JP2013518579A5 - - Google Patents

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Publication number
JP2013518579A5
JP2013518579A5 JP2012551704A JP2012551704A JP2013518579A5 JP 2013518579 A5 JP2013518579 A5 JP 2013518579A5 JP 2012551704 A JP2012551704 A JP 2012551704A JP 2012551704 A JP2012551704 A JP 2012551704A JP 2013518579 A5 JP2013518579 A5 JP 2013518579A5
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JP
Japan
Prior art keywords
alk
mutant
nucleic acid
amino acid
protein
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JP2012551704A
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English (en)
Japanese (ja)
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JP5937017B2 (ja
JP2013518579A (ja
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Priority claimed from PCT/IB2011/000382 external-priority patent/WO2011095894A2/en
Publication of JP2013518579A publication Critical patent/JP2013518579A/ja
Publication of JP2013518579A5 publication Critical patent/JP2013518579A5/ja
Application granted granted Critical
Publication of JP5937017B2 publication Critical patent/JP5937017B2/ja
Expired - Fee Related legal-status Critical Current
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JP2012551704A 2010-02-04 2011-02-04 Alk阻害剤に対する自然耐性または獲得耐性を有する癌の同定、評価および治療法 Expired - Fee Related JP5937017B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33746510P 2010-02-04 2010-02-04
US61/337,465 2010-02-04
PCT/IB2011/000382 WO2011095894A2 (en) 2010-02-04 2011-02-04 Identification, assessment, and therapy of cancers with innate or acquired resistance to alk inhibitors

Publications (3)

Publication Number Publication Date
JP2013518579A JP2013518579A (ja) 2013-05-23
JP2013518579A5 true JP2013518579A5 (enExample) 2014-04-03
JP5937017B2 JP5937017B2 (ja) 2016-06-22

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ID=44355876

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012551704A Expired - Fee Related JP5937017B2 (ja) 2010-02-04 2011-02-04 Alk阻害剤に対する自然耐性または獲得耐性を有する癌の同定、評価および治療法

Country Status (17)

Country Link
US (1) US9018230B2 (enExample)
EP (1) EP2531858B1 (enExample)
JP (1) JP5937017B2 (enExample)
KR (1) KR101843967B1 (enExample)
CN (2) CN103937877B (enExample)
AR (1) AR080361A1 (enExample)
AU (1) AU2011212165B2 (enExample)
BR (1) BR112012019215A2 (enExample)
CA (1) CA2786974C (enExample)
ES (1) ES2660149T3 (enExample)
MX (1) MX336498B (enExample)
NZ (1) NZ601606A (enExample)
RU (1) RU2589834C2 (enExample)
SG (1) SG182766A1 (enExample)
TW (1) TWI518325B (enExample)
WO (1) WO2011095894A2 (enExample)
ZA (1) ZA201205831B (enExample)

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US8383793B2 (en) * 2010-04-15 2013-02-26 St. Jude Children's Research Hospital Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
US20120101108A1 (en) 2010-08-06 2012-04-26 Cell Signaling Technology, Inc. Anaplastic Lymphoma Kinase In Kidney Cancer
JP6205216B2 (ja) 2012-09-24 2017-09-27 アークレイ株式会社 変異検出用プローブ、変異検出方法、薬効判定方法及び変異検出用キット
US9428812B2 (en) * 2014-04-28 2016-08-30 Insight Genetics, Inc. Kit comprising primers for amplifying ALK kinase domain nucleic acids
DK3186284T3 (da) * 2014-08-28 2022-05-09 Bioatla Inc Betinget aktive kimæriske antigenreceptorer til modificerede t-celler
JP2019519540A (ja) * 2016-06-01 2019-07-11 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 肺癌患者におけるalk阻害薬療法に対する応答を予測する未分化リンパ腫キナーゼにおける新規な変異
KR101872624B1 (ko) * 2016-12-27 2018-06-28 (주) 바이오인프라생명과학 Alk 표적 치료제에 대한 폐암의 치료 반응성을 예측하는 방법
CN107828823A (zh) * 2017-09-29 2018-03-23 暨南大学 一种评价eml4‑alk抑制剂对肺癌治疗效果的方法
RU2717309C2 (ru) * 2018-08-01 2020-03-20 Общество с ограниченной ответственностью "ОНКОДИАГНОСТИКА АТЛАС" Способ определения микросателлитной нестабильности
CN112424380B (zh) 2018-11-01 2025-03-04 Illumina公司 用于体细胞变体检测的方法和组合物
EP4139440B1 (en) 2020-04-22 2026-08-19 Iovance Biotherapeutics, Inc. Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
CA3195019A1 (en) 2020-10-06 2022-04-14 Maria Fardis Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
WO2024017352A1 (zh) * 2022-07-22 2024-01-25 四川大学 用于rdaa阳性疾病的诊断和治疗的方法和试剂盒

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