JP2013518917A - 感覚器官及び有糸分裂後組織のための再生促進物質としての新規なアミノアルキルオキサゾール及びアミノアルキルチアゾールカルボン酸アミド - Google Patents
感覚器官及び有糸分裂後組織のための再生促進物質としての新規なアミノアルキルオキサゾール及びアミノアルキルチアゾールカルボン酸アミド Download PDFInfo
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- JP2013518917A JP2013518917A JP2012552297A JP2012552297A JP2013518917A JP 2013518917 A JP2013518917 A JP 2013518917A JP 2012552297 A JP2012552297 A JP 2012552297A JP 2012552297 A JP2012552297 A JP 2012552297A JP 2013518917 A JP2013518917 A JP 2013518917A
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- cells
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- cell
- regeneration
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102010007281A DE102010007281A1 (de) | 2010-02-08 | 2010-02-08 | Neue Aminoalkyl-oxazol- und Aminoalkyl-thiazolcarbonsäureamide und ihre Anwendung zur Stimulation der endogenen situ Regeneration von Haarsinneszellen im Corti'schen Organ des Innenohres beim Säuger |
| DE102010007281.8 | 2010-02-08 | ||
| PCT/EP2011/000502 WO2011095338A1 (de) | 2010-02-08 | 2011-02-04 | Neue aminoalkyl-oxazol- und aminoalkyl-thiazolcarbonsäureamide als regenerationsfördernde substanzen für sinnesorgane und postmitotische gewebe |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013518917A true JP2013518917A (ja) | 2013-05-23 |
| JP2013518917A5 JP2013518917A5 (https=) | 2014-01-09 |
Family
ID=43754901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012552297A Pending JP2013518917A (ja) | 2010-02-08 | 2011-02-04 | 感覚器官及び有糸分裂後組織のための再生促進物質としての新規なアミノアルキルオキサゾール及びアミノアルキルチアゾールカルボン酸アミド |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20130012514A1 (https=) |
| EP (1) | EP2534139A1 (https=) |
| JP (1) | JP2013518917A (https=) |
| CN (1) | CN102947281B (https=) |
| CA (1) | CA2789013A1 (https=) |
| DE (1) | DE102010007281A1 (https=) |
| WO (1) | WO2011095338A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2871181B1 (en) | 2013-11-12 | 2016-10-05 | Acousia Therapeutics GmbH | Novel Compounds for Regeneration of Terminally-Differentiated Cells and tissues |
| EP3366683A1 (en) * | 2017-02-28 | 2018-08-29 | Acousia Therapeutics GmbH | Cyclic amides, acteamides and ureas useful as potassium channel openers |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002503687A (ja) * | 1998-02-23 | 2002-02-05 | オトゲネ アクチェン ゲゼルシャフト | 内耳の疾患又は機能障害の治療方法 |
| JP2002525329A (ja) * | 1998-09-25 | 2002-08-13 | セフアロン・インコーポレーテツド | 感覚毛細胞及び蝸牛ニューロンへの損傷を予防する／処置するための方法 |
| JP2004502785A (ja) * | 2000-07-11 | 2004-01-29 | サウンド・ファーマシューティカルズ・インコーポレイテッド | 内耳における細胞の再生および分化の刺激 |
| WO2008009942A1 (en) * | 2006-07-21 | 2008-01-24 | Cambridge Enterprise Ltd. | Heteroaromatic-based peptide macrocycles as g-quadruplex ligands |
| JP2008502595A (ja) * | 2004-03-31 | 2008-01-31 | エグゼリクシス， インコーポレイテッド | 未分化リンパ腫キナーゼモジュレータおよびその使用方法 |
| EP2009005A1 (en) * | 2006-04-19 | 2008-12-31 | Astellas Pharma Inc. | Azolecarboxamide derivative |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5378803A (en) * | 1987-12-11 | 1995-01-03 | Sterling Winthrop Inc. | Azole-fused peptides and processes for preparation thereof |
| TW502019B (en) * | 1999-03-26 | 2002-09-11 | Cocensys Inc | Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles, and the use thereof |
| UA89035C2 (ru) * | 2003-12-03 | 2009-12-25 | Лео Фарма А/С | Эфиры гидроксамовых кислот и их фармацевтическое применение |
-
2010
- 2010-02-08 DE DE102010007281A patent/DE102010007281A1/de not_active Withdrawn
-
2011
- 2011-02-04 US US13/577,503 patent/US20130012514A1/en not_active Abandoned
- 2011-02-04 CN CN201180017156.5A patent/CN102947281B/zh not_active Expired - Fee Related
- 2011-02-04 WO PCT/EP2011/000502 patent/WO2011095338A1/de not_active Ceased
- 2011-02-04 JP JP2012552297A patent/JP2013518917A/ja active Pending
- 2011-02-04 EP EP11703394A patent/EP2534139A1/de not_active Withdrawn
- 2011-02-04 CA CA2789013A patent/CA2789013A1/en not_active Abandoned
-
2014
- 2014-03-13 US US14/208,419 patent/US8889723B2/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002503687A (ja) * | 1998-02-23 | 2002-02-05 | オトゲネ アクチェン ゲゼルシャフト | 内耳の疾患又は機能障害の治療方法 |
| JP2002525329A (ja) * | 1998-09-25 | 2002-08-13 | セフアロン・インコーポレーテツド | 感覚毛細胞及び蝸牛ニューロンへの損傷を予防する／処置するための方法 |
| JP2004502785A (ja) * | 2000-07-11 | 2004-01-29 | サウンド・ファーマシューティカルズ・インコーポレイテッド | 内耳における細胞の再生および分化の刺激 |
| JP2008502595A (ja) * | 2004-03-31 | 2008-01-31 | エグゼリクシス， インコーポレイテッド | 未分化リンパ腫キナーゼモジュレータおよびその使用方法 |
| EP2009005A1 (en) * | 2006-04-19 | 2008-12-31 | Astellas Pharma Inc. | Azolecarboxamide derivative |
| WO2008009942A1 (en) * | 2006-07-21 | 2008-01-24 | Cambridge Enterprise Ltd. | Heteroaromatic-based peptide macrocycles as g-quadruplex ligands |
Non-Patent Citations (2)
| Title |
|---|
| JPN6014041499; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ １２（４）, 2002, ５６１-５６５ * |
| JPN6014041500; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ １１（１１）, 2001, １４４５-１４５０ * |
Also Published As
| Publication number | Publication date |
|---|---|
| US8889723B2 (en) | 2014-11-18 |
| CN102947281A (zh) | 2013-02-27 |
| CA2789013A1 (en) | 2011-08-11 |
| EP2534139A1 (de) | 2012-12-19 |
| DE102010007281A1 (de) | 2011-08-11 |
| WO2011095338A1 (de) | 2011-08-11 |
| CN102947281B (zh) | 2015-11-25 |
| US20140288135A1 (en) | 2014-09-25 |
| US20130012514A1 (en) | 2013-01-10 |
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