RU2589834C2 - Идентификация, оценка и лечение раковых заболеваний с генетической или приобретенной устойчивостью к ингибиторам alk - Google Patents

Идентификация, оценка и лечение раковых заболеваний с генетической или приобретенной устойчивостью к ингибиторам alk Download PDF

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RU2589834C2
RU2589834C2 RU2012133318/15A RU2012133318A RU2589834C2 RU 2589834 C2 RU2589834 C2 RU 2589834C2 RU 2012133318/15 A RU2012133318/15 A RU 2012133318/15A RU 2012133318 A RU2012133318 A RU 2012133318A RU 2589834 C2 RU2589834 C2 RU 2589834C2
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alk
cancer
marker
cells
mutant
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RU2012133318A (ru
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Хироюки МАНО
Янг Л. ЧОЙ
Манабу СОДА
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Джичи Медикал Юниверсити
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205—Phosphotransferases in general
    • G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2012133318/15A 2010-02-04 2011-02-04 Идентификация, оценка и лечение раковых заболеваний с генетической или приобретенной устойчивостью к ингибиторам alk RU2589834C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33746510P 2010-02-04 2010-02-04
US61/337,465 2010-02-04
PCT/IB2011/000382 WO2011095894A2 (en) 2010-02-04 2011-02-04 Identification, assessment, and therapy of cancers with innate or acquired resistance to alk inhibitors

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RU2012133318A RU2012133318A (ru) 2014-03-10
RU2589834C2 true RU2589834C2 (ru) 2016-07-10

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US (1) US9018230B2 (enExample)
EP (1) EP2531858B1 (enExample)
JP (1) JP5937017B2 (enExample)
KR (1) KR101843967B1 (enExample)
CN (2) CN103937877B (enExample)
AR (1) AR080361A1 (enExample)
AU (1) AU2011212165B2 (enExample)
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CA (1) CA2786974C (enExample)
ES (1) ES2660149T3 (enExample)
MX (1) MX336498B (enExample)
NZ (1) NZ601606A (enExample)
RU (1) RU2589834C2 (enExample)
SG (1) SG182766A1 (enExample)
TW (1) TWI518325B (enExample)
WO (1) WO2011095894A2 (enExample)
ZA (1) ZA201205831B (enExample)

Cited By (4)

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RU2717309C2 (ru) * 2018-08-01 2020-03-20 Общество с ограниченной ответственностью "ОНКОДИАГНОСТИКА АТЛАС" Способ определения микросателлитной нестабильности
RU2764074C2 (ru) * 2014-08-28 2022-01-13 Байоатла, Ллк Условно активные химерные антигенные рецепторы для модифицированных т-клеток
RU2813655C2 (ru) * 2018-11-01 2024-02-14 Иллюмина, Инк. Способы и композиции для обнаружения соматического варианта
US12417819B2 (en) 2018-11-01 2025-09-16 Illumina, Inc. Methods and compositions for germline variant detection

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JP6205216B2 (ja) * 2012-09-24 2017-09-27 アークレイ株式会社 変異検出用プローブ、変異検出方法、薬効判定方法及び変異検出用キット
US9428812B2 (en) * 2014-04-28 2016-08-30 Insight Genetics, Inc. Kit comprising primers for amplifying ALK kinase domain nucleic acids
US20170349953A1 (en) * 2016-06-01 2017-12-07 Roche Sequencing Solutions, Inc. Novel mutations in anaplastic lymphoma kinase predicting response to alk inhibitor therapy in lung cancer patients
KR101872624B1 (ko) * 2016-12-27 2018-06-28 (주) 바이오인프라생명과학 Alk 표적 치료제에 대한 폐암의 치료 반응성을 예측하는 방법
CN107828823A (zh) * 2017-09-29 2018-03-23 暨南大学 一种评价eml4‑alk抑制剂对肺癌治疗效果的方法
IL297442A (en) 2020-04-22 2022-12-01 Iovance Biotherapeutics Inc Systems and methods for coordinating production of cells for patient-specific immunotherapy
WO2024017352A1 (zh) * 2022-07-22 2024-01-25 四川大学 用于rdaa阳性疾病的诊断和治疗的方法和试剂盒

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