JP2013518057A5 - - Google Patents
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- Publication number
- JP2013518057A5 JP2013518057A5 JP2012550189A JP2012550189A JP2013518057A5 JP 2013518057 A5 JP2013518057 A5 JP 2013518057A5 JP 2012550189 A JP2012550189 A JP 2012550189A JP 2012550189 A JP2012550189 A JP 2012550189A JP 2013518057 A5 JP2013518057 A5 JP 2013518057A5
- Authority
- JP
- Japan
- Prior art keywords
- lys
- dmt
- arg
- phe
- trp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 230000002438 mitochondrial effect Effects 0.000 claims 4
- 230000037050 permeability transition Effects 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000004792 oxidative damage Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29806210P | 2010-01-25 | 2010-01-25 | |
| US61/298,062 | 2010-01-25 | ||
| PCT/US2011/022247 WO2011091357A1 (en) | 2010-01-25 | 2011-01-24 | Aromatic-cationic peptides and uses of same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015163826A Division JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013518057A JP2013518057A (ja) | 2013-05-20 |
| JP2013518057A5 true JP2013518057A5 (enExample) | 2014-03-13 |
Family
ID=44307257
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012550189A Pending JP2013518057A (ja) | 2010-01-25 | 2011-01-24 | 芳香族カチオン性ペプチドおよびその使用 |
| JP2015163826A Pending JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015163826A Pending JP2016000750A (ja) | 2010-01-25 | 2015-08-21 | 芳香族カチオン性ペプチドおよびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US20120329730A1 (enExample) |
| EP (4) | EP2528934A4 (enExample) |
| JP (2) | JP2013518057A (enExample) |
| CN (2) | CN102834408A (enExample) |
| AU (2) | AU2011207432A1 (enExample) |
| CA (2) | CA2787331A1 (enExample) |
| HK (1) | HK1208686A1 (enExample) |
| WO (1) | WO2011091357A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3708178T1 (sl) * | 2009-08-24 | 2024-01-31 | Stealth Biotherapeutics Inc. | Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule |
| EP3332795A1 (en) * | 2010-02-26 | 2018-06-13 | Cornell University Cornell Center For Technology, Enterprise & Commercialization ("CCTEC") | Mitochondrial-targeted antioxidants protect against mechanical ventilation-induced diaphragm dysfunction and skeletal muscle atrophy |
| EP2808029A3 (en) | 2010-03-15 | 2015-04-01 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
| JP2013532124A (ja) * | 2010-05-03 | 2013-08-15 | ステルス ペプチドズ インターナショナル インコーポレイテッド | 芳香族系陽イオンペプチド及びその使用 |
| CN102327600A (zh) * | 2011-09-14 | 2012-01-25 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 用于预防和治疗辐射损伤的rx31肽 |
| CN107496899A (zh) | 2011-09-29 | 2017-12-22 | 梅约医学教育与研究基金会 | 芳族阳离子肽和使用它们的方法 |
| CA2858550A1 (en) * | 2011-12-09 | 2013-06-13 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
| CA2869080C (en) * | 2012-03-30 | 2020-09-01 | Stealth Peptides International, Inc. | Methods and compositions for the prevention and treatment neuropathy |
| US20150119552A1 (en) * | 2012-04-12 | 2015-04-30 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
| EP4091624A1 (en) | 2013-03-15 | 2022-11-23 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses thereof |
| US20140294902A1 (en) * | 2013-04-02 | 2014-10-02 | Protagonist Therapeutics, Inc. | Novel a4b7 peptide antagonists |
| CA2916492A1 (en) | 2013-06-27 | 2014-12-31 | Stealth Biotherapeutics Corp | Peptide therapeutics and methods for using same |
| CA2920735A1 (en) * | 2013-08-12 | 2015-02-19 | Stealth Biotherapeutics Corp | Combination therapy for the treatment of ischemia-reperfusion injury |
| CA2932408A1 (en) * | 2013-12-02 | 2015-06-11 | Stealth Biotherapeutics Corp | Compositions and methods for treating vitiligo |
| CA2949215C (en) | 2014-05-16 | 2023-03-14 | Protagonist Therapeutics, Inc. | .alpha.4.beta.7 integrin thioether peptide antagonists |
| SG10201810154WA (en) | 2014-07-17 | 2018-12-28 | Protagonist Therapeutics Inc | Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases |
| JP2017535527A (ja) | 2014-10-01 | 2017-11-30 | プロタゴニスト セラピューティクス， インコーポレイテッド | 新規のα４β７ペプチド単量体及び二量体拮抗薬 |
| JP6854771B2 (ja) * | 2015-03-06 | 2021-04-07 | ステルス バイオセラピューティックス コープ | 薬学的に適切なペプチドを調製するための方法 |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP6533723B2 (ja) * | 2015-09-11 | 2019-06-19 | キユーピー株式会社 | 抗酸化剤 |
| WO2017093897A1 (en) * | 2015-11-30 | 2017-06-08 | Peter Schiller | Aromatic-cationic peptides conjugated to antioxidants and their use in treating complex regional pain syndrome |
| CA3009834A1 (en) | 2015-12-30 | 2017-07-06 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| CA3010321A1 (en) * | 2015-12-31 | 2017-07-06 | Scott Duncan | Therapeutic compositions including peptides and uses thereof |
| WO2017156403A1 (en) * | 2016-03-11 | 2017-09-14 | Stealth Biotherapeutics | Crystalline salt forms |
| US10870678B2 (en) | 2016-04-11 | 2020-12-22 | Arcuate Therapeutics, Inc. | Chiral peptides |
| WO2018022937A1 (en) | 2016-07-27 | 2018-02-01 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 and their use to treat inflammatory diseases |
| US11034724B2 (en) | 2017-04-05 | 2021-06-15 | Stealth Biotherapeutics Corp. | Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2 |
| EP3681900A4 (en) * | 2017-09-11 | 2021-09-08 | Protagonist Therapeutics, Inc. | OPIOID AGONIST PEPTIDES AND THEIR USES |
| WO2019157268A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| CA3104418A1 (en) | 2018-07-12 | 2020-01-16 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| WO2020131283A1 (en) | 2018-12-18 | 2020-06-25 | Stealth Biotherapeutics Corp. | Analogs that target mitochondrial diseases |
| AU2020311395A1 (en) | 2019-07-10 | 2022-02-03 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| MX2022008740A (es) | 2020-01-15 | 2022-09-23 | Janssen Biotech Inc | Peptidos inhibidores del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias. |
| SMT202500254T1 (it) | 2020-01-15 | 2025-09-12 | Janssen Biotech Inc | Inibitori peptidici del recettore dell'interleuchina-23 e loro uso per trattare malattie infiammatorie |
| AU2021383828A1 (en) | 2020-11-20 | 2023-07-06 | Janssen Pharmaceutica Nv | Compositions of peptide inhibitors of interleukin-23 receptor |
| CN117881411A (zh) | 2021-06-01 | 2024-04-12 | 艾迪雅生物有限责任公司 | 用于眼部药物的延长释放药物递送系统和使用方法 |
| KR20240034224A (ko) | 2021-07-14 | 2024-03-13 | 얀센 바이오테크 인코포레이티드 | 인터류킨-23 수용체의 지질화된 펩티드 억제제 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| EP0273696A2 (en) * | 1987-01-02 | 1988-07-06 | Merck & Co. Inc. | Renin inhibitors containing histidine replacements |
| HUT58763A (en) * | 1989-11-06 | 1992-03-30 | Erba Carlo Spa | Process for producing reduced irreverzible bombezin antagonists and pharmaceutical compositions containing them as active components |
| EP0592512A1 (en) * | 1991-07-01 | 1994-04-20 | University Technologies International Inc. (Uti) | NON-DESENSITIZING ANALOGS OF GnRH AND OTHER BIOLOGICALLY ACTIVE LIGANDS |
| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| SI2656854T1 (sl) * | 2003-02-04 | 2015-09-30 | Cornell Research Foundation, Inc. | Uporabe aromatsko-kationskega peptida |
| CA3024434A1 (en) * | 2004-01-23 | 2005-08-11 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
| EP2712620A1 (en) * | 2008-02-07 | 2014-04-02 | Cornell University | Methods for Preventing or Treating Insulin Resistance |
| CN107802821A (zh) * | 2008-02-26 | 2018-03-16 | 康奈尔大学 | 用于防止和治疗急性肾损伤的方法 |
-
2011
- 2011-01-24 CA CA2787331A patent/CA2787331A1/en not_active Abandoned
- 2011-01-24 CN CN2011800071355A patent/CN102834408A/zh active Pending
- 2011-01-24 EP EP11735303.7A patent/EP2528934A4/en not_active Withdrawn
- 2011-01-24 CA CA3008993A patent/CA3008993A1/en not_active Abandoned
- 2011-01-24 WO PCT/US2011/022247 patent/WO2011091357A1/en not_active Ceased
- 2011-01-24 JP JP2012550189A patent/JP2013518057A/ja active Pending
- 2011-01-24 US US13/519,083 patent/US20120329730A1/en not_active Abandoned
- 2011-01-24 EP EP14194189.8A patent/EP2848628A1/en not_active Withdrawn
- 2011-01-24 EP EP15185546.7A patent/EP3018138A1/en not_active Withdrawn
- 2011-01-24 AU AU2011207432A patent/AU2011207432A1/en not_active Abandoned
- 2011-01-24 CN CN201510081030.4A patent/CN104725472A/zh active Pending
- 2011-01-24 EP EP14155476.6A patent/EP2733150A1/en not_active Withdrawn
-
2013
- 2013-08-07 US US13/961,313 patent/US20130316964A1/en not_active Abandoned
-
2014
- 2014-09-16 US US14/488,007 patent/US20150005242A1/en not_active Abandoned
-
2015
- 2015-08-21 JP JP2015163826A patent/JP2016000750A/ja active Pending
- 2015-09-23 HK HK15109345.6A patent/HK1208686A1/xx unknown
-
2016
- 2016-02-05 AU AU2016200747A patent/AU2016200747A1/en not_active Abandoned
- 2016-02-11 US US15/041,235 patent/US20170008925A1/en not_active Abandoned
-
2017
- 2017-10-11 US US15/729,838 patent/US20180244721A1/en not_active Abandoned
-
2018
- 2018-11-30 US US16/206,777 patent/US20190330272A1/en not_active Abandoned
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