JP2013513559A5 - - Google Patents

Download PDF

Info

Publication number
JP2013513559A5
JP2013513559A5 JP2012542431A JP2012542431A JP2013513559A5 JP 2013513559 A5 JP2013513559 A5 JP 2013513559A5 JP 2012542431 A JP2012542431 A JP 2012542431A JP 2012542431 A JP2012542431 A JP 2012542431A JP 2013513559 A5 JP2013513559 A5 JP 2013513559A5
Authority
JP
Japan
Prior art keywords
seq
acid sequence
pharmaceutical composition
antibody
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012542431A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013513559A (ja
Filing date
Publication date
Priority claimed from EP09075546A external-priority patent/EP2332995A1/en
Application filed filed Critical
Publication of JP2013513559A publication Critical patent/JP2013513559A/ja
Publication of JP2013513559A5 publication Critical patent/JP2013513559A5/ja
Pending legal-status Critical Current

Links

JP2012542431A 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用 Pending JP2013513559A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09075546A EP2332995A1 (en) 2009-12-10 2009-12-10 Neutralizing prolactin receptor antibodies and their therapeutic use
EP09075546.3 2009-12-10
PCT/EP2010/067740 WO2011069794A1 (en) 2009-12-10 2010-11-18 Neutralizing prolactin receptor antibodies and their therapeutic use

Publications (2)

Publication Number Publication Date
JP2013513559A JP2013513559A (ja) 2013-04-22
JP2013513559A5 true JP2013513559A5 (enExample) 2014-11-06

Family

ID=42091520

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2012542431A Pending JP2013513559A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542434A Pending JP2013513363A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542435A Ceased JP2013513364A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542432A Pending JP2013513361A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542433A Pending JP2013513362A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542436A Active JP6066474B2 (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2015134286A Active JP6199930B2 (ja) 2009-12-10 2015-07-03 中和プロラクチン受容体抗体およびそれらの治療的使用

Family Applications After (6)

Application Number Title Priority Date Filing Date
JP2012542434A Pending JP2013513363A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542435A Ceased JP2013513364A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542432A Pending JP2013513361A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542433A Pending JP2013513362A (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2012542436A Active JP6066474B2 (ja) 2009-12-10 2010-11-18 中和プロラクチン受容体抗体およびそれらの治療的使用
JP2015134286A Active JP6199930B2 (ja) 2009-12-10 2015-07-03 中和プロラクチン受容体抗体およびそれらの治療的使用

Country Status (40)

Country Link
US (6) US20130171147A1 (enExample)
EP (13) EP2332995A1 (enExample)
JP (7) JP2013513559A (enExample)
KR (2) KR101765968B1 (enExample)
CN (6) CN102858801A (enExample)
AP (1) AP2012006343A0 (enExample)
AR (6) AR079351A1 (enExample)
AU (2) AU2010330161B2 (enExample)
BR (2) BR112012015852B8 (enExample)
CA (6) CA2783651A1 (enExample)
CL (2) CL2012001539A1 (enExample)
CR (2) CR20120310A (enExample)
CU (2) CU23973B1 (enExample)
CY (2) CY1118209T1 (enExample)
DK (2) DK2510002T3 (enExample)
DO (2) DOP2012000159A (enExample)
EA (2) EA029327B1 (enExample)
EC (2) ECSP12011966A (enExample)
ES (2) ES2603352T3 (enExample)
GT (1) GT201200186A (enExample)
HR (2) HRP20170016T1 (enExample)
HU (2) HUE031631T2 (enExample)
IL (2) IL220151A0 (enExample)
IN (2) IN2012DN05082A (enExample)
LT (2) LT2510002T (enExample)
MA (1) MA33888B1 (enExample)
ME (1) ME02577B (enExample)
MX (2) MX2012006621A (enExample)
NZ (2) NZ600512A (enExample)
PE (3) PE20121561A1 (enExample)
PH (2) PH12012501129A1 (enExample)
PL (2) PL2510002T3 (enExample)
PT (2) PT2510006T (enExample)
RS (2) RS55277B1 (enExample)
SG (2) SG181513A1 (enExample)
SI (2) SI2510002T1 (enExample)
TN (1) TN2012000294A1 (enExample)
TW (5) TWI508744B (enExample)
WO (6) WO2011069796A1 (enExample)
ZA (2) ZA201204213B (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2332995A1 (en) * 2009-12-10 2011-06-15 Bayer Schering Pharma Aktiengesellschaft Neutralizing prolactin receptor antibodies and their therapeutic use
SG183443A1 (en) 2010-03-01 2012-09-27 Bayer Healthcare Llc Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi)
EP2530089A1 (en) * 2011-06-03 2012-12-05 Bayer Pharma Aktiengesellschaft Neutralising prolactin receptor antibody Mat3 and its therapeutical use
SG11201405468QA (en) 2012-03-14 2014-10-30 Regeneron Pharma Multispecific antigen-binding molecules and uses thereof
US9592297B2 (en) * 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
US8883979B2 (en) * 2012-08-31 2014-11-11 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
MX382301B (es) 2012-12-24 2025-03-13 Abbvie Inc Proteinas de union al receptor de prolactina y usos de las mismas.
CA2906101A1 (en) * 2013-03-15 2014-09-18 Bayer Healthcare Llc Anti-prolactin receptor antibody formulations
TWI641620B (zh) 2013-08-21 2018-11-21 再生元醫藥公司 抗-prlr抗體及其用途
US9545451B2 (en) 2013-08-21 2017-01-17 Regeneron Pharmaceuticals, Inc. Anti-PRLR antibodies and methods for killing PRLR-expressing cells
WO2015168474A1 (en) 2014-04-30 2015-11-05 President And Fellows Of Harvard College Fusion proteins for treating cancer and related methods
KR20170063881A (ko) 2014-10-02 2017-06-08 시티 오브 호프 다가 메디토프, 메디토프 결합 항체 및 이의 용도
KR20170105558A (ko) * 2015-01-30 2017-09-19 각코우호우징 사이타마이카다이가쿠 항 alk2 항체
KR20180025865A (ko) 2015-07-06 2018-03-09 리제너론 파마슈티칼스 인코포레이티드 다중특이적 항원 결합 분자 및 이의 용도
US11352446B2 (en) 2016-04-28 2022-06-07 Regeneron Pharmaceuticals, Inc. Methods of making multispecific antigen-binding molecules
WO2018102304A1 (en) 2016-11-29 2018-06-07 Regeneron Pharmaceuticals, Inc. Methods of treating prlr positive breast cancer
FR3062213B1 (fr) * 2017-01-20 2021-02-26 Endodiag Utilisation du recepteur cd71 dans la detection et le traitement de l’endometriose
TW201836647A (zh) 2017-04-06 2018-10-16 美商艾伯維有限公司 抗-prlr抗體藥物軛合物(adc)及其用途
CA3062880A1 (en) * 2017-05-12 2018-11-15 Millennium Pharmaceuticals, Inc. Treatment of gastroparesis with triazaspiro[4.5]decanone
KR20200027494A (ko) 2017-07-10 2020-03-12 바이엘 파마 악티엔게젤샤프트 남성 및 여성 패턴 탈모를 위한 프로락틴 수용체 항체
KR20200118151A (ko) 2018-02-07 2020-10-14 리제너론 파마슈티칼스 인코포레이티드 치료 단백질 전달을 위한 방법 및 조성물
WO2019169330A1 (en) * 2018-03-02 2019-09-06 Oncolix, Inc. Method for treating cancers expressing prolactin receptor
CN109627340B (zh) * 2018-12-05 2021-02-12 上海交通大学 Cd3和prlr双特异性抗体及其构建与应用
US10467487B1 (en) * 2018-12-11 2019-11-05 Chongqing Jinkang New Energy Automobile Co., Ltd. Fusion-based traffic light recognition for autonomous driving
CN112425568A (zh) * 2020-12-11 2021-03-02 上海市计划生育科学研究所 一种建立具有emt特征的良性前列腺增生bph犬模型的方法
AR124681A1 (es) 2021-01-20 2023-04-26 Abbvie Inc Conjugados anticuerpo-fármaco anti-egfr
CN114853890B (zh) * 2022-03-16 2023-04-28 沈阳三生制药有限责任公司 一种prlr抗原结合蛋白及其制备方法和应用
CN114634574B (zh) * 2022-04-18 2022-12-20 先进生物(苏州)有限公司 抗B7H6的scFv抗体、其编码基因及其应用
CN118834297A (zh) * 2023-04-24 2024-10-25 深圳真实生物医药科技有限公司 泌乳素受体抗体及其用途
CN117285625B (zh) * 2023-11-24 2024-01-23 南京佰抗生物科技有限公司 抗泌乳素蛋白的单克隆抗体及应用

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657760A (en) 1979-03-20 1987-04-14 Ortho Pharmaceutical Corporation Methods and compositions using monoclonal antibody to human T cells
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4634665A (en) 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4510245A (en) 1982-11-18 1985-04-09 Chiron Corporation Adenovirus promoter system
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US5206344A (en) 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US4968615A (en) 1985-12-18 1990-11-06 Ciba-Geigy Corporation Deoxyribonucleic acid segment from a virus
US4986615A (en) 1988-10-17 1991-01-22 The Vendo Company Vending apparatus
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5225212A (en) 1989-10-20 1993-07-06 Liposome Technology, Inc. Microreservoir liposome composition and method
GB9105245D0 (en) * 1991-03-12 1991-04-24 Lynxvale Ltd Binding molecules
DE69233204T2 (de) 1991-12-13 2004-07-15 Xoma Corp., Berkeley Verfahren und materialien zur herstellung von modifizierten variablen antikörperdomänen und ihre therapeutische verwendung
CA2229043C (en) 1995-08-18 2016-06-07 Morphosys Gesellschaft Fur Proteinoptimierung Mbh Protein/(poly)peptide libraries
JP2001500865A (ja) * 1996-09-13 2001-01-23 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ 避妊の非ホルモン法
GB9701425D0 (en) 1997-01-24 1997-03-12 Bioinvent Int Ab A method for in vitro molecular evolution of protein function
US6867187B2 (en) * 2000-12-22 2005-03-15 Trustees Of The University Of Pennsylvania Composition and method for modulating somatolactogenic function
EP1325930A1 (en) * 2002-01-08 2003-07-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Mammal prolactin variants
AU2003300904A1 (en) * 2002-12-13 2004-07-09 The Ohio State University Antagonists for human prolactin
GB0305790D0 (en) * 2003-03-13 2003-04-16 Glaxosmithkline Biolog Sa Novel Composition
JP4954709B2 (ja) * 2004-10-28 2012-06-20 協和発酵キリン株式会社 子宮内膜症治療剤
WO2006089678A2 (en) * 2005-02-22 2006-08-31 Bioinvent International Ab Antibodies and peptides binding to hiv tat, and uses thereof
GB0517878D0 (en) * 2005-09-02 2005-10-12 Bioinvent Int Ab Immunotherapeutic treatment
US7422899B2 (en) 2005-10-05 2008-09-09 Biogen Idec Ma Inc. Antibodies to the human prolactin receptor
EP3018144A1 (en) * 2006-08-18 2016-05-11 XOMA Technology Ltd. Prlr-specific antibody and uses thereof
WO2009013621A2 (en) 2007-05-30 2009-01-29 Auckland Uniservices Limited Inhibitors for growth hormone and related hormones, and methods of use thereof
EP2025683A1 (en) * 2007-08-13 2009-02-18 INSERM (Institut National de la Santé et de la Recherche Medicale) Variants of prolactin as antagonists of its receptor
EP2332995A1 (en) * 2009-12-10 2011-06-15 Bayer Schering Pharma Aktiengesellschaft Neutralizing prolactin receptor antibodies and their therapeutic use
WO2011139375A1 (en) * 2010-05-06 2011-11-10 Ludwig Institute For Cancer Research Ltd Antibodies directed against carbonic anhydrase ix and methods and uses thereof
GB201020995D0 (en) * 2010-12-10 2011-01-26 Bioinvent Int Ab Biological materials and uses thereof

Similar Documents

Publication Publication Date Title
JP2013513559A5 (enExample)
US8475790B2 (en) Combination of CD137 antibody and CTLA-4 antibody for the treatment of proliferative diseases
JP2023011614A (ja) 筋萎縮症と筋緊張性ジストロフィーを処置するための組成物および方法
WO2011069795A4 (en) Neutralizing prolactin receptor antibodies and their therapeutic use
AU2004308749B2 (en) CD40 antibody formulation and methods
JP6495899B2 (ja) ホルモン分泌調節剤、及びそれを含む組成物
JP2010110329A5 (enExample)
JP2011130770A5 (enExample)
CN119679936A (zh) 针对靶向b细胞成熟抗原的多特异性抗体的给药方案和组合疗法
JP2020528768A5 (enExample)
JP2013534922A5 (enExample)
JP2019511222A5 (enExample)
RU2015122228A (ru) Терапевтические антитела к CD47
JP2016501892A5 (enExample)
JP2018500924A5 (enExample)
US10449227B2 (en) Conjugates for immunotherapy
EP3160497A1 (en) Conjugates for immunotherapy
JP2014224150A (ja) 対象の腫瘍流入領域リンパ節へのcd40アゴニストの送達
JP2022532229A (ja) 天疱瘡及び類天疱瘡疾患の治療における抗FcRn抗体の使用
EP3105319A1 (en) Use of mcoln-1 modulators to regulate cell migration
JP2020502198A5 (enExample)
JP2019535797A5 (enExample)
WO2018181648A1 (ja) Wt1癌抗原ペプチドおよびこれを含むペプチドコンジュゲート体
WO2012050892A2 (en) Methods for stimulating, increasing or enhancing killing of a cell that expresses luteinizing hormone releasing hormone (lhrh) receptors
EA201491344A1 (ru) Производные спироиндолина в качестве антагонистов рецептора гонадотропин-рилизинг гормона