
|
|
US20020099179A1
(en)
|
1989-12-21 |
2002-07-25 |
Linda K. Jolliffe |
Cdr-grafted antibodies
|
|
DK261490D0
(da)
|
1990-10-31 |
1990-10-31 |
Novo Nordisk As |
New pharmaceutical compound
|
|
US6165467A
(en)
|
1991-07-20 |
2000-12-26 |
Yoshihide Hagiwara |
Stabilized human monoclonal antibody preparation
|
|
US5789192A
(en)
|
1992-12-10 |
1998-08-04 |
Schering Corporation |
Mammalian receptors for interleukin-10 (IL-10)
|
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
|
JP3681206B2
(ja)
|
1995-12-26 |
2005-08-10 |
株式会社三菱化学ヤトロン |
抗ファクターXa・ティシュファクターパスウェイインヒビター複合体モノクローナル抗体及びその使用
|
|
KR100374737B1
(ko)
|
1996-06-28 |
2003-07-16 |
세이코 엡슨 가부시키가이샤 |
트랜지스터형성방법,그트랜지스터를포함하는회로,액티브매트릭스기판의제조방법,표시장치의제조방법,및프로젝터및전자기기
|
|
JP2001500369A
(ja)
|
1996-08-30 |
2001-01-16 |
ヒューマン ジノーム サイエンシーズ,インコーポレイテッド |
インターロイキン―19
|
|
US5985614A
(en)
|
1996-08-30 |
1999-11-16 |
Human Genome Sciences, Inc. |
Polynucleotides encoding interleukin-19
|
|
WO1999046281A2
(en)
|
1998-03-10 |
1999-09-16 |
Genentech, Inc. |
Novel polypeptides and nucleic acids encoding the same
|
|
US5945511A
(en)
|
1997-02-20 |
1999-08-31 |
Zymogenetics, Inc. |
Class II cytokine receptor
|
|
AU7266698A
(en)
|
1997-04-30 |
1998-11-24 |
Enzon, Inc. |
Polyalkylene oxide-modified single chain polypeptides
|
|
US6486301B1
(en)
|
1997-07-16 |
2002-11-26 |
Human Genome Sciences, Inc. |
Interleukin-20
|
|
WO1999003982A1
(en)
|
1997-07-16 |
1999-01-28 |
Human Genome Sciences, Inc. |
Interleukin-20
|
|
US6020163A
(en)
|
1997-08-06 |
2000-02-01 |
Zymogenetics, Inc. |
Lipocalin homolog
|
|
US6576743B1
(en)
|
1997-11-26 |
2003-06-10 |
Zymogenetics, Inc. |
Mammalian cytokine-like polypeptide-10
|
|
ATE272114T1
(de)
|
1998-01-23 |
2004-08-15 |
Immunex Corp |
Rezeptoren für il-18
|
|
JP2002505879A
(ja)
|
1998-03-09 |
2002-02-26 |
シェーリング コーポレイション |
ヒトレセプタータンパク質;関連する試薬および方法
|
|
US7198789B2
(en)
|
1998-03-17 |
2007-04-03 |
Genetics Institute, Llc |
Methods and compositions for modulating interleukin-21 receptor activity
|
|
CN1233476A
(zh)
|
1998-04-24 |
1999-11-03 |
陆道培 |
治疗急性白血病的药物及其制备方法
|
|
WO1999061630A2
(en)
|
1998-05-26 |
1999-12-02 |
Regeneron Pharmaceuticals, Inc. |
Chimeric molecules comprising an extracellular ligand binding domain of a receptor and an ige fc or constant region, and their use in an assay system
|
|
AU4411699A
(en)
|
1998-06-05 |
1999-12-20 |
Human Genome Sciences, Inc. |
Interferon receptor hkaef92
|
|
US7026448B2
(en)
|
1998-09-01 |
2006-04-11 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
BR9913857A
(pt)
|
1998-09-17 |
2001-06-12 |
Lilly Co Eli |
Formulações de proteìna
|
|
US6451286B1
(en)
*
|
1998-12-21 |
2002-09-17 |
Generex Pharmaceuticals Incorporated |
Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds
|
|
US7087215B2
(en)
*
|
1998-12-21 |
2006-08-08 |
Generex Pharmaceuticals Incorporated |
Methods of administering and enhancing absorption of pharmaceutical agents
|
|
AU2222700A
(en)
|
1998-12-31 |
2000-07-31 |
Millennium Pharmaceuticals, Inc. |
Class ii cytokine receptor-like proteins and nucleic acids encoding them
|
|
AU3774300A
(en)
|
1999-06-02 |
2000-12-18 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20050060101A1
(en)
|
1999-06-28 |
2005-03-17 |
Bevilacqua Michael P. |
Systems and methods for characterizing a biological condition or agent using precision gene expression profiles
|
|
CN1245216C
(zh)
|
1999-10-04 |
2006-03-15 |
希龙公司 |
稳定化的含多肽的液体药物组合物
|
|
KR100399156B1
(ko)
*
|
1999-11-19 |
2003-09-26 |
주식회사 엘지생명과학 |
α-인터페론의 용액제형
|
|
DE60045139D1
(de)
|
1999-12-23 |
2010-12-02 |
Zymogenetics Inc |
Löslicher Interleukin-20-Rezeptor
|
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
EP1272211B1
(en)
|
2000-04-07 |
2007-06-06 |
Signal Coordinating Therapy, Inc. |
Methods and compositions for treating neoplasms
|
|
US7015194B2
(en)
|
2000-05-10 |
2006-03-21 |
Novo Nordisk A/S |
Pharmaceutical composition comprising factor VIIa and anti-TFPI
|
|
JP5490972B2
(ja)
|
2000-08-04 |
2014-05-14 |
中外製薬株式会社 |
タンパク質注射製剤
|
|
EP2177616B1
(en)
|
2000-08-08 |
2012-02-29 |
ZymoGenetics, Inc. |
Soluble zcytor 11 cytokine receptors
|
|
JP5485489B2
(ja)
|
2000-08-11 |
2014-05-07 |
中外製薬株式会社 |
抗体含有安定化製剤
|
|
JP4340062B2
(ja)
|
2000-10-12 |
2009-10-07 |
ジェネンテック・インコーポレーテッド |
粘度の減少した濃縮タンパク質製剤
|
|
CA2433933A1
(en)
|
2001-02-28 |
2002-09-12 |
Eli Lilly And Company |
Use of lp82 to treat hematopoietic disorders
|
|
DK1399472T3
(da)
|
2001-03-09 |
2009-10-05 |
Zymogenetics Inc |
Oplöselig heterodimer cytokinreceptor
|
|
AU2002324556A1
(en)
*
|
2001-07-25 |
2003-02-17 |
Protein Design Labs, Inc. |
Stable lyophilized pharmaceutical formulation of igg antibodies
|
|
ES2629395T3
(es)
|
2001-10-04 |
2017-08-09 |
Genetics Institute, Llc |
Métodos y composiciones para modular la actividad de la interleucina-21
|
|
US7022289B1
(en)
|
2001-10-10 |
2006-04-04 |
The United States Of America As Represented By The Secretary Of The Army |
Chemical and biological sampling device and kit and method of use thereof
|
|
RU2318829C2
(ru)
*
|
2001-11-14 |
2008-03-10 |
Сентокор, Инк. |
Антитела против il-6, композиции, способы и применение
|
|
IL161978A0
(en)
|
2001-12-17 |
2005-11-20 |
Zymogenetics Inc |
Method for treating cervical cancer
|
|
EP3192528A1
(en)
|
2002-02-14 |
2017-07-19 |
Chugai Seiyaku Kabushiki Kaisha |
Formulation of anti-il6r antibody-containing solutions comprising a sugar as a stabilizer
|
|
SI1478394T1
(sl)
|
2002-02-27 |
2008-12-31 |
Immunex Corp |
STABILIZIRAN TNFR-Fc SESTAVEK Z ARGININOM
|
|
US20050063947A1
(en)
|
2002-03-27 |
2005-03-24 |
Patrick Hwu |
Method for treating cancer in humans
|
|
US20040009168A1
(en)
|
2002-04-05 |
2004-01-15 |
Elizabet Kaisheva |
Multidose antibody formulation
|
|
DK1531850T3
(da)
|
2002-06-07 |
2012-06-04 |
Zymogenetics Inc |
Anvendelse af 1L-21 og monoklonalt antistof til behandling af solide cancere
|
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
|
US20040022792A1
(en)
|
2002-06-17 |
2004-02-05 |
Ralph Klinke |
Method of stabilizing proteins at low pH
|
|
EP1551875A4
(en)
|
2002-06-21 |
2006-06-28 |
Biogen Idec Inc |
TAMPON PREPARATIONS FOR CONCENTRATING ANTIBODIES AND METHODS FOR USE THEREOF
|
|
BR0312767A
(pt)
|
2002-07-18 |
2005-05-03 |
Perini Fabio Spa |
Unidade de armazenamento para produtos alongados
|
|
US20040033228A1
(en)
|
2002-08-16 |
2004-02-19 |
Hans-Juergen Krause |
Formulation of human antibodies for treating TNF-alpha associated disorders
|
|
US20040191243A1
(en)
*
|
2002-12-13 |
2004-09-30 |
Bei Chen |
System and method for stabilizing antibodies with histidine
|
|
AU2004210679A1
(en)
|
2003-02-10 |
2004-08-26 |
Elan Pharmaceuticals, Inc. |
Immunoglobulin formulation and method of preparation thereof
|
|
AU2004229335C1
(en)
|
2003-04-04 |
2010-06-17 |
Genentech, Inc. |
High concentration antibody and protein formulations
|
|
MEP31508A
(hr)
|
2003-07-15 |
2010-10-10 |
Amgen Inc |
Humana anti-ngf neutrališuća antitijela kao selektivni ihibitori ngf signalne kaskade
|
|
US8496930B2
(en)
|
2003-10-01 |
2013-07-30 |
Kyowa Hakko Kirin Co., Ltd |
Method of stabilizing antibody and stabilized solution-type antibody preparation
|
|
EP1712240B1
(en)
|
2003-12-25 |
2015-09-09 |
Kyowa Hakko Kirin Co., Ltd. |
Stable water-based medicinal preparation containing antibody
|
|
EP1755677A4
(en)
|
2004-06-14 |
2009-11-25 |
Medimmune Vaccines Inc |
HIGH-PRESSURE SPRAY DRYING OF BIOACTIVE MATERIALS
|
|
EA015706B1
(ru)
|
2004-10-22 |
2011-10-31 |
Займоджинетикс, Инк. |
Моноклональное антитело или его фрагмент, связывающиеся с полипептидом il-22ra, гуманизированное антитело, полученное из указанного антитела, гибридомы, продуцирующие антитело, и применение указанного антитела
|
|
EP2192132A3
(en)
|
2005-02-08 |
2010-08-18 |
ZymoGenetics, Inc. |
Anti-IL-20, anti-IL22 and anti-IL-22RA antibodies and binding partners and methods of using in inflammation
|
|
US7525604B2
(en)
|
2005-03-15 |
2009-04-28 |
Naxellent, Llc |
Windows with electrically controllable transmission and reflection
|
|
ATE501248T1
(de)
|
2005-07-02 |
2011-03-15 |
Arecor Ltd |
Stabile wässrige systeme mit proteinen
|
|
WO2007006858A2
(en)
|
2005-07-12 |
2007-01-18 |
Oy Jurilab Ltd |
Method for treatment of cardiovascular and metabolic diseases and detecting the risk of the same
|
|
AU2006295340B2
(en)
|
2005-08-05 |
2010-11-11 |
Amgen Inc. |
Stable aqueous protein or antibody pharmaceutical formulations and their preparation
|
|
AU2006294477A1
(en)
|
2005-09-27 |
2007-04-05 |
Source Mdx |
Gene expression profiling for identification monitoring and treatment of rheumatoid arthritis
|
|
WO2007038501A2
(en)
|
2005-09-27 |
2007-04-05 |
The Feinstein Institute For Medical Research |
Rheumatoid arthritis markers
|
|
JP5138601B2
(ja)
|
2005-11-21 |
2013-02-06 |
サノフィ パストゥール リミテッド |
組換えウイルス安定化製剤
|
|
JP5405122B2
(ja)
|
2005-12-21 |
2014-02-05 |
ワイス・エルエルシー |
低粘度のタンパク質製剤およびその用途
|
|
JP5231810B2
(ja)
|
2005-12-28 |
2013-07-10 |
中外製薬株式会社 |
抗体含有安定化製剤
|
|
JP2009525986A
(ja)
|
2006-02-03 |
2009-07-16 |
メディミューン,エルエルシー |
タンパク質製剤
|
|
DE102006005094A1
(de)
|
2006-02-04 |
2007-08-09 |
Degussa Gmbh |
Titandioxid und Polycarboxylatether enthaltende Dispersion
|
|
TW200744634A
(en)
|
2006-02-21 |
2007-12-16 |
Wyeth Corp |
Methods of using antibodies against human IL-22
|
|
EP2005279A2
(en)
|
2006-03-15 |
2008-12-24 |
Koninklijke Philips Electronics N.V. |
Remote control pointing technology with roll detection
|
|
TW200806317A
(en)
|
2006-03-20 |
2008-02-01 |
Wyeth Corp |
Methods for reducing protein aggregation
|
|
TW200808347A
(en)
|
2006-03-23 |
2008-02-16 |
Kirin Brewery |
Agonistic antibody directed against human thrombopoietin receptor
|
|
KR20080104160A
(ko)
*
|
2006-03-28 |
2008-12-01 |
에프. 호프만-라 로슈 아게 |
항-igf-1r 인간 단일클론 항체 제형
|
|
EP1857559A1
(en)
|
2006-05-16 |
2007-11-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A method for predicting responsiveness to TNF alpha blocking agents
|
|
AU2007260769A1
(en)
|
2006-06-14 |
2007-12-21 |
Imclone Llc |
Lyophilized formulations of anti-EGFR antibodies
|
|
CN101472611A
(zh)
|
2006-06-19 |
2009-07-01 |
惠氏公司 |
调节il-22和il-17的方法
|
|
ES2656359T3
(es)
|
2006-06-30 |
2018-02-26 |
Novo Nordisk A/S |
Anticuerpos anti-NKG2A y usos de los mismos
|
|
EP2081553B1
(en)
|
2006-10-06 |
2020-08-12 |
Amgen Inc. |
Stable antibody formulations
|
|
MX2009003542A
(es)
|
2006-10-12 |
2009-04-15 |
Wyeth Corp |
Metodos y composiciones con opalescencia reducida.
|
|
US20100267575A1
(en)
|
2006-10-17 |
2010-10-21 |
Childrens Hospital Medical Center |
Gene array technique for predicting response in inflammatory bowel diseases
|
|
WO2008056198A1
(en)
|
2006-11-09 |
2008-05-15 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Method for predicting therapeutic responsiveness to tnf-alpha blocking agents
|
|
CN101553504A
(zh)
|
2006-12-11 |
2009-10-07 |
豪夫迈·罗氏有限公司 |
Aβ抗体胃肠外制剂
|
|
WO2008086395A2
(en)
*
|
2007-01-09 |
2008-07-17 |
Wyeth |
Anti-il-13 antibody formulations and uses thereof
|
|
EP2132343B1
(en)
|
2007-03-01 |
2012-08-29 |
Université Catholique de Louvain |
Method for the determination and the classification of rheumatic conditions
|
|
KR101087344B1
(ko)
|
2007-03-23 |
2011-11-25 |
파나소닉 주식회사 |
도전성 범프와 그 제조 방법 및 전자 부품 실장 구조체
|
|
US20100209434A1
(en)
|
2007-03-30 |
2010-08-19 |
Medimmune, Llc |
Antibody formulation
|
|
GB0707938D0
(en)
|
2007-04-25 |
2007-05-30 |
Univ Strathclyde |
Precipitation stabilising compositions
|
|
WO2008132176A2
(en)
|
2007-04-27 |
2008-11-06 |
Universite Catholique De Louvain |
Method for evaluating the response of an individual to tnf blocking therapy
|
|
MX2009013410A
(es)
|
2007-06-08 |
2010-03-22 |
Biogen Idec Inc |
Biomarcadores para predecir capacidad de respuesta anti-tnf o sin capacidad de respuesta.
|
|
NZ595526A
(en)
|
2007-06-14 |
2013-03-28 |
Biogen Idec Inc |
Pharmaceutical composition comprising a vla-4 binding antibody, a phosphate buffer and a surfactant
|
|
US20090208492A1
(en)
|
2007-06-14 |
2009-08-20 |
Elan Pharmaceuticals, Inc. |
Lyophilized Immunoglobulin Formulations and Methods of Preparation
|
|
WO2008157282A1
(en)
|
2007-06-18 |
2008-12-24 |
Genentech, Inc. |
Biological markers predictive of rheumatoid arthritis response to b-cell antagonists
|
|
US7951368B2
(en)
|
2007-06-25 |
2011-05-31 |
Amgen Inc. |
Compositions of specific binding agents to hepatocyte growth factor
|
|
UA107557C2
(xx)
|
2007-07-06 |
2015-01-26 |
|
Композиція антитіла офатумумабу
|
|
EP2173163A4
(en)
|
2007-07-06 |
2010-12-08 |
Glaxosmithkline Llc |
ANTIBODY FORMULATIONS
|
|
EP2174132A2
(en)
|
2007-07-20 |
2010-04-14 |
National Institute for Bioprocessing Research and Training Limited |
Glycosylation markers for cancer and chronic inflammation
|
|
US20100261613A1
(en)
|
2007-07-26 |
2010-10-14 |
Michael Centola |
Methods for inflammatory disease management
|
|
WO2009070642A1
(en)
|
2007-11-28 |
2009-06-04 |
Medimmune, Llc |
Protein formulation
|
|
DK2222706T4
(en)
|
2007-12-14 |
2016-11-21 |
Novo Nordisk As |
Antibodies that bind to NKG2D and its use
|
|
CN104193824A
(zh)
|
2008-02-20 |
2014-12-10 |
G2炎症私人有限公司 |
人源化抗-C5aR抗体
|
|
WO2009120684A1
(en)
|
2008-03-25 |
2009-10-01 |
Medimmune, Llc |
Antibody formulation
|
|
EP2281000A2
(en)
|
2008-05-15 |
2011-02-09 |
Novo Nordisk A/S |
Antibody purification process
|
|
TWI451876B
(zh)
*
|
2008-06-13 |
2014-09-11 |
Lilly Co Eli |
聚乙二醇化之離脯胰島素化合物
|
|
RU2011101969A
(ru)
|
2008-06-30 |
2012-08-10 |
Ново Нордиск А/С (DK) |
Антитела к человеческому интерлейкину-20
|
|
UA112050C2
(uk)
*
|
2008-08-04 |
2016-07-25 |
БАЄР ХЕЛСКЕР ЛЛСі |
Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi)
|
|
KR20110048536A
(ko)
|
2008-08-28 |
2011-05-11 |
와이어쓰 엘엘씨 |
자가면역 질병에서 il-22, il-17 및 il-1 패밀리 시토킨의 용도
|
|
BRPI0918419A2
(pt)
|
2008-09-19 |
2015-11-24 |
Hoffmann La Roche |
nova formulação anticorpo
|
|
EP2196476A1
(en)
|
2008-12-10 |
2010-06-16 |
Novartis Ag |
Antibody formulation
|
|
CN102325795B
(zh)
*
|
2008-12-22 |
2015-03-25 |
诺沃—诺迪斯克有限公司 |
针对组织因子途径抑制剂的抗体
|
|
US20120020954A1
(en)
|
2009-03-30 |
2012-01-26 |
Anat Achiron |
Methods of predicting clinical course and treating multiple sclerosis
|
|
BR112012004777A2
(pt)
|
2009-09-03 |
2019-09-24 |
Genentech Inc |
métodos para tratar diagnósticar e monitorar artrite reumatoide
|
|
WO2011047073A2
(en)
|
2009-10-16 |
2011-04-21 |
Mayo Foundation For Medical Education And Research |
Assessing rheumatoid arthritis
|
|
US8580528B2
(en)
|
2009-10-16 |
2013-11-12 |
Stichting Vu-Vumc |
Method for prognosticating the clinical response of a patient to B-lymphocyte inhibiting or depleting therapy
|
|
EP3409289B1
(en)
|
2010-02-26 |
2020-09-30 |
Novo Nordisk A/S |
Stable antibody containing compositions
|
|
RU2012153786A
(ru)
|
2010-05-28 |
2014-07-10 |
Ново Нордиск А/С |
Стабильные многодозовые композиции, содержащие антитело и консервант
|
|
CA2801107A1
(en)
|
2010-06-07 |
2011-12-15 |
F. Hoffman-La Roche Ag |
Gene expression markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment
|
|
US8603470B1
(en)
|
2012-08-07 |
2013-12-10 |
National Cheng Kung University |
Use of IL-20 antagonists for treating liver diseases
|