JP2013523634A - 溶融押出フィルム - Google Patents

溶融押出フィルム Download PDF

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Publication number
JP2013523634A
JP2013523634A JP2013501272A JP2013501272A JP2013523634A JP 2013523634 A JP2013523634 A JP 2013523634A JP 2013501272 A JP2013501272 A JP 2013501272A JP 2013501272 A JP2013501272 A JP 2013501272A JP 2013523634 A JP2013523634 A JP 2013523634A
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JP
Japan
Prior art keywords
film
water
melt
soluble polymer
adjuvant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013501272A
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English (en)
Japanese (ja)
Other versions
JP2013523634A5 (enExample
Inventor
ホール マーク
リード マイケル
シュレスタ ウマ
Original Assignee
ダウ グローバル テクノロジーズ エルエルシー
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Application filed by ダウ グローバル テクノロジーズ エルエルシー filed Critical ダウ グローバル テクノロジーズ エルエルシー
Publication of JP2013523634A publication Critical patent/JP2013523634A/ja
Publication of JP2013523634A5 publication Critical patent/JP2013523634A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/18—Manufacture of films or sheets
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
    • C08J2301/08—Cellulose derivatives
    • C08J2301/26—Cellulose ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/02—Polyalkylene oxides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2013501272A 2010-03-26 2011-02-25 溶融押出フィルム Pending JP2013523634A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31789610P 2010-03-26 2010-03-26
US61/317,896 2010-03-26
PCT/US2011/026225 WO2011119287A1 (en) 2010-03-26 2011-02-25 Melt-extruded film

Publications (2)

Publication Number Publication Date
JP2013523634A true JP2013523634A (ja) 2013-06-17
JP2013523634A5 JP2013523634A5 (enExample) 2014-04-10

Family

ID=43974961

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013501272A Pending JP2013523634A (ja) 2010-03-26 2011-02-25 溶融押出フィルム

Country Status (7)

Country Link
US (1) US20110236465A1 (enExample)
EP (1) EP2553003A1 (enExample)
JP (1) JP2013523634A (enExample)
KR (1) KR20130080004A (enExample)
CN (1) CN102892815B (enExample)
BR (1) BR112012018523A2 (enExample)
WO (1) WO2011119287A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017175792A1 (ja) * 2016-04-06 2017-10-12 アステラス製薬株式会社 速溶出性三次元造形物、速溶出性三次元造形物用フィラメント及び速溶出性三次元造形物用材料
JP2020521870A (ja) * 2017-05-26 2020-07-27 インフィニット・マテリアル・ソリューションズ，エルエルシー 水溶性ポリマー組成物

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013154981A1 (en) 2012-04-11 2013-10-17 Dow Global Technologies Llc Melt-extruded composition comprising a cellulose ether
CN105209084B (zh) 2013-03-13 2018-07-03 艾利丹尼森公司 改善的粘合性能
BR112015019575A2 (pt) * 2013-04-12 2017-07-18 Dow Global Technologies Llc polissacarídeo solúvel em água livre de amido, alimento, ingrediente de alimento, ou suplemento alimentício e método para melhorar a palatabilidade de um polissacarídeo solúvel em água livre de amido
WO2017009446A1 (en) * 2015-07-16 2017-01-19 Christer Sjögren Compositions of midazolam for buccal administration in the treatment of seizures to obtain rapid onset of action
CN106421799B (zh) * 2016-09-05 2022-03-15 四川大学 一种制备交替层状生物降解高分子药物控释复合材料的方法
CN108553451A (zh) * 2018-05-23 2018-09-21 戴铭骏 一种头孢克肟口腔速溶膜剂及其制备方法
JP6905035B2 (ja) 2019-11-29 2021-07-21 Ｎｉｓｓｈａ株式会社 可食性フィルムの製造方法、フィルム製剤及び可食性フィルム

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05239265A (ja) * 1991-06-17 1993-09-17 Ems Inventa Ag デンプン−ポリマー混合物、その製法及びこれから得られる熱可塑性成形品
JPH10179045A (ja) * 1996-12-25 1998-07-07 Osaka Kagaku Gokin Kk シート状可食性成形物
US20010006677A1 (en) * 1996-10-29 2001-07-05 Mcginity James W. Effervescence polymeric film drug delivery system
JP2002530454A (ja) * 1998-11-17 2002-09-17 セラニーズ ベンチャーズ ゲー・エム・ベー・ハー ポリ（α−１，４−Ｄ−グルカン）およびそれを含有する熱可塑性ポリマー混合物
JP2007519745A (ja) * 2004-01-30 2007-07-19 コリウム インターナショナル， インコーポレイテッド 活性物質の送達のための急速に溶解するフィルム
JP2008063582A (ja) * 2001-09-28 2008-03-21 Mitsubishi Plastics Ind Ltd 乳酸系樹脂組成物、過酸化物変性乳酸系樹脂組成物、並びに、それらの成形体
JP2009531453A (ja) * 2006-03-24 2009-09-03 オクシリウム インターナショナル ホールディングス，インコーポレイティド アルカリ不安定ドラッグを含む安定化された組成物
JP2009531452A (ja) * 2006-03-24 2009-09-03 オクシリウム インターナショナル ホールディングス，インコーポレイティド ホットメルト押出しラミネートの調製方法
WO2010002418A2 (en) * 2008-07-01 2010-01-07 The Johns Hopkins University Quick-dissolving oral thin film for targeted delivery of therapeutic agents

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645812A (en) 1983-02-28 1987-02-24 Henkel Corporation Method of suspension polymerization of vinyl chloride
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
DE4018247A1 (de) * 1990-06-07 1991-12-12 Lohmann Therapie Syst Lts Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen
TW207987B (enExample) 1991-03-20 1993-06-21 Hoechst Ag
DE69222847T3 (de) * 1991-04-16 2005-09-15 Nippon Shinyaku Co., Ltd. Verfahren zur herstellung einer festen dispersion
DE19509805A1 (de) * 1995-03-21 1996-09-26 Basf Ag Transparente, schnell freisetzende Zubereitungen von nichtsteroidalen Analgetica
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
ES2295541T5 (es) * 2003-01-08 2012-06-27 Swiss Caps Rechte Und Lizenzen Ag Cuerpos moldeados constituidos por material exento de gelatina y rellenos con una masa de carga líquida
JP2007526209A (ja) * 2003-04-14 2007-09-13 エフ　エム　シー　コーポレーション 均一かつ熱可逆性低粘度ポリマンナンフィルムの伝達システム
ITMI20032087A1 (it) * 2003-10-27 2005-04-28 Pharmafilm S R L Film autosupportanti per uso farmaceutico ed alimentare.
US20050208108A1 (en) * 2004-03-19 2005-09-22 Jannusch Leonard C Thermoplastic films and methods for making
DE602006019320D1 (de) * 2006-01-19 2011-02-10 Dow Global Technologies Inc Biologisch wirksame zusammensetzung mit ethylcellulose
US8759279B2 (en) * 2008-06-30 2014-06-24 Kimberly-Clark Worldwide, Inc. Fragranced biodegradable film
WO2011081625A1 (en) * 2009-12-30 2011-07-07 Novartis Ag Melt extruded thin strips containing coated pharmaceutical actives

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05239265A (ja) * 1991-06-17 1993-09-17 Ems Inventa Ag デンプン−ポリマー混合物、その製法及びこれから得られる熱可塑性成形品
US20010006677A1 (en) * 1996-10-29 2001-07-05 Mcginity James W. Effervescence polymeric film drug delivery system
JPH10179045A (ja) * 1996-12-25 1998-07-07 Osaka Kagaku Gokin Kk シート状可食性成形物
JP2002530454A (ja) * 1998-11-17 2002-09-17 セラニーズ ベンチャーズ ゲー・エム・ベー・ハー ポリ（α−１，４−Ｄ−グルカン）およびそれを含有する熱可塑性ポリマー混合物
JP2008063582A (ja) * 2001-09-28 2008-03-21 Mitsubishi Plastics Ind Ltd 乳酸系樹脂組成物、過酸化物変性乳酸系樹脂組成物、並びに、それらの成形体
JP2007519745A (ja) * 2004-01-30 2007-07-19 コリウム インターナショナル， インコーポレイテッド 活性物質の送達のための急速に溶解するフィルム
JP2009531453A (ja) * 2006-03-24 2009-09-03 オクシリウム インターナショナル ホールディングス，インコーポレイティド アルカリ不安定ドラッグを含む安定化された組成物
JP2009531452A (ja) * 2006-03-24 2009-09-03 オクシリウム インターナショナル ホールディングス，インコーポレイティド ホットメルト押出しラミネートの調製方法
WO2010002418A2 (en) * 2008-07-01 2010-01-07 The Johns Hopkins University Quick-dissolving oral thin film for targeted delivery of therapeutic agents

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017175792A1 (ja) * 2016-04-06 2017-10-12 アステラス製薬株式会社 速溶出性三次元造形物、速溶出性三次元造形物用フィラメント及び速溶出性三次元造形物用材料
JPWO2017175792A1 (ja) * 2016-04-06 2019-02-14 アステラス製薬株式会社 速溶出性三次元造形物、速溶出性三次元造形物用フィラメント及び速溶出性三次元造形物用材料
US12377601B2 (en) 2016-04-06 2025-08-05 Astellas Pharma Inc. Fast-eluting three-dimensionally molded object, filament for fast-eluting three-dimensionally molded object, and material for fast-eluting three-dimensionally molded object
JP2020521870A (ja) * 2017-05-26 2020-07-27 インフィニット・マテリアル・ソリューションズ，エルエルシー 水溶性ポリマー組成物
JP2023126752A (ja) * 2017-05-26 2023-09-12 インフィニット・マテリアル・ソリューションズ，エルエルシー 水溶性ポリマー組成物
JP7358340B2 (ja) 2017-05-26 2023-10-10 インフィニット・マテリアル・ソリューションズ，エルエルシー 水溶性ポリマー組成物
JP7661395B2 (ja) 2017-05-26 2025-04-14 インターフェイシャル・コンサルタンツ・エルエルシー 水溶性ポリマー組成物

Also Published As

Publication number Publication date
EP2553003A1 (en) 2013-02-06
CN102892815B (zh) 2016-05-18
CN102892815A (zh) 2013-01-23
US20110236465A1 (en) 2011-09-29
WO2011119287A1 (en) 2011-09-29
KR20130080004A (ko) 2013-07-11
BR112012018523A2 (pt) 2019-09-24

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