JP2013520473A5 - - Google Patents

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Publication number
JP2013520473A5
JP2013520473A5 JP2012554348A JP2012554348A JP2013520473A5 JP 2013520473 A5 JP2013520473 A5 JP 2013520473A5 JP 2012554348 A JP2012554348 A JP 2012554348A JP 2012554348 A JP2012554348 A JP 2012554348A JP 2013520473 A5 JP2013520473 A5 JP 2013520473A5
Authority
JP
Japan
Prior art keywords
alkyl
group
methyl
substituted
thieno
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2012554348A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013520473A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2011/052811 external-priority patent/WO2011104338A1/en
Publication of JP2013520473A publication Critical patent/JP2013520473A/ja
Publication of JP2013520473A5 publication Critical patent/JP2013520473A5/ja
Ceased legal-status Critical Current

Links

JP2012554348A 2010-02-26 2011-02-25 医薬組成物用のＭｎｋ１／Ｍｎｋ２阻害活性を有するハロゲン又はシアノ置換されたチエノ［２，３−ｄ］ピリミジン Ceased JP2013520473A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10154928 2010-02-26
EP10154928.5 2010-02-26
PCT/EP2011/052811 WO2011104338A1 (en) 2010-02-26 2011-02-25 Halogen or cyano substituted thieno [2,3-d]pyrimidines having mnk1/mnk2 inhibiting activity for pharmaceutical compositions

Publications (2)

Publication Number Publication Date
JP2013520473A JP2013520473A (ja) 2013-06-06
JP2013520473A5 true JP2013520473A5 (enExample) 2014-04-03

Family

ID=43907102

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012554348A Ceased JP2013520473A (ja) 2010-02-26 2011-02-25 医薬組成物用のＭｎｋ１／Ｍｎｋ２阻害活性を有するハロゲン又はシアノ置換されたチエノ［２，３−ｄ］ピリミジン

Country Status (4)

Country Link
US (1) US20130065914A1 (enExample)
EP (1) EP2539344B1 (enExample)
JP (1) JP2013520473A (enExample)
WO (1) WO2011104338A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60238929D1 (de) * 2001-10-29 2011-02-24 Boehringer Ingelheim Int Mnk-kinase-homologe proteine, die an der regulierung der energiehomöostase und dem organellen metabolismus beteiligt sind
US8633201B2 (en) 2006-04-07 2014-01-21 Boehringer Ingelheim International Gmbh Thienopyrimidines having Mnk1/Mnk2 inhibiting activity for pharmaceutical compositions
EP1889847A1 (en) 2006-07-10 2008-02-20 DeveloGen Aktiengesellschaft Pyrrolopyrimidines for pharmaceutical compositions
EP2331551B1 (en) 2008-08-26 2016-06-29 Evotec International GmbH Thienopyrimidines for pharmaceutical compositions
EP2539343B1 (en) * 2010-02-26 2015-12-30 Evotec International GmbH Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions
JP5575274B2 (ja) * 2010-02-26 2014-08-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物のためのｍｎｋｌ／ｍｎｋ２阻害活性を有する４−［シクロアルキルオキシ（ヘテロ）アリールアミノ］チエノ「２，３−ｄ］ピリミジン
UY33241A (es) 2010-02-26 2011-09-30 Boehringer Ingelheim Int ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
EA036967B1 (ru) * 2010-03-24 2021-01-20 Ле Лаборатуар Сервье Профилактика колоректального и желудочно-кишечного рака
JP6235001B2 (ja) 2012-05-21 2017-11-22 バイエル・ファルマ・アクティエンゲゼルシャフト 置換ベンゾチエノピリミジン
CN104507950B (zh) 2012-05-21 2017-03-22 拜耳医药股份有限公司 噻吩并嘧啶
TW201412740A (zh) 2012-09-20 2014-04-01 Bayer Pharma AG 經取代之吡咯并嘧啶胺基苯并噻唑酮
EP2951187A1 (en) 2013-02-01 2015-12-09 Bayer Pharma Aktiengesellschaft Substituted thienopyrimidines and pharmaceutical use thereof
ES2653419T3 (es) 2013-02-01 2018-02-07 Bayer Pharma Aktiengesellschaft Pirazolopirimidinilamino-indazoles sustituidos
US9675612B2 (en) 2013-03-06 2017-06-13 Bayer Pharma Aktiengesellschaft Substituted thiazolopyrimidines
US20190117657A1 (en) * 2016-03-31 2019-04-25 South Australian Health And Medical Research Institute Limited Method of inhibiting high fat diet-related conditions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6643277B2 (en) 2000-06-29 2003-11-04 Harris Broadband Wireless Access, Inc. Frequency re-use for point to multipoint applications
SE0102147D0 (sv) 2001-06-18 2001-06-18 Pharmacia Ab New methods
DE60238929D1 (de) 2001-10-29 2011-02-24 Boehringer Ingelheim Int Mnk-kinase-homologe proteine, die an der regulierung der energiehomöostase und dem organellen metabolismus beteiligt sind
US20050012622A1 (en) 2003-05-19 2005-01-20 Sutton William R. Monitoring and control of sleep cycles
EP1746099A1 (en) 2004-12-23 2007-01-24 DeveloGen Aktiengesellschaft Mnk1 or Mnk2 inhibitors
EP1899353A1 (en) * 2005-06-22 2008-03-19 DeveloGen Aktiengesellschaft Thienopyrimidines for pharmaceutical compositions
US20070099877A1 (en) * 2005-11-02 2007-05-03 Cytovia, Inc. N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof
WO2007059905A2 (en) * 2005-11-25 2007-05-31 Develogen Aktiengesellschaft Thienopyrimidines treating inflammatory diseases
US8633201B2 (en) * 2006-04-07 2014-01-21 Boehringer Ingelheim International Gmbh Thienopyrimidines having Mnk1/Mnk2 inhibiting activity for pharmaceutical compositions
EP1889847A1 (en) * 2006-07-10 2008-02-20 DeveloGen Aktiengesellschaft Pyrrolopyrimidines for pharmaceutical compositions
EP2331551B1 (en) * 2008-08-26 2016-06-29 Evotec International GmbH Thienopyrimidines for pharmaceutical compositions

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