ATE496533T1 - Medizinische verwendung von agonisten des mu- opioid rezeptors - Google Patents
Medizinische verwendung von agonisten des mu- opioid rezeptorsInfo
- Publication number
- ATE496533T1 ATE496533T1 AT01955855T AT01955855T ATE496533T1 AT E496533 T1 ATE496533 T1 AT E496533T1 AT 01955855 T AT01955855 T AT 01955855T AT 01955855 T AT01955855 T AT 01955855T AT E496533 T1 ATE496533 T1 AT E496533T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- mammal
- opioid receptor
- receptor agonists
- medical use
- Prior art date
Links
- 102000051367 mu Opioid Receptors Human genes 0.000 title abstract 2
- 108020001612 μ-opioid receptors Proteins 0.000 title abstract 2
- 239000000018 receptor agonist Substances 0.000 title 1
- 229940044601 receptor agonist Drugs 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 150000007650 D alpha amino acids Chemical class 0.000 abstract 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002756 mu opiate receptor agonist Substances 0.000 abstract 1
- 229940126487 mu opioid receptor agonist Drugs 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 1
- 150000003667 tyrosine derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21904600P | 2000-07-18 | 2000-07-18 | |
| PCT/US2001/022563 WO2002005748A2 (en) | 2000-07-18 | 2001-07-18 | Medicinal uses of mu-opioid receptor agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496533T1 true ATE496533T1 (de) | 2011-02-15 |
Family
ID=22817610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01955855T ATE496533T1 (de) | 2000-07-18 | 2001-07-18 | Medizinische verwendung von agonisten des mu- opioid rezeptors |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7498297B2 (de) |
| EP (1) | EP1303186B1 (de) |
| AT (1) | ATE496533T1 (de) |
| AU (1) | AU2001277908A1 (de) |
| CA (1) | CA2416475C (de) |
| DE (1) | DE60143945D1 (de) |
| WO (1) | WO2002005748A2 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1469875A1 (de) | 2002-01-29 | 2004-10-27 | Wyeth | Zusammensetzungen und methoden zur modulation der connexin hemikanäle |
| WO2005072295A2 (en) * | 2004-01-23 | 2005-08-11 | Cornell Research Foundation, Inc. | Methods for reducing oxidative damage |
| EP3479838A1 (de) * | 2003-02-04 | 2019-05-08 | Cornell Research Foundation, Inc. | Verwendung von aromatisch kationischem peptid |
| EP1625149B1 (de) | 2003-05-01 | 2016-02-17 | Cornell Research Foundation, Inc. | Verfahren und trägerkomplexe zum transport von molekülen zu zellen |
| WO2005015203A2 (en) * | 2003-08-06 | 2005-02-17 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor mu 1 (oprm1) |
| US20050282756A1 (en) * | 2004-06-18 | 2005-12-22 | Mehta Nozer M | Oral delivery of peptide pharmaceutical compositions |
| ATE456829T1 (de) * | 2004-09-22 | 2010-02-15 | Koninkl Philips Electronics Nv | Datenverarbeitungsschaltung mit funktionseinheiten mit gemeinsamen leseports |
| CN103784937B (zh) | 2005-09-16 | 2017-04-26 | 科内尔研究基金会 | 用于减少cd36表达的方法 |
| US8093207B2 (en) | 2005-12-09 | 2012-01-10 | Unigene Laboratories, Inc. | Fast-acting oral peptide pharmaceutical products |
| JP5453320B2 (ja) | 2008-02-07 | 2014-03-26 | コーネル ユニヴァーシティー | インスリン抵抗性を防止または処置するための方法 |
| US8143219B2 (en) | 2008-02-26 | 2012-03-27 | Cornell University | Methods for prevention and treatment of acute renal injury |
| JP2012521355A (ja) | 2009-03-20 | 2012-09-13 | ザ ジェネラル ホスピタル コーポレイション ディー ビー エイ マサチューセッツ ジェネラル ホスピタル | 熱傷及び二次性合併症の予防及び治療方法 |
| WO2011019809A1 (en) * | 2009-08-12 | 2011-02-17 | Cornell University | Methods for preventing or treating metabolic syndrome |
| EP3292868A1 (de) | 2009-08-24 | 2018-03-14 | Stealth Peptides International, Inc. | Verfahren und zusammensetzungen zur prävention oder behandlung ophthalmischer leiden |
| CA2776581C (en) * | 2009-10-05 | 2020-12-15 | Cornell University | Methods for the prevention or treatment of heart failure |
| US20160176930A1 (en) | 2010-07-09 | 2016-06-23 | The Administrators Of The Tulane Educational Fund | Mu opioid receptor agonist analogs of the endomorphins |
| US20120083452A1 (en) | 2010-09-30 | 2012-04-05 | Perricone Nicholas V | Topical Anesthetic Uses of Szeto-Schiller Peptides |
| WO2014210056A1 (en) * | 2013-06-27 | 2014-12-31 | Stealth Peptides International, Inc. | Peptide therapeutics and methods for using same |
| WO2015183963A2 (en) * | 2014-05-28 | 2015-12-03 | Stealth Peptides International, Inc. | Therapeutic compositions including redox-active parabenzoquinones and uses thereof |
| CA2958282C (en) * | 2014-07-17 | 2023-02-07 | Cardimetrix Llc | Device for monitoring for effectiveness of heart failure therapy |
| IL322723A (en) | 2017-04-05 | 2025-10-01 | Stealth Biotherapeutics Inc | Crystalline salt forms of boc-d-arg-dmt-lys-(boc)-phe-nh2 |
| US10676506B2 (en) | 2018-01-26 | 2020-06-09 | Stealth Biotherapeutics Corp. | Crystalline bis- and tris-hydrochloride salt of elamipretide |
| MX2023002772A (es) | 2020-09-09 | 2024-04-05 | Social Profit Network | Métodos y composiciones para el suministro de biotina a las mitocondrias. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2085865T3 (es) | 1988-06-30 | 1996-06-16 | Astra Ab | Analogos de dermorfina, sus metodos de preparacion, composiciones farmaceuticas, y metodos de tratamiento terapeutico que los emplean. |
| US5602100A (en) | 1988-06-30 | 1997-02-11 | Astra Ab | Dermorphin analogs having pharmacological activity |
| IS4261A (is) * | 1994-02-21 | 1995-08-22 | Astra Aktiebolag | Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra |
| SE9503924D0 (sv) | 1995-08-18 | 1995-11-07 | Astra Ab | Novel opioid peptides |
| DE69630918T2 (de) | 1995-06-09 | 2004-10-28 | Hisamitsu Pharmaceutical Co., Inc., Tosu | Matrix für Iontophorese |
| SE9900961D0 (sv) | 1999-03-16 | 1999-03-16 | Astra Ab | Novel compounds |
| US6900178B2 (en) * | 2000-09-12 | 2005-05-31 | University Of Kentucky Research Foundation | Protection against ischemia and reperfusion injury |
-
2001
- 2001-07-18 AT AT01955855T patent/ATE496533T1/de not_active IP Right Cessation
- 2001-07-18 DE DE60143945T patent/DE60143945D1/de not_active Expired - Lifetime
- 2001-07-18 US US10/333,485 patent/US7498297B2/en not_active Expired - Lifetime
- 2001-07-18 CA CA2416475A patent/CA2416475C/en not_active Expired - Lifetime
- 2001-07-18 EP EP01955855A patent/EP1303186B1/de not_active Expired - Lifetime
- 2001-07-18 WO PCT/US2001/022563 patent/WO2002005748A2/en not_active Ceased
- 2001-07-18 AU AU2001277908A patent/AU2001277908A1/en not_active Abandoned
-
2006
- 2006-06-29 US US11/427,606 patent/US7732398B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2416475C (en) | 2011-10-11 |
| US20040029796A1 (en) | 2004-02-12 |
| US7732398B2 (en) | 2010-06-08 |
| DE60143945D1 (de) | 2011-03-10 |
| EP1303186A4 (de) | 2007-02-07 |
| AU2001277908A1 (en) | 2002-01-30 |
| CA2416475A1 (en) | 2002-01-24 |
| WO2002005748A3 (en) | 2002-03-28 |
| US20070027070A1 (en) | 2007-02-01 |
| EP1303186A2 (de) | 2003-04-23 |
| US7498297B2 (en) | 2009-03-03 |
| EP1303186B1 (de) | 2011-01-26 |
| WO2002005748A2 (en) | 2002-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |