JP2011513241A5 - - Google Patents
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- Publication number
- JP2011513241A5 JP2011513241A5 JP2010547861A JP2010547861A JP2011513241A5 JP 2011513241 A5 JP2011513241 A5 JP 2011513241A5 JP 2010547861 A JP2010547861 A JP 2010547861A JP 2010547861 A JP2010547861 A JP 2010547861A JP 2011513241 A5 JP2011513241 A5 JP 2011513241A5
- Authority
- JP
- Japan
- Prior art keywords
- phe
- lys
- arg
- subject
- dmt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000009304 Acute Kidney Injury Diseases 0.000 claims 1
- 208000033626 Renal failure acute Diseases 0.000 claims 1
- 201000011040 acute kidney failure Diseases 0.000 claims 1
- 208000012998 acute renal failure Diseases 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 108010048898 phenylalanyl-arginyl-phenylalanyllysinamide Proteins 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3158508P | 2008-02-26 | 2008-02-26 | |
| US61/031,585 | 2008-02-26 | ||
| PCT/US2009/035132 WO2009108695A2 (en) | 2008-02-26 | 2009-02-25 | Methods for prevention and treatment of acute renal injury |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014263863A Division JP2015063561A (ja) | 2008-02-26 | 2014-12-26 | 急性腎障害を予防および治療するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011513241A JP2011513241A (ja) | 2011-04-28 |
| JP2011513241A5 true JP2011513241A5 (enExample) | 2012-04-12 |
| JP5677096B2 JP5677096B2 (ja) | 2015-02-25 |
Family
ID=41013650
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010547861A Active JP5677096B2 (ja) | 2008-02-26 | 2009-02-25 | 急性腎障害を予防および治療するための方法 |
| JP2014263863A Pending JP2015063561A (ja) | 2008-02-26 | 2014-12-26 | 急性腎障害を予防および治療するための方法 |
| JP2016087350A Pending JP2016175924A (ja) | 2008-02-26 | 2016-04-25 | 急性腎障害を予防および治療するための方法 |
| JP2017179838A Pending JP2017226697A (ja) | 2008-02-26 | 2017-09-20 | 急性腎障害を予防および治療するための方法 |
| JP2018241524A Pending JP2019059785A (ja) | 2008-02-26 | 2018-12-25 | 急性腎障害を予防および治療するための方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014263863A Pending JP2015063561A (ja) | 2008-02-26 | 2014-12-26 | 急性腎障害を予防および治療するための方法 |
| JP2016087350A Pending JP2016175924A (ja) | 2008-02-26 | 2016-04-25 | 急性腎障害を予防および治療するための方法 |
| JP2017179838A Pending JP2017226697A (ja) | 2008-02-26 | 2017-09-20 | 急性腎障害を予防および治療するための方法 |
| JP2018241524A Pending JP2019059785A (ja) | 2008-02-26 | 2018-12-25 | 急性腎障害を予防および治療するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (9) | US8143219B2 (enExample) |
| EP (3) | EP2262520B1 (enExample) |
| JP (5) | JP5677096B2 (enExample) |
| CN (4) | CN106975070A (enExample) |
| DK (1) | DK2262520T3 (enExample) |
| HK (1) | HK1202429A1 (enExample) |
| WO (1) | WO2009108695A2 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA200509229B (en) | 2003-05-01 | 2007-03-28 | Cornell Res Foundation Inc | Method and carrier complexes for delivering molecules to cells |
| KR20150013353A (ko) | 2005-09-16 | 2015-02-04 | 코넬 리서치 화운데이션,인크. | Cd36 발현을 감소시키는 방법 |
| WO2009108695A2 (en) | 2008-02-26 | 2009-09-03 | Cornell University | Methods for prevention and treatment of acute renal injury |
| CN102573881A (zh) * | 2009-03-20 | 2012-07-11 | 通用医疗公司以马萨诸塞州通用医疗公司名义经营 | 预防和治疗烧伤损伤和继发性并发症的方法 |
| JP5909182B2 (ja) * | 2009-08-12 | 2016-04-26 | コーネル ユニヴァーシティー | 代謝性症候群を予防し又は治療するための方法 |
| EP4302829B1 (en) * | 2009-08-24 | 2025-05-21 | Stealth BioTherapeutics Inc. | Peptide for use in preventing or treating macular degeneration |
| EP3603658B1 (en) | 2009-10-05 | 2025-01-08 | Cornell University | Peptide for use in the treatment of heart failure resulting from hypertrophic cardiomyopathy |
| JP2013516425A (ja) * | 2009-12-31 | 2013-05-13 | ステルス ペプチドズ インターナショナル インコーポレイテッド | 血管閉塞傷害の予防または治療方法 |
| JP2013516426A (ja) * | 2009-12-31 | 2013-05-13 | ステルス ペプチドズ インターナショナル インコーポレイテッド | 冠状動脈バイパス移植術を行うための方法 |
| EP2528934A4 (en) * | 2010-01-25 | 2013-08-21 | Univ Cornell | AROMATIC-CATIONIC PEPTIDES AND USES THEREOF |
| US8585597B2 (en) * | 2010-03-12 | 2013-11-19 | Sonogenix, Inc. | Renal injury inhibiting devices, systems, and methods employing low-frequency ultrasound or other cyclical pressure energies |
| EP3375449A1 (en) | 2010-03-15 | 2018-09-19 | Stealth Peptides International, Inc. | Combination therapies using cyclosporine and aromatic cationic peptides |
| EP2566880A4 (en) * | 2010-05-03 | 2014-10-08 | Stealth Peptides Int Inc | AROMATIC-CATIONIC PEPTIDES AND USES THEREOF |
| AU2011352333B2 (en) * | 2010-12-31 | 2016-12-08 | Zeus Scientific, Inc. | Improved methods for determining cell viability using molecular nucleic acid-based techniques |
| EP3488941A1 (en) * | 2011-03-24 | 2019-05-29 | Cornell University | Aromatic-cationic peptides and uses of same |
| WO2012158518A1 (en) * | 2011-05-13 | 2012-11-22 | The Penn State Research Foundation | Treatment of renal injury |
| CN103857407A (zh) * | 2011-08-10 | 2014-06-11 | 迪格纳生物技术公司 | 心肌营养素-1治疗肾脏疾病的用途 |
| WO2013049697A1 (en) | 2011-09-29 | 2013-04-04 | Mayo Foundation For Medical Education And Research | Aromatic-cationic peptides and methods for using same |
| CN104114181B (zh) * | 2011-10-17 | 2017-06-09 | 康奈尔大学 | 芳香族阳离子肽及其用途 |
| US9353171B2 (en) | 2011-11-17 | 2016-05-31 | The Administrators Of The Tulane Educational Fund | Use of pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP analogs for treating contrast-induced nephropathy |
| EP3466439A1 (en) | 2011-12-09 | 2019-04-10 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
| EP3281634A1 (en) * | 2012-02-22 | 2018-02-14 | Stealth Peptides International, Inc. | Method and compositions for preventing or treating ophthalmic conditions |
| US10808008B2 (en) * | 2012-02-23 | 2020-10-20 | Cornell University | Aromatic-cationic peptides and uses of same |
| WO2013149172A1 (en) * | 2012-03-30 | 2013-10-03 | Stealth Peptides International, Inc. | Methods and compositions for the prevention and treatment neuropathy |
| MX2015005102A (es) * | 2012-10-22 | 2016-02-09 | Stealth Peptides Int Inc | Metodos para la reduccion de los riesgos asociados con el insuficiencia cardiaca y factores asociado con el mismo. |
| CA2916884C (en) * | 2013-03-01 | 2021-02-09 | Stealth Biotherapeutics Corp | Methods for the treatment of mitochondrial disease |
| HUE046924T2 (hu) | 2013-03-01 | 2020-03-30 | Stealth Biotherapeutics Corp | Módszerek és készítmények Barth szindróma megelõzésében vagy kezelésében történõ alkalmazásra |
| US10047395B2 (en) | 2013-06-26 | 2018-08-14 | Stealth Biotherapeutics Corp | Methods and compositions for detecting and diagnosing diseases and conditions |
| US9895410B2 (en) | 2013-12-12 | 2018-02-20 | Cornell University | Methods for preventing and treating oral cancers |
| WO2015153287A1 (en) * | 2014-03-31 | 2015-10-08 | Zoll Medical Corporation | Blood filtering of inflammatory biomarkers to treat post-resuscitation syndrome |
| PL3160984T3 (pl) | 2014-06-25 | 2021-10-25 | Flamma S.P.A. | Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylol- fenyloalaninoamidu |
| EP3160985B1 (en) | 2014-06-30 | 2021-07-28 | Flamma S.P.A. | Process for the production of d-arginyl-2,6-dimethyl-l-tyrosyl-l-lysyl-l-phenylalaninamide |
| ES2870481T3 (es) | 2014-08-21 | 2021-10-27 | Stealth Biotherapeutics Corp | Péptido D-Arg-2,6-Dmt-Lys-Phe-NH2 para el tratamiento del síndrome de Alport |
| US10870678B2 (en) | 2016-04-11 | 2020-12-22 | Arcuate Therapeutics, Inc. | Chiral peptides |
| SG11201809982RA (en) * | 2016-05-09 | 2018-12-28 | Us Health | Chemical conjugates of evans blue derivatives and their use as radiotherapy and imaging agents |
| CN107644976B (zh) * | 2016-07-22 | 2020-09-29 | 清华大学 | 锂离子电池电极 |
| US20180140599A1 (en) | 2016-11-21 | 2018-05-24 | Saghmos Therapeutics, Inc. | Prevention and/or treatment of contrast-induced acute kidney injury |
| EP3692032B1 (en) | 2017-10-03 | 2024-06-19 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Chemical conjugates of evans blue derivatives and their use as radiotherapy and imaging agents |
| IL276653B2 (en) | 2018-02-22 | 2024-11-01 | Us Health | Chemical conjugates of evans blue derivatives and their use as radiotherapy and imaging agents for targeting prostate cancer |
| WO2020018381A1 (en) | 2018-07-18 | 2020-01-23 | The Regents Of The University Of California | Kidney injury treatment |
| CN109946139A (zh) * | 2019-02-28 | 2019-06-28 | 东南大学 | 一种石蜡切片免疫组化套染pas试剂盒及其染色方法和应用 |
| CN111686239B (zh) * | 2019-03-11 | 2021-12-24 | 中国科学院微生物研究所 | 抗真菌化合物的应用 |
| WO2020214518A1 (en) * | 2019-04-18 | 2020-10-22 | Arcuate Therapeutics, Inc. | Methods of treating renal conditions using peptides that improve mitochondrial function |
| CN110250110A (zh) * | 2019-07-11 | 2019-09-20 | 南京医科大学附属逸夫医院 | 一种顺铂所致急性肾损伤的小鼠模型的构建方法 |
| EP3771467A1 (en) * | 2019-07-30 | 2021-02-03 | Fundacio Institut de Recerca de l'Hospital de la Santa Creu i sant Pau | Ss-31 for the prevention and/or treatment of aneurysm |
| CN113209294B (zh) * | 2020-02-05 | 2023-06-13 | 复旦大学 | Dor激动剂在制备对抗肾脏纤维化药物中的应用 |
| CN111419860A (zh) * | 2020-03-19 | 2020-07-17 | 长春市儿童医院 | 一种肾小球分叶状肾病造模方法 |
| KR102308991B1 (ko) | 2020-04-08 | 2021-10-06 | 압타바이오 주식회사 | 조영제 유발 급성 신부전 치료제 |
| MX2022012472A (es) | 2020-04-08 | 2022-12-15 | Aptabio Therapeutics Inc | Agente para el tratamiento de lesion renal aguda inducida por medio de contraste. |
| CN111933006B (zh) * | 2020-07-30 | 2022-06-03 | 四川大学华西医院 | 一种模拟巨噬细胞改善小鼠急性肾损伤实验的方法及系统 |
| EP4210695A4 (en) | 2020-09-09 | 2025-04-16 | Social Profit Network | Methods and compositions for delivery of biotin to mitochondria |
| US20220079984A1 (en) * | 2020-09-11 | 2022-03-17 | Renibus Therapeutics, Inc. | Method for treating cancer with kidney protection |
| CN117881411A (zh) | 2021-06-01 | 2024-04-12 | 艾迪雅生物有限责任公司 | 用于眼部药物的延长释放药物递送系统和使用方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5602100A (en) | 1988-06-30 | 1997-02-11 | Astra Ab | Dermorphin analogs having pharmacological activity |
| ES2085865T3 (es) | 1988-06-30 | 1996-06-16 | Astra Ab | Analogos de dermorfina, sus metodos de preparacion, composiciones farmaceuticas, y metodos de tratamiento terapeutico que los emplean. |
| US5652122A (en) | 1989-12-21 | 1997-07-29 | Frankel; Alan | Nucleic acids encoding and methods of making tat-derived transport polypeptides |
| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| WO1994028012A1 (en) * | 1993-05-28 | 1994-12-08 | Warner-Lambert Company | Hydroxamate inhibitors of endothelin converting enzyme |
| IS4261A (is) | 1994-02-21 | 1995-08-22 | Astra Aktiebolag | Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra |
| DE69630918T2 (de) | 1995-06-09 | 2004-10-28 | Hisamitsu Pharmaceutical Co., Inc., Tosu | Matrix für Iontophorese |
| US5849761A (en) | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
| US5885958A (en) | 1997-03-25 | 1999-03-23 | Administrators Of The Tulane Educational Fund | Mu-opiate receptor peptides |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| AU1818299A (en) | 1997-12-10 | 1999-06-28 | Washington University | Anti-pathogen system and methods of use thereof |
| US6268398B1 (en) | 1998-04-24 | 2001-07-31 | Mitokor | Compounds and methods for treating mitochondria-associated diseases |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| SE9900961D0 (sv) | 1999-03-16 | 1999-03-16 | Astra Ab | Novel compounds |
| CA2386239A1 (en) | 1999-10-04 | 2001-04-12 | University Of Medicine And Dentistry Of New Jersey | Methods for identifying rna binding compounds |
| US6759520B1 (en) | 1999-10-28 | 2004-07-06 | The New England Medical Center Hospitals, Inc. | Chimeric analgesic peptides |
| US20050192215A1 (en) | 2000-01-21 | 2005-09-01 | Malabika Ghosh | Methods and materials relating to novel polypeptides and polynucleotides |
| JP2004502644A (ja) | 2000-03-09 | 2004-01-29 | ジェンザイム、コーポレーション | 腎機能の喪失を治療または予防するためのTGF−β拮抗薬の使用 |
| AU2001277908A1 (en) | 2000-07-18 | 2002-01-30 | Cornell Research Foundation Inc. | Medicinal uses of mu-opioid receptor agonists |
| US6900178B2 (en) | 2000-09-12 | 2005-05-31 | University Of Kentucky Research Foundation | Protection against ischemia and reperfusion injury |
| JP2004525955A (ja) | 2001-04-05 | 2004-08-26 | コッラジェネックス ファーマシューチカルス インコーポレイテッド | テトラサイクリン化合物およびテトラサイクリン誘導体の制御された伝達 |
| US20070015146A1 (en) | 2001-05-22 | 2007-01-18 | Gene Logic, Inc. | Molecular nephrotoxicology modeling |
| PT1599216E (pt) | 2003-02-04 | 2013-12-17 | Cornell Res Foundation Inc | Métodos de prevenção da transição de permeabilidade mitocondrial |
| ZA200509229B (en) | 2003-05-01 | 2007-03-28 | Cornell Res Foundation Inc | Method and carrier complexes for delivering molecules to cells |
| WO2005032481A2 (en) | 2003-09-30 | 2005-04-14 | Scios Inc. | Quinazoline derivatives as medicaments |
| NZ549393A (en) * | 2004-01-23 | 2009-07-31 | Cornell Res Foundation Inc | Methods for reducing oxidative damage |
| US20050272101A1 (en) * | 2004-06-07 | 2005-12-08 | Prasad Devarajan | Method for the early detection of renal injury |
| KR20150013353A (ko) | 2005-09-16 | 2015-02-04 | 코넬 리서치 화운데이션,인크. | Cd36 발현을 감소시키는 방법 |
| US20080027082A1 (en) * | 2006-06-19 | 2008-01-31 | Berthold Hocher | Use of adenosine a1 antagonists in radiocontrast media induced nephropathy |
| WO2009108695A2 (en) * | 2008-02-26 | 2009-09-03 | Cornell University | Methods for prevention and treatment of acute renal injury |
-
2009
- 2009-02-25 WO PCT/US2009/035132 patent/WO2009108695A2/en not_active Ceased
- 2009-02-25 CN CN201610848820.5A patent/CN106975070A/zh active Pending
- 2009-02-25 JP JP2010547861A patent/JP5677096B2/ja active Active
- 2009-02-25 CN CN201410319216.4A patent/CN104056248A/zh active Pending
- 2009-02-25 EP EP09713874.7A patent/EP2262520B1/en active Active
- 2009-02-25 EP EP17158513.6A patent/EP3243521B1/en active Active
- 2009-02-25 US US12/392,565 patent/US8143219B2/en active Active
- 2009-02-25 CN CN2009801062159A patent/CN101951936A/zh active Pending
- 2009-02-25 DK DK09713874.7T patent/DK2262520T3/en active
- 2009-02-25 EP EP20165569.3A patent/EP3741381B1/en active Active
- 2009-02-25 CN CN201711096798.4A patent/CN107802821A/zh active Pending
-
2012
- 2012-02-22 US US13/402,620 patent/US8592373B2/en active Active
-
2013
- 2013-10-25 US US14/063,792 patent/US8940696B2/en active Active
-
2014
- 2014-12-26 JP JP2014263863A patent/JP2015063561A/ja active Pending
-
2015
- 2015-01-15 US US14/598,036 patent/US20150353602A1/en not_active Abandoned
- 2015-03-24 HK HK15102987.4A patent/HK1202429A1/xx unknown
-
2016
- 2016-04-25 JP JP2016087350A patent/JP2016175924A/ja active Pending
- 2016-06-03 US US15/172,397 patent/US20170112893A1/en not_active Abandoned
-
2017
- 2017-08-02 US US15/667,087 patent/US20180177840A1/en not_active Abandoned
- 2017-09-20 JP JP2017179838A patent/JP2017226697A/ja active Pending
-
2018
- 2018-12-25 JP JP2018241524A patent/JP2019059785A/ja active Pending
-
2019
- 2019-02-01 US US16/265,601 patent/US20190388492A1/en not_active Abandoned
-
2020
- 2020-04-17 US US16/851,382 patent/US11628198B2/en active Active
-
2023
- 2023-08-30 US US18/115,847 patent/US20230398172A1/en not_active Abandoned
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