JP2013522168A5 - - Google Patents
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- Publication number
- JP2013522168A5 JP2013522168A5 JP2012554034A JP2012554034A JP2013522168A5 JP 2013522168 A5 JP2013522168 A5 JP 2013522168A5 JP 2012554034 A JP2012554034 A JP 2012554034A JP 2012554034 A JP2012554034 A JP 2012554034A JP 2013522168 A5 JP2013522168 A5 JP 2013522168A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- seq
- cargo molecule
- fusion protein
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33837710P | 2010-02-17 | 2010-02-17 | |
| US61/338,377 | 2010-02-17 | ||
| PCT/US2011/025312 WO2011103339A1 (en) | 2010-02-17 | 2011-02-17 | Use of pten-long leader sequence for transmembrane delivery of molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013522168A JP2013522168A (ja) | 2013-06-13 |
| JP2013522168A5 true JP2013522168A5 (enExample) | 2014-05-08 |
| JP6009360B2 JP6009360B2 (ja) | 2016-10-19 |
Family
ID=44483307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012554034A Expired - Fee Related JP6009360B2 (ja) | 2010-02-17 | 2011-02-17 | 分子の膜通過送達のためのｐｔｅｎロングリーダー配列の使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9074011B2 (enExample) |
| EP (1) | EP2536420A4 (enExample) |
| JP (1) | JP6009360B2 (enExample) |
| CN (1) | CN102844043B (enExample) |
| AU (1) | AU2011218037B2 (enExample) |
| BR (1) | BR112012020556A8 (enExample) |
| CA (4) | CA2790046C (enExample) |
| MX (1) | MX2012009565A (enExample) |
| WO (1) | WO2011103339A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2623393T3 (es) | 2009-02-17 | 2017-07-11 | The Trustees Of Columbia University In The City Of New York | Identificación de la forma extracelular de PTEN que puede usarse para tratar tumores |
| CN102844050B (zh) | 2010-02-19 | 2019-02-05 | 康奈尔大学 | 自身免疫性脱髓鞘疾病及其它自身免疫疾病或炎性疾病的治疗方法 |
| US11116851B2 (en) * | 2015-10-19 | 2021-09-14 | University Of Massachusetts | Anti-cancer and anti-inflammatory therapeutics and methods thereof |
| US20200085890A1 (en) * | 2016-07-29 | 2020-03-19 | Ohio State Innovation Foundation | Expression of pten-long with ocolytic viruses |
| CN109022462B (zh) * | 2017-06-08 | 2021-12-21 | 中山大学附属第一医院 | 一种PTEN基因的上游开放阅读框31aa-uORF核苷酸及其编码的多肽的应用 |
| CN108504671A (zh) * | 2018-03-28 | 2018-09-07 | 宁波市医疗中心李惠利医院 | 一种PTEN-Long蛋白纯化制备方法 |
| CN108484780A (zh) * | 2018-04-16 | 2018-09-04 | 河南大学 | 一种融合蛋白PTEN-L-p53及其应用 |
| CN109224075B (zh) * | 2018-08-07 | 2021-11-16 | 浙江大学 | Pten抑制剂在制备治疗1型糖尿病药物中的应用 |
| CN114127122A (zh) * | 2019-04-12 | 2022-03-01 | 治疗生物科学公司 | 制备磷酸酶与张力蛋白同源物（pten）融合物的组合物和方法 |
| CN112877309B (zh) * | 2021-02-19 | 2022-05-17 | 北京大学 | 一种N端延长型PTEN亚型PTENζ蛋白及其编码基因和应用 |
| CN113666998B (zh) * | 2021-08-10 | 2023-03-21 | 北京大学 | 一种具有调控神经系统发育功能的PTEN亚型蛋白PTENδ及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6482795B1 (en) | 1997-01-30 | 2002-11-19 | Myriad Genetics, Inc. | Tumor suppressor designated TS10q23.3 |
| ES2623393T3 (es) | 2009-02-17 | 2017-07-11 | The Trustees Of Columbia University In The City Of New York | Identificación de la forma extracelular de PTEN que puede usarse para tratar tumores |
-
2011
- 2011-02-17 AU AU2011218037A patent/AU2011218037B2/en not_active Ceased
- 2011-02-17 WO PCT/US2011/025312 patent/WO2011103339A1/en not_active Ceased
- 2011-02-17 CA CA2790046A patent/CA2790046C/en not_active Expired - Fee Related
- 2011-02-17 CA CA3017701A patent/CA3017701C/en not_active Expired - Fee Related
- 2011-02-17 CA CA3017717A patent/CA3017717A1/en not_active Abandoned
- 2011-02-17 MX MX2012009565A patent/MX2012009565A/es active IP Right Grant
- 2011-02-17 BR BR112012020556A patent/BR112012020556A8/pt not_active Application Discontinuation
- 2011-02-17 CA CA3017689A patent/CA3017689A1/en not_active Abandoned
- 2011-02-17 CN CN201180018210.8A patent/CN102844043B/zh not_active Expired - Fee Related
- 2011-02-17 US US13/579,025 patent/US9074011B2/en not_active Expired - Fee Related
- 2011-02-17 EP EP11745260.7A patent/EP2536420A4/en not_active Withdrawn
- 2011-02-17 JP JP2012554034A patent/JP6009360B2/ja not_active Expired - Fee Related
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