JP2013520473A5 - - Google Patents
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- Publication number
- JP2013520473A5 JP2013520473A5 JP2012554348A JP2012554348A JP2013520473A5 JP 2013520473 A5 JP2013520473 A5 JP 2013520473A5 JP 2012554348 A JP2012554348 A JP 2012554348A JP 2012554348 A JP2012554348 A JP 2012554348A JP 2013520473 A5 JP2013520473 A5 JP 2013520473A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- methyl
- substituted
- thieno
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10154928 | 2010-02-26 | ||
| EP10154928.5 | 2010-02-26 | ||
| PCT/EP2011/052811 WO2011104338A1 (en) | 2010-02-26 | 2011-02-25 | Halogen or cyano substituted thieno [2,3-d]pyrimidines having mnk1/mnk2 inhibiting activity for pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013520473A JP2013520473A (ja) | 2013-06-06 |
| JP2013520473A5 true JP2013520473A5 (enExample) | 2014-04-03 |
Family
ID=43907102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012554348A Ceased JP2013520473A (ja) | 2010-02-26 | 2011-02-25 | 医薬組成物用のＭｎｋ１／Ｍｎｋ２阻害活性を有するハロゲン又はシアノ置換されたチエノ［２，３−ｄ］ピリミジン |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20130065914A1 (enExample) |
| EP (1) | EP2539344B1 (enExample) |
| JP (1) | JP2013520473A (enExample) |
| WO (1) | WO2011104338A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050080026A1 (en) * | 2001-10-29 | 2005-04-14 | Arnd Steuernagel | Mnk kinase homologous proteins involved in the regulation of energy homeostasis and organelle metabolism |
| JP5302883B2 (ja) | 2006-04-07 | 2013-10-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬組成物用のｍｎｋ１／ｍｎｋ２阻害活性を有するチエノピリミジン |
| EP1889847A1 (en) | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Pyrrolopyrimidines for pharmaceutical compositions |
| KR20110045019A (ko) | 2008-08-26 | 2011-05-03 | 베링거 인겔하임 인터내셔날 게엠베하 | 약제학적 조성물을 위한 티에노피리미딘 |
| UY33241A (es) * | 2010-02-26 | 2011-09-30 | Boehringer Ingelheim Int | ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?. |
| AR080328A1 (es) * | 2010-02-26 | 2012-03-28 | Boehringer Ingelheim Int | Tienopirimidinas que contienen un grupo alquilo sustituido inhibidoras de quinasas mnk1 y/o mnk2, composiciones farmaceuticas que las contienen y uso de las mismas para el tratamiento de trastornos metabolicos tales como diabetes y obesidad, y trastornos hiperproliferativos, entre otros |
| EA201201191A1 (ru) | 2010-02-26 | 2013-04-30 | Бёрингер Ингельхайм Интернациональ Гмбх | 4-[циклоалкилокси(гетеро)ариламино]тиено[2,3-d]пиримидины, обладающие ингибирующей активностью по отношению к mnkl/mnk2, предназначенные для фармацевтических композиций |
| KR101570404B1 (ko) * | 2010-03-24 | 2015-11-20 | 르 라보레또레 쎄르비에르 | 결장직장암 및 위창자암의 예방 |
| CA2873967A1 (en) | 2012-05-21 | 2013-11-28 | Bayer Pharma Aktiengesellschaft | Substituted benzothienopyrimidines |
| EP2852596B1 (en) | 2012-05-21 | 2016-06-22 | Bayer Pharma Aktiengesellschaft | Thienopyrimidines |
| TW201412740A (zh) | 2012-09-20 | 2014-04-01 | Bayer Pharma AG | 經取代之吡咯并嘧啶胺基苯并噻唑酮 |
| EP2951175B1 (en) | 2013-02-01 | 2017-10-04 | Bayer Pharma Aktiengesellschaft | Substituted pyrazolopyrimidinylamino-indazoles |
| CA2899665A1 (en) | 2013-02-01 | 2014-08-07 | Bayer Pharma Aktiengesellschaft | Substituted thienopyrimidines and pharmaceutical use thereof |
| WO2014135480A1 (en) | 2013-03-06 | 2014-09-12 | Bayer Pharma Aktiengesellschaft | Substituted thiazolopyrimidines |
| AU2017239932A1 (en) * | 2016-03-31 | 2018-10-25 | Ocean University Of China | Method of inhibiting high fat diet-related conditions |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6643277B2 (en) | 2000-06-29 | 2003-11-04 | Harris Broadband Wireless Access, Inc. | Frequency re-use for point to multipoint applications |
| SE0102147D0 (sv) | 2001-06-18 | 2001-06-18 | Pharmacia Ab | New methods |
| US20050080026A1 (en) | 2001-10-29 | 2005-04-14 | Arnd Steuernagel | Mnk kinase homologous proteins involved in the regulation of energy homeostasis and organelle metabolism |
| US20050012622A1 (en) | 2003-05-19 | 2005-01-20 | Sutton William R. | Monitoring and control of sleep cycles |
| EP1746099A1 (en) | 2004-12-23 | 2007-01-24 | DeveloGen Aktiengesellschaft | Mnk1 or Mnk2 inhibitors |
| EP1899353A1 (en) | 2005-06-22 | 2008-03-19 | DeveloGen Aktiengesellschaft | Thienopyrimidines for pharmaceutical compositions |
| US20070099877A1 (en) * | 2005-11-02 | 2007-05-03 | Cytovia, Inc. | N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| WO2007059905A2 (en) * | 2005-11-25 | 2007-05-31 | Develogen Aktiengesellschaft | Thienopyrimidines treating inflammatory diseases |
| JP5302883B2 (ja) * | 2006-04-07 | 2013-10-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬組成物用のｍｎｋ１／ｍｎｋ２阻害活性を有するチエノピリミジン |
| EP1889847A1 (en) * | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Pyrrolopyrimidines for pharmaceutical compositions |
| KR20110045019A (ko) * | 2008-08-26 | 2011-05-03 | 베링거 인겔하임 인터내셔날 게엠베하 | 약제학적 조성물을 위한 티에노피리미딘 |
-
2011
- 2011-02-25 US US13/580,184 patent/US20130065914A1/en not_active Abandoned
- 2011-02-25 JP JP2012554348A patent/JP2013520473A/ja not_active Ceased
- 2011-02-25 EP EP11706530.0A patent/EP2539344B1/en not_active Not-in-force
- 2011-02-25 WO PCT/EP2011/052811 patent/WO2011104338A1/en not_active Ceased